Residual Bone HeightNCT07550491
Influence of Residual Bone Height on Marginal Bone Loss Around Implants Following Lateral Sinus Floor Augmentation With Deproteinized Bovine Bone Mineral
An observational study of Residual Bone Height and Marginal Bone Loss, run by Saint-Joseph University at 1 site in Lebanon.
Trial summary
Data collection will be done on all patients who underwent a lateral maxillary sinus floor augmentation in the Faculty of Dental Medicine, both in the Periodontology Department and in the Oral Surgery Department. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Residual Bone Height, Marginal Bone Loss, Implant Type
- What is being tested?
- sinus lift using DBBM
- Type of treatment
- Surgery or procedure
- How many people
- 142 participants
- Where
- 1 siteLebanon
- Study dates
- 1 Jan 2026to 17 Apr 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Adult, Older adult
Study population: Patients from the Faculty of Dental Medicine at Saint Joseph University of Beirut who underwent a lateral maxillary sinus floor augmentation
Who may be able to join
- All patients who underwent a lateral maxillary sinus floor augmentation using deproteinated bovine bone matrix (DBBM) at the faculty before 2022.
- Patients with pre-operative CBCT.
- Patients with no visible sinus infection in the pre-operative CBCT.
Who cannot join
- Patients who do not have a pre-operative CBCT.
- Patients who do not have a post-operative orthogonal periapical radiograph that dates at least 3 years after implant placement.
- Presence of inflammatory lesions at the surgical site (eg, sinusitis as assessed by CBCT).
- Cases with sinus perforation.
- History of radiation therapy in the head/neck region.
- Use of bisphosphonates
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Influence of Residual Bone Height on Marginal Bone Loss Around Implants Following Lateral Sinus Floor Augmentation With Deproteinized Bovine Bone Mineral: A Retrospective Study Up to 12 Years.
Data collection will be done on all patients who underwent a lateral maxillary sinus floor augmentation in the Faculty of Dental Medicine, both in the Periodontology Department and in the Oral Surgery Department.
Pre-surgical residual bone height will be measured on patients with a preoperative CBCT, and marginal bone loss will be measured in patients with a postoperative periapical radiograph that dates at least 3 years after implant placement.
In contrast to other studies who only associated between the presurgical residual bone height and implant survival / success rate, this study design takes a more in depth approach and measures the exact marginal bone loss on each implant. In addition, other factors will be taken into consideration (implant type, smoking status, diabetes status) to eliminate any confounding factors.
- Conditions
- Residual Bone Height, Marginal Bone Loss, Implant Type, Smoking, Diabetes
- Being tested
- sinus lift using DBBM
- Keywords
- Alveolar bone loss, bone substitutes, dental implant, diabetes mellitus, sinus floor augmentation, smoking
- Medical subject headings
- Smoking, Diabetes Mellitus, Alveolar Bone Loss
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
sinus lift using DBBMProcedure or surgery
Sinus lift was performed to the patients, then after 9 months dental implants were placed.
| Study group | Role | What they receive |
|---|---|---|
| Grafted Bone | residual bone height < 2mm Receives: Procedure: sinus lift using DBBM | |
| Native Bone | residual bone height > 2mm Receives: Procedure: sinus lift using DBBM |
What is being measured
The primary outcome is the main question the study is designed to answer.
Marginal Bone Loss
mesial and distal marginal bone loss were calculated from the implant platform to the first bone to implant contact
Measured: at least 3 years after implant placement
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Apr 2026
- Study start1 Jan 2026
- Primary completion17 Apr 2026
- Study completion17 Apr 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (10)Papers the sponsor has linked to this study.
- Other trials for Residual Bone HeightStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 142 participants (actual)
Sponsor and investigators
- Lead sponsor
- Saint-Joseph University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07550491
- Sponsor's protocol ID
- FMD-SF192
- Status last verified
- Apr 2026
- First submitted
- 19 Apr 2026
- Last updated
- 30 Apr 2026
- Results posted
- No
- Individual data sharing
- Yes
Publications
Albrektsson T, Zarb G, Worthington P, Eriksson AR. The long-term efficacy of currently used dental implants: a review and proposed criteria of success. Int J Oral Maxillofac Implants. 1986 Summer;1(1):11-25. No abstract available.
PubMed 3527955Jamcoski VH, Faot F, Marcello-Machado RM, Melo ACM, Fontao FNGK. 15-Year Retrospective Study on the Success Rate of Maxillary Sinus Augmentation and Implants: Influence of Bone Substitute Type, Presurgical Bone Height, and Membrane Perforation during Sinus Lift. Biomed Res Int. 2023 Feb 20;2023:9144661. doi: 10.1155/2023/9144661. eCollection 2023.
PubMed 36860810Park WB, Kang KL, Han JY. Factors influencing long-term survival rates of implants placed simultaneously with lateral maxillary sinus floor augmentation: A 6- to 20-year retrospective study. Clin Oral Implants Res. 2019 Oct;30(10):977-988. doi: 10.1111/clr.13505. Epub 2019 Aug 1.
PubMed 31306519Rios HF, Avila G, Galindo P, Bratu E, Wang HL. The influence of remaining alveolar bone upon lateral window sinus augmentation implant survival. Implant Dent. 2009 Oct;18(5):402-12. doi: 10.1097/ID.0b013e3181b4af93.
PubMed 22129958Galindo-Moreno P, Fernandez-Jimenez A, O'Valle F, Silvestre FJ, Sanchez-Fernandez E, Monje A, Catena A. Marginal bone loss in implants placed in grafted maxillary sinus. Clin Implant Dent Relat Res. 2015 Apr;17(2):373-83. doi: 10.1111/cid.12092. Epub 2013 May 28.
PubMed 23714301Del Fabbro M, Wallace SS, Testori T. Long-term implant survival in the grafted maxillary sinus: a systematic review. Int J Periodontics Restorative Dent. 2013 Nov-Dec;33(6):773-83. doi: 10.11607/prd.1288.
PubMed 24116362Beretta M, Poli PP, Grossi GB, Pieroni S, Maiorana C. Long-term survival rate of implants placed in conjunction with 246 sinus floor elevation procedures: results of a 15-year retrospective study. J Dent. 2015 Jan;43(1):78-86. doi: 10.1016/j.jdent.2014.08.006. Epub 2014 Aug 20.
PubMed 25150106Tatum H Jr. Maxillary and sinus implant reconstructions. Dent Clin North Am. 1986 Apr;30(2):207-29.
PubMed 3516738Boyne PJ, James RA. Grafting of the maxillary sinus floor with autogenous marrow and bone. J Oral Surg. 1980 Aug;38(8):613-6. No abstract available.
PubMed 6993637Buser D, Dula K, Hess D, Hirt HP, Belser UC. Localized ridge augmentation with autografts and barrier membranes. Periodontol 2000. 1999 Feb;19:151-63. doi: 10.1111/j.1600-0757.1999.tb00153.x. No abstract available.
PubMed 10321222
Study at a glance
From the registry record, last updated by the sponsor on 30 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of Residual Bone Height on Marginal Bone Loss Around Implants Following Lateral Sinus Floor Augmentation With Deproteinized Bovine Bone Mineral: A Retrospective Study Up to 12 Years.
- ClinicalTrials.gov ID
- NCT07550491
- Acronym / sponsor ID
- FMD-SF192
- Conditions
- Residual Bone Height, Marginal Bone Loss, Implant Type, Smoking, Diabetes
- Keywords
- Alveolar bone loss, bone substitutes, dental implant, diabetes mellitus, sinus floor augmentation, smoking
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 142 participants (actual)
- Lead sponsor
- Saint-Joseph UniversityUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 17 Apr 2026 (actual)
- Study completion
- 17 Apr 2026 (actual)
- First posted
- 24 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Data collection will be done on all patients who underwent a lateral maxillary sinus floor augmentation in the Faculty of Dental Medicine, both in the Periodontology Department and in the Oral Surgery Department.
Pre-surgical residual bone height will be measured on patients with a preoperative CBCT, and marginal bone loss will be measured in patients with a postoperative periapical radiograph that dates at least 3 years after implant placement.
In contrast to other studies who only associated between the presurgical residual bone height and implant survival / success rate, this study design takes a more in depth approach and measures the exact marginal bone loss on each implant. In addition, other factors will be taken into consideration (implant type, smoking status, diabetes status) to eliminate any confounding factors.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Grafted Bone | – | Procedure: sinus lift using DBBMresidual bone height < 2mm |
| Native Bone | – | Procedure: sinus lift using DBBMresidual bone height > 2mm |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- Patients from the Faculty of Dental Medicine at Saint Joseph University of Beirut who underwent a lateral maxillary sinus floor augmentation
Key inclusion criteria (3 listed)
- All patients who underwent a lateral maxillary sinus floor augmentation using deproteinated bovine bone matrix (DBBM) at the faculty before 2022.
- Patients with pre-operative CBCT.
- Patients with no visible sinus infection in the pre-operative CBCT.
Key exclusion criteria (6 listed)
- Patients who do not have a pre-operative CBCT.
- Patients who do not have a post-operative orthogonal periapical radiograph that dates at least 3 years after implant placement.
- Presence of inflammatory lesions at the surgical site (eg, sinusitis as assessed by CBCT).
- Cases with sinus perforation.
- History of radiation therapy in the head/neck region.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| sinus lift using DBBMSinus lift was performed to the patients, then after 9 months dental implants were placed. | Procedure or surgery | Grafted Bone, Native Bone |
Primary outcome
Marginal Bone Loss
Time frame: at least 3 years after implant placement
mesial and distal marginal bone loss were calculated from the implant platform to the first bone to implant contact
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Apr 2026.
- Background: PubMed 3527955Albrektsson T, Zarb G, Worthington P, Eriksson AR. The long-term efficacy of currently used dental implants: a review and proposed criteria of success. Int J Oral Maxillofac Implants. 1986 Summer;1(1):11-25. No abstract available.
- Background: PubMed 36860810Jamcoski VH, Faot F, Marcello-Machado RM, Melo ACM, Fontao FNGK. 15-Year Retrospective Study on the Success Rate of Maxillary Sinus Augmentation and Implants: Influence of Bone Substitute Type, Presurgical Bone Height, and Membrane Perforation during Sinus Lift. Biomed Res Int. 2023 Feb 20;2023:9144661. doi: 10.1155/2023/9144661. eCollection 2023.
- Background: PubMed 31306519Park WB, Kang KL, Han JY. Factors influencing long-term survival rates of implants placed simultaneously with lateral maxillary sinus floor augmentation: A 6- to 20-year retrospective study. Clin Oral Implants Res. 2019 Oct;30(10):977-988. doi: 10.1111/clr.13505. Epub 2019 Aug 1.
- Background: PubMed 22129958Rios HF, Avila G, Galindo P, Bratu E, Wang HL. The influence of remaining alveolar bone upon lateral window sinus augmentation implant survival. Implant Dent. 2009 Oct;18(5):402-12. doi: 10.1097/ID.0b013e3181b4af93.
- Background: PubMed 23714301Galindo-Moreno P, Fernandez-Jimenez A, O'Valle F, Silvestre FJ, Sanchez-Fernandez E, Monje A, Catena A. Marginal bone loss in implants placed in grafted maxillary sinus. Clin Implant Dent Relat Res. 2015 Apr;17(2):373-83. doi: 10.1111/cid.12092. Epub 2013 May 28.
- Background: PubMed 24116362Del Fabbro M, Wallace SS, Testori T. Long-term implant survival in the grafted maxillary sinus: a systematic review. Int J Periodontics Restorative Dent. 2013 Nov-Dec;33(6):773-83. doi: 10.11607/prd.1288.
- Background: PubMed 25150106Beretta M, Poli PP, Grossi GB, Pieroni S, Maiorana C. Long-term survival rate of implants placed in conjunction with 246 sinus floor elevation procedures: results of a 15-year retrospective study. J Dent. 2015 Jan;43(1):78-86. doi: 10.1016/j.jdent.2014.08.006. Epub 2014 Aug 20.
- Background: PubMed 3516738Tatum H Jr. Maxillary and sinus implant reconstructions. Dent Clin North Am. 1986 Apr;30(2):207-29.
- Background: PubMed 6993637Boyne PJ, James RA. Grafting of the maxillary sinus floor with autogenous marrow and bone. J Oral Surg. 1980 Aug;38(8):613-6. No abstract available.
- Background: PubMed 10321222Buser D, Dula K, Hess D, Hirt HP, Belser UC. Localized ridge augmentation with autografts and barrier membranes. Periodontol 2000. 1999 Feb;19:151-63. doi: 10.1111/j.1600-0757.1999.tb00153.x. No abstract available.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Residual Bone Height and Marginal Bone Loss, run by Saint-Joseph University at 1 site in Lebanon.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Lebanon. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Marginal Bone Loss (time frame: at least 3 years after implant placement). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07550491, which also lists 10 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Apr 2026.