Dental Implant StabilityNCT07551128
Early Loading for Implants With Calcium Titanate Surface Technology in Posterior Mandibular Bone
A study testing Early implant loading and Delayed loading in people with Dental Implant Stability, run by Alexandria University at 1 site in Egypt.
Trial summary
Dental implants have revolutionized oral rehabilitation for partially edentulous patients. Recent advances in implant design and surface treatments have prompted the investigation of early loading methods, which aim to minimize treatment time while maintaining success rates. Read more about this study
- Who is it for?
- Ages 25 to 60 years
- Conditions the study is for
- Dental Implant Stability
- What is being tested?
- Early implant loading and Delayed loading
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 22 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jun 2025to 28 Aug 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adequate bone volume allowing implant placement without grafting (width > 6 mm, height > 10 mm)
- bone quality classified as D2
Who cannot join
- uncontrolled systemic diseases
- active infection or untreated periodontal disease
- heavy smoking (>10 cigarettes/day)
- parafunctional habits
- inability to attend follow-up visits
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt
Alexandria, Azarita, 00203
About this study
Official title: Feasibility of Early Loading for Implants With Calcium Titanate Surface Technology in Posterior Mandibular Bone
Dental implants have revolutionized oral rehabilitation for partially edentulous patients. Recent advances in implant design and surface treatments have prompted the investigation of early loading methods, which aim to minimize treatment time while maintaining success rates.
- Conditions
- Dental Implant Stability
- Being tested
- Early implant loading, Delayed loading
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Early implant loadingOther
Early Loading at 4 weeks, a screw-retained definitive restoration was delivered using standard prosthetic procedures.
Delayed loadingOther
Conventional Delayed Loading at 24 weeks, the definitive restoration was delivered using standard prosthetic procedures.
| Study group | Role | What they receive |
|---|---|---|
| Test Group | Experimental | Not described Receives: Other: Early implant loading |
| Conventional | Active comparator | Not described Receives: Other: Delayed loading |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in implant stability
Ostell device was used for implant stability assessment.
Measured: up to 1 year
Secondary outcomes (2)
Change in bone gain
amount of marginal bone resorption measured mesially and distally from the implant-abutment junction to the first bone-to-implant contact using digital image analysis software
Measured: up to 1 year
Change in density
CBCT is used for bone density assessmnet
Measured: 12 and 24-weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Apr 2026
- Study start1 Jun 2025
- Primary completion28 Aug 2026
- Study completion28 Aug 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dental Implant StabilityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 22 participants (actual)
Sponsor and investigators
- Lead sponsor
- Alexandria University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07551128
- Sponsor's protocol ID
- 1043_03/2025
- Status last verified
- Oct 2026
- First submitted
- 18 Apr 2026
- Last updated
- 30 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Feasibility of Early Loading for Implants With Calcium Titanate Surface Technology in Posterior Mandibular Bone
- ClinicalTrials.gov ID
- NCT07551128
- Acronym / sponsor ID
- 1043_03/2025
- Conditions
- Dental Implant Stability
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 22 participants (actual)
- Lead sponsor
- Alexandria UniversityUniversity, hospital or other
- Study start
- 1 Jun 2025 (actual)
- Primary completion
- 28 Aug 2026 (actual)
- Study completion
- 28 Aug 2026 (actual)
- First posted
- 24 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Dental implants have revolutionized oral rehabilitation for partially edentulous patients. Recent advances in implant design and surface treatments have prompted the investigation of early loading methods, which aim to minimize treatment time while maintaining success rates.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Test Group | Experimental | Other: Early implant loading |
| Conventional | Active comparator | Other: Delayed loading |
Who may qualify
- Ages
- 25 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Adequate bone volume allowing implant placement without grafting (width > 6 mm, height > 10 mm)
- bone quality classified as D2
Key exclusion criteria (5 listed)
- uncontrolled systemic diseases
- active infection or untreated periodontal disease
- heavy smoking (>10 cigarettes/day)
- parafunctional habits
- inability to attend follow-up visits
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Early implant loadingEarly Loading at 4 weeks, a screw-retained definitive restoration was delivered using standard prosthetic procedures. | Other | Test Group |
| Delayed loadingConventional Delayed Loading at 24 weeks, the definitive restoration was delivered using standard prosthetic procedures. | Other | Conventional |
Primary outcome
Change in implant stability
Time frame: up to 1 year
Ostell device was used for implant stability assessment.
2 secondary outcomes
Change in bone gain
Time frame: up to 1 year
Change in density
Time frame: 12 and 24-weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Oct 2026.
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Lactoferrin Nanohydrogel for Soft And Hard Tissue Healing and Implant Stability in Immediate Implant Placement
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Early implant loading and Delayed loading in people with Dental Implant Stability, run by Alexandria University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in implant stability (time frame: up to 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Oct 2026.