HypertensionNCT07552571
Goal Commitment and Proactive Health Behavior in Chronic Disease Patients
A study testing Goal Commitment-Based Behavioral Intervention in people with Hypertension and Diabetes Mellitus, run by Xiong Juyang at 1 site in China.
Trial summary
Chronic diseases such as hypertension, diabetes, and dyslipidemia are major contributors to mortality and healthcare burden worldwide. Despite high awareness of health risks, many patients fail to adopt proactive health behaviors due to behavioral inertia and a gap between knowledge and action. Read more about this study
- Who is it for?
- Ages 45 years and older
- Conditions the study is for
- Hypertension, Diabetes Mellitus, Dyslipidemia
- What is being tested?
- Goal Commitment-Based Behavioral Intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 600 participants
- Where
- 1 siteChina
- Study dates
- 15 May 2025to 31 Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Residents living in the study area for at least 1.5 years
- Diagnosed with at least one chronic disease, including hypertension, diabetes mellitus, or dyslipidemia
- Conscious and able to communicate effectively
- Educational level of primary school or above
- Able to use a smartphone and common mobile applications (e.g., WeChat)
- Willing to participate and provide written informed consent
Who cannot join
- Non-residents of the study area
- Unable to participate in group-based intervention activities
- Currently hospitalized
- Diagnosed with severe cognitive impairment, dementia, or psychiatric disorders
- Participants with severe comorbidities that may interfere with study participation
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
School of Medicine and Health Management Tongji Medical College,Huazhong University of Science and Technology
Wuhan, Hubei, 430030
Juyang Xiong, Ph.D., +86-139 9562 9873, xiongjuyang@hust.edu.cn
About this study
Official title: Evolution and Driving Mechanism of Proactive Health Behavior in Chronic Disease Patients Based on Goal Commitment
Chronic diseases such as hypertension, diabetes, and dyslipidemia are major contributors to mortality and healthcare burden worldwide. Despite high awareness of health risks, many patients fail to adopt proactive health behaviors due to behavioral inertia and a gap between knowledge and action.
This study aims to investigate the evolution and driving mechanisms of proactive health behavior in patients with chronic diseases based on goal commitment theory. By integrating prospect theory and evolutionary game theory, this study will explore how behavioral strategies evolve under different levels of goal commitment.
Read more
In addition, a behavioral intervention based on the Stimulus-Organism-Response (SOR) model will be developed to enhance patient activation and promote adherence to proactive health behaviors. A parallel controlled intervention study will be conducted to evaluate the effectiveness of the goal commitment-based intervention.
The findings of this study are expected to provide theoretical and practical evidence to improve chronic disease management and promote proactive health behaviors.
Read the detailed description
Chronic diseases, including hypertension, diabetes, and dyslipidemia, account for a substantial proportion of morbidity, mortality, and healthcare expenditure. Although a large proportion of patients are aware of their health risks, more than half fail to adopt proactive health behaviors. This gap between awareness and action is often attributed to behavioral inertia and insufficient motivation.
This study aims to explore the evolution and driving mechanisms of proactive health behavior among patients with chronic diseases based on goal commitment theory. The theoretical framework integrates prospect theory and evolutionary game theory to model behavioral decision-making under uncertainty and dynamic interactions.
First, a theoretical model will be constructed to simulate the evolution of proactive health behaviors under different levels of goal commitment, using evolutionary game analysis. Second, a conceptual framework based on the Stimulus-Organism-Response (SOR) model will be developed to examine how goal commitment influences patient activation and social norms, thereby affecting proactive health behavior.
Empirical data will be collected through multi-site surveys among patients with chronic diseases. Subsequently, a parallel controlled intervention study will be conducted to evaluate the effectiveness of a goal commitment-based intervention in improving proactive health behaviors.
Inclusion criteria include adult residents diagnosed with at least one chronic condition (hypertension, diabetes, or dyslipidemia), with adequate cognitive ability and willingness to participate. Exclusion criteria include inability to participate in group activities, current hospitalization, or severe psychiatric or cognitive disorders.
The study is expected to provide insights into the mechanisms underlying proactive health behavior and offer evidence-based strategies for improving chronic disease management.
- Conditions
- Hypertension, Diabetes Mellitus, Dyslipidemia
- Being tested
- Goal Commitment-Based Behavioral Intervention, Usual Care
- Keywords
- Proactive Health Behavior, Goal Commitment, Chronic Disease Management, Behavioral Intervention, Patient Activation, SOR Model
- Medical subject headings
- Hypertension, Diabetes Mellitus, Dyslipidemias, Patient Participation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Goal Commitment-Based Behavioral InterventionBehavioural
This intervention is a structured behavioral program based on goal commitment theory, designed to promote proactive health behaviors in patients with chronic diseases. The intervention includes goal setting, personalized action planning, behavioral activation, and continuous follow-up support. Participants will receive guidance to enhance motivation, strengthen commitment to health goals, and improve adherence to chronic disease management through regular monitoring and feedback.
Usual CareOther
Participants in the control group will receive routine chronic disease management or standard health education without additional structured behavioral intervention.
| Study group | Role | What they receive |
|---|---|---|
| Goal Commitment Intervention Group | Experimental | Participants in this group will receive a goal commitment-based behavioral intervention designed to enhance proactive health behaviors. The intervention includes structured goal-setting, behavioral activation strategies, and continuous support to improve adherence to chronic disease management. Receives: Behavioral: Goal Commitment-Based Behavioral Intervention |
| Usual Care Control Group | Active comparator | Participants in this group will receive routine chronic disease management or standard health education without additional behavioral intervention. Receives: Other: Usual Care |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Proactive Health Behavior Score
The primary outcome is the difference in the mean change of proactive health behavior scores between the intervention group and the control group at 6 months after the intervention. Proactive health behaviors will be assessed using a validated Proactive Health Behavior Scale, including overall score and component scores.
Measured: Baseline to 6 months after intervention
Secondary outcomes (12)
Change in Metabolic Syndrome (MetS) Score
The primary outcome includes the difference in the mean change of metabolic syndrome (MetS) scores between the intervention group and the control group at 6 months after the intervention.
Measured: Baseline to 6 months after intervention
Change in Proactive Health Behavior Score at 3 Months
The difference in the mean change of proactive health behavior scores and its component domains between the intervention group and the control group at 3 months after the intervention.
Measured: Baseline to 3 months after intervention
Change in Fasting Blood Glucose (FBG) at 3 Months
The difference in the mean change of fasting blood glucose levels between the intervention group and the control group at 3 months after the intervention.
Measured: Baseline to 3 months after intervention
Change in Fasting Blood Glucose (FBG)
Changes in fasting blood glucose levels measured by blood tests.
Measured: Baseline, 3 months, and 6 months after intervention
Change in Triglycerides (TG)
Changes in triglyceride levels measured by blood tests.
Measured: Baseline, 3 months after intervention, and 6 months after intervention
Change in High-Density Lipoprotein Cholesterol (HDL-C)
Changes in HDL cholesterol levels measured by blood tests.
Measured: Baseline, 3 months after intervention, and 6 months after intervention
Change in Blood Pressure
Changes in systolic and diastolic blood pressure.
Measured: Baseline, 3 months after intervention, and 6 months after intervention
Change in Body Mass Index (BMI) at 3 Months
The difference in the mean change of body mass index between the intervention group and the control group at 3 months after the intervention.
Measured: Baseline to 3 months after intervention
Change in Triglycerides (TG) at 3 Months
The difference in the mean change of triglyceride levels between the intervention group and the control group at 3 months after the intervention.
Measured: Baseline to 3 months after intervention
Change in High-Density Lipoprotein Cholesterol (HDL-C) at 3 Months
The difference in the mean change of HDL cholesterol levels between the intervention group and the control group at 3 months after the intervention.
Measured: Baseline to 3 months after intervention
Change in Systolic Blood Pressure (SBP) at 3 Months
The difference in the mean change of systolic blood pressure between the intervention group and the control group at 3 months after the intervention.
Measured: Baseline to 3 months after intervention
Change in Diastolic Blood Pressure (DBP) at 3 Months
The difference in the mean change of diastolic blood pressure between the intervention group and the control group at 3 months after the intervention.
Measured: Baseline to 3 months after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Apr 2026
- Study start15 May 2025
- Primary completion31 Dec 2028 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HypertensionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be assigned to either an intervention group or a control group in a parallel design. The intervention group will receive a goal commitment-based behavioral intervention, while the control group will receive routine chronic disease management or standard health education.
- Masking
- None (open label)
- Enrolment
- 600 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Xiong Juyang
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Xiong Juyang, Huazhong University of Science and Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07552571
- Sponsor's protocol ID
- SMHM-2026-01
- Status last verified
- Apr 2026
- First submitted
- 16 Apr 2026
- Last updated
- 6 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Individual participant data (IPD) will be shared upon reasonable request. De-identified data supporting the findings of this study will be made available to qualified researchers after publication of the primary results. Data access will be subject to approval by the corresponding author and institutional review, in accordance with ethical and data protection regulations.
Study at a glance
From the registry record, last updated by the sponsor on 6 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evolution and Driving Mechanism of Proactive Health Behavior in Chronic Disease Patients Based on Goal Commitment
- ClinicalTrials.gov ID
- NCT07552571
- Acronym / sponsor ID
- SMHM-2026-01
- Conditions
- Hypertension, Diabetes Mellitus, Dyslipidemia
- Keywords
- Proactive Health Behavior, Goal Commitment, Chronic Disease Management, Behavioral Intervention, Patient Activation, SOR Model
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 600 participants (estimated)
- Lead sponsor
- Xiong JuyangUniversity, hospital or other
- Study start
- 15 May 2025 (actual)
- Primary completion
- 31 Dec 2028 (estimated)
- Study completion
- 31 Dec 2028 (estimated)
- First posted
- 27 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Chronic diseases such as hypertension, diabetes, and dyslipidemia are major contributors to mortality and healthcare burden worldwide. Despite high awareness of health risks, many patients fail to adopt proactive health behaviors due to behavioral inertia and a gap between knowledge and action.
This study aims to investigate the evolution and driving mechanisms of proactive health behavior in patients with chronic diseases based on goal commitment theory. By integrating prospect theory and evolutionary game theory, this study will explore how behavioral strategies evolve under different levels of goal commitment.
In addition, a behavioral intervention based on the Stimulus-Organism-Response (SOR) model will be developed to enhance patient activation and promote adherence to proactive health behaviors. A parallel controlled intervention study will be conducted to evaluate the effectiveness of the goal commitment-based intervention.
The findings of this study are expected to provide theoretical and practical evidence to improve chronic disease management and promote proactive health behaviors.
Detailed description
Chronic diseases, including hypertension, diabetes, and dyslipidemia, account for a substantial proportion of morbidity, mortality, and healthcare expenditure. Although a large proportion of patients are aware of their health risks, more than half fail to adopt proactive health behaviors. This gap between awareness and action is often attributed to behavioral inertia and insufficient motivation.
This study aims to explore the evolution and driving mechanisms of proactive health behavior among patients with chronic diseases based on goal commitment theory. The theoretical framework integrates prospect theory and evolutionary game theory to model behavioral decision-making under uncertainty and dynamic interactions.
First, a theoretical model will be constructed to simulate the evolution of proactive health behaviors under different levels of goal commitment, using evolutionary game analysis. Second, a conceptual framework based on the Stimulus-Organism-Response (SOR) model will be developed to examine how goal commitment influences patient activation and social norms, thereby affecting proactive health behavior.
Empirical data will be collected through multi-site surveys among patients with chronic diseases. Subsequently, a parallel controlled intervention study will be conducted to evaluate the effectiveness of a goal commitment-based intervention in improving proactive health behaviors.
Inclusion criteria include adult residents diagnosed with at least one chronic condition (hypertension, diabetes, or dyslipidemia), with adequate cognitive ability and willingness to participate. Exclusion criteria include inability to participate in group activities, current hospitalization, or severe psychiatric or cognitive disorders.
The study is expected to provide insights into the mechanisms underlying proactive health behavior and offer evidence-based strategies for improving chronic disease management.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants will be assigned to either an intervention group or a control group in a parallel design. The intervention group will receive a goal commitment-based behavioral intervention, while the control group will receive routine chronic disease management or standard health education.
| Arm | Type | Receives |
|---|---|---|
| Goal Commitment Intervention Group | Experimental | Behavioral: Goal Commitment-Based Behavioral InterventionParticipants in this group will receive a goal commitment-based behavioral intervention designed to enhance proactive health behaviors. The intervention includes structured goal-setting, behavioral activation strategies, and continuous support to improve adherence to chronic disease management. |
| Usual Care Control Group | Active comparator | Other: Usual CareParticipants in this group will receive routine chronic disease management or standard health education without additional behavioral intervention. |
Who may qualify
- Ages
- 45 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Residents living in the study area for at least 1.5 years
- Diagnosed with at least one chronic disease, including hypertension, diabetes mellitus, or dyslipidemia
- Conscious and able to communicate effectively
- Educational level of primary school or above
- Able to use a smartphone and common mobile applications (e.g., WeChat)
Key exclusion criteria (5 listed)
- Non-residents of the study area
- Unable to participate in group-based intervention activities
- Currently hospitalized
- Diagnosed with severe cognitive impairment, dementia, or psychiatric disorders
- Participants with severe comorbidities that may interfere with study participation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Goal Commitment-Based Behavioral InterventionThis intervention is a structured behavioral program based on goal commitment theory, designed to promote proactive health behaviors in patients with chronic diseases. The intervention includes goal setting, personalized action planning, behavioral activation, and continuous follow-up support. Participants will receive guidance to enhance motivation, strengthen commitment to health goals, and improve adherence to chronic disease management through regular monitoring and feedback. | Behavioural | Goal Commitment Intervention Group |
| Usual CareParticipants in the control group will receive routine chronic disease management or standard health education without additional structured behavioral intervention. | Other | Usual Care Control Group |
Primary outcome
Change in Proactive Health Behavior Score
Time frame: Baseline to 6 months after intervention
The primary outcome is the difference in the mean change of proactive health behavior scores between the intervention group and the control group at 6 months after the intervention. Proactive health behaviors will be assessed using a validated Proactive Health Behavior Scale, including overall score and component scores.
12 secondary outcomes
Change in Metabolic Syndrome (MetS) Score
Time frame: Baseline to 6 months after intervention
Change in Proactive Health Behavior Score at 3 Months
Time frame: Baseline to 3 months after intervention
Change in Fasting Blood Glucose (FBG) at 3 Months
Time frame: Baseline to 3 months after intervention
Change in Fasting Blood Glucose (FBG)
Time frame: Baseline, 3 months, and 6 months after intervention
Change in Triglycerides (TG)
Time frame: Baseline, 3 months after intervention, and 6 months after intervention
Change in High-Density Lipoprotein Cholesterol (HDL-C)
Time frame: Baseline, 3 months after intervention, and 6 months after intervention
Change in Blood Pressure
Time frame: Baseline, 3 months after intervention, and 6 months after intervention
Change in Body Mass Index (BMI) at 3 Months
Time frame: Baseline to 3 months after intervention
Change in Triglycerides (TG) at 3 Months
Time frame: Baseline to 3 months after intervention
Change in High-Density Lipoprotein Cholesterol (HDL-C) at 3 Months
Time frame: Baseline to 3 months after intervention
Change in Systolic Blood Pressure (SBP) at 3 Months
Time frame: Baseline to 3 months after intervention
Change in Diastolic Blood Pressure (DBP) at 3 Months
Time frame: Baseline to 3 months after intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 May 2026.
- Individual participant dataSharing planned: Yes. Individual participant data (IPD) will be shared upon reasonable request. De-identified data supporting the findings of this study will be made available to qualified researchers after publication of the primary results. Data access will be subject to approval by the corresponding author and institutional review, in accordance with ethical and data protection regulations.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Goal Commitment-Based Behavioral Intervention in people with Hypertension and Diabetes Mellitus, run by Xiong Juyang at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 6 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Juyang Xiong, PhD (+86-13995629873, xiongjuyang@hust.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Proactive Health Behavior Score (time frame: Baseline to 6 months after intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 May 2026.