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Scoliosis IdiopathicNCT07552662

Comparative Effectiveness of Physiotherapeutic Scoliosis-Specific Exercises With Idiopathic Scoliosis

A study testing PSSE-Schroth Exercises and General Exercises in people with Scoliosis Idiopathic and Exercise, run by Hasan Kalyoncu University at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This randomized controlled trial evaluates the effectiveness of Physiotherapeutic Scoliosis-Specific Exercises (PSSE-Schroth) compared with General Exercises in adolescents with idiopathic scoliosis over a 12-month intervention period. Primary outcomes include Cobb angle progression and brace prescription rate. Read more about this study

Who is it for?
Ages 10 to 18 yearsHealthy volunteers can take part
Conditions the study is for
Scoliosis Idiopathic, Exercise, Scroth
What is being tested?
PSSE-Schroth Exercises and General Exercises
Could I receive a placebo?
No, everyone receives an active treatment
How many people
32 participants
Where
1 siteTurkey (Türkiye)
Study dates
18 Apr 2024to 18 Nov 2025
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 10 to 18 years
  • All sexes
  • Healthy volunteers accepted
  • Child, Adult

Who may be able to join

  • Diagnosis of adolescent idiopathic scoliosis
  • Cobb angle 10°-25°
  • Risser sign 0-3 ATR >5°
  • Less than 1 year post-menarche (for females)

Who cannot join

  • Previous brace treatment * Non-idiopathic scoliosis
  • Previous scoliosis surgery
  • Neuromuscular or congenital scoliosis

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

  • Hasan Kalyoncu University

    Gaziantep, Şahinbey, 27000

Other trials in Turkey (Türkiye)

About this study

Official title: Comparative Effectiveness of Physiotherapeutic Scoliosis-Specific Exercises Versus General Exercises in Adolescents With Idiopathic Scoliosis: A Randomized Controlled Trial

This randomized controlled trial evaluates the effectiveness of Physiotherapeutic Scoliosis-Specific Exercises (PSSE-Schroth) compared with General Exercises in adolescents with idiopathic scoliosis over a 12-month intervention period. Primary outcomes include Cobb angle progression and brace prescription rate. Secondary outcomes include trunk rotation, quality of life, self-image, and body symmetry.

Read the detailed description

Adolescent idiopathic scoliosis is a three-dimensional spinal deformity that may progress during growth. Although PSSE is increasingly recommended in conservative scoliosis management, comparative randomized evidence remains limited. This study aims to compare PSSE-Schroth exercises with General Exercises in adolescents with mild idiopathic scoliosis over 12 months. Participants are randomized into intervention or control groups receiving matched exercise dosage and supervision. Outcomes assess radiographic progression, trunk rotation, need for bracing, and patient-reported clinical parameters.

Being tested
PSSE-Schroth Exercises, General Exercises
Keywords
Scoliosis Idiopathic, Cobb angle, quality of life
Medical subject headings
Motor Activity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • PSSE-Schroth ExercisesOther

    Participants performed individualized PSSE-Schroth exercises based on curve pattern, including corrective breathing, postural correction, and ADL training

  • General ExercisesOther

    Participants performed general strengthening and stretching exercises without scoliosis-specific correction.

Study groups in NCT07552662
Study groupRoleWhat they receive
PSSE-Schroth GroupExperimentalParticipants performed individualized PSSE-Schroth exercises based on curve pattern, including corrective breathing, postural correction, and ADL training.
Receives: Other: PSSE-Schroth Exercises
General Exercise GroupActive comparatorParticipants performed general strengthening and stretching exercises without scoliosis-specific correction.
Receives: Other: General Exercises

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Change in Cobb Angle

    Cobb angle will be measured on standing anteroposterior spinal radiographs using the standard Cobb method. The angle is defined as the intersection of lines drawn parallel to the superior endplate of the upper-end vertebra and the inferior endplate of the lower-end vertebra of the primary curve. Measurements will be performed at baseline and after the intervention period, and the change in Cobb angle (in degrees) will be calculated. Lower values indicate an improvement in spinal curvature.

    Measured: Baseline to 12 Months

  2. Brace Prescription Rate

    The proportion of participants requiring orthotic bracing during the study period will be recorded. Brace prescription will be determined by a specialist according to established clinical criteria (e.g., curve magnitude, skeletal maturity, and risk of progression). The rate will be expressed as the percentage of participants prescribed a brace in each group during the follow-up period.

    Measured: 12 Months

Secondary outcomes (3)

  1. SRS-22 Questionnaire Score

    Health-related quality of life will be assessed using the Scoliosis Research Society-22 Questionnaire (SRS-22). This validated instrument includes five domains: function/activity, pain, self-image/appearance, mental health, and satisfaction with management. Each item is scored on a 5-point Likert scale, with higher scores indicating better health status. Assessments will be performed at baseline and after the intervention period, and changes in domain and total scores will be analyzed.

    Measured: Baseline to 12 Months

  2. TAPS Score

    Trunk appearance will be assessed using the Trunk Appearance Perception Scale (TAPS). This patient-reported outcome measure evaluates subjective perception of trunk deformity using a set of standardized drawings viewed from different perspectives. Each item is scored on a Likert scale, with higher scores indicating better perceived trunk appearance (less deformity). Assessments will be conducted at baseline and after the intervention period, and changes in TAPS scores will be analyzed.

    Measured: Baseline to 12 Months

  3. TRACE Score

    Clinical trunk deformity will be assessed using the Trunk Aesthetic Clinical Evaluation (TRACE) scale. This clinician-rated tool evaluates visible asymmetries of the shoulders, scapulae, waist, and hemithorax. Each domain is scored based on the severity of asymmetry, and a total score is calculated, with higher scores indicating greater aesthetic deformity. Assessments will be performed at baseline and after the intervention period, and changes in TRACE scores will be analyzed.

    Measured: Baseline to 12 Months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted27 Apr 2026
  2. Study start18 Apr 2024
  3. Primary completion18 Nov 2024
  4. Study completion18 Nov 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Model description
Participants were randomized in a 1:1 ratio to either PSSE-Schroth or General Exercise intervention.
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
32 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07552662
Sponsor's protocol ID
825/2
Status last verified
Apr 2024
First submitted
20 Apr 2026
Last updated
27 Apr 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Zhang Y, Chai T, Weng H, Liu Y. Pelvic rotation correction combined with Schroth exercises for pelvic and spinal deformities in mild adolescent idiopathic scoliosis: A randomized controlled trial. PLoS One. 2024 Jul 30;19(7):e0307955. doi: 10.1371/journal.pone.0307955. eCollection 2024.

    PubMed 39078854

  • Mohamed N, Acharya V, Schreiber S, Parent EC, Westover L. Effect of adding Schroth physiotherapeutic scoliosis specific exercises to standard care in adolescents with idiopathic scoliosis on posture assessed using surface topography: A secondary analysis of a Randomized Controlled Trial (RCT). PLoS One. 2024 Apr 30;19(4):e0302577. doi: 10.1371/journal.pone.0302577. eCollection 2024.

    PubMed 38687741

  • Kuru T, Yeldan I, Dereli EE, Ozdincler AR, Dikici F, Colak I. The efficacy of three-dimensional Schroth exercises in adolescent idiopathic scoliosis: a randomised controlled clinical trial. Clin Rehabil. 2016 Feb;30(2):181-90. doi: 10.1177/0269215515575745. Epub 2015 Mar 16.

    PubMed 25780260

  • Negrini S, Donzelli S, Aulisa AG, Czaprowski D, Schreiber S, de Mauroy JC, Diers H, Grivas TB, Knott P, Kotwicki T, Lebel A, Marti C, Maruyama T, O'Brien J, Price N, Parent E, Rigo M, Romano M, Stikeleather L, Wynne J, Zaina F. 2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth. Scoliosis Spinal Disord. 2018 Jan 10;13:3. doi: 10.1186/s13013-017-0145-8. eCollection 2018.

    PubMed 29435499

  • Weinstein SL, Dolan LA, Wright JG, Dobbs MB. Effects of bracing in adolescents with idiopathic scoliosis. N Engl J Med. 2013 Oct 17;369(16):1512-21. doi: 10.1056/NEJMoa1307337. Epub 2013 Sep 19.

    PubMed 24047455

  • Bago J, Sanchez-Raya J, Perez-Grueso FJ, Climent JM. The Trunk Appearance Perception Scale (TAPS): a new tool to evaluate subjective impression of trunk deformity in patients with idiopathic scoliosis. Scoliosis. 2010 Mar 25;5:6. doi: 10.1186/1748-7161-5-6.

    PubMed 20338048

  • Asher M, Min Lai S, Burton D, Manna B. The reliability and concurrent validity of the scoliosis research society-22 patient questionnaire for idiopathic scoliosis. Spine (Phila Pa 1976). 2003 Jan 1;28(1):63-9. doi: 10.1097/00007632-200301010-00015.

    PubMed 12544958

  • Langensiepen S, Semler O, Sobottke R, Fricke O, Franklin J, Schonau E, Eysel P. Measuring procedures to determine the Cobb angle in idiopathic scoliosis: a systematic review. Eur Spine J. 2013 Nov;22(11):2360-71. doi: 10.1007/s00586-013-2693-9. Epub 2013 Feb 27.

    PubMed 23443679

Questions about this trial

What is this clinical trial studying?

A study testing PSSE-Schroth Exercises and General Exercises in people with Scoliosis Idiopathic and Exercise, run by Hasan Kalyoncu University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 27 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change in Cobb Angle (time frame: Baseline to 12 Months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07552662, which also lists 8 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Apr 2026.

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