Postoperative PainNCT07558512
Risk Factors and a Predictive Nomogram for Acute Moderate-to-severe Postoperative Pain After Achilles Tendon Surgery
An observational study of Postoperative Pain, run by Min Li at 1 site in China.
Trial summary
This is a single-center retrospective cohort study to identify independent risk factors and develop a predictive nomogram for moderate-to-severe pain within 24 hours after Achilles tendon surgery. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Postoperative Pain
- What is being tested?
- No Study-Specific Intervention
- How many people
- 489 participants
- Where
- 1 siteChina
- Study dates
- 16 Apr 2026to 25 Apr 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The study population consists of adult patients (≥18 years) who underwent Achilles tendon surgery at Peking University Third Hospital between January 2020 and December 2024. Eligible patients were those with complete perioperative data and standardized 24-hour postoperative pain assessments, meeting all inclusion and exclusion criteria of the study.
Who may be able to join
- Age ≥ 18 years; American Society of Anesthesiologists (ASA) physical status classification Ⅰ~Ⅲ;
- Clinically diagnosed with Achilles tendon rupture, Achilles tendinopathy, insertional Achilles tendinitis, Haglund's deformity, or other Achilles tendon disorders;
- Undergoing open or arthroscopic Achilles tendon surgery;
- Conscious and able to cooperate in surgery and postoperative pain assessment;
- Complete and accessible case data related to surgery, anesthesia, and postoperative pain assessment;
- Completion of at least 24 hours of standardized pain monitoring and clinical follow-up after surgery
Who cannot join
- Missing or incomplete key clinical data such as pain assessment, surgery and anesthesia;
- Failure to complete 24-hour standardized pain monitoring after surgery; Perioperative unplanned secondary surgery or transfer to the intensive care unit (ICU);
- Patients with mental illness, cognitive dysfunction, or language communication barrier; History of alcohol or drug addiction Pain due to other acute or chronic diseases;
- Bilateral Achilles tendon surgery Concurrent surgery for other lower extremity injuries
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Risk Factors and a Predictive Nomogram for Acute Moderate-to-severe Postoperative Pain Afte Achilles Tendon Surgery: A Retrospective Cohort Study
This is a single-center retrospective cohort study to identify independent risk factors and develop a predictive nomogram for moderate-to-severe pain within 24 hours after Achilles tendon surgery.
- Conditions
- Postoperative Pain
- Being tested
- No Study-Specific Intervention
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No Study-Specific InterventionOther
This is a retrospective observational cohort study. No study-specific intervention is being investigated; all patients received routine clinical care as per standard practice.
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of Moderate-to-Severe Acute Postoperative Pain
Defined as a pain score ≥ 4 on the Numeric Rating Scale (NRS) or the need for rescue analgesia within the first 24 hours after Achilles tendon surgery. The NRS is an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain), where higher scores indicate greater pain severity (worse outcome).
Measured: Within 24 hours after surgery
Secondary outcomes (4)
Highest Postoperative Pain Score
The maximum pain score recorded within 24 hours after Achilles tendon surgery, measured using the Numeric Rating Scale (NRS). The NRS is an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain), where higher scores indicate greater pain severity (worse outcome).
Measured: Within 24 hours after surgery
Rescue Analgesia Requirement
Proportion of patients requiring rescue analgesic medications within 24 hours after surgery.
Measured: Within 24 hours after surgery
Incidence of Postoperative Nausea and Vomiting (PONV)
Proportion of patients experiencing nausea or vomiting requiring antiemetic treatment within 24 hours after surgery.
Measured: Within 24 hours after surgery
Postoperative Length of Hospital Stay
Number of days from surgery to hospital discharge.
Measured: From surgery to hospital discharge (up to 7 days)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Apr 2026
- Study start16 Apr 2026
- Primary completion25 Apr 2026
- Study completion25 Apr 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 489 participants (actual)
Sponsor and investigators
- Lead sponsor
- Min Li
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Min Li, Peking University Third Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07558512
- Sponsor's protocol ID
- M20260277
- Status last verified
- May 2026
- First submitted
- 23 Apr 2026
- Last updated
- 8 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Risk Factors and a Predictive Nomogram for Acute Moderate-to-severe Postoperative Pain Afte Achilles Tendon Surgery: A Retrospective Cohort Study
- ClinicalTrials.gov ID
- NCT07558512
- Acronym / sponsor ID
- M20260277
- Conditions
- Postoperative Pain
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 489 participants (actual)
- Lead sponsor
- Min LiUniversity, hospital or other
- Study start
- 16 Apr 2026 (actual)
- Primary completion
- 25 Apr 2026 (actual)
- Study completion
- 25 Apr 2026 (actual)
- First posted
- 30 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a single-center retrospective cohort study to identify independent risk factors and develop a predictive nomogram for moderate-to-severe pain within 24 hours after Achilles tendon surgery.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The study population consists of adult patients (≥18 years) who underwent Achilles tendon surgery at Peking University Third Hospital between January 2020 and December 2024. Eligible patients were those with complete perioperative data and standardized 24-hour postoperative pain assessments, meeting all inclusion and exclusion criteria of the study.
Key inclusion criteria (6 listed)
- Age ≥ 18 years; American Society of Anesthesiologists (ASA) physical status classification Ⅰ~Ⅲ;
- Clinically diagnosed with Achilles tendon rupture, Achilles tendinopathy, insertional Achilles tendinitis, Haglund's deformity, or other Achilles tendon disorders;
- Undergoing open or arthroscopic Achilles tendon surgery;
- Conscious and able to cooperate in surgery and postoperative pain assessment;
- Complete and accessible case data related to surgery, anesthesia, and postoperative pain assessment;
Key exclusion criteria (4 listed)
- Missing or incomplete key clinical data such as pain assessment, surgery and anesthesia;
- Failure to complete 24-hour standardized pain monitoring after surgery; Perioperative unplanned secondary surgery or transfer to the intensive care unit (ICU);
- Patients with mental illness, cognitive dysfunction, or language communication barrier; History of alcohol or drug addiction Pain due to other acute or chronic diseases;
- Bilateral Achilles tendon surgery Concurrent surgery for other lower extremity injuries
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No Study-Specific InterventionThis is a retrospective observational cohort study. No study-specific intervention is being investigated; all patients received routine clinical care as per standard practice. | Other | – |
Primary outcome
Incidence of Moderate-to-Severe Acute Postoperative Pain
Time frame: Within 24 hours after surgery
Defined as a pain score ≥ 4 on the Numeric Rating Scale (NRS) or the need for rescue analgesia within the first 24 hours after Achilles tendon surgery. The NRS is an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain), where higher scores indicate greater pain severity (worse outcome).
4 secondary outcomes
Highest Postoperative Pain Score
Time frame: Within 24 hours after surgery
Rescue Analgesia Requirement
Time frame: Within 24 hours after surgery
Incidence of Postoperative Nausea and Vomiting (PONV)
Time frame: Within 24 hours after surgery
Postoperative Length of Hospital Stay
Time frame: From surgery to hospital discharge (up to 7 days)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 May 2026.
Related trials for Postoperative Pain
RecruitingPhase 4
Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery
Laparoscopic Surgery, Visceral Pain, Postoperative
Recruiting
NOL Guided Analgesia During Elective Laparoscopic Surgery Under General Anesthesia
Intraoperative Analgesia
Recruiting
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
Postoperative Pain, Facial Swelling
Recruiting
Effect of Ultrasonic and Diode Laser Activated Irrigation on Postoperative Pain Following Root Canal Treatment
Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis
Not yet recruiting
Opioid Reduction and Enhanced Recovery in Orthopaedic Surgery (OREOS)-Knee
Knee Arthroplasty, Total, Partial Knee Arthroplasty
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Postoperative Pain, run by Min Li at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence of Moderate-to-Severe Acute Postoperative Pain (time frame: Within 24 hours after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 May 2026.