Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in ChildrenNCT07563400
Plaque Removal in Children Using Charcoal and Nylon Toothbrushes
A study testing soft charcoal infused bristle toothbrush (iLive) with bamboo handle and soft nylon bristle toothbrush (Oral B JUNIOR 6-12) in people with Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in Children, run by Cairo University.
Trial summary
This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush. We want to see which toothbrush is better at removing plaque and reducing bacteria in the mouth. Children will be randomly assigned to use one of the toothbrushes. Read more about this study
- Who is it for?
- Ages 6 to 10 yearsHealthy volunteers can take part
- Conditions the study is for
- Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in Children
- What is being tested?
- soft charcoal infused bristle toothbrush (iLive) with bamboo handle and soft nylon bristle toothbrush (Oral B JUNIOR 6-12)
- Type of treatment
- Pill or oral medicine, Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- Jun 2026to Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 10 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- ● Children aged 6 to 10 years.
- Medically free patients with no physical disability.
- Patients must have proper oral hygiene.
- Cooperative patients who will comply with follow-ups.
- Parents who accept to sign informed consent.
Who cannot join
- ● Children with a medical condition or physical disability,
- Children undergoing antibiotic treatment
- Children with crowding, fixed or removable orthodontic appliances.
- Children with pre-shedding mobile teeth were excluded from study.
- Children who will be unable to attend follow-up visits.
- Parents refuse to give written formed consent.
- Presence of painful teeth.
- Presence of active carious lesions
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Efficacy of Plaque Removal and Antibacterial Properties of Charcoal Infused Bristle Vs Nylon Bristle Toothbrushes in Children: A Randomized Clinical Trial
This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush. We want to see which toothbrush is better at removing plaque and reducing bacteria in the mouth. Children will be randomly assigned to use one of the toothbrushes. We will measure the levels of bacteria in small samples of fluid taken from the gums to see if one toothbrush reduces harmful bacteria more than the other.
Read the detailed description
This study is a clinical trial designed to compare the effectiveness of two types of toothbrushes in children aged 6-10. One group of children will use a toothbrush with charcoal-infused bristles, while the other group will use a standard nylon bristle toothbrush. All children will be taught the same brushing technique and will brush their teeth twice daily for two minutes using a pea-sized amount of toothpaste.The study will last two weeks. Researchers will measure four times how much dental plaque is removed from each child's teeth, collect samples from the gums to examine bacteria, and test the toothbrush bristles for bacterial contamination by counting bacterial colonies.The goal is to determine which toothbrush is better at cleaning teeth and reducing harmful bacteria in the mouth.
- Being tested
- soft charcoal infused bristle toothbrush (iLive) with bamboo handle, soft nylon bristle toothbrush (Oral B JUNIOR 6-12)
- Keywords
- charcoal toothbrush, antibacterial, bacterial contamination, gingival crevicular fluid, plaque removal, randomized clinical trial, nylon toothbrush
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
soft charcoal infused bristle toothbrush (iLive) with bamboo handleDevice
manual toothbrush with soft charcoal infused bristles designed fordaily oral hygiene measures. Participants will be instructed to brush twice daily for two minutes using herbal toothpaste
soft nylon bristle toothbrush (Oral B JUNIOR 6-12)Device
Manual toothbrush with soft nylon bristles designed for daily oral hygiene measures. Participants will be instructed to brush twice daily for two minutes using herbal toothpaste
| Study group | Role | What they receive |
|---|---|---|
| Charcoal-Infused Bristle Toothbrush | Experimental | Children in this arm will use a soft charcoal-infused bristle toothbrush twice daily for two minutes each time, using a pea-sized amount of fluoride-free toothpaste (Dabur Herb'l, India). Participants will be trained in the horizontal scrub technique and instructed on proper toothbrush storage to minimize bacterial contamination. Receives: Device: soft charcoal infused bristle toothbrush (iLive) with bamboo handle |
| Nylon Bristle Toothbrush | Active comparator | Children in this arm will use a soft nylon bristle toothbrush twice daily for two minutes each time, using a pea-sized amount of fluoride-free toothpaste Participants will be trained in the horizontal scrub technique and instructed on proper toothbrush storage to minimize bacterial contamination. Receives: Device: soft nylon bristle toothbrush (Oral B JUNIOR 6-12) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in full-mouth plaque score assessed by O'Leary Plaque Control Index from baseline to 2 weeks
Full-mouth plaque score will be measured using the O'Leary Plaque Control Index at four time points: baseline (before training), immediately after training, one week, and two weeks post-training. Each tooth surface (mesial, distal, buccal, and lingual) will be examined. The plaque score will be expressed as the percentage of plaque-containing surfaces relative to the total number of surfaces examined
Measured: aseline, immediately after training, 1 week, and 2 weeks post-training
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 May 2026
- Study startJun 2026 (estimated)
- Primary completionJul 2026 (estimated)
- Study completionAug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in ChildrenStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mennatullah Yasser Sayed Abou El Enein, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07563400
- Sponsor's protocol ID
- CU-PD-RCT-CHARCOAL-2026
- Status last verified
- Apr 2026
- First submitted
- 27 Apr 2026
- Last updated
- 4 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 4 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficacy of Plaque Removal and Antibacterial Properties of Charcoal Infused Bristle Vs Nylon Bristle Toothbrushes in Children: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07563400
- Acronym / sponsor ID
- CU-PD-RCT-CHARCOAL-2026
- Keywords
- charcoal toothbrush, antibacterial, bacterial contamination, gingival crevicular fluid, plaque removal, randomized clinical trial, nylon toothbrush
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- Jun 2026 (estimated)
- Primary completion
- Jul 2026 (estimated)
- Study completion
- Aug 2026 (estimated)
- First posted
- 4 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush. We want to see which toothbrush is better at removing plaque and reducing bacteria in the mouth. Children will be randomly assigned to use one of the toothbrushes. We will measure the levels of bacteria in small samples of fluid taken from the gums to see if one toothbrush reduces harmful bacteria more than the other.
Detailed description
This study is a clinical trial designed to compare the effectiveness of two types of toothbrushes in children aged 6-10. One group of children will use a toothbrush with charcoal-infused bristles, while the other group will use a standard nylon bristle toothbrush. All children will be taught the same brushing technique and will brush their teeth twice daily for two minutes using a pea-sized amount of toothpaste.The study will last two weeks. Researchers will measure four times how much dental plaque is removed from each child's teeth, collect samples from the gums to examine bacteria, and test the toothbrush bristles for bacterial contamination by counting bacterial colonies.The goal is to determine which toothbrush is better at cleaning teeth and reducing harmful bacteria in the mouth.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Charcoal-Infused Bristle Toothbrush | Experimental | Device: soft charcoal infused bristle toothbrush (iLive) with bamboo handleChildren in this arm will use a soft charcoal-infused bristle toothbrush twice daily for two minutes each time, using a pea-sized amount of fluoride-free toothpaste (Dabur Herb'l, India). Participants will be trained in the horizontal scrub technique and instructed on proper toothbrush storage to minimize bacterial contamination. |
| Nylon Bristle Toothbrush | Active comparator | Device: soft nylon bristle toothbrush (Oral B JUNIOR 6-12)Children in this arm will use a soft nylon bristle toothbrush twice daily for two minutes each time, using a pea-sized amount of fluoride-free toothpaste Participants will be trained in the horizontal scrub technique and instructed on proper toothbrush storage to minimize bacterial contamination. |
Who may qualify
- Ages
- 6 to 10 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (5 listed)
- ● Children aged 6 to 10 years.
Key exclusion criteria (8 listed)
- ● Children with a medical condition or physical disability,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| soft charcoal infused bristle toothbrush (iLive) with bamboo handlemanual toothbrush with soft charcoal infused bristles designed fordaily oral hygiene measures. Participants will be instructed to brush twice daily for two minutes using herbal toothpaste | Device | Charcoal-Infused Bristle Toothbrush |
| soft nylon bristle toothbrush (Oral B JUNIOR 6-12)Manual toothbrush with soft nylon bristles designed for daily oral hygiene measures. Participants will be instructed to brush twice daily for two minutes using herbal toothpaste | Device | Nylon Bristle Toothbrush |
Primary outcome
Change in full-mouth plaque score assessed by O'Leary Plaque Control Index from baseline to 2 weeks
Time frame: aseline, immediately after training, 1 week, and 2 weeks post-training
Full-mouth plaque score will be measured using the O'Leary Plaque Control Index at four time points: baseline (before training), immediately after training, one week, and two weeks post-training. Each tooth surface (mesial, distal, buccal, and lingual) will be examined. The plaque score will be expressed as the percentage of plaque-containing surfaces relative to the total number of surfaces examined
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 May 2026.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing soft charcoal infused bristle toothbrush (iLive) with bamboo handle and soft nylon bristle toothbrush (Oral B JUNIOR 6-12) in people with Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in Children, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 4 May 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mennatullah Y Abou El Enein (+201111184215, mennatullah.yasser@dentistry.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in full-mouth plaque score assessed by O'Leary Plaque Control Index from baseline to 2 weeks (time frame: aseline, immediately after training, 1 week, and 2 weeks post-training). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 May 2026; AzTrials last refreshed its copy on 6 Nov 2026.