Thirst; Due to Deprivation of WaterNCT07563530
Early Oral Hydration in Relieving Postoperative Thirst
A study testing Early oral hydration and No early oral hydration (As per Standard PACU Protocol) in people with Thirst; Due to Deprivation of Water and Patient Satisfaction, run by Sindh Institute of Urology and Transplantation at 1 site in Pakistan.
Trial summary
This study aims to evaluate whether allowing early oral hydration on demand effectively relieves postoperative thirst and enhances patient satisfaction in individuals undergoing urological endoscopic procedures Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Thirst; Due to Deprivation of Water, Patient Satisfaction
- What is being tested?
- Early oral hydration and No early oral hydration (As per Standard PACU Protocol)
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- 1 sitePakistan
- Study dates
- 18 Apr 2026to 18 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Male and female patients aged 18-65 years.
- Scheduled for elective urological endoscopic procedures under general anesthesia.
- Day-care endoscopic procedures.
- ASA classification I-III.
Who cannot join
- Known gastrointestinal disorders contraindicating early oral hydration (e.g., peptic ulcer disease, hiatal hernia, irritable bowel syndrome, esophagitis, or prior gastrointestinal surgery).
- Inability to express thirst or communicate (e.g., language barrier, altered consciousness).
- Requirement for nasogastric suction.
- History of facial, oropharyngeal, or laryngeal surgery.
- Swallowing dysfunction or delayed gastric emptying (e.g., gastroparesis).
- Incomplete reversal of muscle relaxant at PACU admission (no adequate spontaneous breathing or protective airway reflexes).
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Sindh Institute of Urology and Transplantation
Karachi, Sindh, 74200
Muhammad M Abbas, FCPS, +923331318838, smabbas69@hotmail.com
Love Khatri, IMM
About this study
Official title: Effectiveness of Early Oral Hydration in Relieving Postoperative Thirst in Patients Undergoing Urological Endoscopic Procedures: A Randomized Controlled Trial
This study aims to evaluate whether allowing early oral hydration on demand effectively relieves postoperative thirst and enhances patient satisfaction in individuals undergoing urological endoscopic procedures
Read the detailed description
Postoperative thirst is a frequent but often overlooked discomfort experienced by patients after surgery, particularly following urological endoscopic procedures.Despite the common restriction on carly oral intake due to concerns about nausea and aspiration, delaying hydration prolongs patient suffering and reduces satisfaction during recovery. This study aims to investigate whether allowing carly, on-demand oral hydration in the postanesthesia care unit (PACU) can effectively relieve postoperative thirst without increasing adverse effects, thereby potentially improving patient comfort and outcomes.
- Being tested
- Early oral hydration, No early oral hydration (As per Standard PACU Protocol)
- Keywords
- Postoperative, Thirst, Oral Hydration, Satisfaction
- Medical subject headings
- Patient Satisfaction, Personal Satisfaction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Early oral hydrationDietary supplement
"Early oral hydration" refers to the administration of small sips of water (maximum 10 mL initially) within 15-30 minutes of arrival in the PACU, once the patient is fully conscious, stable, and meets safety criteria.
Initially, patients will be provided a maximum of 10 mL of water using a straw. After this initial intake, they will be allowed to drink water according to their demand, provided their condition remains stable. To minimize the risk of adverse events such as regurgitation and aspiration, the total amount of water intake will be restricted to 0.5 mL/kg.
No early oral hydration (As per Standard PACU Protocol)Other
Patients in the control group will follow the standard PACU protocol, which will delay oral hydration for 2-3 hours after the end of anesthesia. During this period, patients will be monitored closely for thirst and other postoperative symptoms.
| Study group | Role | What they receive |
|---|---|---|
| EOH Group (Early Oral Hydration) | Experimental | Patients in the intervention group will be allowed early oral hydration on demand upon admission to the PACU if they meet the following safety criteria.
Practical PACU checklist to be fulfilled before giving plain water.
Require all of the following before any oral intake (start with small sips, e.g., 10 ml): Receives: Dietary Supplement: Early oral hydration |
| Control Group (Standard PACU Protocol) | Active comparator | Patients in the control group will follow the standard PACU protocol, which will delay oral hydration for 2-3 hours after the end of anesthesia. During this period, patients will be monitored closely for thirst and other postoperative symptoms. Receives: Other: No early oral hydration (As per Standard PACU Protocol) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Thirst intensity upon PACU arrival
Patients will be asked Did you experience thirst upon arrival in the PACU?
- Yes
- No If yes, rate your thirst intensity upon PACU arrival using the Visual Analogue Scale (VAS) on PACU entry. 0 = No thirst, 10 = Worst imaginable thirst [0---1---2---3---4---5---6---7---8---9---10]
Measured: Up to 2 hours during immediate post-operative period
Thirst intensity at PACU discharge
Patients will be asked Did you experience thirst at PACU discharge?
- Yes
- No If yes, rate your thirst intensity at PACU discharge using the VAS (0-10). 0 = No thirst, 10 = Worst imaginable thirst [0---1---2---3---4---5---6---7---8---9---10]
Measured: Up to 2 hours during immediate post-operative period
Patient comfort
Rate your comfort level during the PACU stay using the VAS (0-10) (0 = Uncomfortable, 10 = Very comfortable)
[0---1---2---3---4---5---6---7---8---9---10]
Measured: Up to 2 hours during immediate post-operative period
Patient satisfaction with the hydration timing.
How satisfied are you with the hydration timing? (5-point Likert Scale):
- Very Dissatisfied
- Dissatisfied
- Neutral
- Satisfied
- Very Satisfied
Measured: Up to 2 hours during immediate post-operative period
Patient satisfaction with the hydration procedure.
How satisfied are you with the hydration process overall? (5-point Likert Scale):
- Very Dissatisfied
- Dissatisfied
- Neutral
- Satisfied
- Very Satisfied
Measured: Up to 2 hours during immediate post-operative period
Total oral water intake (mL) during PACU stay.
The total amount of water intake will be restricted to 0.5 mL/kg. The water will be provided in a graduated cup, and the total water intake will be calculated as follows:
Total Water Intake (mL) = Volume of water in the cup upon PACU admission - Volume of water remaining in the cup upon PACU discharge.
Measured: Up to 2 hours iduring immediate post-operative period
Secondary outcomes (2)
Adverse Events
Do you experience any of the following adverse events after drinking water? (Check all that apply):
- Bucking
- Aspiration
- Vomiting
- None
Measured: Up to 2 hours during immediate post-operative period
Medical intervention given for any adverse event
Is medical intervention given for any adverse event?
- Yes (specify: _____________)
- No
Measured: Up to 2 hours during immediate post-operative period
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 May 2026
- Study start18 Apr 2026
- Primary completion18 Oct 2026 (estimated)
- Study completion18 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Thirst; Due to Deprivation of WaterStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- All eligible patients meeting the inclusion criteria will be identified preoperatively by the researcher. Written informed consent will be obtained from each participant after explaining the study purpose, procedures, possible risks, and benefits in their preferred language. Upon arrival in the PACU, patients will be randomized into Group A (early oral hydration) or Group B (control) is using sealed opaque envelopes.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sindh Institute of Urology and Transplantation
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Syed Muhammad Abbas, Sindh Institute of Urology and Transplantation
- Investigators
- Muhammad M Abbas, FCPS, Principal investigator, Sindh Institute of Urology and Transplantation
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07563530
- Sponsor's protocol ID
- SIUT-ERC-2025/A-586
- Status last verified
- Apr 2026
- First submitted
- 19 Apr 2026
- Last updated
- 4 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Early Oral Hydration in Relieving Postoperative Thirst in Patients Undergoing Urological Endoscopic Procedures: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07563530
- Acronym / sponsor ID
- SIUT-ERC-2025/A-586
- Keywords
- Postoperative, Thirst, Oral Hydration, Satisfaction
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Sindh Institute of Urology and TransplantationUniversity, hospital or other
- Study start
- 18 Apr 2026 (actual)
- Primary completion
- 18 Oct 2026 (estimated)
- Study completion
- 18 Oct 2026 (estimated)
- First posted
- 4 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate whether allowing early oral hydration on demand effectively relieves postoperative thirst and enhances patient satisfaction in individuals undergoing urological endoscopic procedures
Detailed description
Postoperative thirst is a frequent but often overlooked discomfort experienced by patients after surgery, particularly following urological endoscopic procedures.Despite the common restriction on carly oral intake due to concerns about nausea and aspiration, delaying hydration prolongs patient suffering and reduces satisfaction during recovery. This study aims to investigate whether allowing carly, on-demand oral hydration in the postanesthesia care unit (PACU) can effectively relieve postoperative thirst without increasing adverse effects, thereby potentially improving patient comfort and outcomes.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- All eligible patients meeting the inclusion criteria will be identified preoperatively by the researcher. Written informed consent will be obtained from each participant after explaining the study purpose, procedures, possible risks, and benefits in their preferred language. Upon arrival in the PACU, patients will be randomized into Group A (early oral hydration) or Group B (control) is using sealed opaque envelopes.
| Arm | Type | Receives |
|---|---|---|
| EOH Group (Early Oral Hydration) | Experimental | Dietary Supplement: Early oral hydrationPatients in the intervention group will be allowed early oral hydration on demand upon admission to the PACU if they meet the following safety criteria. Practical PACU checklist to be fulfilled before giving plain water. Require all of the following before any oral intake (start with small sips, e.g., 10 ml): |
| Control Group (Standard PACU Protocol) | Active comparator | Other: No early oral hydration (As per Standard PACU Protocol)Patients in the control group will follow the standard PACU protocol, which will delay oral hydration for 2-3 hours after the end of anesthesia. During this period, patients will be monitored closely for thirst and other postoperative symptoms. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Male and female patients aged 18-65 years.
- Scheduled for elective urological endoscopic procedures under general anesthesia.
- Day-care endoscopic procedures.
- ASA classification I-III.
Key exclusion criteria (6 listed)
- Known gastrointestinal disorders contraindicating early oral hydration (e.g., peptic ulcer disease, hiatal hernia, irritable bowel syndrome, esophagitis, or prior gastrointestinal surgery).
- Inability to express thirst or communicate (e.g., language barrier, altered consciousness).
- Requirement for nasogastric suction.
- History of facial, oropharyngeal, or laryngeal surgery.
- Swallowing dysfunction or delayed gastric emptying (e.g., gastroparesis).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Early oral hydration"Early oral hydration" refers to the administration of small sips of water (maximum 10 mL initially) within 15-30 minutes of arrival in the PACU, once the patient is fully conscious, stable, and meets safety criteria. Initially, patients will be provided a maximum of 10 mL of water using a straw. After this initial intake, they will be allowed to drink water according to their demand, provided their condition remains stable. To minimize the risk of adverse events such as regurgitation and aspiration, the total amount of water intake will be restricted to 0.5 mL/kg. | Dietary supplement | EOH Group (Early Oral Hydration) |
| No early oral hydration (As per Standard PACU Protocol)Patients in the control group will follow the standard PACU protocol, which will delay oral hydration for 2-3 hours after the end of anesthesia. During this period, patients will be monitored closely for thirst and other postoperative symptoms. | Other | Control Group (Standard PACU Protocol) |
Primary outcome
Thirst intensity upon PACU arrival
Time frame: Up to 2 hours during immediate post-operative period
Patients will be asked Did you experience thirst upon arrival in the PACU? * Yes * No If yes, rate your thirst intensity upon PACU arrival using the Visual Analogue Scale (VAS) on PACU entry. 0 = No thirst, 10 = Worst imaginable thirst [0---1---2---3---4---5---6---7---8---9---10]
Thirst intensity at PACU discharge
Time frame: Up to 2 hours during immediate post-operative period
Patients will be asked Did you experience thirst at PACU discharge? * Yes * No If yes, rate your thirst intensity at PACU discharge using the VAS (0-10). 0 = No thirst, 10 = Worst imaginable thirst [0---1---2---3---4---5---6---7---8---9---10]
Patient comfort
Time frame: Up to 2 hours during immediate post-operative period
Rate your comfort level during the PACU stay using the VAS (0-10) (0 = Uncomfortable, 10 = Very comfortable) [0---1---2---3---4---5---6---7---8---9---10]
Patient satisfaction with the hydration timing.
Time frame: Up to 2 hours during immediate post-operative period
How satisfied are you with the hydration timing? (5-point Likert Scale): * Very Dissatisfied * Dissatisfied * Neutral * Satisfied * Very Satisfied
Patient satisfaction with the hydration procedure.
Time frame: Up to 2 hours during immediate post-operative period
How satisfied are you with the hydration process overall? (5-point Likert Scale): * Very Dissatisfied * Dissatisfied * Neutral * Satisfied * Very Satisfied
Total oral water intake (mL) during PACU stay.
Time frame: Up to 2 hours iduring immediate post-operative period
The total amount of water intake will be restricted to 0.5 mL/kg. The water will be provided in a graduated cup, and the total water intake will be calculated as follows: Total Water Intake (mL) = Volume of water in the cup upon PACU admission - Volume of water remaining in the cup upon PACU discharge.
2 secondary outcomes
Adverse Events
Time frame: Up to 2 hours during immediate post-operative period
Medical intervention given for any adverse event
Time frame: Up to 2 hours during immediate post-operative period
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 May 2026.
Related trials for Thirst; Due to Deprivation of Water
Not yet recruiting
Effects of Habitual Water Intake on Thirst in Healthy Young Adults Explained by Osmoadaptive Metabolism, Brain and Kidney Function (Adapt-Thirst)
Chronic Underhydration, Thirst; Due to Deprivation of Water
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Muhammad M Abbas, FCPS principal investigator
Sindh Institute of Urology and Transplantation
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Early oral hydration and No early oral hydration (As per Standard PACU Protocol) in people with Thirst; Due to Deprivation of Water and Patient Satisfaction, run by Sindh Institute of Urology and Transplantation at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 4 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Muhammad M Abbas, FCPS (02199215718, smabbas69@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Thirst intensity upon PACU arrival (time frame: Up to 2 hours during immediate post-operative period). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 May 2026.