Colorectal CancerCoSMMONCT07569250
Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization
A study testing Personalized Text Message, Screening Concerns Text Message and Message Framing Text Message in people with Colorectal Cancer, run by University of Colorado, Denver at 4 sites in United States.
Trial summary
The goal of this interventional study is to create and test a comprehensive and low burden text message program within existing Community Health Centers (CHC) electronic records system to encourage patients to complete at home colorectal cancer (CRC) screening and to make sure they get follow-up care if their results… Read more about this study
- Who is it for?
- Ages 45 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Colorectal Cancer
- What is being tested?
- Personalized Text Message, Screening Concerns Text Message and Message Framing Text Message
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 7,220 participants
- Where
- 4 sitesUnited States
- Study dates
- Dec 2026to Jan 2032
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adults 45-75 years old
- Receive care in partner CHCs
- Are of average risk for colorectal cancer
- Received a stool-based testing order at their CHC
- Have a mobile phone and can receive text messages (Aim 1 quantitative cohort only)
- Fluent in English, Spanish, or another predominant language to be identified by the PI (applicable to patients focus groups cohort only)
Who cannot join
- Personal or family history of CRC or colorectal polyps
- History of inflammatory bowel disease
- Heritable conditions that put them at above average risk for colorectal cancer (e.g., familial adenomatous polyposis)
- Eligibility Criteria for CHC Staff Cohorts Inclusion Criteria (CHC Staff)
- Adult employees of participating CHCs
- Job responsibilities include activities related to CRC screening
- None
Trial locations and contacts
4 sites in 1 country. Contact the study team or a site near you to ask about taking part.
United States4 sites
The Massachusetts League of Community Health Center, Inc.
Boston, Massachusetts, 02108
Susan Dargon-Hart, LICSW, 617-877-6535, sdargonhart@massleague.org
Susan Dargon-Hart
Massachusetts General Hospital
Boston, Massachusetts, 02114
Stephanie Martinez, MPH, 617-643-4995, smartinez7@mgb.org
Adjoa Anyane-Yeboa, MD, MPH
Dana Farber Cancer Institute
Boston, Massachusetts, 02215
Soumya Mohanty, MBBS, MD, MPH, 857-263-9746, soumya_mohanty@dfci.harvard.edu
Kasisomayajula Viswanath, PhD
University of Texas Southwestern Medical Center
Dallas, Texas, 75390
Lynn N Ibekwe-Agunanna, PhD, MPH, 214-645-2532, Lynn.Ibekwe-Agunanna@utsouthwestern.edu
Lynn Ibekwe-Agunanna, MPH, PhD
About this study
The goal of this interventional study is to create and test a comprehensive and low burden text message program within existing Community Health Centers (CHC) electronic records system to encourage patients to complete at home colorectal cancer (CRC) screening and to make sure they get follow-up care if their results are abnormal.
First, the investigators will learn from clinic staff and patients what their needs and preferences are in terms of use of technology. This information will be used to design the text messages program.
Read more
- Clinic patients will participate in focus groups
- Clinic staff will participate in interviews
Second, the investigators will test a series of different message versions in two batches (experiments):
- Clinic patients with orders for an at-home colorectal cancer screening kit will receive the different message versions.
- In the first batch, the messages that get the most engagement from patients will be selected to be used in the second experiment.
- In the second batch, the investigators will test which messages lead to the most colorectal cancer screening completion.
- This will be rolled-out within the clinics existing electronic record system. The study team will not receive any information that will identify individual patients.
Lastly, the investigators will check again with clinic staff to learn how the program performed, and what would be needed to continue using the text message program in the long run.
-Clinic staff will participate in interviews and surveys.
Read the detailed description
This trial is studying optimization of text messages and outreach approaches by community health centers to increase patients' completion of FIT colon cancer screening tests. Text message reminders are a low cost, scalable way to deliver patient reminders that are low burden for staff. The proposed work uses a creative, community-engaged, systems-level approach to improve completion of FIT testing and abnormal follow-up and program sustainment in CHCs.
The study design includes three parts. First, the text messages will be optimized to maximize patient engagement and outreach (Aims 1 \& 2). The study will enroll patients from three partnering CHCs to participate in six focus groups to inform message design. The investigators will also conduct key informant interviews with 5-15 staff per CHC regarding the logistics of ensuring seamless integration into routine clinical operations and perspectives on the intervention activities. Then, a factorial experiment will be conducted, assigning 2,000 patients who have received a stool-based screening kit to different reminder messages. Engagement will be measured as replies or use of ≥1 links, to indicate interaction with the message. The experiment will compare: (1) personalization; (2) concern or negative emotions about screening; and (3) gain framing. In the factorial design patients will not be individually enrolled, this intervention will be tested within the workflows of usual practice. All data for the factorial experiment will be de-identified.
With those tools in place, the investigators will optimize outreach strategies for CRC screening completion. In a second factorial experiment with 5,100 patients, the investigators will optimize outreach strategy for primary screening outcomes of home-based stool screening test completion and screening completion by any guideline-recommended CRC screening test. Secondary outcomes include follow-up care for abnormal stool test results. In this factorial experiment, the investigators will test the impact of three outreach conditions on screening completion: increasing patient autonomy, providing information for accessing resources for impediments to care, and provision of live support. As in the first factorial test, for the second factorial test patients will not be individually enrolled, as the intervention will be tested within the workflows of usual practice. All data will be de-identified.
Finally, the study will assess implementation outcomes and sustainment of intervention components and effects. The investigators will conduct staff interviews and surveys to assess organizational capacity for sustaining the intervention elements being tested as well as the acceptability and feasibility of the text messages and screening tools. Sustainment of the text message outreach intervention elements will be assessed at post intervention and two 6-month intervals post-intervention.
- Conditions
- Colorectal Cancer
- Being tested
- Personalized Text Message, Screening Concerns Text Message, Message Framing Text Message, Autonomy Support Outreach, Impediments Support Outreach
- Keywords
- colorectal cancer screening, Text messaging, Community Health Centers (CHC)
- Medical subject headings
- Colorectal Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Personalized Text MessageBehavioural
Message includes personalized content.
Screening Concerns Text MessageBehavioural
Emotional concerns or barriers related to CRC screening.
Message Framing Text MessageBehavioural
Use gain-framed language to influence motivation.
Autonomy Support OutreachBehavioural
Provide patients with choices or options to increase sense of control.
Impediments Support OutreachBehavioural
Include information or resources to help overcome barriers to care.
Live Support OutreachBehavioural
Offer access to live assistance.
Data Reporting and Visualization System ToolsOther
Electronic alerts, dashboards, and tracking systems used to identify and follow up with patients due for CRC screening or abnormal results.
| Study group | Role | What they receive |
|---|---|---|
| Standard Message - Gain Frame | Experimental | No personalization, no concerns/negative emotion, gain-framed message. Receives: Behavioral: Message Framing Text Message; Other: Data Reporting and Visualization System Tools |
| Concern Message - Gain Frame | Experimental | No personalization, screening concerns/negative emotions, gain-framed message. Receives: Behavioral: Screening Concerns Text Message; Behavioral: Message Framing Text Message; Other: Data Reporting and Visualization System Tools |
| Concern Message - No Gain Frame | Experimental | No personalization, screening concerns/negative emotions, no gain-framed message. Receives: Behavioral: Screening Concerns Text Message; Behavioral: Message Framing Text Message; Other: Data Reporting and Visualization System Tools |
| Standard Message - No Gain Frame | Experimental | No personalization, no screening concerns/negative emotions, no gain-framed message. Receives: Behavioral: Message Framing Text Message; Other: Data Reporting and Visualization System Tools |
| Personalized Message - Gain Frame | Experimental | Personalization included, no screening concerns/negative emotions, gain-framed message. Receives: Behavioral: Personalized Text Message; Behavioral: Message Framing Text Message; Other: Data Reporting and Visualization System Tools |
| Personalized Message - No Gain Frame | Experimental | Personalization included, no screening concerns/negative emotions, no gain-framed message. Receives: Behavioral: Personalized Text Message; Behavioral: Message Framing Text Message; Other: Data Reporting and Visualization System Tools |
| Personalized - Concern Message - Gain Frame | Experimental | Personalization and screening concerns/negative emotions, gain framed message. Receives: Behavioral: Screening Concerns Text Message; Behavioral: Message Framing Text Message; Other: Data Reporting and Visualization System Tools |
| Personalized - Concern Message - No Gain Frame | Experimental | Personalization and screening concerns/negative emotions, no gain-framed message. Receives: Behavioral: Screening Concerns Text Message; Behavioral: Message Framing Text Message; Other: Data Reporting and Visualization System Tools |
| Basic Outreach Only | Experimental | No autonomy support, no impediments support, no live support. Receives: Behavioral: Live Support Outreach; Other: Data Reporting and Visualization System Tools |
| Outreach + Impediments Support | Experimental | No autonomy support, no live support. Impediment support. Receives: Behavioral: Impediments Support Outreach; Other: Data Reporting and Visualization System Tools |
| Outreach + Impediments + Live Support | Experimental | No autonomy support. Impediment support and live support included. Receives: Behavioral: Impediments Support Outreach; Behavioral: Live Support Outreach; Other: Data Reporting and Visualization System Tools |
| Outreach + Live Support | Experimental | Live support included. No autonomy or impediments support. Receives: Behavioral: Live Support Outreach; Other: Data Reporting and Visualization System Tools |
| Autonomy Outreach Support | Experimental | Autonomy support included, no impediments or live support. Receives: Behavioral: Autonomy Support Outreach; Other: Data Reporting and Visualization System Tools |
| Autonomy + Live Support | Experimental | Autonomy and live support with impediments support. Receives: Behavioral: Autonomy Support Outreach; Behavioral: Live Support Outreach; Other: Data Reporting and Visualization System Tools |
| Autonomy + Impediments Support | Experimental | Autonomy and impediments support included. No live support included. Receives: Behavioral: Autonomy Support Outreach; Behavioral: Impediments Support Outreach; Other: Data Reporting and Visualization System Tools |
| Autonomy + Impediments + Live Support | Experimental | Autonomy, impediments, and live support included. Receives: Behavioral: Autonomy Support Outreach; Behavioral: Impediments Support Outreach; Behavioral: Live Support Outreach; Other: Data Reporting and Visualization System Tools |
What is being measured
The primary outcome is the main question the study is designed to answer.
Text message engagement
Proportion of message recipients who interact with CRC screening reminder messages by reply
Measured: 14 days after reminder message delivery
Stool-based CRC screening completion
Proportion of message recipients with stool-based CRC screening tests resulted in electronic health record
Measured: 3 months after reminder message delivery
Secondary outcomes (2)
Time to follow-up care after abnormal stool-based screening test
Time (days) to follow-up care after abnormal stool-based screening test
Measured: 3 months after date of abnormal result
Invalid test results
Proportion of message recipients with invalid stool-based screening test result
Measured: 3 months after reminder message delivery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2026
- Study startDec 2026 (estimated)
- Primary completionOct 2031 (estimated)
- Study completionJan 2032 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Colorectal CancerStudies of the same condition, open and under way.
- More trials run by University of Colorado, DenverThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- None (open label)
- Enrolment
- 7,220 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Colorado, Denver
- Sponsor type
- University, hospital or other
- Collaborators
- National Institutes of Health (NIH), National Cancer Institute (NCI), Massachusetts League of Community Health Centers, Dana-Farber Cancer Institute, University of Texas Southwestern Medical Center, Massachusetts General Hospital
- Responsible party
- Sponsor
- Investigators
- Gina Kruse, MD, Principal investigator, University of Colorado, Denver
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07569250
- Sponsor's protocol ID
- 25-1144.cc
- Other IDs
- R01CA293501
- Acronym
- CoSMMO
- Status last verified
- Jul 2026
- First submitted
- 29 Apr 2026
- Last updated
- 10 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: All EHR derived data or data on text message intervention interactions, and any descriptive quality improvement data that we receive from the CHCs are de-identified. If qualitative data is shared, transcripts would be stripped of all identifiers.
Study at a glance
From the registry record, last updated by the sponsor on 10 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization
- ClinicalTrials.gov ID
- NCT07569250
- Acronym / sponsor ID
- CoSMMO / 25-1144.cc
- Conditions
- Colorectal Cancer
- Keywords
- colorectal cancer screening, Text messaging, Community Health Centers (CHC)
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 7,220 participants (estimated)
- Lead sponsor
- University of Colorado, DenverUniversity, hospital or other
- Collaborators
- National Institutes of Health (NIH), National Cancer Institute (NCI), Massachusetts League of Community Health Centers, Dana-Farber Cancer Institute, University of Texas Southwestern Medical Center, Massachusetts General Hospital
- Study start
- Dec 2026 (estimated)
- Primary completion
- Oct 2031 (estimated)
- Study completion
- Jan 2032 (estimated)
- First posted
- 6 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this interventional study is to create and test a comprehensive and low burden text message program within existing Community Health Centers (CHC) electronic records system to encourage patients to complete at home colorectal cancer (CRC) screening and to make sure they get follow-up care if their results are abnormal.
First, the investigators will learn from clinic staff and patients what their needs and preferences are in terms of use of technology. This information will be used to design the text messages program.
- Clinic patients will participate in focus groups
- Clinic staff will participate in interviews
Second, the investigators will test a series of different message versions in two batches (experiments):
- Clinic patients with orders for an at-home colorectal cancer screening kit will receive the different message versions.
- In the first batch, the messages that get the most engagement from patients will be selected to be used in the second experiment.
- In the second batch, the investigators will test which messages lead to the most colorectal cancer screening completion.
- This will be rolled-out within the clinics existing electronic record system. The study team will not receive any information that will identify individual patients.
Lastly, the investigators will check again with clinic staff to learn how the program performed, and what would be needed to continue using the text message program in the long run.
-Clinic staff will participate in interviews and surveys.
Detailed description
This trial is studying optimization of text messages and outreach approaches by community health centers to increase patients' completion of FIT colon cancer screening tests. Text message reminders are a low cost, scalable way to deliver patient reminders that are low burden for staff. The proposed work uses a creative, community-engaged, systems-level approach to improve completion of FIT testing and abnormal follow-up and program sustainment in CHCs.
The study design includes three parts. First, the text messages will be optimized to maximize patient engagement and outreach (Aims 1 \& 2). The study will enroll patients from three partnering CHCs to participate in six focus groups to inform message design. The investigators will also conduct key informant interviews with 5-15 staff per CHC regarding the logistics of ensuring seamless integration into routine clinical operations and perspectives on the intervention activities. Then, a factorial experiment will be conducted, assigning 2,000 patients who have received a stool-based screening kit to different reminder messages. Engagement will be measured as replies or use of ≥1 links, to indicate interaction with the message. The experiment will compare: (1) personalization; (2) concern or negative emotions about screening; and (3) gain framing. In the factorial design patients will not be individually enrolled, this intervention will be tested within the workflows of usual practice. All data for the factorial experiment will be de-identified.
With those tools in place, the investigators will optimize outreach strategies for CRC screening completion. In a second factorial experiment with 5,100 patients, the investigators will optimize outreach strategy for primary screening outcomes of home-based stool screening test completion and screening completion by any guideline-recommended CRC screening test. Secondary outcomes include follow-up care for abnormal stool test results. In this factorial experiment, the investigators will test the impact of three outreach conditions on screening completion: increasing patient autonomy, providing information for accessing resources for impediments to care, and provision of live support. As in the first factorial test, for the second factorial test patients will not be individually enrolled, as the intervention will be tested within the workflows of usual practice. All data will be de-identified.
Finally, the study will assess implementation outcomes and sustainment of intervention components and effects. The investigators will conduct staff interviews and surveys to assess organizational capacity for sustaining the intervention elements being tested as well as the acceptability and feasibility of the text messages and screening tools. Sustainment of the text message outreach intervention elements will be assessed at post intervention and two 6-month intervals post-intervention.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- None (open label)
- Number of arms
- 16
| Arm | Type | Receives |
|---|---|---|
| Standard Message - Gain Frame | Experimental | Behavioral: Message Framing Text Message, Other: Data Reporting and Visualization System ToolsNo personalization, no concerns/negative emotion, gain-framed message. |
| Concern Message - Gain Frame | Experimental | Behavioral: Screening Concerns Text Message, Behavioral: Message Framing Text Message, Other: Data Reporting and Visualization System ToolsNo personalization, screening concerns/negative emotions, gain-framed message. |
| Concern Message - No Gain Frame | Experimental | Behavioral: Screening Concerns Text Message, Behavioral: Message Framing Text Message, Other: Data Reporting and Visualization System ToolsNo personalization, screening concerns/negative emotions, no gain-framed message. |
| Standard Message - No Gain Frame | Experimental | Behavioral: Message Framing Text Message, Other: Data Reporting and Visualization System ToolsNo personalization, no screening concerns/negative emotions, no gain-framed message. |
| Personalized Message - Gain Frame | Experimental | Behavioral: Personalized Text Message, Behavioral: Message Framing Text Message, Other: Data Reporting and Visualization System ToolsPersonalization included, no screening concerns/negative emotions, gain-framed message. |
| Personalized Message - No Gain Frame | Experimental | Behavioral: Personalized Text Message, Behavioral: Message Framing Text Message, Other: Data Reporting and Visualization System ToolsPersonalization included, no screening concerns/negative emotions, no gain-framed message. |
| Personalized - Concern Message - Gain Frame | Experimental | Behavioral: Screening Concerns Text Message, Behavioral: Message Framing Text Message, Other: Data Reporting and Visualization System ToolsPersonalization and screening concerns/negative emotions, gain framed message. |
| Personalized - Concern Message - No Gain Frame | Experimental | Behavioral: Screening Concerns Text Message, Behavioral: Message Framing Text Message, Other: Data Reporting and Visualization System ToolsPersonalization and screening concerns/negative emotions, no gain-framed message. |
| Basic Outreach Only | Experimental | Behavioral: Live Support Outreach, Other: Data Reporting and Visualization System ToolsNo autonomy support, no impediments support, no live support. |
| Outreach + Impediments Support | Experimental | Behavioral: Impediments Support Outreach, Other: Data Reporting and Visualization System ToolsNo autonomy support, no live support. Impediment support. |
| Outreach + Impediments + Live Support | Experimental | Behavioral: Impediments Support Outreach, Behavioral: Live Support Outreach, Other: Data Reporting and Visualization System ToolsNo autonomy support. Impediment support and live support included. |
| Outreach + Live Support | Experimental | Behavioral: Live Support Outreach, Other: Data Reporting and Visualization System ToolsLive support included. No autonomy or impediments support. |
| Autonomy Outreach Support | Experimental | Behavioral: Autonomy Support Outreach, Other: Data Reporting and Visualization System ToolsAutonomy support included, no impediments or live support. |
| Autonomy + Live Support | Experimental | Behavioral: Autonomy Support Outreach, Behavioral: Live Support Outreach, Other: Data Reporting and Visualization System ToolsAutonomy and live support with impediments support. |
| Autonomy + Impediments Support | Experimental | Behavioral: Autonomy Support Outreach, Behavioral: Impediments Support Outreach, Other: Data Reporting and Visualization System ToolsAutonomy and impediments support included. No live support included. |
| Autonomy + Impediments + Live Support | Experimental | Behavioral: Autonomy Support Outreach, Behavioral: Impediments Support Outreach, Behavioral: Live Support Outreach, Other: Data Reporting and Visualization System ToolsAutonomy, impediments, and live support included. |
Who may qualify
- Ages
- 45 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Adults 45-75 years old
- Receive care in partner CHCs
- Are of average risk for colorectal cancer
- Received a stool-based testing order at their CHC
- Have a mobile phone and can receive text messages (Aim 1 quantitative cohort only)
Key exclusion criteria (7 listed)
- Personal or family history of CRC or colorectal polyps
- History of inflammatory bowel disease
- Heritable conditions that put them at above average risk for colorectal cancer (e.g., familial adenomatous polyposis)
- Eligibility Criteria for CHC Staff Cohorts Inclusion Criteria (CHC Staff)
- Adult employees of participating CHCs
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Personalized Text MessageMessage includes personalized content. | Behavioural | Personalized Message - Gain Frame, Personalized Message - No Gain Frame |
| Screening Concerns Text MessageEmotional concerns or barriers related to CRC screening. | Behavioural | Concern Message - Gain Frame, Concern Message - No Gain Frame, Personalized - Concern Message - Gain Frame, Personalized - Concern Message - No Gain Frame |
| Message Framing Text MessageUse gain-framed language to influence motivation. | Behavioural | Concern Message - Gain Frame, Concern Message - No Gain Frame, Personalized - Concern Message - Gain Frame, Personalized - Concern Message - No Gain Frame, Personalized Message - Gain Frame, Personalized Message - No Gain Frame, Standard Message - Gain Frame, Standard Message - No Gain Frame |
| Autonomy Support OutreachProvide patients with choices or options to increase sense of control. | Behavioural | Autonomy + Impediments + Live Support, Autonomy + Impediments Support, Autonomy + Live Support, Autonomy Outreach Support |
| Impediments Support OutreachInclude information or resources to help overcome barriers to care. | Behavioural | Autonomy + Impediments + Live Support, Autonomy + Impediments Support, Outreach + Impediments + Live Support, Outreach + Impediments Support |
| Live Support OutreachOffer access to live assistance. | Behavioural | Autonomy + Impediments + Live Support, Autonomy + Live Support, Basic Outreach Only, Outreach + Impediments + Live Support, Outreach + Live Support |
| Data Reporting and Visualization System ToolsElectronic alerts, dashboards, and tracking systems used to identify and follow up with patients due for CRC screening or abnormal results. | Other | Autonomy + Impediments + Live Support, Autonomy + Impediments Support, Autonomy + Live Support, Autonomy Outreach Support, Basic Outreach Only, Concern Message - Gain Frame, Concern Message - No Gain Frame, Outreach + Impediments + Live Support, Outreach + Impediments Support, Outreach + Live Support, Personalized - Concern Message - Gain Frame, Personalized - Concern Message - No Gain Frame, Personalized Message - Gain Frame, Personalized Message - No Gain Frame, Standard Message - Gain Frame, Standard Message - No Gain Frame |
Primary outcome
Text message engagement
Time frame: 14 days after reminder message delivery
Proportion of message recipients who interact with CRC screening reminder messages by reply
Stool-based CRC screening completion
Time frame: 3 months after reminder message delivery
Proportion of message recipients with stool-based CRC screening tests resulted in electronic health record
2 secondary outcomes
Time to follow-up care after abnormal stool-based screening test
Time frame: 3 months after date of abnormal result
Invalid test results
Time frame: 3 months after reminder message delivery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Jul 2026.
- Individual participant dataSharing planned: Yes. All EHR derived data or data on text message intervention interactions, and any descriptive quality improvement data that we receive from the CHCs are de-identified. If qualitative data is shared, transcripts would be stripped of all identifiers.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Gina Kruse, MD principal investigator
University of Colorado, Denver
4 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Personalized Text Message, Screening Concerns Text Message and Message Framing Text Message in people with Colorectal Cancer, run by University of Colorado, Denver at 4 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 10 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Yamila Sierra (303-724-4811, yamila.sierra@cuanschutz.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Text message engagement (time frame: 14 days after reminder message delivery). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Jul 2026.