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Brain Tumor AdultAPATCNCT07570485

Feasibility Assessment of Adapted Physical Activity in Patients Treated for a Brain Tumor

A study testing adapted physical activity in people with Brain Tumor Adult, run by Center Eugene Marquis at 1 site in France.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

The goal of this clinical trial is to assess the feasibility of an adapted physical activity (APA) program in adult patients (≥18 years) with primary brain tumors, regardless of tumor type, grade, treatment stage, or the presence of motor, sensory, attention, concentration, or memory deficits. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Brain Tumor Adult
What is being tested?
adapted physical activity
Could I receive a placebo?
No, everyone receives an active treatment
How many people
90 participants
Where
1 siteFrance
Study dates
8 Jul 2026to 1 Jun 2028
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Men or women ≥ 18 years old,
  • Receiving medical oncology treatment at the CLCC Eugène Marquis,
  • Diagnosed with a primary brain tumour, regardless of diagnosis, grade or treatment,
  • Possible motor, sensory, attention, concentration, or memory deficits,
  • Patients who accept the general terms of use for connected watches
  • Patients affiliated with or covered by the French social security system,
  • Patients who have received information and signed informed consent (or their legal representative),

Who cannot join

  • WHO score ≥ 3
  • Comprehension disorders that prevent participation in adapted physical activity
  • Pregnant or breastfeeding women
  • Patients without the necessary devices to use a smartwatch (smartphone, tablet or computer),
  • Patients deprived of liberty, under guardianship, or curatorship, or subject to any other administrative safeguard measure.
  • Patients unable to comply with the study schedule for social, medical, or psychological reasons.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Valérie JOLAINE contact

0299253036

v.jolaine@rennes.unicancer.fr

France1 site, 1 recruiting

  • Centre Eugène Marquis

    Rennes, 35000

    Valérie JOLAINE, 0299253036, v.jolaine@rennes.unicancer.fr

    Elodie VAULEON, DR

    Recruiting

Other trials in France

About this study

The goal of this clinical trial is to assess the feasibility of an adapted physical activity (APA) program in adult patients (≥18 years) with primary brain tumors, regardless of tumor type, grade, treatment stage, or the presence of motor, sensory, attention, concentration, or memory deficits.

The main question it aims to answer is:

Read more

What is the effective adherence rate to an APA program among eligible patients with primary brain tumors?

Additional questions include:

  • What is the observance rate (number of sessions completed, intensity achieved, and duration) during the 3-month supervised APA program?
  • What is the retention rate (proportion of patients completing the program and continuing APA beyond the initial period)?
  • What is the impact of APA on quality of life, anxiety-depression, and cancer-related symptoms (measured via QLQ-BN20, HADS, and MFI-20 questionnaires at baseline, 3, and 4 months)?

Participants will:

  • Undergo a 3-month supervised APA program (with possible continuation beyond this period).
  • Use connected watches to monitor physical activity (if they accept the general conditions of use).
  • Complete self-questionnaires (IPAQ, BREQ-2, QPP, QLQ-BN20, HADS, MFI-20) at inclusion, 3 months, and 4 months.
  • Be followed for a total of 4 months after inclusion.
Being tested
adapted physical activity
Keywords
Brain Tumor, Adapted physical activity (APA)
Medical subject headings
Brain Neoplasms

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • adapted physical activityOther

    Adapted Physical Activity (APA) is a tailored exercise program designed for individuals with specific health conditions, such as brain tumors. It aims to improve physical function, quality of life, and overall well-being while ensuring safety and feasibility. APA is supervised by trained professionals and adapted to each individual's abilities and needs.

Study groups in NCT07570485
Study groupRoleWhat they receive
PA with Strength Sheets + Walking RecommendationExperimentalPatients receive 2 strength exercise sheets to perform weekly at home + a recommendation to walk regularly (30 min/day). No supervised sessions. Activity is self-monitored via connected watch.
Receives: Other: adapted physical activity
APA with Strength Sheet + Group Videoconference SessionExperimentalPatients receive 1 strength exercise sheet to perform weekly at home + 1 hour of group training via videoconference per week. The videoconference session content matches the 2nd strength sheet from Arm 1. Activity is self-monitored via connected watch.
Receives: Other: adapted physical activity
APA with Strength Sheet + Individual Home SessionExperimentalPatients receive 1 strength exercise sheet to perform weekly at home + 1 hour of individualized and personalized training at home per week. The home session content matches the 2nd strength sheet from Arm 1. Activity is self-monitored via connected watch.
Receives: Other: adapted physical activity

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Effective adherence rate to the Adapted Physical Activity program

    The primary outcome is the proportion of eligible patients who participate in at least one Adapted Physical Activity session out of the total number of eligible patients solicited for inclusion. This metric Evaluates the feasibility of Adapted Physical Activity implementation in brain tumor patients.

    Measured: Baseline to 4 months

Secondary outcomes (10)

  1. Adapted Physical Activity program observance rate

    Evaluated through the number of sessions completed, the number of sessions reaching the recommended intensity level, and the duration of sessions performed during the 3-month supervised period and the 1-month autonomous period.

    Measured: Baseline to 4 months

  2. Retention rate during the 3-month supervised Adapted Physical Activity period

    Proportion of patients who complete the entire 3-month supervised APA program, reflecting their commitment and ability to sustain participation.

    Measured: Baseline to 3 months

  3. Retention Rate After Supervised Adapted Physical Activity Period

    Proportion of patients who continue Adapted Physical Activity beyond the initial 3-month supervised period, assessed at 4 months.

    Measured: 4 months

  4. Reasons for early discontinuation of Adapted Physical Activity

    Documentation of specific reasons (e.g., fatigue, disease progression, lack of motivation) for patients who discontinue Adapted Physical Activity prematurely

    Measured: Baseline to 4 months

  5. Quality of life assessment using EORTC Quality of Life Questionnaire - Brain Neoplasm Module 20. Minimum value = 0, maximum value = 100. A higher score mean a worse outcome.

    Evaluation of brain tumor-specific quality of life using the EORTC Quality of Life Questionnaire - Brain Neoplasm Module 20 questionnaire, which assesses symptoms and functional domains relevant to brain tumor patients

    Measured: Baseline, 3 months, and 4 months

  6. Anxiety and depression assessment using Hospital Anxiety and Depression Scale questionnaire

    Evaluation of anxiety and depression levels using the Hospital Anxiety and Depression Scale, a validated tool for assessing psychological distress. Minimum value = 0, maximum value = 21. A higher score mean a worse outcome.

    Measured: Baseline, 3 months, and 4 months

  7. Fatigue assessment using Multidimensional Fatigue Inventory-20 questionnaire

    Evaluation of multidimensional fatigue (general, physical, mental, reduced motivation, and reduced activity) using the Multidimensional Fatigue Inventory-20 questionnaire. Minimum value = 4, maximum value = 20. The higher the score, the greater the fatigue.

    Measured: Baseline, 3 months, and 4 months

  8. Physical activity level assessment using International Physical Activity Questionnaire

    Evaluation of physical activity intensity and frequency using the International Physical Activity Questionnaire, which classifies participants into low, moderate, or high activity levels. The higher the score, the higher the calculated energy expenditure.

    Measured: Baseline, 3 months, and 4 months

  9. Motivation for physical activity assessment using Behavioral Regulation in Exercise Questionnaire - Version 2

    Evaluation of motivation types (intrinsic, identified, introjected, external) using the Behavioral Regulation in Exercise Questionnaire - Version 2

    Measured: Baseline, 3 months, and 4 months

  10. Perceived enjoyment of physical activity assessment using Physical Activity Enjoyment Scale questionnaire

    Evaluation of enjoyment and satisfaction related to physical activity using the Physical Activity Enjoyment Scale questionnaire. Scoring range : 18 to 126 where higher scores indicate greater perceived enjoyment.

    Measured: Baseline, 3 months, and 4 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted6 May 2026
  2. Study start8 Jul 2026
  3. Primary completion1 Jun 2028 (estimated)
  4. Study completion1 Jun 2028 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Non-randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
90 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07570485
Sponsor's protocol ID
2025-4-79-002
Acronym
APATC
Status last verified
Oct 2026
First submitted
30 Apr 2026
Last updated
26 Oct 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Questions about this trial

What is this clinical trial studying?

A study testing adapted physical activity in people with Brain Tumor Adult, run by Center Eugene Marquis at 1 site in France.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 26 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Valérie JOLAINE (0299253036, v.jolaine@rennes.unicancer.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Effective adherence rate to the Adapted Physical Activity program (time frame: Baseline to 4 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07570485.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Oct 2026.

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