Tobacco-Related CarcinomaNCT07571018
A Novel Mobile Health Intervention for Improving Tobacco Cessation Among Young Adults
A study testing Smartphone app-based Intervention, Communication intervention and Survey Administration in people with Tobacco-Related Carcinoma, run by Fred Hutchinson Cancer Center at 2 sites in United States.
Trial summary
Tobacco use is the leading cause of preventable cancer deaths. Among young adults, approximately 1 in 5 use commercial nicotine and tobacco products, putting them at risk of developing nicotine addiction and long-term health effects from exposure to toxicants. Read more about this study
- Who is it for?
- Ages 18 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Tobacco-Related Carcinoma
- What is being tested?
- Smartphone app-based Intervention, Communication intervention and Survey Administration
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 6 participants
- Where
- 2 sitesUnited States
- Study dates
- 7 Jun 2026to 11 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-identify being between 18 and 30 years of age
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must be a United States (US) resident, with a US mailing address
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-report use of any (non-therapeutic) nicotine or tobacco product at least once per week in the 30 days prior to screening
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must own a smartphone
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-report having internet access for the interviews
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-report that they are interested in participating in the study for themselves (versus [vs] someone else)
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- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-report that they have not participated in one of our prior tobacco cessation studies
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-report that they understand and agree to the conditions of compensation
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-report that they are not currently incarcerated
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must be willing and able to complete study procedures in English
- PILOT TRIAL: Participants must self-identify being between 18 and 30 years of age
- PILOT TRIAL: Participants must currently reside in the US and anticipate continued residence for the duration of the study (3 months)
- PILOT TRIAL: Participants must self-report use of any (non-therapeutic) nicotine or tobacco product at least once per week in the 30 days prior to screening
- PILOT TRIAL: Participants must own an Android (running version 12 or higher) or iPhone (running iOS version 17 or higher, iPhone 11 or more recent)
- PILOT TRIAL: Participants must self-report having at least weekly internet access for the next three months
- PILOT TRIAL: Participants must be willing and able to download an app to their phone and receive text messages
- PILOT TRIAL: Participants must self-report current use of a personal email account
- PILOT TRIAL: Participants must self-report current use of text messaging
- PILOT TRIAL: Participants must self-report that they are interested in participating in the study for themselves (vs someone else)
- PILOT TRIAL: Participants must self-report that they have not participated in one of our prior tobacco cessation studies
- PILOT TRIAL: Participants must self-report that they understand and agree to the conditions of compensation
- PILOT TRIAL: Participants must self-report that they are not currently incarcerated
- PILOT TRIAL: Participants must be willing to use the assigned intervention program, complete the study assessments, and complete an online consent form in English
- POST PILOT TRIAL DIARY STUDY: Participants must self-identify being between 18 and 30 years of age
- POST PILOT TRIAL DIARY STUDY: Participants must currently reside in the US
- POST PILOT TRIAL DIARY STUDY: Participants must self-report use of any (non-therapeutic) nicotine or tobacco product at least once per week in the 30 days prior to screening
- POST PILOT TRIAL DIARY STUDY: Participants must own an Android (running version 12 or higher) or iPhone (running iOS version 17 or higher, iPhone 11 or more recent)
- POST PILOT TRIAL DIARY STUDY: Participants must self-report having at least internet access for the duration of the diary study
- POST PILOT TRIAL DIARY STUDY: Participants must be willing and able to download an app to their phone and receive text messages
- POST PILOT TRIAL DIARY STUDY: Participants must self-report current use of a personal email account
- POST PILOT TRIAL DIARY STUDY: Participants must self-report current use of text messaging
- POST PILOT TRIAL DIARY STUDY: Participants must self-report that they are interested in participating in the study for themselves (vs someone else)
- POST PILOT TRIAL DIARY STUDY: Participants must self-report that they have not participated in one of our prior tobacco cessation studies
- POST PILOT TRIAL DIARY STUDY: Participants must self-report that they understand and agree to the conditions of compensation
- POST PILOT TRIAL DIARY STUDY: Participants must self-report that they are not currently incarcerated
- POST PILOT TRIAL DIARY STUDY: Participants must be willing to use the intervention program, complete the study assessments, and complete an online consent form in English
Who cannot join
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Individuals must not be < 18 or > 30 years of age
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Individuals must not have a Google voice number as their sole phone number
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Individuals who are non-English speaking cannot participate, as this would prevent their participation in the interviews, which will be conducted in English
- PILOT TRIAL: Participants must not be < 18 or > 30 years of age
- PILOT TRIAL: Participants must not be currently using other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (but initiating these treatments during the study is allowed)
- PILOT TRIAL: Participants must not be a member of the same household as another research participant
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- PILOT TRIAL: Participants must not have a Google voice number as their sole phone number
- PILOT TRIAL: Participants must not be identified as fraudulent per our fraud prevention protocol
- PILOT TRIAL: Participants must not be pregnant or plan on becoming pregnant over the next 3 months
- POST PILOT TRIAL DIARY STUDY: Individuals must not be < 18 or > 30 years of age
- POST PILOT TRIAL DIARY STUDY: Participants must not have a Google voice number as their sole phone number
- POST PILOT TRIAL DIARY STUDY: Individuals who are non-English speaking cannot participate, as this would prevent their participation in the interviews, which will be conducted in English
Trial locations and contacts
2 sites in 1 country.
United States2 sites
New Mexico State University
Las Cruces, New Mexico, 88003
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109
About this study
Official title: Development and Pilot Evaluation of a Novel Mobile Health Intervention for Young Adult Tobacco Cessation
Tobacco use is the leading cause of preventable cancer deaths. Among young adults, approximately 1 in 5 use commercial nicotine and tobacco products, putting them at risk of developing nicotine addiction and long-term health effects from exposure to toxicants. Innovative approaches are needed to engage young adults in treatment, as they are less engaged in traditional treatment.
This clinical trial compares two versions of a mobile health intervention called Living Free from Tobacco (LiFT), designed to support nicotine and tobacco cessation among young adults. Both versions of the app are designed to motivate and support young adults to stop using nicotine and tobacco, regardless of current readiness to quit. Version A of the LiFT app (LiFT A) focuses on increasing psychological flexibility to support cessation, while Version B (LiFT B) provides educational content and resources related to tobacco use and cessation. Both versions of the program are delivered through a smartphone application and include accompanying text messages.
Read the detailed description
OUTLINE: Participants are assigned to 1 of 3 phases.
USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT PHASE (Objective 1): Participants attend user testing interviews where they interact with LiFT application (app) prototypes and provide feedback through think-aloud methods to support refinement of the intervention content and features.
PILOT TRIAL PHASE (Objective 2): Participants are randomized to 1 of 2 arms.
- ARM I: Participants use the LiFT A app, which includes interactive games and exercises, educational content, and tools tailored to young adults using an acceptance and commitment therapy (ACT) treatment approach, for 3 months. Participants also receive associated text messages 2-3 times per week.
- ARM II: Participants use the LiFT B app, which includes educational resources on preparing to quit, nicotine withdrawal, coping with withdrawal, and mental health, along with health information videos, for 3 months. Participants also receive associated text messages 2-3 times per week.
POST PILOT TRIAL DIARY STUDY PHASE (Objective 3): Participants use the LiFT app and complete daily usability and satisfaction assessments for approximately 1 week. Participants also complete a survey and attend an interview.
- Conditions
- Tobacco-Related Carcinoma
- Being tested
- Smartphone app-based Intervention, Communication intervention, Survey Administration, Interview, Assessment
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Smartphone app-based InterventionOther
Use LiFT A app
Smartphone app-based InterventionOther
Use LiFT B app
Communication interventionOther
Receive LiFT A text messages
Communication interventionOther
Receive LiFT B text messages
Survey AdministrationOther
Complete surveys
InterviewOther
Attend interview
AssessmentOther
Complete usability assessment
Survey AdministrationOther
Complete survey
| Study group | Role | What they receive |
|---|---|---|
| User-centered design and program development phase (interview) [Objective 1] | No intervention | Participants attend user testing interviews where they interact with LiFT app prototypes and provide feedback through think-aloud methods to support refinement of the intervention content and features. |
| Pilot phase, Arm I (LiFT A app, LiFT A text messages) [Objective 2] | Experimental | Participants use the LiFT A app, which includes interactive games and exercises, educational content, and tools tailored to young adults using an ACT treatment approach, for 3 months. Participants also receive LiFT A text messages 2-3 times per week. Receives: Other: Smartphone app-based Intervention; Other: Communication intervention; Other: Survey Administration |
| Pilot phase, Arm II (LiFT B app, LiFT B text messages) [Objective 2] | Experimental | Participants use the LiFT B app, which includes educational resources on preparing to quit, nicotine withdrawal, coping with withdrawal, mental health, along with health information videos, for 3 months. Participants also receive LiFT B text messages 2-3 times per week. Receives: Other: Smartphone app-based Intervention; Other: Communication intervention; Other: Survey Administration |
| Post pilot trial diary study phase (LiFT, survey, interview) [Objective 3] | Other | Participants use the LiFT app and complete daily usability and satisfaction assessments for approximately 1 week. Participants also complete a survey and attend an interview. Receives: Other: Smartphone app-based Intervention; Other: Interview; Other: Assessment; Other: Survey Administration |
What is being measured
The primary outcome is the main question the study is designed to answer.
Overall satisfaction (Pilot trial phase)
Overall satisfaction with the assigned program will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Measured: At 3 months
Number of logins to assigned application (Pilot trial phase)
Treatment utilization will include number of logins to the assigned application, determined objectively using tracking software.
Measured: At 3 months
Usefulness of the program (Pilot trial phase)
The perceived usefulness of the assigned program will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Measured: At 3 months
Usefulness of text messages (Pilot trial phase)
The perceived usefulness of the assigned program's text messages will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Measured: At 3 months
Satisfaction with perceived tailoring (Pilot trial phase)
The perception that the assigned program was made for someone like the participant will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Measured: At 3 months
Satisfaction with guidance on how to quit (Pilot trial phase)
The perception that the program clarified how to quit nicotine/tobacco when ready will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Measured: At 3 months
Perception that program offered a novel approach to quitting (Pilot trial phase)
The perception that the program offered a new way of looking at quitting will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Measured: At 3 months
Perceived helpfulness for quit preparation (Pilot trial phase)
The perception that the program will help with quitting if/when ready will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Measured: At 3 months
Willingness to recommend program to a friend (Pilot trial phase)
Whether the respondent would recommend the program to a friend will be assessed via responses of "yes," "no," or "not sure." Responses will be categorized into a binary variable representing "yes" versus other responses (i.e.,"no" or "not sure").
Measured: At 3 months
Usability (Post pilot trial diary study phase)
Qualitative data from interviews, diary entries and exit interviews will be coded and analyzed using rapid inductive content analysis to extract themes. Usability data will be reported using descriptive statistics and compared against the benchmark score of 68, which represents average usability.
Measured: At completion of post pilot trial diary study phase (At Day 9)
Secondary outcomes (8)
Biochemically-confirmed 7-day point prevalence abstinence (PPA) from all nicotine and tobacco use (Pilot trial phase)
Percentage of participants reporting abstinence from all nicotine and tobacco use (excluding Food and Drug Administration-approved pharmacotherapies) over the previous 7 days, biochemically confirmed via saliva cotinine.
Measured: At 3 months
Self-reported 7-day PPA from all nicotine and tobacco use (Pilot trial phase)
Percentage of participants reporting abstinence from all nicotine and tobacco use (excluding Food and Drug Administration-approved pharmacotherapies) over the previous 7 days.
Measured: At 3 months
Self-reported 30-day PPA (Pilot trial phase)
Percentage of participants reporting abstinence from all nicotine and tobacco use (excluding Food and Drug Administration-approved pharmacotherapies) over the previous 30 days.
Measured: At 3 months
Cotinine-confirmed 30-day PPA (Pilot trial phase)
Percentage of participants reporting abstinence from all nicotine and tobacco use (excluding Food and Drug Administration-approved pharmacotherapies) over the previous 30 days, biochemically confirmed via saliva cotinine.
Measured: At 3 months
Average change in Contemplation Ladder scores (Pilot trial phase)
The outcome will be calculated as the 3-month follow-up minus baseline score on the 11-point Contemplation Ladder. Positive change scores indicate increases in readiness to quit, on average, whereas negative change scores indicate decreases in readiness to quit.
Measured: From baseline to 3 months
Change in acceptance of tobacco use triggers (Pilot trial phase)
This outcome will be calculated as the 3-month follow-up minus baseline score on the cravings subscale of the Avoidance and Inflexibility Scale. Because avoidance and inflexibility represent the inverse of acceptance, positive change scores indicate a decrease in acceptance, on average, whereas negative change scores indicate increased acceptance of tobacco use triggers.
Measured: From baseline to 3 months
Change in values progress (Pilot trial phase)
This outcome will be calculated as the 3-month follow-up minus baseline score the progress subscale of the Valuing Questionnaire. Positive change scores indicate increases in values progress, on average, whereas negative change scores indicate decreases in values progress.
Measured: From baseline to 3 months
Change in values obstruction (Pilot trial phase)
This outcome will be calculated as the 3-month follow-up minus baseline score the values obstruction subscale of the Valuing Questionnaire. Positive change scores indicate increases in values obstruction, on average, whereas negative change scores indicate decreases in values obstruction.
Measured: From baseline to 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2026
- Study start7 Jun 2026
- Primary completion11 Jun 2026
- Study completion11 Jun 2026
Why it stopped: Discontinuation of funding
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tobacco-Related CarcinomaStudies of the same condition, open and under way.
- More trials run by Fred Hutchinson Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- PILOT TRIAL: Parallel; USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: N/A; POST PILOT TRIAL DIARY STUDY: N/A
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 6 participants (actual)
Sponsor and investigators
- Lead sponsor
- Fred Hutchinson Cancer Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Responsible party
- Sponsor
- Investigators
- Jaimee Heffner, PhD, Principal investigator, Fred Hutch/University of Washington Cancer Consortium
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07571018
- Sponsor's protocol ID
- RG1126140
- Other IDs
- NCI-2026-00801, U54CA132381
- Status last verified
- Oct 2026
- First submitted
- 30 Apr 2026
- Last updated
- 16 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Development and Pilot Evaluation of a Novel Mobile Health Intervention for Young Adult Tobacco Cessation
- ClinicalTrials.gov ID
- NCT07571018
- Acronym / sponsor ID
- RG1126140
- Conditions
- Tobacco-Related Carcinoma
- Study type
- Interventional
- Recruitment status
- TerminatedReason stopped: Discontinuation of funding
- Enrolment
- 6 participants (actual)
- Lead sponsor
- Fred Hutchinson Cancer CenterUniversity, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Study start
- 7 Jun 2026 (actual)
- Primary completion
- 11 Jun 2026 (actual)
- Study completion
- 11 Jun 2026 (actual)
- First posted
- 6 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Tobacco use is the leading cause of preventable cancer deaths. Among young adults, approximately 1 in 5 use commercial nicotine and tobacco products, putting them at risk of developing nicotine addiction and long-term health effects from exposure to toxicants. Innovative approaches are needed to engage young adults in treatment, as they are less engaged in traditional treatment.
This clinical trial compares two versions of a mobile health intervention called Living Free from Tobacco (LiFT), designed to support nicotine and tobacco cessation among young adults. Both versions of the app are designed to motivate and support young adults to stop using nicotine and tobacco, regardless of current readiness to quit. Version A of the LiFT app (LiFT A) focuses on increasing psychological flexibility to support cessation, while Version B (LiFT B) provides educational content and resources related to tobacco use and cessation. Both versions of the program are delivered through a smartphone application and include accompanying text messages.
Detailed description
OUTLINE: Participants are assigned to 1 of 3 phases.
USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT PHASE (Objective 1): Participants attend user testing interviews where they interact with LiFT application (app) prototypes and provide feedback through think-aloud methods to support refinement of the intervention content and features.
PILOT TRIAL PHASE (Objective 2): Participants are randomized to 1 of 2 arms.
- ARM I: Participants use the LiFT A app, which includes interactive games and exercises, educational content, and tools tailored to young adults using an acceptance and commitment therapy (ACT) treatment approach, for 3 months. Participants also receive associated text messages 2-3 times per week.
- ARM II: Participants use the LiFT B app, which includes educational resources on preparing to quit, nicotine withdrawal, coping with withdrawal, and mental health, along with health information videos, for 3 months. Participants also receive associated text messages 2-3 times per week.
POST PILOT TRIAL DIARY STUDY PHASE (Objective 3): Participants use the LiFT app and complete daily usability and satisfaction assessments for approximately 1 week. Participants also complete a survey and attend an interview.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 4
- Model description
- PILOT TRIAL: Parallel; USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: N/A; POST PILOT TRIAL DIARY STUDY: N/A
| Arm | Type | Receives |
|---|---|---|
| User-centered design and program development phase (interview) [Objective 1] | No intervention | –Participants attend user testing interviews where they interact with LiFT app prototypes and provide feedback through think-aloud methods to support refinement of the intervention content and features. |
| Pilot phase, Arm I (LiFT A app, LiFT A text messages) [Objective 2] | Experimental | Other: Smartphone app-based Intervention, Other: Communication intervention, Other: Survey AdministrationParticipants use the LiFT A app, which includes interactive games and exercises, educational content, and tools tailored to young adults using an ACT treatment approach, for 3 months. Participants also receive LiFT A text messages 2-3 times per week. |
| Pilot phase, Arm II (LiFT B app, LiFT B text messages) [Objective 2] | Experimental | Other: Smartphone app-based Intervention, Other: Communication intervention, Other: Survey AdministrationParticipants use the LiFT B app, which includes educational resources on preparing to quit, nicotine withdrawal, coping with withdrawal, mental health, along with health information videos, for 3 months. Participants also receive LiFT B text messages 2-3 times per week. |
| Post pilot trial diary study phase (LiFT, survey, interview) [Objective 3] | Other | Other: Smartphone app-based Intervention, Other: Interview, Other: Assessment, Other: Survey AdministrationParticipants use the LiFT app and complete daily usability and satisfaction assessments for approximately 1 week. Participants also complete a survey and attend an interview. |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (36 listed)
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-identify being between 18 and 30 years of age
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must be a United States (US) resident, with a US mailing address
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-report use of any (non-therapeutic) nicotine or tobacco product at least once per week in the 30 days prior to screening
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must own a smartphone
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Participants must self-report having internet access for the interviews
Key exclusion criteria (12 listed)
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Individuals must not be < 18 or > 30 years of age
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Individuals must not have a Google voice number as their sole phone number
- USER-CENTERED DESIGN AND PROGRAM DEVELOPMENT: Individuals who are non-English speaking cannot participate, as this would prevent their participation in the interviews, which will be conducted in English
- PILOT TRIAL: Participants must not be < 18 or > 30 years of age
- PILOT TRIAL: Participants must not be currently using other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (but initiating these treatments during the study is allowed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Smartphone app-based InterventionUse LiFT A app | Other | Pilot phase, Arm I (LiFT A app, LiFT A text messages) [Objective 2], Post pilot trial diary study phase (LiFT, survey, interview) [Objective 3] |
| Smartphone app-based InterventionUse LiFT B app | Other | Pilot phase, Arm II (LiFT B app, LiFT B text messages) [Objective 2] |
| Communication interventionReceive LiFT A text messages | Other | Pilot phase, Arm I (LiFT A app, LiFT A text messages) [Objective 2] |
| Communication interventionReceive LiFT B text messages | Other | Pilot phase, Arm II (LiFT B app, LiFT B text messages) [Objective 2] |
| Survey AdministrationComplete surveys | Other | Pilot phase, Arm I (LiFT A app, LiFT A text messages) [Objective 2], Pilot phase, Arm II (LiFT B app, LiFT B text messages) [Objective 2] |
| InterviewAttend interview | Other | Post pilot trial diary study phase (LiFT, survey, interview) [Objective 3] |
| AssessmentComplete usability assessment | Other | Post pilot trial diary study phase (LiFT, survey, interview) [Objective 3] |
| Survey AdministrationComplete survey | Other | Post pilot trial diary study phase (LiFT, survey, interview) [Objective 3] |
Primary outcome
Overall satisfaction (Pilot trial phase)
Time frame: At 3 months
Overall satisfaction with the assigned program will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Number of logins to assigned application (Pilot trial phase)
Time frame: At 3 months
Treatment utilization will include number of logins to the assigned application, determined objectively using tracking software.
Usefulness of the program (Pilot trial phase)
Time frame: At 3 months
The perceived usefulness of the assigned program will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Usefulness of text messages (Pilot trial phase)
Time frame: At 3 months
The perceived usefulness of the assigned program's text messages will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Satisfaction with perceived tailoring (Pilot trial phase)
Time frame: At 3 months
The perception that the assigned program was made for someone like the participant will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Satisfaction with guidance on how to quit (Pilot trial phase)
Time frame: At 3 months
The perception that the program clarified how to quit nicotine/tobacco when ready will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Perception that program offered a novel approach to quitting (Pilot trial phase)
Time frame: At 3 months
The perception that the program offered a new way of looking at quitting will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Perceived helpfulness for quit preparation (Pilot trial phase)
Time frame: At 3 months
The perception that the program will help with quitting if/when ready will be assessed by self-report on a 5-point Likert-type scale from "not at all" (1) to "very much" (5) and summarized by arm using means and standard deviations.
Willingness to recommend program to a friend (Pilot trial phase)
Time frame: At 3 months
Whether the respondent would recommend the program to a friend will be assessed via responses of "yes," "no," or "not sure." Responses will be categorized into a binary variable representing "yes" versus other responses (i.e.,"no" or "not sure").
Usability (Post pilot trial diary study phase)
Time frame: At completion of post pilot trial diary study phase (At Day 9)
Qualitative data from interviews, diary entries and exit interviews will be coded and analyzed using rapid inductive content analysis to extract themes. Usability data will be reported using descriptive statistics and compared against the benchmark score of 68, which represents average usability.
8 secondary outcomes
Biochemically-confirmed 7-day point prevalence abstinence (PPA) from all nicotine and tobacco use (Pilot trial phase)
Time frame: At 3 months
Self-reported 7-day PPA from all nicotine and tobacco use (Pilot trial phase)
Time frame: At 3 months
Self-reported 30-day PPA (Pilot trial phase)
Time frame: At 3 months
Cotinine-confirmed 30-day PPA (Pilot trial phase)
Time frame: At 3 months
Average change in Contemplation Ladder scores (Pilot trial phase)
Time frame: From baseline to 3 months
Change in acceptance of tobacco use triggers (Pilot trial phase)
Time frame: From baseline to 3 months
Change in values progress (Pilot trial phase)
Time frame: From baseline to 3 months
Change in values obstruction (Pilot trial phase)
Time frame: From baseline to 3 months
Results and safety
The study was stopped early (reason given: Discontinuation of funding). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Jaimee Heffner, PhD principal investigator
Fred Hutch/University of Washington Cancer Consortium
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Smartphone app-based Intervention, Communication intervention and Survey Administration in people with Tobacco-Related Carcinoma, run by Fred Hutchinson Cancer Center at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 36 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 16 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: Discontinuation of funding). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Overall satisfaction (Pilot trial phase) (time frame: At 3 months). The study lists 10 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Oct 2026.