Nerve Conduction StudyNCT07571395
Median Nerve Electromyography to Monitor Intraoperative Neuromuscular Function
An observational study of Nerve Conduction Study and Elective Surgery, run by Pongrácz Adrienn at 1 site in Hungary.
Trial summary
The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone. For this purpose, anesthesiologists use so called objective neurlmuscular monitors. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Nerve Conduction Study, Elective Surgery, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
- What is being tested?
- Electromyography
- How many people
- 45 participants
- Where
- 1 siteHungary
- Study dates
- 16 Jun 2026to 31 Mar 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients undergoing elective surgery that requires one dose of non-depolarising neuromuscular blocking agent, whose arms are accessible for intraoperative neuromuscular blockade monitoring.
Who may be able to join
- ASA I-III physical status
- elective surgery requiring muscle relaxation
- both arms are available during surgery in the same position for neuromuscular blockade monitoring
- signed informed consent form
Who cannot join
- neruomuscular disorder in patient history (eg. stroke, myasthenia)
- innervation problem in either arms (eg. carpal tunnel syndrome)
- deformity to either arms (eg. Dupyurten contracture, severe arthritis)
- Severe hepatic or renal insufficiency that affects muscle relaxant pharmacokinetics
- skin lesions at the site of electrode placement
- implanted pacemaker jelenléte
- gravidity
- muscle relaxant needs to be repeated during surgery
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Hungary1 site, 1 recruiting
- Recruiting
University of Debrecen Medical Center, Department of Anesthesiology and Intensive Care
Debrecen, 4032
Reka Nemes, MD PhD, +36309668722
About this study
Official title: Comparative Examination of Ulnar and Median Nerve Electromyography Examinations to Monitor Intraoperative Neuromuscular Function
The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone. For this purpose, anesthesiologists use so called objective neurlmuscular monitors. These monitors stimulate the ulnar nerve in the wrist and examine the evoked muscle response. The aim of this study is to examine the usability of another nerve in the wrist, the median nerve.
- Conditions
- Nerve Conduction Study, Elective Surgery, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
- Being tested
- Electromyography
- Keywords
- electromyography, neuromuscular blockade monitoring, median nerve
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ElectromyographyDiagnostic test
Electromyographic examination of the median and ulnar nerves to monitor intraoperative neuromuscular blockade
| Study group | Role | What they receive |
|---|---|---|
| Median nerve examination | Median nerves in the dominant and non-dominant hands are are examined Receives: Diagnostic Test: Electromyography | |
| Ulnar nerve examination | Ulnar nerves in the dominant and non-dominant hands are examined Receives: Diagnostic Test: Electromyography |
What is being measured
The primary outcome is the main question the study is designed to answer.
CMAP
Comparison of compound muscle action potential amplitudes evoked by median and ulnar nerve stimulation and measured at the thenar
Measured: Baseline
Secondary outcomes (2)
Recovery time
Time from muscle relaxant administration to spontaneous recovery to TOFR>0,9 monitored with median and ulnar nerve stimulation
Measured: Perioperative
Onset time
Time from administration of muscle relaxant to disappearance of twitch response (TOFC0) monitored with median and ulnar nerve stimulation
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2026
- Study start16 Jun 2026
- Primary completion31 Mar 2028 (estimated)
- Study completion31 Mar 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Nerve Conduction StudyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Pongrácz Adrienn
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Pongrácz Adrienn, University of Debrecen
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07571395
- Sponsor's protocol ID
- AITT 2026/1
- Status last verified
- Jun 2026
- First submitted
- 21 Apr 2026
- Last updated
- 17 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Examination of Ulnar and Median Nerve Electromyography Examinations to Monitor Intraoperative Neuromuscular Function
- ClinicalTrials.gov ID
- NCT07571395
- Acronym / sponsor ID
- AITT 2026/1
- Conditions
- Nerve Conduction Study, Elective Surgery, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
- Keywords
- electromyography, neuromuscular blockade monitoring, median nerve
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 45 participants (estimated)
- Lead sponsor
- Pongrácz AdriennUniversity, hospital or other
- Study start
- 16 Jun 2026 (actual)
- Primary completion
- 31 Mar 2028 (estimated)
- Study completion
- 31 Mar 2028 (estimated)
- First posted
- 6 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone. For this purpose, anesthesiologists use so called objective neurlmuscular monitors. These monitors stimulate the ulnar nerve in the wrist and examine the evoked muscle response. The aim of this study is to examine the usability of another nerve in the wrist, the median nerve.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Median nerve examination | – | Diagnostic Test: ElectromyographyMedian nerves in the dominant and non-dominant hands are are examined |
| Ulnar nerve examination | – | Diagnostic Test: ElectromyographyUlnar nerves in the dominant and non-dominant hands are examined |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adult patients undergoing elective surgery that requires one dose of non-depolarising neuromuscular blocking agent, whose arms are accessible for intraoperative neuromuscular blockade monitoring.
Key inclusion criteria (4 listed)
- ASA I-III physical status
- elective surgery requiring muscle relaxation
- both arms are available during surgery in the same position for neuromuscular blockade monitoring
- signed informed consent form
Key exclusion criteria (8 listed)
- neruomuscular disorder in patient history (eg. stroke, myasthenia)
- innervation problem in either arms (eg. carpal tunnel syndrome)
- deformity to either arms (eg. Dupyurten contracture, severe arthritis)
- Severe hepatic or renal insufficiency that affects muscle relaxant pharmacokinetics
- skin lesions at the site of electrode placement
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ElectromyographyElectromyographic examination of the median and ulnar nerves to monitor intraoperative neuromuscular blockade | Diagnostic test | Median nerve examination, Ulnar nerve examination |
Primary outcome
CMAP
Time frame: Baseline
Comparison of compound muscle action potential amplitudes evoked by median and ulnar nerve stimulation and measured at the thenar
2 secondary outcomes
Recovery time
Time frame: Perioperative
Onset time
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Nerve Conduction Study and Elective Surgery, run by Pongrácz Adrienn at 1 site in Hungary.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Hungary. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Reka Nemes, MD PhD (+36 30 966 8722, nemes.reka@med.unideb.hu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
CMAP (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jun 2026.