Skin AgingNUAANCT07571629
A 56-Day Exploratory Study of NatureU® Mind Care BeautyU Caps on Skin Aging Parameters
A study testing NatureU® Mind Care BeautyU Caps in people with Skin Aging, run by OmniSolutions Laboratory Holdings Limited at 1 site in China.
Trial summary
This was a 56-day, single-center, open-label, single-arm exploratory study evaluating within-participant changes in skin-aging parameters after daily oral intake of NatureU® Mind Care BeautyU Caps in adult women. Participants took one capsule daily for 56 days. Read more about this study
- Who is it for?
- Ages 36 to 56 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Skin Aging
- What is being tested?
- NatureU® Mind Care BeautyU Caps
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 33 participants
- Where
- 1 siteChina
- Study dates
- 11 Jan 2025to 8 Mar 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 36 to 56 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Adult woman aged 36 to 56 years, inclusive.
- Healthy participant as judged by the investigator.
- Cheek skin hydration below 60 C.U.
- Visible crow's-feet wrinkles.
- Facial laxity or reduced facial radiance.
- At least one visible facial spot meeting the prespecified size and ITA value criteria.
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- Willing to take the study product once daily for 56 consecutive days.
- Willing to complete scheduled skin assessments at baseline, Day 28, and Day 56.
- Willing to maintain regular lifestyle habits during the study period.
- Willing to avoid confounding skincare products, cosmetic procedures, medications, and health products during the study period.
- Provided written informed consent before any study-related procedure.
Who cannot join
- Skin condition that could interfere with study assessments.
- Highly allergic constitution.
- Known allergy or intolerance to any ingredient of the study product.
- Pregnant or lactating.
- Planned pregnancy during the study period.
- Severe systemic illness.
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- Serious psychiatric disorder.
- Serious endocrine disorder.
- Recent participation in another clinical study.
- Recent use of products or procedures that could influence skin outcomes.
- Use of other oral or topical products that could interfere with skin-aging assessments during the study period.
- Recent cosmetic dermatology procedures or treatments that could affect the target assessment areas.
- Inability to comply with study procedures.
- Any condition judged by the investigator to make participation inappropriate.
Trial locations and contacts
1 site in 1 country.
China1 site
CTI AiPu Medical Laboratory (Shanghai) Co., Ltd
Shanghai, Shanghai Municipality, 200040
About this study
Official title: A 56-Day Single-Arm Exploratory Study of NatureU® Mind Care BeautyU Caps on Crow's-Feet Wrinkle Count, Skin Hydration, and Related Skin-Aging Parameters in Adult Women
This was a 56-day, single-center, open-label, single-arm exploratory study evaluating within-participant changes in skin-aging parameters after daily oral intake of NatureU® Mind Care BeautyU Caps in adult women. Participants took one capsule daily for 56 days. The primary outcome was change from baseline in crow's-feet wrinkle count at Day 56 assessed by PRIMOS CR imaging. The secondary outcome was change from baseline in stratum corneum hydration at Day 56 assessed by Corneometer CM 825. Additional exploratory outcomes included other wrinkle topography parameters, skin elasticity, radiance, pigmentation, pore-related parameters, dermal thickness and density, and participant-reported skin appearance outcomes.
Read the detailed description
The study was designed as an exploratory, signal-generating human evaluation of an oral nutricosmetic supplement. Adult female participants received NatureU® Mind Care BeautyU Caps once daily for 56 days and underwent skin assessments at baseline, Day 28, and Day 56. Instrumental assessments included PRIMOS CR imaging for wrinkle-related parameters and Corneometer CM 825 measurement for stratum corneum hydration. Additional skin-aging parameters were assessed using validated or commonly used skin analysis instruments according to the study protocol. The study was single-arm and open-label, with no placebo or parallel control group. Analyses were based on participants who completed the study assessments.
- Conditions
- Skin Aging
- Being tested
- NatureU® Mind Care BeautyU Caps
- Keywords
- NatureU, oral beauty supplement, skin hydration, PQQ; quercetin; ergothioneine; proanthocyanidins.
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
NatureU® Mind Care BeautyU CapsDietary supplement
An oral nutricosmetic supplement containing PQQ, quercetin, ergothioneine, cranberry polyphenols, and related formulation components. Participants took one capsule daily for 56 days.
| Study group | Role | What they receive |
|---|---|---|
| NatureU® Mind Care BeautyU Caps | Experimental | Participants received NatureU® Mind Care BeautyU Caps, one capsule orally once daily for 56 days. Receives: Dietary Supplement: NatureU® Mind Care BeautyU Caps |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change From Baseline in Crow's-Feet Wrinkle Count at Day 56
Crow's-feet wrinkle count was assessed using PRIMOS CR imaging. The primary endpoint was the within-participant change from baseline to Day 56.
Measured: Baseline and Day 56
Secondary outcomes (1)
Change From Baseline in Stratum Corneum Hydration at Day 56
Skin hydration was assessed using Corneometer CM 825. The secondary endpoint was the within-participant change from baseline to Day 56.
Measured: Baseline and Day 56
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2026
- Study start11 Jan 2025
- Primary completion8 Mar 2025
- Study completion8 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Skin AgingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 33 participants (actual)
Sponsor and investigators
- Lead sponsor
- OmniSolutions Laboratory Holdings Limited
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
- Investigators
- Luke Law, Dr, Study director, OmniSolutions Laboratory Holdings Limited
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07571629
- Sponsor's protocol ID
- A225000034310100101C
- Other IDs
- A225000034310100101C
- Acronym
- NUAA
- Status last verified
- May 2026
- First submitted
- 30 Apr 2026
- Last updated
- 17 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared due to privacy protection and ethical considerations.
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A 56-Day Single-Arm Exploratory Study of NatureU® Mind Care BeautyU Caps on Crow's-Feet Wrinkle Count, Skin Hydration, and Related Skin-Aging Parameters in Adult Women
- ClinicalTrials.gov ID
- NCT07571629
- Acronym / sponsor ID
- NUAA / A225000034310100101C
- Conditions
- Skin Aging
- Keywords
- NatureU, oral beauty supplement, skin hydration, PQQ; quercetin; ergothioneine; proanthocyanidins.
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 33 participants (actual)
- Lead sponsor
- OmniSolutions Laboratory Holdings LimitedIndustry (pharma, biotech, devices)
- Study start
- 11 Jan 2025 (actual)
- Primary completion
- 8 Mar 2025 (actual)
- Study completion
- 8 Mar 2025 (actual)
- First posted
- 6 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This was a 56-day, single-center, open-label, single-arm exploratory study evaluating within-participant changes in skin-aging parameters after daily oral intake of NatureU® Mind Care BeautyU Caps in adult women. Participants took one capsule daily for 56 days. The primary outcome was change from baseline in crow's-feet wrinkle count at Day 56 assessed by PRIMOS CR imaging. The secondary outcome was change from baseline in stratum corneum hydration at Day 56 assessed by Corneometer CM 825. Additional exploratory outcomes included other wrinkle topography parameters, skin elasticity, radiance, pigmentation, pore-related parameters, dermal thickness and density, and participant-reported skin appearance outcomes.
Detailed description
The study was designed as an exploratory, signal-generating human evaluation of an oral nutricosmetic supplement. Adult female participants received NatureU® Mind Care BeautyU Caps once daily for 56 days and underwent skin assessments at baseline, Day 28, and Day 56. Instrumental assessments included PRIMOS CR imaging for wrinkle-related parameters and Corneometer CM 825 measurement for stratum corneum hydration. Additional skin-aging parameters were assessed using validated or commonly used skin analysis instruments according to the study protocol. The study was single-arm and open-label, with no placebo or parallel control group. Analyses were based on participants who completed the study assessments.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| NatureU® Mind Care BeautyU Caps | Experimental | Dietary Supplement: NatureU® Mind Care BeautyU CapsParticipants received NatureU® Mind Care BeautyU Caps, one capsule orally once daily for 56 days. |
Who may qualify
- Ages
- 36 to 56 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (11 listed)
- Adult woman aged 36 to 56 years, inclusive.
- Healthy participant as judged by the investigator.
- Cheek skin hydration below 60 C.U.
- Visible crow's-feet wrinkles.
- Facial laxity or reduced facial radiance.
Key exclusion criteria (14 listed)
- Skin condition that could interfere with study assessments.
- Highly allergic constitution.
- Known allergy or intolerance to any ingredient of the study product.
- Pregnant or lactating.
- Planned pregnancy during the study period.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| NatureU® Mind Care BeautyU CapsAn oral nutricosmetic supplement containing PQQ, quercetin, ergothioneine, cranberry polyphenols, and related formulation components. Participants took one capsule daily for 56 days. | Dietary supplement | NatureU® Mind Care BeautyU Caps |
Primary outcome
Change From Baseline in Crow's-Feet Wrinkle Count at Day 56
Time frame: Baseline and Day 56
Crow's-feet wrinkle count was assessed using PRIMOS CR imaging. The primary endpoint was the within-participant change from baseline to Day 56.
1 secondary outcome
Change From Baseline in Stratum Corneum Hydration at Day 56
Time frame: Baseline and Day 56
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared due to privacy protection and ethical considerations.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Luke Law, Dr study director
OmniSolutions Laboratory Holdings Limited
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing NatureU® Mind Care BeautyU Caps in people with Skin Aging, run by OmniSolutions Laboratory Holdings Limited at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 14 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change From Baseline in Crow's-Feet Wrinkle Count at Day 56 (time frame: Baseline and Day 56). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2026.