Maxillary Transversal DeficiencyNCT07579091
Correlation Between Nasal Septal Deviation and Transverse Maxillary Deficiency on CT Scans
An observational study of Maxillary Transversal Deficiency, run by Central Hospital, Nancy, France at 1 site in France.
Trial summary
The maxillary bones and the nasal septum are interconnected structures. The nasal septum acts as a growth center that facilitates normal maxillofacial growth and development. The objective of this study is to evaluate the presence or absence of septal deviation, as well as its degree of severity, within two adult… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Maxillary Transversal Deficiency
- How many people
- 223 participants
- Where
- 1 siteFrance
- Study dates
- 7 Feb 2026to 7 Apr 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Deceased from natural causes and underwent a whole-body CT scan between 2010 and 2017, in the State of New Mexico (USA)
Who may be able to join
- Adult with completed growth (> 18 years old)
- Deceased from natural causes and underwent a whole-body CT scan between 2010 and 2017, in the State of New Mexico (USA)
- Presence of maxillar and mandibular teeth from first molar to first molar (from 6 to 6)
- No body decomposition at the time of the CT scan
Who cannot join
- History of maxillofacial surgery or trauma
- Congenital craniofacial pathologies or anomalies
- Presence of maxillary or mandibular orthodontic appliances (or retainers)
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Correlation Between Nasal Septal Deviation and Transverse Maxillary Deficiency : a Retrospective Study on CT Scan
The maxillary bones and the nasal septum are interconnected structures. The nasal septum acts as a growth center that facilitates normal maxillofacial growth and development. The objective of this study is to evaluate the presence or absence of septal deviation, as well as its degree of severity, within two adult population groups with or without maxillary transverse deficiency. This is a retrospective CT scan study. While several studies have been conducted in this field, our study is original in its approach to: maxillary transverse deficiency as a measure of the transverse dimension of the maxilla, the use of CT scans as the radiological medium for evaluating the primary endpoint, and finally, the specific method used to measure septal deviation.
If a correlation exists between the two, it would be interesting to investigate whether maxillary transverse deficiency leads to septal deviation, or if septal deviation contributes to maxillary deficiency through nasal obstruction. This could highlight the importance of early management of both maxillary transverse deficiency and nasal obstruction.
In adult patients, it could support the idea of performing a single combined procedure involving maxillary expansion and septoplasty, which would reduce comorbidities and risks; ultimately representing a true benefit for the patient.
Read the detailed description
The study is a non-interventional (observational) research involving the human person, research on existing data (retrospective study).
This study analyzes the maxillary transverse deficiency and the septal deviation This is a comparative retrospective study of radiographs in three dimensions before any orthodontic treatment to study a potential correlation.
- Conditions
- Maxillary Transversal Deficiency
- Keywords
- transverse maxillary deficiency, endognathia, septal deviation, CT scan, nasal septal deviation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Patient with maxillary transverse deficiency | Patient with maxillary constriction | |
| Patient without maxillary transverse deficiency | Patient without maxillary constriction |
What is being measured
The primary outcome is the main question the study is designed to answer.
Nasal septal deviation measured by coronal CT scan
Measured: one day
Secondary outcomes (6)
Width of the piriform apertures measured by coronal CT scan
Measured: one day
Depth of the palatal vault measured by sagittal CT scan
Measured: one day
location of the septal deviation measured by coronal CT scan
Measured: one day
degree of septal deviation and depth of the palatal vault
Measured: one day
width of the piriform apertures and depth of the palatal vault
Measured: one day
height of the septal deviation and depth of the palatal vault
Measured: one day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study start7 Feb 2026
- Primary completion10 Mar 2026
- Study completion7 Apr 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Maxillary Transversal DeficiencyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Retrospective
- Enrolment
- 223 participants (actual)
Sponsor and investigators
- Lead sponsor
- Central Hospital, Nancy, France
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, VANDE VANNET Bart, Central Hospital, Nancy, France
- Investigators
- Bart Vande Vannet, Study director, Central Hospital, Nancy, France
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07579091
- Sponsor's protocol ID
- 2025PI134
- Status last verified
- Apr 2026
- First submitted
- 29 Apr 2026
- Last updated
- 11 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 11 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Correlation Between Nasal Septal Deviation and Transverse Maxillary Deficiency : a Retrospective Study on CT Scan
- ClinicalTrials.gov ID
- NCT07579091
- Acronym / sponsor ID
- 2025PI134
- Conditions
- Maxillary Transversal Deficiency
- Keywords
- transverse maxillary deficiency, endognathia, septal deviation, CT scan, nasal septal deviation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 223 participants (actual)
- Lead sponsor
- Central Hospital, Nancy, FranceUniversity, hospital or other
- Study start
- 7 Feb 2026 (actual)
- Primary completion
- 10 Mar 2026 (actual)
- Study completion
- 7 Apr 2026 (actual)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The maxillary bones and the nasal septum are interconnected structures. The nasal septum acts as a growth center that facilitates normal maxillofacial growth and development. The objective of this study is to evaluate the presence or absence of septal deviation, as well as its degree of severity, within two adult population groups with or without maxillary transverse deficiency. This is a retrospective CT scan study. While several studies have been conducted in this field, our study is original in its approach to: maxillary transverse deficiency as a measure of the transverse dimension of the maxilla, the use of CT scans as the radiological medium for evaluating the primary endpoint, and finally, the specific method used to measure septal deviation.
If a correlation exists between the two, it would be interesting to investigate whether maxillary transverse deficiency leads to septal deviation, or if septal deviation contributes to maxillary deficiency through nasal obstruction. This could highlight the importance of early management of both maxillary transverse deficiency and nasal obstruction.
In adult patients, it could support the idea of performing a single combined procedure involving maxillary expansion and septoplasty, which would reduce comorbidities and risks; ultimately representing a true benefit for the patient.
Detailed description
The study is a non-interventional (observational) research involving the human person, research on existing data (retrospective study).
This study analyzes the maxillary transverse deficiency and the septal deviation This is a comparative retrospective study of radiographs in three dimensions before any orthodontic treatment to study a potential correlation.
Study design
- Observational model
- Other
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Patient with maxillary transverse deficiency | – | –Patient with maxillary constriction |
| Patient without maxillary transverse deficiency | – | –Patient without maxillary constriction |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Deceased from natural causes and underwent a whole-body CT scan between 2010 and 2017, in the State of New Mexico (USA)
Key inclusion criteria (4 listed)
- Adult with completed growth (> 18 years old)
- Deceased from natural causes and underwent a whole-body CT scan between 2010 and 2017, in the State of New Mexico (USA)
- Presence of maxillar and mandibular teeth from first molar to first molar (from 6 to 6)
- No body decomposition at the time of the CT scan
Key exclusion criteria (3 listed)
- History of maxillofacial surgery or trauma
- Congenital craniofacial pathologies or anomalies
- Presence of maxillary or mandibular orthodontic appliances (or retainers)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Nasal septal deviation measured by coronal CT scan
Time frame: one day
6 secondary outcomes
Width of the piriform apertures measured by coronal CT scan
Time frame: one day
Depth of the palatal vault measured by sagittal CT scan
Time frame: one day
location of the septal deviation measured by coronal CT scan
Time frame: one day
degree of septal deviation and depth of the palatal vault
Time frame: one day
width of the piriform apertures and depth of the palatal vault
Time frame: one day
height of the septal deviation and depth of the palatal vault
Time frame: one day
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 May 2026.
- Individual participant dataSharing planned: Undecided
Related trials for Maxillary Transversal Deficiency
Recruiting
Orofacial Muscle Pressure and Maxillary Transverse Development
Maxillary Transversal Deficiency (Maxillary Constriction) and Perioral Muscle Pressures (Tongue, Lip, and Cheek)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Bart Vande Vannet study director
Central Hospital, Nancy, France
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Maxillary Transversal Deficiency, run by Central Hospital, Nancy, France at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Nasal septal deviation measured by coronal CT scan (time frame: one day). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 May 2026; AzTrials last refreshed its copy on 30 Oct 2026.