Overweight and/or ObesityWB-HIITNCT07582718
Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults
A study testing Whole-Body High-Intensity Interval Training (WB-HIIT) in people with Overweight and/or Obesity, run by Université Libre de Bruxelles at 1 site in Belgium.
Trial summary
This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity. Read more about this study
- Who is it for?
- Ages 18 to 55 years
- Conditions the study is for
- Overweight and/or Obesity
- What is being tested?
- Whole-Body High-Intensity Interval Training (WB-HIIT)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteBelgium
- Study dates
- 9 Nov 2022to Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adults aged 18 to 55 years.
- Body mass index (BMI) between 25 and 35 kg/m².
- Able to provide written informed consent.
- Able to safely participate in high-intensity interval training.
- For participants with BMI > 30 kg/m²: medical clearance from their general practitioner.
Who cannot join
- BMI < 25 or > 35 kg/m².
- Presence of any chronic medical condition other than overweight/obesity.
- Known cardiovascular, metabolic, respiratory, or musculoskeletal disease that contraindicates high-intensity exercise.
- Pregnancy.
- Inability to perform exercise testing or complete the WB-HIIT program.
- Any condition judged by investigators to interfere with participation or data interpretation.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Belgium1 site, 1 recruiting
- Recruiting
Université libre de Bruxelles (ULB)
Brussels
About this study
Official title: Effects of a Whole-body High-intensity Interval Training on Cardiorespiratory Fitness, Musculoskeletal Fitness, Body Composition and Blood Parameters in Overweight Subjects
This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity. WB-HIIT is a practical and time-efficient training modality based on body-weight exercises performed at high intensity with short recovery intervals. It may offer an accessible approach for improving health in individuals with excess body weight.
Participants aged 18 to 55 years with a body mass index (BMI) between 25 and 35 kg/m² will take part in a supervised 10-week WB-HIIT program, performed in small groups and led by trained exercise professionals. Before and after the intervention, participants will undergo assessments including DXA-based body composition analysis, fasting blood sampling, muscular strength testing, a Chester step test, a maximal graded treadmill exercise test with gas-exchange analysis to determine VO₂peak, and functional evaluations (chair-stand, arm-curl, and 6-minute walk test). Physical activity and dietary intake will also be recorded.
Read more
The primary objective of the study is to assess whether WB-HIIT improves cardiorespiratory fitness (VO₂peak) in adults with overweight. Secondary objectives include evaluating changes in muscular strength, body composition, metabolic markers, and functional capacity.
The results may help determine whether an equipment-free WB-HIIT program can serve as an effective and accessible training approach for improving health and physical fitness in adults with overweight and obesity.
Read the detailed description
This study investigates the physiological, functional, and metabolic effects of a supervised whole-body high-intensity interval training (WB-HIIT) program conducted entirely in person in adults with overweight and obesity.
Overweight and obesity are associated with decreased cardiorespiratory fitness, metabolic impairments, and increased risk of chronic diseases. In contrast, regular physical activity is known to improve cardiorespiratory fitness, metabolic health, body composition, strength, and quality of life. WB-HIIT, which involves body-weight exercises performed at high intensity with controlled recovery intervals, provides a time-efficient, equipment-free training modality that can be adapted for individuals with excess body weight.
A total of 40 adults aged 18 to 55 years with a BMI between 25 and 35 kg/m² will be recruited and allocated to an intervention and control group. In the intervention group, participants will complete a 10-week supervised WB-HIIT program consisting of 2 to 3 sessions per week. Training sessions will include 8 to 12 whole-body exercises targeting major muscle groups, performed in intervals lasting 20 to 60 seconds with recovery periods adjusted according to participant progression. Intensity will be monitored through heart rate and perceived exertion (Borg CR-10 scale), and progression will be achieved by modifying the number of sets, exercise complexity, and work-to-rest ratio.
All participants will undergo comprehensive pre- and post-intervention evaluations. Body composition will be measured using DXA, and anthropometric measurements will include waist circumference and BMI. Cardiometabolic health will be assessed through fasting blood sampling measuring glucose, insulin, HbA1c, lipid profile, hepatic markers, and additional exploratory biomarkers. Cardiorespiratory fitness will be evaluated using a maximal graded treadmill test with gas exchange analysis to determine VO₂peak and the Chester step test. Functional performance will be assessed through the 30-second chair-stand test, arm-curl test, and 6-minute walk test. Muscular strength will be evaluated through 3-repetition maximum (3-RM) testing and fatigue protocols at 60% of 1-RM for the leg-press and bench-press exercises. Physical activity and dietary habits will also be evaluated before and after the intervention.
The primary outcomes of the study are the changes in VO₂peak and muscle strength following the intervention. Secondary outcomes include changes in body composition, metabolic parameters, and functional capacity. Statistical analyses will include repeated-measures ANOVA and between-group comparisons using parametric or non-parametric methods as appropriate.
This study aims to deepen understanding of the effects of supervised WB-HIIT in overweight adults and to identify practical, scalable training methods that can be implemented in community or clinical settings. The findings may guide the development of accessible exercise-based health strategies for improving fitness and metabolic health in this population.
- Conditions
- Overweight and/or Obesity
- Being tested
- Whole-Body High-Intensity Interval Training (WB-HIIT)
- Keywords
- Overweight, Cardiorespiratory Fitness, Body Composition, Muscular Strength, Whole-Body HIIT, Body-Weight Exercise, Metabolic health
- Medical subject headings
- Overweight
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Whole-Body High-Intensity Interval Training (WB-HIIT)Behavioural
A structured WB-HIIT program using body-weight exercises such as squats, lunges, mountain climbers, and similar multi-joint movements. Sessions last 35-50 minutes and include 3 to 4 sets of interval blocks performed at high intensity. The training is supervised by qualified exercise professionals.
| Study group | Role | What they receive |
|---|---|---|
| WB-HIIT Intervention | Experimental | A supervised whole-body high-intensity interval training (WB-HIIT) program performed in small groups. Participants complete 2 to 3 sessions per week for 10 weeks. Each session includes a warm-up followed by 8 to 12 whole-body exercises performed at high intensity for 20-60 seconds with recovery periods of 20-60 seconds. Progression is applied by adjusting exercise complexity, number of sets, and work-to-rest ratio. Heart rate and perceived exertion (Borg CR-10 scale) are monitored. Receives: Behavioral: Whole-Body High-Intensity Interval Training (WB-HIIT) |
| Control Group | No intervention | Participants in the control group do not receive structured exercise training. They maintain their usual lifestyle and complete the same pre- and post-intervention assessments as the intervention group. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Peak oxygen consumption (VO₂peak)
Peak oxygen consumption (VO₂peak) will be measured during a maximal graded treadmill exercise test with gas analysis to assess changes in cardiorespiratory fitness following the 10-week WB-HIIT program. VO₂peak will be expressed in mL·kg-¹·min-¹.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Muscular strength
Maximal dynamic strength will be assessed using 3-repetition maximum (3-RM) tests on the leg press and bench press.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Secondary outcomes (13)
Estimated VO₂max from the Chester Step Test
Cardiorespiratory fitness will also be estimated using the Chester Step Test to evaluate submaximal aerobic capacity.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Body composition
Total and segmental (i.e., arms, legs and trunk) body fat mass, lean mass, and visceral fat will be assessed using dual-energy X-ray absorptiometry (DXA). They will all be expressed in kg.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Muscular endurance (fatigue tests at 60% 1-RM)
Muscular endurance will be evaluated by recording the number of repetitions performed at 60% of the estimated 1-RM for leg press and bench press.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Functional performance (chair-stand test)
Lower-body function will be assessed using the 30-second chair-stand test.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Upper-body functional performance (arm-curl test)
Upper-body functional performance will be measured using the 30-second arm-curl test with standardized weights (2 kg for women, 4 kg for men).
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Functional capacity (6-minute walk test)
Functional aerobic capacity will be assessed during a standardized 6-minute walk test, recording distance walked and recovery heart rate.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Blood biomarkers
Fasting blood markers will include glucose, insulin, HbA1c, lipid profile (total cholesterol, HDL, triglycerides), liver enzymes, and exploratory metabolic biomarkers.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Waist circumference
Waist circumference will be measured at the midpoint between the lower rib and iliac crest to assess changes in abdominal adiposity.
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Physical activity level using the International Physical Activity Questionnaire
Self-reported physical activity will be assessed using the short format of the International Physical Activity Questionnaire (IPAQ-short form).
The IPAQ-short form assesses physical activity over the past seven days by recording time spent in vigorous activity, moderate activity, walking, and sitting.
It converts the time spent in different physical activity intensities into total energy expenditure, expressed in MET-minutes per week. Walking, moderate activity, and vigorous activity are assigned MET values of 3.3, 4.0, and 8.0 respectively.
Based on an individual's responses, the physical activity level can be expressed continuously (MET-min per week), or categorised has low, moderate and high (please refer to: https://sites.google.com/view/ipaq/score). Higher values/scores mean a higher level of physical activity.
Measured: At Baseline
Dietary intake (3-day food record)
Dietary intake will be evaluated using a 3-day food record analyzed with standardized nutrition software.
Measured: The outcome will be assessed once at baseline and once during the week following completion of the whole-body high-intensity interval training intervention.
Weight
Weight will be measured using a scale (in kilograms).
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Height
Height will be measured using stadiometer (in meters).
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Body mass index
Weight and height will be combined to report body mass index, expressed in kg/m²
Measured: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 May 2026
- Study start9 Nov 2022
- Primary completionJun 2026 (estimated)
- Study completionJun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Overweight and/or ObesityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- Participants are allocated into two parallel groups (intervention vs. control) using semi-stratified assignment based on age, BMI, and sex to balance baseline characteristics. The intervention group completes a supervised 10-week WB-HIIT program, while the control group maintains usual lifestyle habits. All participants undergo identical pre- and post-intervention assessments.
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Université Libre de Bruxelles
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Malgorzata Klass, Université Libre de Bruxelles
- Investigators
- Malgorzata Klass, PhD; Prof., Study director, Université libre de Bruxelles (ULB), Research Unit in Cardio-respiratory Physiology, Exercise & Nutrition
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07582718
- Sponsor's protocol ID
- ULB-WBHIIT-OVERWEIGHT-2026-01
- Other IDs
- P2022-344
- Acronym
- WB-HIIT
- Status last verified
- May 2026
- First submitted
- 19 Feb 2026
- Last updated
- 13 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared due to confidentiality requirements and restrictions imposed by the ethics committee.
Publications
Scoubeau C, Bonnechere B, Cnop M, Faoro V, Klass M. Effectiveness of Whole-Body High-Intensity Interval Training on Health-Related Fitness: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2022 Aug 3;19(15):9559. doi: 10.3390/ijerph19159559.
PubMed 35954911Scoubeau C, Carpentier J, Baudry S, Faoro V, Klass M. Body composition, cardiorespiratory fitness, and neuromuscular adaptations induced by a home-based whole-body high intensity interval training. J Exerc Sci Fit. 2023 Apr;21(2):226-236. doi: 10.1016/j.jesf.2023.02.004. Epub 2023 Mar 10.
PubMed 36970125
Study at a glance
From the registry record, last updated by the sponsor on 13 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of a Whole-body High-intensity Interval Training on Cardiorespiratory Fitness, Musculoskeletal Fitness, Body Composition and Blood Parameters in Overweight Subjects
- ClinicalTrials.gov ID
- NCT07582718
- Acronym / sponsor ID
- WB-HIIT / ULB-WBHIIT-OVERWEIGHT-2026-01
- Conditions
- Overweight and/or Obesity
- Keywords
- Overweight, Cardiorespiratory Fitness, Body Composition, Muscular Strength, Whole-Body HIIT, Body-Weight Exercise, Metabolic health
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Université Libre de BruxellesUniversity, hospital or other
- Study start
- 9 Nov 2022 (actual)
- Primary completion
- Jun 2026 (estimated)
- Study completion
- Jun 2026 (estimated)
- First posted
- 13 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity. WB-HIIT is a practical and time-efficient training modality based on body-weight exercises performed at high intensity with short recovery intervals. It may offer an accessible approach for improving health in individuals with excess body weight.
Participants aged 18 to 55 years with a body mass index (BMI) between 25 and 35 kg/m² will take part in a supervised 10-week WB-HIIT program, performed in small groups and led by trained exercise professionals. Before and after the intervention, participants will undergo assessments including DXA-based body composition analysis, fasting blood sampling, muscular strength testing, a Chester step test, a maximal graded treadmill exercise test with gas-exchange analysis to determine VO₂peak, and functional evaluations (chair-stand, arm-curl, and 6-minute walk test). Physical activity and dietary intake will also be recorded.
The primary objective of the study is to assess whether WB-HIIT improves cardiorespiratory fitness (VO₂peak) in adults with overweight. Secondary objectives include evaluating changes in muscular strength, body composition, metabolic markers, and functional capacity.
The results may help determine whether an equipment-free WB-HIIT program can serve as an effective and accessible training approach for improving health and physical fitness in adults with overweight and obesity.
Detailed description
This study investigates the physiological, functional, and metabolic effects of a supervised whole-body high-intensity interval training (WB-HIIT) program conducted entirely in person in adults with overweight and obesity.
Overweight and obesity are associated with decreased cardiorespiratory fitness, metabolic impairments, and increased risk of chronic diseases. In contrast, regular physical activity is known to improve cardiorespiratory fitness, metabolic health, body composition, strength, and quality of life. WB-HIIT, which involves body-weight exercises performed at high intensity with controlled recovery intervals, provides a time-efficient, equipment-free training modality that can be adapted for individuals with excess body weight.
A total of 40 adults aged 18 to 55 years with a BMI between 25 and 35 kg/m² will be recruited and allocated to an intervention and control group. In the intervention group, participants will complete a 10-week supervised WB-HIIT program consisting of 2 to 3 sessions per week. Training sessions will include 8 to 12 whole-body exercises targeting major muscle groups, performed in intervals lasting 20 to 60 seconds with recovery periods adjusted according to participant progression. Intensity will be monitored through heart rate and perceived exertion (Borg CR-10 scale), and progression will be achieved by modifying the number of sets, exercise complexity, and work-to-rest ratio.
All participants will undergo comprehensive pre- and post-intervention evaluations. Body composition will be measured using DXA, and anthropometric measurements will include waist circumference and BMI. Cardiometabolic health will be assessed through fasting blood sampling measuring glucose, insulin, HbA1c, lipid profile, hepatic markers, and additional exploratory biomarkers. Cardiorespiratory fitness will be evaluated using a maximal graded treadmill test with gas exchange analysis to determine VO₂peak and the Chester step test. Functional performance will be assessed through the 30-second chair-stand test, arm-curl test, and 6-minute walk test. Muscular strength will be evaluated through 3-repetition maximum (3-RM) testing and fatigue protocols at 60% of 1-RM for the leg-press and bench-press exercises. Physical activity and dietary habits will also be evaluated before and after the intervention.
The primary outcomes of the study are the changes in VO₂peak and muscle strength following the intervention. Secondary outcomes include changes in body composition, metabolic parameters, and functional capacity. Statistical analyses will include repeated-measures ANOVA and between-group comparisons using parametric or non-parametric methods as appropriate.
This study aims to deepen understanding of the effects of supervised WB-HIIT in overweight adults and to identify practical, scalable training methods that can be implemented in community or clinical settings. The findings may guide the development of accessible exercise-based health strategies for improving fitness and metabolic health in this population.
Study design
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants are allocated into two parallel groups (intervention vs. control) using semi-stratified assignment based on age, BMI, and sex to balance baseline characteristics. The intervention group completes a supervised 10-week WB-HIIT program, while the control group maintains usual lifestyle habits. All participants undergo identical pre- and post-intervention assessments.
| Arm | Type | Receives |
|---|---|---|
| WB-HIIT Intervention | Experimental | Behavioral: Whole-Body High-Intensity Interval Training (WB-HIIT)A supervised whole-body high-intensity interval training (WB-HIIT) program performed in small groups. Participants complete 2 to 3 sessions per week for 10 weeks. Each session includes a warm-up followed by 8 to 12 whole-body exercises performed at high intensity for 20-60 seconds with recovery periods of 20-60 seconds. Progression is applied by adjusting exercise complexity, number of sets, and work-to-rest ratio. Heart rate and perceived exertion (Borg CR-10 scale) are monitored. |
| Control Group | No intervention | –Participants in the control group do not receive structured exercise training. They maintain their usual lifestyle and complete the same pre- and post-intervention assessments as the intervention group. |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Adults aged 18 to 55 years.
- Body mass index (BMI) between 25 and 35 kg/m².
- Able to provide written informed consent.
- Able to safely participate in high-intensity interval training.
- For participants with BMI > 30 kg/m²: medical clearance from their general practitioner.
Key exclusion criteria (6 listed)
- BMI < 25 or > 35 kg/m².
- Presence of any chronic medical condition other than overweight/obesity.
- Known cardiovascular, metabolic, respiratory, or musculoskeletal disease that contraindicates high-intensity exercise.
- Pregnancy.
- Inability to perform exercise testing or complete the WB-HIIT program.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Whole-Body High-Intensity Interval Training (WB-HIIT)A structured WB-HIIT program using body-weight exercises such as squats, lunges, mountain climbers, and similar multi-joint movements. Sessions last 35-50 minutes and include 3 to 4 sets of interval blocks performed at high intensity. The training is supervised by qualified exercise professionals. | Behavioural | WB-HIIT Intervention |
Primary outcome
Peak oxygen consumption (VO₂peak)
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Peak oxygen consumption (VO₂peak) will be measured during a maximal graded treadmill exercise test with gas analysis to assess changes in cardiorespiratory fitness following the 10-week WB-HIIT program. VO₂peak will be expressed in mL·kg-¹·min-¹.
Muscular strength
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Maximal dynamic strength will be assessed using 3-repetition maximum (3-RM) tests on the leg press and bench press.
13 secondary outcomes
Estimated VO₂max from the Chester Step Test
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Body composition
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Muscular endurance (fatigue tests at 60% 1-RM)
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Functional performance (chair-stand test)
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Upper-body functional performance (arm-curl test)
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Functional capacity (6-minute walk test)
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Blood biomarkers
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Waist circumference
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Physical activity level using the International Physical Activity Questionnaire
Time frame: At Baseline
Dietary intake (3-day food record)
Time frame: The outcome will be assessed once at baseline and once during the week following completion of the whole-body high-intensity interval training intervention.
Weight
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Height
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Body mass index
Time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 May 2026.
- Background: PubMed 35954911Scoubeau C, Bonnechere B, Cnop M, Faoro V, Klass M. Effectiveness of Whole-Body High-Intensity Interval Training on Health-Related Fitness: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2022 Aug 3;19(15):9559. doi: 10.3390/ijerph19159559.
- Background: PubMed 36970125Scoubeau C, Carpentier J, Baudry S, Faoro V, Klass M. Body composition, cardiorespiratory fitness, and neuromuscular adaptations induced by a home-based whole-body high intensity interval training. J Exerc Sci Fit. 2023 Apr;21(2):226-236. doi: 10.1016/j.jesf.2023.02.004. Epub 2023 Mar 10.
- Individual participant dataSharing planned: No. Individual participant data will not be shared due to confidentiality requirements and restrictions imposed by the ethics committee.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Malgorzata Klass, PhD; Prof. study director
Université libre de Bruxelles (ULB), Research Unit in Cardio-respiratory Physiology, Exercise & Nutrition
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Whole-Body High-Intensity Interval Training (WB-HIIT) in people with Overweight and/or Obesity, run by Université Libre de Bruxelles at 1 site in Belgium.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 13 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Belgium. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Julie Carpentier, PhD (+3225553859, julie.carpentier@ulb.be), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Peak oxygen consumption (VO₂peak) (time frame: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07582718, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 May 2026.