an Initial Order for a Blood Draw and Placement of an IV Line in the Emergency DepartmentPERFEKTONCT07584590
A Brief Intervention by Nurses to Reduce the Prescribing of Occluded Peripheral Venous Catheters in the Emergency Department
A study testing question for the prescriber in people with an Initial Order for a Blood Draw and Placement of an IV Line in the Emergency Department, run by University Hospital, Rouen at 16 sites in France.
Trial summary
Peripheral venous catheters are frequently inserted in hospitals, with approximately 25 million placed annually in France (HAS data, 2005). The occluded peripheral venous catheter with extension tubing has become the standard in some emergency departments, offering advantages such as patient mobility, the ability to… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- an Initial Order for a Blood Draw and Placement of an IV Line in the Emergency Department
- What is being tested?
- question for the prescriber
- Type of treatment
- Injection or infusion
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,680 participants
- Where
- 16 sitesFrance
- Study dates
- 1 Jun 2026to 1 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients assigned a triage score of 3A, 3B, or 4 according to the French triage scale, or 3 or 4 according to the CIMU triage scale, by the triage nurse
- Patients with a blood draw order involving the placement of an occluded catheter
- Age 18 years or older
- Patients who have read and understood the information sheet
- Patients who have given their verbal consent to participate in the study
- Patients enrolled in a social security program
Who cannot join
- Patients admitted to the emergency department with a pre-existing intravenous line
- Patients treated by the Mobile Emergency and Resuscitation Unit outside the hospital
- Patients with a blocked catheter who did not undergo an initial blood draw
- Patient with known neurocognitive disorders incompatible with informed consent
- Pregnant or breastfeeding woman
- Patient under legal guardianship (guardianship or conservatorship) or patient deprived of liberty
- Patient refusing to participate in the study
- Patient participating in another interventional research study
Trial locations and contacts
16 sites in 1 country. Contact the study team or a site near you to ask about taking part.
ROUSSEL Mélanie, MD contact
16 sites in 1 country
France16 sites
CHU Amiens
Amiens, 80 000
Emilen ARNAUD, Arnaud.emilien@chu-amiens.fr
CHU Angers
Angers, 49 100
Vanessa TOULIER, Vanessa.toulier@chu-angers.fr
Chu Clermont Ferrand
Clermont-Ferrand, 63 000
Dorian TEISSANDIER, dteissandier@chu-clermontferrand.fr
APHP Henri Mondor
Créteil, 94 010
Christian Kassasseya, Christian.kassasseya@aphp.fr
Ch Dieppe
Dieppe, 76 202
Xavier LAKERMANCE, xlakermance@ch-dieppe.fr
APHP CH Simone Veil
Eaubonne, 95 600
Diarra SYLLAH, Diarrah.sylla@ch-simoneveil.fr
HCL Lyon Sud
Lyon, 69 495
marion Douplat, Marion.douplat@chu-lyon.fr
HIA Laveran Marseille
Marseille, 13013
Nicolas CAZES, Nicolas.cazes@intradef.gouv.fr
CHRU Nancy
Nancy, 54 000
Tahar CHOUIHED, t.choulhed@chru-nancy.fr
CHU Nantes
Nantes, 44 093
François JAVAUDIN, Francoi.javaudin@chu-nantes.fr
APHP Lariboisière
Paris, 75 010
Anthony CHAUVIN, Anthony.chauvin@aphp.fr
AP HP Pitié Salpétrière
Paris, 75 013
Amélie VROMANT, amelie.vromant@aphp.fr
APHP Bichat
Paris, 75 018
Donia BOUZID, Donia.bouzid@aphp.fr
APHP St Antoine
Paris, 76 012
Florent NOEL, Florent.noel@aphp.fr
CHU de ROUEN
Rouen, 76 031
Jessica BORTZMEYER, jessica.bortzmeyer@chu-rouen.fr
Chu Toulouse
Toulouse, 31 300
Thomas PARDON, Pardon.t@toulouse.fr
About this study
Peripheral venous catheters are frequently inserted in hospitals, with approximately 25 million placed annually in France (HAS data, 2005). The occluded peripheral venous catheter with extension tubing has become the standard in some emergency departments, offering advantages such as patient mobility, the ability to perform repeated blood draws, and the administration of intravenous medications. A 2018 meta-analysis revealed that one in three devices was unnecessary. The placement of a occluded peripheral venous is associated with a more painful insertion, higher cost, and an increased risk of infection and thromboembolism, and blood samples obtained via the occluded peripheral venous catheter are more often hemolyzed than those obtained by direct venipuncture.
Communication between physicians and nurses is essential to ensure optimal patient care. A brief intervention by the nurse when a physician prescribes a occluded peripheral venous catheter can help clarify the appropriateness of this prescription, which could lead to reduced pain for the patient, time savings for healthcare providers, and material cost savings for the hospital.
- Being tested
- question for the prescriber
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
question for the prescriberOther
Once the nurse has received the doctor's order for a blood draw with a KTO, she will ask the prescribing physician: Is the KTO being prescribed for: the administration of medication? The injection of a contrast agent? A second blood draw? For each question, there are three possible answers: Yes? No? Maybe?
| Study group | Role | What they receive |
|---|---|---|
| Questions for the prescriber | Experimental | Once the nurse has received the doctor's order for a blood draw with a KTO, she will ask the prescribing physician: Is the KTO being prescribed for: the administration of medication? The injection of a contrast agent? A second blood draw? For each question, there are three possible answers: Yes? No? Maybe? Receives: Other: question for the prescriber |
What is being measured
The primary outcome is the main question the study is designed to answer.
the proportion of obturator catheters placed improperly
Questions for the prescriber
Measured: day 1
Secondary outcomes (5)
Correlation between the physician's final decision and nurse activity
Correlation between the physician's final decision and the performance of a repeat biopsy, the administration of contrast dye, or the administration of intravenous treatment
Measured: day 1
Use of the numerical pain scale during obturator catheter placement
pain during obturator catheter placement
Measured: at the end of procedure (assessed up to 20 minutes)
Micro-costing analysis
Micro-costing analysis of the cost of a standard venous blood draw and a closed-catheter procedure
Measured: at the end of procedure (assessed up to 20 minutes)
Types of intravenous medications administered
Types of intravenous medications administered and available oral alternatives
Measured: day 1
Number of orders for obturator catheters
Number of orders for obturator catheters placement during the initial blood draw for each period throughout the entire enrollment period
Measured: day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 May 2026
- Study start1 Jun 2026 (estimated)
- Primary completion1 Jan 2027 (estimated)
- Study completion1 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for an Initial Order for a Blood Draw and Placement of an IV Line in the Emergency DepartmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Sequential
- Masking
- None (open label)
- Enrolment
- 1,680 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Rouen
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Déborah LEBEDIEFF, MS, Study chair, University Hospital, Rouen
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07584590
- Sponsor's protocol ID
- 2023/0302/HP
- Acronym
- PERFEKTO
- Status last verified
- May 2026
- First submitted
- 27 Mar 2026
- Last updated
- 13 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Brief Intervention by Nurses to Reduce the Prescribing of Occluded Peripheral Venous Catheters in the Emergency Department
- ClinicalTrials.gov ID
- NCT07584590
- Acronym / sponsor ID
- PERFEKTO / 2023/0302/HP
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 1,680 participants (estimated)
- Lead sponsor
- University Hospital, RouenUniversity, hospital or other
- Study start
- 1 Jun 2026 (estimated)
- Primary completion
- 1 Jan 2027 (estimated)
- Study completion
- 1 Jan 2027 (estimated)
- First posted
- 13 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Peripheral venous catheters are frequently inserted in hospitals, with approximately 25 million placed annually in France (HAS data, 2005). The occluded peripheral venous catheter with extension tubing has become the standard in some emergency departments, offering advantages such as patient mobility, the ability to perform repeated blood draws, and the administration of intravenous medications. A 2018 meta-analysis revealed that one in three devices was unnecessary. The placement of a occluded peripheral venous is associated with a more painful insertion, higher cost, and an increased risk of infection and thromboembolism, and blood samples obtained via the occluded peripheral venous catheter are more often hemolyzed than those obtained by direct venipuncture.
Communication between physicians and nurses is essential to ensure optimal patient care. A brief intervention by the nurse when a physician prescribes a occluded peripheral venous catheter can help clarify the appropriateness of this prescription, which could lead to reduced pain for the patient, time savings for healthcare providers, and material cost savings for the hospital.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Sequential
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Questions for the prescriber | Experimental | Other: question for the prescriberOnce the nurse has received the doctor's order for a blood draw with a KTO, she will ask the prescribing physician: Is the KTO being prescribed for: the administration of medication? The injection of a contrast agent? A second blood draw? For each question, there are three possible answers: Yes? No? Maybe? |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Patients assigned a triage score of 3A, 3B, or 4 according to the French triage scale, or 3 or 4 according to the CIMU triage scale, by the triage nurse
- Patients with a blood draw order involving the placement of an occluded catheter
- Age 18 years or older
- Patients who have read and understood the information sheet
- Patients who have given their verbal consent to participate in the study
Key exclusion criteria (8 listed)
- Patients admitted to the emergency department with a pre-existing intravenous line
- Patients treated by the Mobile Emergency and Resuscitation Unit outside the hospital
- Patients with a blocked catheter who did not undergo an initial blood draw
- Patient with known neurocognitive disorders incompatible with informed consent
- Pregnant or breastfeeding woman
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| question for the prescriberOnce the nurse has received the doctor's order for a blood draw with a KTO, she will ask the prescribing physician: Is the KTO being prescribed for: the administration of medication? The injection of a contrast agent? A second blood draw? For each question, there are three possible answers: Yes? No? Maybe? | Other | Questions for the prescriber |
Primary outcome
the proportion of obturator catheters placed improperly
Time frame: day 1
Questions for the prescriber
5 secondary outcomes
Correlation between the physician's final decision and nurse activity
Time frame: day 1
Use of the numerical pain scale during obturator catheter placement
Time frame: at the end of procedure (assessed up to 20 minutes)
Micro-costing analysis
Time frame: at the end of procedure (assessed up to 20 minutes)
Types of intravenous medications administered
Time frame: day 1
Number of orders for obturator catheters
Time frame: day 1
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 May 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
ROUSSEL Mélanie, MD contact
Déborah LEBEDIEFF, MS study chair
University Hospital, Rouen
16 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing question for the prescriber in people with an Initial Order for a Blood Draw and Placement of an IV Line in the Emergency Department, run by University Hospital, Rouen at 16 sites in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 13 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 16 sites in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jessica BORTZMEYER, nurse (02.32.88.89.90 ext. +33, jessica.bortzmeyer@chu-rouen.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
the proportion of obturator catheters placed improperly (time frame: day 1). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 May 2026; AzTrials last refreshed its copy on 31 Oct 2026.