Preventive Oral HealthNCT07585682
Mechanisms Behind Benefits Framing
A study testing Basic dental appointment message, Expanded neutral dental appointment message and Expanded generic benefit dental appointment message in people with Preventive Oral Health, run by University of Chile at 1 site in Chile.
Trial summary
This study evaluates the effectiveness of different message framings used to encourage uptake of preventive dental check-ups. Patients will be randomized to receive one of several WhatsApp messages offering a full preventive dental check-up, which vary in message length and in how the benefits of the check-up are… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Preventive Oral Health
- What is being tested?
- Basic dental appointment message, Expanded neutral dental appointment message and Expanded generic benefit dental appointment message
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100,000 participants
- Where
- 1 siteChile
- Study dates
- 26 Jan 2026to May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients aged 18 and above
- Have a valid mobile phone number that can receive WhatsApp messages, recorded in the hospital network's patient database
- Attended a non-dental medical appointment the day before the intended contact day OR have a non-dental medical appointment within the week after the intended contact day
- Have not been contacted in the past two months about preventive dental checkups
- Have not attended a dental appointment at the hospital network in the past 6 months
- Note: The partnering clinic agreed to run the study until a concurrent experiment registered at NCT07121673 is finished. The investigators aim to reach 100,000 patients by then, but the final sample size will vary depending on the actual outreach efforts by the end of the study period.
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country.
About this study
This study evaluates the effectiveness of different message framings used to encourage uptake of preventive dental check-ups. Patients will be randomized to receive one of several WhatsApp messages offering a full preventive dental check-up, which vary in message length and in how the benefits of the check-up are described.
Read the detailed description
Patients in this trial will be randomized to one of four conditions. In all conditions, patients will receive a WhatsApp message from a clinic network, encouraging them to schedule a preventive dental check-up. The conditions vary in message length and the specificity of the benefits emphasized. Previous pilot studies run by the investigators suggest that adding health- or appearance-related meaning to preventive dental checkup invitation messages may reduce uptake relative to a basic WhatsApp invitation. The present study is designed to replicate this pattern and explore the mechanism(s) underlying this pattern by isolating the role of message length and the references to benefits. Specifically:
- Basic Outreach Message: Patients receive a brief outreach message inviting them to schedule a preventive dental check-up and providing basic information about price and availability.
- Expanded Neutral Outreach Message: Patients receive a longer outreach message matched in length to the benefit-focused messages (see below), which adds only neutral wording to the Basic Outreach Message without introducing any additional information.
- Expanded Generic Benefit Outreach Message: Patients receive a longer outreach message that emphasizes general benefits from a preventive dental check-up, without referencing specific outcomes related to dental health or appearance.
- Expanded Specific Benefit Outreach Message: Patients receive a longer outreach message that highlights specific benefits of a preventive dental check-up. Within this condition, patients are further randomly assigned to receive one of four message variants that independently vary (1) whether the benefit emphasized relates to dental health or appearance and (2) whether the benefit is framed as occurring immediately or in the long term.
The researchers primarily ask the following research question: Does emphasizing specific benefits in an expanded outreach message affect dental check-up uptake relative to a basic outreach message? The researchers hypothesize that patients receiving the Expanded Specific Benefit Outreach Message will have lower uptake of dental checkups than patients receiving the Basic Outreach Message. The investigators will also assess the roles of message length and language referencing benefits.
Analysis:
The investigators will run ordinary least squares regressions (OLS) with robust standard errors to predict outcome variables.
- To test whether emphasizing specific benefits in an expanded outreach message affect uptake relative to a basic outreach message, the investigators will pool (collapse) the four variants of the Expanded Specific Benefit Outreach Message condition into a single treatment indicator and compare outcomes for patients assigned to this pooled condition versus patients assigned to the Basic Outreach Message condition. In addition, the investigators will estimate a model that includes indicators for each of the four specific-benefit variants and conduct a joint F-test of whether the four variant indicators are jointly equal (i.e., whether outcomes differ across the variants).
- The investigators will conduct additional comparisons to understand why the Expanded Specific Benefit Outreach message may reduce uptake relative to the Basic Outreach message. Specifically, the investigators will compare outcomes between the Basic Outreach Message condition versus the Expanded Neutral Outreach Message condition to assess the role of message length. If there is no significant difference between the two treatments, they will be pooled and compared to the Specific Benefit (pooled) treatments. Then the investigators will compare outcomes between the Basic Outreach Message condition versus the Expanded Generic Benefit Outreach Message condition to assess the role of message length and language referencing benefits.
These regressions will be run with and without control variables. Control variables include:
- Time fixed effects (since patients will be enrolled into the trial over time)
- Participant age
- Participant gender (male, female, other/unknown)
- Whether patients had had at least one dental visit at this hospital in the past
- Region or clinic indicators, if available
For robustness, the investigators will conduct logit models as well.
The investigators will examine whether the following factors moderate the differences in uptake between the Expanded Specific Benefit Outreach Message condition and Basic Outreach Message condition:
- Whether the patient had completed any dental visit prior to the experiment (based on the data the hospital can provide)
- Whether the patient had completed any preventive medical exam (e.g., mammogram) prior to the experiment (based on the data the hospital can provide)
- Whether participants attended a non-dental medical appointment the day before contact (vs. have a non-dental medical appointment scheduled after the contact day)
- Number of prior visits to the clinic network that were not for dental purposes (based on the data the hospital can provide) prior to the contact (excluding the visit that some of the participants had the day before the contact)
- Insurance type (public vs. private)
- Patient age
- Patient gender (male vs. female)
For exploratory purposes, the investigators will look at longer time windows (e.g., 90 days) for dental appointment attendance and will also examine behaviors related to the dental appointments (e.g., cancellation, rescheduling, no-show).
- Conditions
- Preventive Oral Health
- Being tested
- Basic dental appointment message, Expanded neutral dental appointment message, Expanded generic benefit dental appointment message, Expanded specific benefit dental appointment message
- Keywords
- Behavioral Science, Text Messages, Patient Outreach
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Basic dental appointment messageBehavioural
Patients receive a short WhatsApp message encouraging them to schedule a preventive dental check-up
Expanded neutral dental appointment messageBehavioural
Patients receive an expanded WhatsApp message encouraging them to schedule a preventive dental check-up, which adds neutral words to the Basic Outreach Message without introducing new information.
Expanded generic benefit dental appointment messageBehavioural
Patients receive an expanded WhatsApp message encouraging them to schedule a preventive dental check-up, emphasizing general benefits of doing so.
Expanded specific benefit dental appointment messageBehavioural
Patients receive one of four expanded WhatsApp messages encouraging them to schedule a preventive dental check-up that highlights specific benefits related to dental health or appearance, with patients randomly assigned to one of the four variants.
| Study group | Role | What they receive |
|---|---|---|
| Basic Outreach Message | Active comparator | Basic dental appointment message Receives: Behavioral: Basic dental appointment message |
| Expanded Neutral Outreach Message | Experimental | Expanded neutral dental appointment message Receives: Behavioral: Expanded neutral dental appointment message |
| Expanded Generic Benefit Outreach Message | Experimental | Expanded generic benefit dental appointment message Receives: Behavioral: Expanded generic benefit dental appointment message |
| Expanded Specific Benefit Outreach Message | Experimental | Expanded specific benefit dental appointment message Receives: Behavioral: Expanded specific benefit dental appointment message |
What is being measured
The primary outcome is the main question the study is designed to answer.
Preventive Dental appointment scheduling
Whether the patient schedules a preventive dental check-up
Measured: Within 7 days of receiving the WhatsApp message
Secondary outcomes (3)
Preventive Dental appointment attendance
Whether the patient attends a preventive dental check-up
Measured: Within 30 days of receiving the WhatsApp message
Interest in scheduling
Whether the patient clicks YES in response to the WhatsApp message
Measured: Within 7 days of receiving the WhatsApp message
Any dental appointment scheduling
Whether the patient schedules any dental appointment (regardless of whether it is preventive or not)
Measured: Within 7 days of receiving the WhatsApp message
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 May 2026
- Study start26 Jan 2026
- Primary completion28 Feb 2026
- Study completionMay 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Preventive Oral HealthStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Care provider
- Enrolment
- 100,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Chile
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07585682
- Sponsor's protocol ID
- Dentistry_Benefits_Mechanisms
- Status last verified
- Jan 2026
- First submitted
- 22 Jan 2026
- Last updated
- 14 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: IPD will not be shared due to restrictions in the data use agreement with the partnering clinic network, which prohibits public dissemination of patient-level data.
Study at a glance
From the registry record, last updated by the sponsor on 14 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Mechanisms Behind Benefits Framing
- ClinicalTrials.gov ID
- NCT07585682
- Acronym / sponsor ID
- Dentistry_Benefits_Mechanisms
- Conditions
- Preventive Oral Health
- Keywords
- Behavioral Science, Text Messages, Patient Outreach
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 100,000 participants (estimated)
- Lead sponsor
- University of ChileUniversity, hospital or other
- Study start
- 26 Jan 2026 (actual)
- Primary completion
- 28 Feb 2026 (actual)
- Study completion
- May 2026 (estimated)
- First posted
- 14 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study evaluates the effectiveness of different message framings used to encourage uptake of preventive dental check-ups. Patients will be randomized to receive one of several WhatsApp messages offering a full preventive dental check-up, which vary in message length and in how the benefits of the check-up are described.
Detailed description
Patients in this trial will be randomized to one of four conditions. In all conditions, patients will receive a WhatsApp message from a clinic network, encouraging them to schedule a preventive dental check-up. The conditions vary in message length and the specificity of the benefits emphasized. Previous pilot studies run by the investigators suggest that adding health- or appearance-related meaning to preventive dental checkup invitation messages may reduce uptake relative to a basic WhatsApp invitation. The present study is designed to replicate this pattern and explore the mechanism(s) underlying this pattern by isolating the role of message length and the references to benefits. Specifically:
- Basic Outreach Message: Patients receive a brief outreach message inviting them to schedule a preventive dental check-up and providing basic information about price and availability.
- Expanded Neutral Outreach Message: Patients receive a longer outreach message matched in length to the benefit-focused messages (see below), which adds only neutral wording to the Basic Outreach Message without introducing any additional information.
- Expanded Generic Benefit Outreach Message: Patients receive a longer outreach message that emphasizes general benefits from a preventive dental check-up, without referencing specific outcomes related to dental health or appearance.
- Expanded Specific Benefit Outreach Message: Patients receive a longer outreach message that highlights specific benefits of a preventive dental check-up. Within this condition, patients are further randomly assigned to receive one of four message variants that independently vary (1) whether the benefit emphasized relates to dental health or appearance and (2) whether the benefit is framed as occurring immediately or in the long term.
The researchers primarily ask the following research question: Does emphasizing specific benefits in an expanded outreach message affect dental check-up uptake relative to a basic outreach message? The researchers hypothesize that patients receiving the Expanded Specific Benefit Outreach Message will have lower uptake of dental checkups than patients receiving the Basic Outreach Message. The investigators will also assess the roles of message length and language referencing benefits.
Analysis:
The investigators will run ordinary least squares regressions (OLS) with robust standard errors to predict outcome variables.
- To test whether emphasizing specific benefits in an expanded outreach message affect uptake relative to a basic outreach message, the investigators will pool (collapse) the four variants of the Expanded Specific Benefit Outreach Message condition into a single treatment indicator and compare outcomes for patients assigned to this pooled condition versus patients assigned to the Basic Outreach Message condition. In addition, the investigators will estimate a model that includes indicators for each of the four specific-benefit variants and conduct a joint F-test of whether the four variant indicators are jointly equal (i.e., whether outcomes differ across the variants).
- The investigators will conduct additional comparisons to understand why the Expanded Specific Benefit Outreach message may reduce uptake relative to the Basic Outreach message. Specifically, the investigators will compare outcomes between the Basic Outreach Message condition versus the Expanded Neutral Outreach Message condition to assess the role of message length. If there is no significant difference between the two treatments, they will be pooled and compared to the Specific Benefit (pooled) treatments. Then the investigators will compare outcomes between the Basic Outreach Message condition versus the Expanded Generic Benefit Outreach Message condition to assess the role of message length and language referencing benefits.
These regressions will be run with and without control variables. Control variables include:
- Time fixed effects (since patients will be enrolled into the trial over time)
- Participant age
- Participant gender (male, female, other/unknown)
- Whether patients had had at least one dental visit at this hospital in the past
- Region or clinic indicators, if available
For robustness, the investigators will conduct logit models as well.
The investigators will examine whether the following factors moderate the differences in uptake between the Expanded Specific Benefit Outreach Message condition and Basic Outreach Message condition:
- Whether the patient had completed any dental visit prior to the experiment (based on the data the hospital can provide)
- Whether the patient had completed any preventive medical exam (e.g., mammogram) prior to the experiment (based on the data the hospital can provide)
- Whether participants attended a non-dental medical appointment the day before contact (vs. have a non-dental medical appointment scheduled after the contact day)
- Number of prior visits to the clinic network that were not for dental purposes (based on the data the hospital can provide) prior to the contact (excluding the visit that some of the participants had the day before the contact)
- Insurance type (public vs. private)
- Patient age
- Patient gender (male vs. female)
For exploratory purposes, the investigators will look at longer time windows (e.g., 90 days) for dental appointment attendance and will also examine behaviors related to the dental appointments (e.g., cancellation, rescheduling, no-show).
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, care provider)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Basic Outreach Message | Active comparator | Behavioral: Basic dental appointment messageBasic dental appointment message |
| Expanded Neutral Outreach Message | Experimental | Behavioral: Expanded neutral dental appointment messageExpanded neutral dental appointment message |
| Expanded Generic Benefit Outreach Message | Experimental | Behavioral: Expanded generic benefit dental appointment messageExpanded generic benefit dental appointment message |
| Expanded Specific Benefit Outreach Message | Experimental | Behavioral: Expanded specific benefit dental appointment messageExpanded specific benefit dental appointment message |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Patients aged 18 and above
- Have a valid mobile phone number that can receive WhatsApp messages, recorded in the hospital network's patient database
- Attended a non-dental medical appointment the day before the intended contact day OR have a non-dental medical appointment within the week after the intended contact day
- Have not been contacted in the past two months about preventive dental checkups
- Have not attended a dental appointment at the hospital network in the past 6 months
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Basic dental appointment messagePatients receive a short WhatsApp message encouraging them to schedule a preventive dental check-up | Behavioural | Basic Outreach Message |
| Expanded neutral dental appointment messagePatients receive an expanded WhatsApp message encouraging them to schedule a preventive dental check-up, which adds neutral words to the Basic Outreach Message without introducing new information. | Behavioural | Expanded Neutral Outreach Message |
| Expanded generic benefit dental appointment messagePatients receive an expanded WhatsApp message encouraging them to schedule a preventive dental check-up, emphasizing general benefits of doing so. | Behavioural | Expanded Generic Benefit Outreach Message |
| Expanded specific benefit dental appointment messagePatients receive one of four expanded WhatsApp messages encouraging them to schedule a preventive dental check-up that highlights specific benefits related to dental health or appearance, with patients randomly assigned to one of the four variants. | Behavioural | Expanded Specific Benefit Outreach Message |
Primary outcome
Preventive Dental appointment scheduling
Time frame: Within 7 days of receiving the WhatsApp message
Whether the patient schedules a preventive dental check-up
3 secondary outcomes
Preventive Dental appointment attendance
Time frame: Within 30 days of receiving the WhatsApp message
Interest in scheduling
Time frame: Within 7 days of receiving the WhatsApp message
Any dental appointment scheduling
Time frame: Within 7 days of receiving the WhatsApp message
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 May 2026.
- Individual participant dataSharing planned: No. IPD will not be shared due to restrictions in the data use agreement with the partnering clinic network, which prohibits public dissemination of patient-level data.
Related trials for Preventive Oral Health
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Assessing the Impact of a Social Media-Based Educational Intervention Using WhatsApp Video Messages on Dental Caries Prevention Knowledge, Oral Hygiene Practices, and Attitudes Toward Dental Health Among Primary School Children Aged 10-12 Years in Public Schools in Cairo Governorate, Egypt: A Quasi-
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Basic dental appointment message, Expanded neutral dental appointment message and Expanded generic benefit dental appointment message in people with Preventive Oral Health, run by University of Chile at 1 site in Chile.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 14 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Chile. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Preventive Dental appointment scheduling (time frame: Within 7 days of receiving the WhatsApp message). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 May 2026.