tDCSNCT07592559
tDCS and the Gaze Cueing Effect
A study testing Gaze cues, Arrow cues and SOA 200 ms in people with tDCS and Cues Type, run by University of Electronic Science and Technology of China at 1 site in China.
Trial summary
This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues. Read more about this study
- Who is it for?
- Ages 18 to 30 yearsHealthy volunteers can take part
- What is being tested?
- Gaze cues, Arrow cues and SOA 200 ms
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 60 participants
- Where
- 1 siteChina
- Study dates
- 2 Jun 2022to 8 Dec 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- healthy subjects without past or current psychiatric or neurological disorders
Who cannot join
- history of head injury
- no implants in the head
- medical or psychiatric illness.
Trial locations and contacts
1 site in 1 country.
China1 site
School of Foreign Languages, University of Electronic Science and Technology of China
Chengdu, Sichuan, 611731
About this study
Official title: Influence of Transcranial Direct Current Stimulation Applied to the Right Orbitofrontal Cortex on Gaze and Arrow Cueing Effects
This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.
Read the detailed description
This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.To examine the distinct functions of the OFC in processing social versus non-social stimuli, participants were randomly assigned to one of three tDCS groups: anodal, cathodal, or sham. Following stimulation, all participants completed a spatial cueing task involving both gaze and arrow cues. Two stimulus onset asynchrony (SOA) conditions (200 ms and 600 ms) were implemented to investigate how timing modulates the processing of these cues within the rOFC.
- Conditions
- tDCS, Cues Type, SOA, Congruency
- Being tested
- Gaze cues, Arrow cues, SOA 200 ms, SOA 600 ms, Congruent
- Keywords
- transcranial direct current stimulation, gaze cueing effect, orbitofrontal cortex
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gaze cuesBehavioural
use eye gaze images as cues
Arrow cuesBehavioural
use arrow images as cues
SOA 200 msBehavioural
The stimulus onset asynchrony (SOA) between the cue and the target was 200 ms.
SOA 600 msBehavioural
The stimulus onset asynchrony (SOA) between the cue and the target was 600 ms.
CongruentBehavioural
The cue is spatially congruent with the target.
IncongruentBehavioural
The cue is spatially incongruent with the target.
| Study group | Role | What they receive |
|---|---|---|
| anodal tDCS | Experimental | anodal tDCS rOFC Receives: Behavioral: Gaze cues; Behavioral: Arrow cues; Behavioral: SOA 200 ms; Behavioral: SOA 600 ms; Behavioral: Congruent; Behavioral: Incongruent |
| cathodal tDCS | Experimental | cathodal tDCS rOFC Receives: Behavioral: Gaze cues; Behavioral: Arrow cues; Behavioral: SOA 200 ms; Behavioral: SOA 600 ms; Behavioral: Congruent; Behavioral: Incongruent |
| sham tDCS | Sham comparator | sham tDCS rOFC Receives: Behavioral: Gaze cues; Behavioral: Arrow cues; Behavioral: SOA 200 ms; Behavioral: SOA 600 ms; Behavioral: Congruent; Behavioral: Incongruent |
What is being measured
The primary outcome is the main question the study is designed to answer.
Reaction time to the judgment of the target location.
The primary analysis focused on the reaction times for judging the target location under each condition.
Measured: 1 hour
Secondary outcomes (1)
Magnitude of the cueing effect
This index is derived by subtracting the congruent reaction time from the incongruent reaction time to quantify the magnitude of the cueing effect.
Measured: 1 hour
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 May 2026
- Study start2 Jun 2022
- Primary completion30 Oct 2022
- Study completion8 Dec 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for tDCSStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Electronic Science and Technology of China
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Shan Gao, University of Electronic Science and Technology of China
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07592559
- Sponsor's protocol ID
- UESTC-GazeLab-01
- Status last verified
- May 2026
- First submitted
- 23 Apr 2026
- Last updated
- 18 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 18 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of Transcranial Direct Current Stimulation Applied to the Right Orbitofrontal Cortex on Gaze and Arrow Cueing Effects
- ClinicalTrials.gov ID
- NCT07592559
- Acronym / sponsor ID
- UESTC-GazeLab-01
- Conditions
- tDCS, Cues Type, SOA, Congruency
- Keywords
- transcranial direct current stimulation, gaze cueing effect, orbitofrontal cortex
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- University of Electronic Science and Technology of ChinaUniversity, hospital or other
- Study start
- 2 Jun 2022 (actual)
- Primary completion
- 30 Oct 2022 (actual)
- Study completion
- 8 Dec 2022 (actual)
- First posted
- 18 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.
Detailed description
This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.To examine the distinct functions of the OFC in processing social versus non-social stimuli, participants were randomly assigned to one of three tDCS groups: anodal, cathodal, or sham. Following stimulation, all participants completed a spatial cueing task involving both gaze and arrow cues. Two stimulus onset asynchrony (SOA) conditions (200 ms and 600 ms) were implemented to investigate how timing modulates the processing of these cues within the rOFC.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| anodal tDCS | Experimental | Behavioral: Gaze cues, Behavioral: Arrow cues, Behavioral: SOA 200 ms, Behavioral: SOA 600 ms, Behavioral: Congruent, Behavioral: Incongruentanodal tDCS rOFC |
| cathodal tDCS | Experimental | Behavioral: Gaze cues, Behavioral: Arrow cues, Behavioral: SOA 200 ms, Behavioral: SOA 600 ms, Behavioral: Congruent, Behavioral: Incongruentcathodal tDCS rOFC |
| sham tDCS | Sham comparator | Behavioral: Gaze cues, Behavioral: Arrow cues, Behavioral: SOA 200 ms, Behavioral: SOA 600 ms, Behavioral: Congruent, Behavioral: Incongruentsham tDCS rOFC |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- healthy subjects without past or current psychiatric or neurological disorders
Key exclusion criteria (3 listed)
- history of head injury
- no implants in the head
- medical or psychiatric illness.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gaze cuesuse eye gaze images as cues | Behavioural | anodal tDCS, cathodal tDCS, sham tDCS |
| Arrow cuesuse arrow images as cues | Behavioural | anodal tDCS, cathodal tDCS, sham tDCS |
| SOA 200 msThe stimulus onset asynchrony (SOA) between the cue and the target was 200 ms. | Behavioural | anodal tDCS, cathodal tDCS, sham tDCS |
| SOA 600 msThe stimulus onset asynchrony (SOA) between the cue and the target was 600 ms. | Behavioural | anodal tDCS, cathodal tDCS, sham tDCS |
| CongruentThe cue is spatially congruent with the target. | Behavioural | anodal tDCS, cathodal tDCS, sham tDCS |
| IncongruentThe cue is spatially incongruent with the target. | Behavioural | anodal tDCS, cathodal tDCS, sham tDCS |
Primary outcome
Reaction time to the judgment of the target location.
Time frame: 1 hour
The primary analysis focused on the reaction times for judging the target location under each condition.
1 secondary outcome
Magnitude of the cueing effect
Time frame: 1 hour
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 May 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gaze cues, Arrow cues and SOA 200 ms in people with tDCS and Cues Type, run by University of Electronic Science and Technology of China at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Reaction time to the judgment of the target location. (time frame: 1 hour). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 May 2026.