Kidney TransplantMediTNCT07592624
Evaluation of an Instructional Video About Medication Management During Admission and Medication Adherence for Kidney Transplantation and in the Outpatient Clinic in a Dutch University Hospital.
A study testing Instructional video about medication administration in people with Kidney Transplant and Adult, run by Erasmus Medical Center at 1 site in Netherlands.
Trial summary
The goal of this RCT is to evaluate the effect of the instructional video on improving patient compliance and reducing medication errors. The study will include adult kidney transplant recipients (18 years or older) at Erasmus MC who have undergone a kidney transplantation starting January 2026. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Kidney Transplant, Adult, Medication Adherence
- What is being tested?
- Instructional video about medication administration
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 308 participants
- Where
- 1 siteNetherlands
- Study dates
- 1 Jan 2027to 31 Dec 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- The patient is able to take the medication independently or with the help of someone else (professionals not included).
- After admission, the patient is discharged to their own home or home of friend/relative.
- The patient had a follow up at the outpatient clinic in the Erasmus Medical Center for at least one year after transplantation.
- The patient is able to read the medication list or an illiteracy-friendly medication list.
Who cannot join
- Patients under 18 years of age
- Patients who got discharged with a medication dispenser
- Refusal to participate in the study.
- Cognitive impairments that hinder participation.
- Patients and/or family who can not understand (language barrier) the instructional video.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Netherlands1 site
Erasmus Medical Center
Rotterdam, 3015GD
Myrthe van der Zanden, MSc, Drs., +31650094899, m.vanderzanden@erasmusmc.nl
About this study
The goal of this RCT is to evaluate the effect of the instructional video on improving patient compliance and reducing medication errors. The study will include adult kidney transplant recipients (18 years or older) at Erasmus MC who have undergone a kidney transplantation starting January 2026.
The main questions it aims to answer:
Read more
The primary aim of this study is to assess whether our developed video instruction, compared with the traditional verbal instruction, both of which are given shortly before training during admission, reduces the number of medication errors in kidney transplant patients.
The study will also examine the correlation between patient characteristics (such as age, comorbidities, and language proficiency) and medication errors. Additionally, patient-reported medication errors will be measured through a questionnaire completed during follow-up visits at the outpatient clinic, which is part of standard care.
The instructional video will be evaluated by a short questionnaire.
- Conditions
- Kidney Transplant, Adult, Medication Adherence, Instruction Videos
- Being tested
- Instructional video about medication administration
- Medical subject headings
- Medication Adherence
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Instructional video about medication administrationOther
Self developed instructional video for a Dutch university hospital, for Dutch kidney transplant patients. Instructional video is about medication administration during admission.
| Study group | Role | What they receive |
|---|---|---|
| Verbal instruction | No intervention | Patients receive the verbal instruction about medication training from the nurses. |
| Video instruction | Experimental | Patients receive the instruction video about medication training from the nurses. Receives: Other: Instructional video about medication administration |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence and type of medication errors during admission
The primary outcome of this study will be the incidence (number of medication errors) and type of medication errors ( 1)Medication preparation omitted, 2) Incorrect dosage, 3) Incorrect administration at the scheduled time, 4), Medication discontinued inappropriately, 5)Error not documented by the nurse) during admission, evaluated through direct observation by healthcare providers. These errors will be documented and reported via patient portals by nurses.
Measured: During admission
Secondary outcomes (3)
Patient characteristics
Age (in years), gender (male/female/nonbinair), country of origin, language proficiency, number of previous organ transplantations, donor type of the kidney transplant (DCD, DBD, Living), and renal replacement therapy (HD/PD/Pre-emptive).
Measured: During admission
Evaluation of the instructional video
Structured questionnaire with the following questions:
- Was the instructional video clear and easy to understand? (open answer)
- Did you find the instructional video easy to follow? (open answer)
- Do you have any suggestions for improvements? (open answer)
Measured: At the end of admission
BAASIS
Participants will complete a patient-reported questionnaire (BAASIS) every three months during the first year after transplantation. The questionnaire consists of five yes/no questions related to medication errors occurring in the home setting. The questions will ask whether the participant has:
- Forgotten to take their medication, (yes/no)
- Taken the wrong dose of medication, (yes/no)
- Taken medication at the wrong time, (yes/no)
- Mixed up medications, (yes/no)
- Not taken their medication due to confusion or difficulty. (yes/no)
The goal is to evaluate whether there is a reduction in home-reported medication errors for those who receive a different medication management training method in the hospital.
Measured: During the first year follow up at the out patient clinic after kidney transplantation in the Erasmus MC
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 May 2026
- Study start1 Jan 2027 (estimated)
- Primary completion1 Jan 2029 (estimated)
- Study completion31 Dec 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Kidney TransplantStudies of the same condition, open and under way.
- More trials run by Erasmus Medical CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 308 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Erasmus Medical Center
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Jacqueline van de Wetering, Erasmus Medical Center
- Investigators
- Jacqueline van de Wetering, MD, Dr., Study chair, Erasmus Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07592624
- Sponsor's protocol ID
- 14372
- Acronym
- MediT
- Status last verified
- May 2026
- First submitted
- 12 Mar 2026
- Last updated
- 16 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 16 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of an Instructional Video About Medication Management During Admission and Medication Adherence for Kidney Transplantation and in the Outpatient Clinic in a Dutch University Hospital.
- ClinicalTrials.gov ID
- NCT07592624
- Acronym / sponsor ID
- MediT / 14372
- Conditions
- Kidney Transplant, Adult, Medication Adherence, Instruction Videos
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 308 participants (estimated)
- Lead sponsor
- Erasmus Medical CenterUniversity, hospital or other
- Study start
- 1 Jan 2027 (estimated)
- Primary completion
- 1 Jan 2029 (estimated)
- Study completion
- 31 Dec 2029 (estimated)
- First posted
- 18 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this RCT is to evaluate the effect of the instructional video on improving patient compliance and reducing medication errors. The study will include adult kidney transplant recipients (18 years or older) at Erasmus MC who have undergone a kidney transplantation starting January 2026.
The main questions it aims to answer:
The primary aim of this study is to assess whether our developed video instruction, compared with the traditional verbal instruction, both of which are given shortly before training during admission, reduces the number of medication errors in kidney transplant patients.
The study will also examine the correlation between patient characteristics (such as age, comorbidities, and language proficiency) and medication errors. Additionally, patient-reported medication errors will be measured through a questionnaire completed during follow-up visits at the outpatient clinic, which is part of standard care.
The instructional video will be evaluated by a short questionnaire.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Verbal instruction | No intervention | –Patients receive the verbal instruction about medication training from the nurses. |
| Video instruction | Experimental | Other: Instructional video about medication administrationPatients receive the instruction video about medication training from the nurses. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- The patient is able to take the medication independently or with the help of someone else (professionals not included).
- After admission, the patient is discharged to their own home or home of friend/relative.
- The patient had a follow up at the outpatient clinic in the Erasmus Medical Center for at least one year after transplantation.
- The patient is able to read the medication list or an illiteracy-friendly medication list.
Key exclusion criteria (5 listed)
- Patients under 18 years of age
- Patients who got discharged with a medication dispenser
- Refusal to participate in the study.
- Cognitive impairments that hinder participation.
- Patients and/or family who can not understand (language barrier) the instructional video.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Instructional video about medication administrationSelf developed instructional video for a Dutch university hospital, for Dutch kidney transplant patients. Instructional video is about medication administration during admission. | Other | Video instruction |
Primary outcome
Incidence and type of medication errors during admission
Time frame: During admission
The primary outcome of this study will be the incidence (number of medication errors) and type of medication errors ( 1)Medication preparation omitted, 2) Incorrect dosage, 3) Incorrect administration at the scheduled time, 4), Medication discontinued inappropriately, 5)Error not documented by the nurse) during admission, evaluated through direct observation by healthcare providers. These errors will be documented and reported via patient portals by nurses.
3 secondary outcomes
Patient characteristics
Time frame: During admission
Evaluation of the instructional video
Time frame: At the end of admission
BAASIS
Time frame: During the first year follow up at the out patient clinic after kidney transplantation in the Erasmus MC
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Sep 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Jacqueline van de Wetering, MD, Dr. study chair
Erasmus Medical Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Instructional video about medication administration in people with Kidney Transplant and Adult, run by Erasmus Medical Center at 1 site in Netherlands.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 16 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Myrthe van der Zanden, MSc, Drs (+31650094899, m.vanderzanden@erasmusmc.nl), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence and type of medication errors during admission (time frame: During admission). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Sep 2026; AzTrials last refreshed its copy on 26 Oct 2026.