Arterial HypertensionNCT07593768
Clinical and Prognostic Significance of Periodontitis in Patients With Arterial Hypertension
An observational study of Arterial Hypertension and Periodontitis, run by I.M. Sechenov First Moscow State Medical University at 1 site in Russia.
Trial summary
As part of a prospective study, to evaluate the effect of periodontitis on the course of hypertension at baseline, during 6 and 12 months Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Arterial Hypertension, Periodontitis
- What is being tested?
- Orthopantomography
- How many people
- 200 participants
- Where
- 1 siteRussia
- Study dates
- 10 Oct 2023to 30 May 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The study is set to include 200 patients (both sexes) over 18 years of age with arterial hypertension who signed the informed consent form for participation in the study: 100 patients with periodontitis and 100 patients without periodontitis - control group
Who may be able to join
- Age (18 years and older)
- Written informed consent signed
Who cannot join
- Failure to follow up
Trial locations and contacts
1 site in 1 country.
About this study
As part of a prospective study, to evaluate the effect of periodontitis on the course of hypertension at baseline, during 6 and 12 months
Read the detailed description
The study focuses on following tasks: to evaluate and compare arterial stiffness in patients with hypertension and the control group, the effect of treatment and control of clinical manifestations of periodontitis in patients with hypertension and the control group, the effect of treatment and control of clinical manifestations of periodontitis on the level of CRP in patients with hypertension and the control group, the effect of periodontitis control on the dynamics of OH, LDL, TG, uric acid, and fasting glycemia levels, the effect of periodontitis on the risk of atrial fibrillation/flutter in patients with arterial hypertension, to develop an information platform for patients with periodontitis for early detection of CVD risks and control of modifiable risk factors
- Conditions
- Arterial Hypertension, Periodontitis
- Being tested
- Orthopantomography
- Keywords
- cardiovascular risk, arterial hypertension, inflammation, periodontitis
- Medical subject headings
- Hypertension, Periodontitis, Inflammation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
OrthopantomographyDiagnostic test
Orthopantomography
| Study group | Role | What they receive |
|---|---|---|
| Periodontitis group | Not described Receives: Diagnostic Test: Orthopantomography | |
| Control group | Not described Receives: Diagnostic Test: Orthopantomography |
What is being measured
The primary outcome is the main question the study is designed to answer.
Triglyceride level
Triglyceride level
Measured: 12 months from inclusion
Low density lipoprotein level
Low density lipoprotein level
Measured: 12 months from inclusion
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 May 2026
- Study start10 Oct 2023
- Primary completion1 Sep 2025
- Study completion30 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Arterial HypertensionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- I.M. Sechenov First Moscow State Medical University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Olga Trushina, MD, PhD, Principal investigator, Sechenov University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07593768
- Sponsor's protocol ID
- 19-23
- Status last verified
- May 2026
- First submitted
- 12 May 2026
- Last updated
- 18 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical and Prognostic Significance of Periodontitis in Patients With Arterial Hypertension
- ClinicalTrials.gov ID
- NCT07593768
- Acronym / sponsor ID
- 19-23
- Conditions
- Arterial Hypertension, Periodontitis
- Keywords
- cardiovascular risk, arterial hypertension, inflammation, periodontitis
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- I.M. Sechenov First Moscow State Medical UniversityUniversity, hospital or other
- Study start
- 10 Oct 2023 (actual)
- Primary completion
- 1 Sep 2025 (actual)
- Study completion
- 30 May 2026 (estimated)
- First posted
- 18 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
As part of a prospective study, to evaluate the effect of periodontitis on the course of hypertension at baseline, during 6 and 12 months
Detailed description
The study focuses on following tasks: to evaluate and compare arterial stiffness in patients with hypertension and the control group, the effect of treatment and control of clinical manifestations of periodontitis in patients with hypertension and the control group, the effect of treatment and control of clinical manifestations of periodontitis on the level of CRP in patients with hypertension and the control group, the effect of periodontitis control on the dynamics of OH, LDL, TG, uric acid, and fasting glycemia levels, the effect of periodontitis on the risk of atrial fibrillation/flutter in patients with arterial hypertension, to develop an information platform for patients with periodontitis for early detection of CVD risks and control of modifiable risk factors
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Periodontitis group | – | Diagnostic Test: Orthopantomography |
| Control group | – | Diagnostic Test: Orthopantomography |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The study is set to include 200 patients (both sexes) over 18 years of age with arterial hypertension who signed the informed consent form for participation in the study: 100 patients with periodontitis and 100 patients without periodontitis - control group
Key inclusion criteria (2 listed)
- Age (18 years and older)
- Written informed consent signed
Key exclusion criteria (1 listed)
- Failure to follow up
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| OrthopantomographyOrthopantomography | Diagnostic test | Control group, Periodontitis group |
Primary outcome
Triglyceride level
Time frame: 12 months from inclusion
Triglyceride level
Low density lipoprotein level
Time frame: 12 months from inclusion
Low density lipoprotein level
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Olga Trushina, MD, PhD principal investigator
Sechenov University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Arterial Hypertension and Periodontitis, run by I.M. Sechenov First Moscow State Medical University at 1 site in Russia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 18 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Russia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Triglyceride level (time frame: 12 months from inclusion). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 May 2026.