DysphagiaSINGSNCT07595315
Foundations for Prescribing Song-Based Therapies: A Quantitative Comparison of Laryngeal Exercises
A study testing Dysphagia Treatment Protocol in people with Dysphagia, run by University of Kansas Medical Center.
Trial summary
SINGS explores the therapeutic potential of song-based exercises for treating dysphagia in geriatric populations. The project aims to compare the effectiveness of song-based tasks with traditional speech-language pathology (SLP) exercises using advanced tools such as surface electromyography (sEMG) and functional… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Dysphagia
- What is being tested?
- Dysphagia Treatment Protocol
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 0 participants
- Where
- No sites listed yet
- Study dates
- 1 Jun 2025to 15 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Healthy Adults
Who cannot join
- History of head and neck cancer, radiation to the neck, and/or other head and neck based surgeries*
- Formal Dysphagia diagnosis*
- Formal GERD diagnosis*
- Adults unable to consent
- Individuals who are not yet adults (infants, children, teenagers)
- Prisoners
About this study
SINGS explores the therapeutic potential of song-based exercises for treating dysphagia in geriatric populations. The project aims to compare the effectiveness of song-based tasks with traditional speech-language pathology (SLP) exercises using advanced tools such as surface electromyography (sEMG) and functional neuroimaging. In addition to quantifying functional activity during therapy, the study will assess patient compliance, satisfaction, and long-term swallowing outcomes, with a focus on improving quality of life through innovative, enjoyable therapies.
- Conditions
- Dysphagia
- Being tested
- Dysphagia Treatment Protocol
- Keywords
- Song-based therapy, Music therapy, Surface EMG, EEG
- Medical subject headings
- Deglutition Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dysphagia Treatment ProtocolOther
Also called SINGS
The SINGS arm will be completed by all members in the cohort.
| Study group | Role | What they receive |
|---|---|---|
| Healthy cohort without prescribed dysphagia | Placebo comparator | This cohort of healthy individuals will help establish mechanisms of therapy protocols to apply in future studies on target population. Receives: Other: Dysphagia Treatment Protocol |
| SINGS Intervention | Experimental | The SINGS arm will be completed by all members in the cohort. Receives: Other: Dysphagia Treatment Protocol |
What is being measured
The primary outcome is the main question the study is designed to answer.
Muscle Activation
Surface EMG readings between SBT and SLP tasks.
Measured: Day 1 (single 90-minute study visit)
EEG
Similar regional neural activity measured by EEG between SBT and SLP tasks.
Measured: Day 1 (single 90-minute study visit)
Secondary outcomes (3)
EAT-10 Total Score
Total score on the Eating Assessment Tool (EAT-10) questionnaire
Measured: Day 1 (single study visit)
Self-reported tobacco and e-cigarette use
Self-reported tobacco and e-cigarette use variables (e.g., days used in past 30 days; cigarettes per day; quit attempts; age of initiation)
Measured: Day 1 (single study visit); assesses past 30 days and lifetime history as applicable
Patient Satisfaction Survey
Likert-scale responses (1-5) on satisfaction, convenience, enjoyment, ease, and confidence comparing song-based tasks to SLP tasks
Measured: Day 1 (single study visit)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 May 2026
- Study start1 Jun 2025 (estimated)
- Primary completion15 Oct 2025 (estimated)
- Study completion15 Dec 2025 (estimated)
Why it stopped: Unable to provide clinical time needed to complete trail duties.
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for DysphagiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Single group
- Model description
- Participants are prospectively assigned to perform predefined speech-language pathology exercises and song-based tasks during a single study visit while EEG and surface EMG are recorded for mechanistic comparison. This is a basic science / physiologic study conducted in healthy adults with a cross-sectional, single-visit (\~90 minutes) design.
- Masking
- None (open label)
- Enrolment
- 0 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Kansas Medical Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Center for Advancing Translational Sciences (NCATS)
- Responsible party
- Sponsor
- Investigators
- Jennifer Villwock, MD, Principal investigator, University of Kansas Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07595315
- Sponsor's protocol ID
- SINGS TL1
- Other IDs
- TL1TR002368
- Acronym
- SINGS
- Status last verified
- May 2026
- First submitted
- 20 Nov 2024
- Last updated
- 19 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: It is not yet known if there will be a plan to make IPD available.
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Foundations for Prescribing Song-Based Therapies: A Quantitative Comparison of Laryngeal Exercises
- ClinicalTrials.gov ID
- NCT07595315
- Acronym / sponsor ID
- SINGS / SINGS TL1
- Conditions
- Dysphagia
- Keywords
- Song-based therapy, Music therapy, Surface EMG, EEG
- Study type
- Interventional
- Recruitment status
- WithdrawnReason stopped: Unable to provide clinical time needed to complete trail duties.
- Enrolment
- 0 participants (actual)
- Lead sponsor
- University of Kansas Medical CenterUniversity, hospital or other
- Collaborators
- National Center for Advancing Translational Sciences (NCATS)
- Study start
- 1 Jun 2025 (estimated)
- Primary completion
- 15 Oct 2025 (estimated)
- Study completion
- 15 Dec 2025 (estimated)
- First posted
- 19 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
SINGS explores the therapeutic potential of song-based exercises for treating dysphagia in geriatric populations. The project aims to compare the effectiveness of song-based tasks with traditional speech-language pathology (SLP) exercises using advanced tools such as surface electromyography (sEMG) and functional neuroimaging. In addition to quantifying functional activity during therapy, the study will assess patient compliance, satisfaction, and long-term swallowing outcomes, with a focus on improving quality of life through innovative, enjoyable therapies.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants are prospectively assigned to perform predefined speech-language pathology exercises and song-based tasks during a single study visit while EEG and surface EMG are recorded for mechanistic comparison. This is a basic science / physiologic study conducted in healthy adults with a cross-sectional, single-visit (~90 minutes) design.
| Arm | Type | Receives |
|---|---|---|
| Healthy cohort without prescribed dysphagia | Placebo comparator | Other: Dysphagia Treatment ProtocolThis cohort of healthy individuals will help establish mechanisms of therapy protocols to apply in future studies on target population. |
| SINGS Intervention | Experimental | Other: Dysphagia Treatment ProtocolThe SINGS arm will be completed by all members in the cohort. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Healthy Adults
Key exclusion criteria (6 listed)
- History of head and neck cancer, radiation to the neck, and/or other head and neck based surgeries*
- Formal Dysphagia diagnosis*
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dysphagia Treatment ProtocolAlso: SINGSThe SINGS arm will be completed by all members in the cohort. | Other | Healthy cohort without prescribed dysphagia, SINGS Intervention |
Primary outcome
Muscle Activation
Time frame: Day 1 (single 90-minute study visit)
Surface EMG readings between SBT and SLP tasks.
EEG
Time frame: Day 1 (single 90-minute study visit)
Similar regional neural activity measured by EEG between SBT and SLP tasks.
3 secondary outcomes
EAT-10 Total Score
Time frame: Day 1 (single study visit)
Self-reported tobacco and e-cigarette use
Time frame: Day 1 (single study visit); assesses past 30 days and lifetime history as applicable
Patient Satisfaction Survey
Time frame: Day 1 (single study visit)
Results and safety
The study was withdrawn before enrolling participants, so there are no results.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- Individual participant dataSharing planned: Undecided. It is not yet known if there will be a plan to make IPD available.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Jennifer Villwock, MD principal investigator
University of Kansas Medical Center
Questions about this trial
What is this clinical trial studying?
A study testing Dysphagia Treatment Protocol in people with Dysphagia, run by University of Kansas Medical Center.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: withdrawn, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was withdrawn before enrolling participants, so there are no results.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Muscle Activation (time frame: Day 1 (single 90-minute study visit)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.