AgedNCT07596082
Development of a Chatbot-supported Personalized Exercise Program for Older Adults and Evaluation of Its Effects on Cognitive Functions
A study testing Artificial intelligence-supported chatbot in people with Aged and Exercise, run by Dokuz Eylul University at 1 site in Turkey (Türkiye).
Trial summary
The purpose of this study is to develop an artificial intelligence-based chatbot application to support exercise behavior in individuals aged 60 and over who do not regularly exercise, and to evaluate its effectiveness. Read more about this study
- Who is it for?
- Ages 65 years and olderHealthy volunteers can take part
- What is being tested?
- Artificial intelligence-supported chatbot
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Aug 2026to 30 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- Healthy volunteers accepted
- Older adult
Who may be able to join
- Aged 65 years and older
- Normal or mildly impaired cognitive status
- Medical condition that does not prevent participation in physical activity
- Ability to use a smartphone or tablet (for chatbot access)
- Voluntary participation
Who cannot join
- Moderate to severe dementia
- Severe depression or serious psychiatric disorders
- Acute cardiovascular risk
- Communication difficulties due to significant hearing or visual impairment
- Regular engagement in structured exercise within the past 6 months (participants in the maintenance phase of exercise behavior)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Dokuz Eylul University Faculty of Medicine Department of Family Medicine
Izmir
About this study
The purpose of this study is to develop an artificial intelligence-based chatbot application to support exercise behavior in individuals aged 60 and over who do not regularly exercise, and to evaluate its effectiveness. In addition, the study aims to examine the effects of changes in exercise habits on the cognitive (mental) functions of older adults.
In this study, the impact of a chatbot-supported personalized exercise program on cognitive functions in older individuals will be evaluated. A total of 90 participants is planned for inclusion in this study.
Read more
If you agree to participate in this study, depending on the group you are assigned to, you may receive:
- An artificial intelligence-based chatbot program, along with educational materials about the importance of exercise, or
- Only educational materials (brochures) prepared by the researchers about the importance of exercise.
At the beginning of the study, you will be asked to complete a data collection form. The same form will also be administered at week 12 and week 24.
This form will include:
- Basic information such as your age and gender,
- Questions about your exercise habits,
- A brief test to assess your cognitive (mental) functions,
- Questions evaluating your level of physical activity. The study duration is 24 weeks, including 12 weeks of intervention and 12 weeks of follow-up.
- Conditions
- Aged, Exercise, Cognition, Artificial Intelligence (AI), Health Behavior
- Being tested
- Artificial intelligence-supported chatbot
- Medical subject headings
- Motor Activity, Health Behavior
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Artificial intelligence-supported chatbotBehavioural
Participants will receive a combined behavioral intervention of an educational brochure developed by the Ministry of Health and access to an artificial intelligence (AI)-supported chatbot designed to promote physical activity.
The brochure will provide standardized written information on the importance of exercise, including general recommendations, health benefits, and basic guidance for an active lifestyle.
Participants will also have access to an AI-supported chatbot throughout the intervention period. The chatbot will deliver automated, interactive messages to increase physical activity, including motivational prompts, educational reinforcement, and behavior-change support.
The intervention will be delivered digitally via the chatbot platform, with no medication or physical devices required. The total duration and frequency of chatbot interactions will be continuous and on-demand during the study period.
| Study group | Role | What they receive |
|---|---|---|
| Artificial intelligence-supported chatbot and educational brochure on the importance of exercise | Experimental | Participants assigned to this arm will receive a combined digital and educational intervention designed to promote behavior change in physical activity. In addition to a standard researcher-developed informational brochure describing the health benefits of exercise, participants will have access to a chatbot supported by artificial intelligence technology.
The chatbot will provide:
* Interactive, on-demand communication regarding physical activity and exercise
* Personalized educational messages tailored to participant needs and engagement patterns
* Motivational support and behavioral prompts to encourage adherence to physical activity recommendations
The brochure will provide standardized, non-interactive information on:
* The importance and health benefits of regular exercise
* General physical activity recommendations This intervention arm differs from comparator arms by incorporating an interactive, adaptive, and continuous AI-based support system. Receives: Behavioral: Artificial intelligence-supported chatbot |
| Control (Brochure Only) Group | No intervention | Participants assigned to this arm will receive a standard researcher-developed informational brochure on the importance of exercise, but will not receive any digital or interactive intervention. The brochure will provide standardized, non-interactive information on: * The importance and health benefits of regular exercise * General physical activity recommendations In addition to receiving the brochure, participants will: * Continue their usual daily activities and routine care * Do not have access to the artificial intelligence-supported chatbot * Not receive any personalized, interactive, or ongoing digital support or behavioral prompts during the study period This group differs from the experimental arm by receiving only static educational material, without any interactive or adaptive behavioral support system. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cognitive function
Cognitive function will be assessed using the Mini-Mental State Examination (MMSE), a standardized tool evaluating orientation, memory, attention, language, and visuospatial abilities. Higher scores indicate better cognitive performance.
Measured: Day 0, 3. Month, 6. Month
Secondary outcomes (1)
Physical activity level
Physical activity level will be measured using the Physical Activity Scale for the Elderly (PASE), which assesses the frequency and duration of physical activity in older adults, including leisure, household, and occupational activities. Higher scores indicate higher physical activity levels.
Measured: Day 0, 3. Month, 6. Month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 May 2026
- Study start1 Aug 2026 (estimated)
- Primary completion30 Oct 2026 (estimated)
- Study completion30 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AgedStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 90 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Dokuz Eylul University
- Sponsor type
- University, hospital or other
- Collaborators
- Vinnova
- Responsible party
- Principal investigator, Makbule Neslişah Tan, Dokuz Eylul University
- Investigators
- Gizem Limnili, Study director, Dokuz Eylul University Faculty of Medicine Department of Family MedicineMakbule Neslişah Tan, Principal investigator, Dokuz Eylul University Faculty of Medicine Department of Family MedicineVildan Mevsim, Prof, Study chair, Dokuz Eylul University Faculty of Medicine Department of Family Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07596082
- Sponsor's protocol ID
- 2025/45-39
- Status last verified
- May 2026
- First submitted
- 25 Apr 2026
- Last updated
- 19 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Development of a Chatbot-supported Personalized Exercise Program for Older Adults and Evaluation of Its Effects on Cognitive Functions
- ClinicalTrials.gov ID
- NCT07596082
- Acronym / sponsor ID
- 2025/45-39
- Conditions
- Aged, Exercise, Cognition, Artificial Intelligence (AI), Health Behavior
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 90 participants (estimated)
- Lead sponsor
- Dokuz Eylul UniversityUniversity, hospital or other
- Collaborators
- Vinnova
- Study start
- 1 Aug 2026 (estimated)
- Primary completion
- 30 Oct 2026 (estimated)
- Study completion
- 30 Oct 2026 (estimated)
- First posted
- 19 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to develop an artificial intelligence-based chatbot application to support exercise behavior in individuals aged 60 and over who do not regularly exercise, and to evaluate its effectiveness. In addition, the study aims to examine the effects of changes in exercise habits on the cognitive (mental) functions of older adults.
In this study, the impact of a chatbot-supported personalized exercise program on cognitive functions in older individuals will be evaluated. A total of 90 participants is planned for inclusion in this study.
If you agree to participate in this study, depending on the group you are assigned to, you may receive:
- An artificial intelligence-based chatbot program, along with educational materials about the importance of exercise, or
- Only educational materials (brochures) prepared by the researchers about the importance of exercise.
At the beginning of the study, you will be asked to complete a data collection form. The same form will also be administered at week 12 and week 24.
This form will include:
- Basic information such as your age and gender,
- Questions about your exercise habits,
- A brief test to assess your cognitive (mental) functions,
- Questions evaluating your level of physical activity. The study duration is 24 weeks, including 12 weeks of intervention and 12 weeks of follow-up.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Artificial intelligence-supported chatbot and educational brochure on the importance of exercise | Experimental | Behavioral: Artificial intelligence-supported chatbotParticipants assigned to this arm will receive a combined digital and educational intervention designed to promote behavior change in physical activity. In addition to a standard researcher-developed informational brochure describing the health benefits of exercise, participants will have access to a chatbot supported by artificial intelligence technology. The chatbot will provide: * Interactive, on-demand communication regarding physical activity and exercise * Personalized educational messages tailored to participant needs and engagement patterns * Motivational support and behavioral prompts to encourage adherence to physical activity recommendations The brochure will provide standardized, non-interactive information on: * The importance and health benefits of regular exercise * General physical activity recommendations This intervention arm differs from comparator arms by incorporating an interactive, adaptive, and continuous AI-based support system. |
| Control (Brochure Only) Group | No intervention | –Participants assigned to this arm will receive a standard researcher-developed informational brochure on the importance of exercise, but will not receive any digital or interactive intervention. The brochure will provide standardized, non-interactive information on: * The importance and health benefits of regular exercise * General physical activity recommendations In addition to receiving the brochure, participants will: * Continue their usual daily activities and routine care * Do not have access to the artificial intelligence-supported chatbot * Not receive any personalized, interactive, or ongoing digital support or behavioral prompts during the study period This group differs from the experimental arm by receiving only static educational material, without any interactive or adaptive behavioral support system. |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
Key inclusion criteria (5 listed)
- Aged 65 years and older
- Normal or mildly impaired cognitive status
- Medical condition that does not prevent participation in physical activity
- Ability to use a smartphone or tablet (for chatbot access)
- Voluntary participation
Key exclusion criteria (5 listed)
- Moderate to severe dementia
- Severe depression or serious psychiatric disorders
- Acute cardiovascular risk
- Communication difficulties due to significant hearing or visual impairment
- Regular engagement in structured exercise within the past 6 months (participants in the maintenance phase of exercise behavior)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Artificial intelligence-supported chatbotParticipants will receive a combined behavioral intervention of an educational brochure developed by the Ministry of Health and access to an artificial intelligence (AI)-supported chatbot designed to promote physical activity. The brochure will provide standardized written information on the importance of exercise, including general recommendations, health benefits, and basic guidance for an active lifestyle. Participants will also have access to an AI-supported chatbot throughout the intervention period. The chatbot will deliver automated, interactive messages to increase physical activity, including motivational prompts, educational reinforcement, and behavior-change support. The intervention will be delivered digitally via the chatbot platform, with no medication or physical devices required. The total duration and frequency of chatbot interactions will be continuous and on-demand during the study period. | Behavioural | Artificial intelligence-supported chatbot and educational brochure on the importance of exercise |
Primary outcome
Cognitive function
Time frame: Day 0, 3. Month, 6. Month
Cognitive function will be assessed using the Mini-Mental State Examination (MMSE), a standardized tool evaluating orientation, memory, attention, language, and visuospatial abilities. Higher scores indicate better cognitive performance.
1 secondary outcome
Physical activity level
Time frame: Day 0, 3. Month, 6. Month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Gizem Limnili study director
Dokuz Eylul University Faculty of Medicine Department of Family Medicine
Makbule Neslişah Tan principal investigator
Dokuz Eylul University Faculty of Medicine Department of Family Medicine
Vildan Mevsim, Prof study chair
Dokuz Eylul University Faculty of Medicine Department of Family Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Artificial intelligence-supported chatbot in people with Aged and Exercise, run by Dokuz Eylul University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Gizem Limnili, MD (+902324124951, gizem.limnili@deu.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cognitive function (time frame: Day 0, 3. Month, 6. Month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.