SatietyNUBURNNCT07597382
A Study of NatureU Burn on Satiety in Healthy Adults
A study testing Glucose Reference Food and NatureU Burn Plus Glucose in people with Satiety and Appetite, run by OmniSolutions Laboratory Holdings Limited at 1 site in China.
Trial summary
This single-center, single-blind, non-randomized crossover exploratory study evaluated the short-term effects of NatureU Burn on postprandial satiety in healthy adults. NatureU Burn is an oral dietary supplement containing Irvingia gabonensis seed extract and high-molecular-weight inulin. Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Satiety, Appetite, Food Intake
- What is being tested?
- Glucose Reference Food and NatureU Burn Plus Glucose
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 14 participants
- Where
- 1 siteChina
- Study dates
- 22 Apr 2024to 5 May 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy adults aged 18 to 50 years.
- Male or female participants.
- Body mass index within the normal range of 18.5 to 23.9 kg/m2.
- Regular habit of eating breakfast.
- Able to fast for at least 10 hours after dinner.
- Signed informed consent before enrollment.
Who cannot join
- Pregnant or breastfeeding women.
- Individuals engaged in heavy physical labor or high-intensity exercise.
- Chronic sleep deprivation during the previous 3 months.
- Self-reported body weight increase or decrease of at least 4 kg during the previous 3 months.
- Current use of weight-loss medications.
- Special dietary patterns, such as low-carbohydrate diet or intermittent fasting.
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- Abnormal eating attitude based on eating attitude assessment.
- Serious cardiovascular, hepatic, renal, gastrointestinal, hematologic, or neurologic dysfunction.
- History of bariatric surgery.
- Major surgery or hospitalization within the previous 3 months.
- Eating disorders, including binge eating disorder, anorexia nervosa, or bulimia nervosa.
- Abnormal glucose metabolism or lipid metabolism.
- Intolerance or allergy to the test foods.
- Excessive smoking, defined as more than 15 cigarettes per day.
- Alcohol consumption greater than 15 g alcohol per day.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: A Single-Center, Single-Blind, Non-Randomized Crossover Exploratory Study of NatureU Burn With Glucose on Postprandial Satiety in Healthy Adults
This single-center, single-blind, non-randomized crossover exploratory study evaluated the short-term effects of NatureU Burn on postprandial satiety in healthy adults. NatureU Burn is an oral dietary supplement containing Irvingia gabonensis seed extract and high-molecular-weight inulin. Fourteen healthy adults were enrolled, and 12 participants completed the study and were included in the effectiveness analysis. Each participant completed two test sessions separated by at least 48 hours: a reference food session with 75 g medical anhydrous glucose in 250 mL warm purified water and a test food session with one capsule of NatureU Burn plus 75 g glucose in 250 mL warm purified water. Satiety-related questionnaire scores were assessed at fasting baseline and at 30, 60, 90, 120, 180, and 240 minutes after the first bite in each session. The study assessed fullness, hunger, desire for food, and prospective food consumption, and monitored adverse reactions.
Read the detailed description
This exploratory clinical study was conducted to assess whether NatureU Burn, when consumed with a glucose reference food, was associated with changes in satiety-related subjective indicators compared with glucose alone. Eligible healthy adults completed screening, signed informed consent, and underwent two independent test sessions. For 2 days before each test, participants were instructed to maintain regular routines and a normal diet. On the day before testing, participants ate dinner between 18:00 and 20:00, avoided high-fiber and high-sugar foods, and fasted after 20:00. On the test morning, participants avoided strenuous exercise, sat quietly for 10 minutes before testing, and completed a fasting satiety scale before taking the assigned food. Participants consumed the assigned food and water within 5 to 10 minutes, and completed the satiety scale at 30, 60, 90, 120, 180, and 240 minutes after the first bite. The four evaluated satiety indicators were fullness, hunger, desire for food, and prospective food consumption. Food-affected changes were calculated relative to fasting baseline and compared between the NatureU Burn plus glucose session and the glucose reference session. Safety monitoring included adverse reactions throughout the testing process.
- Conditions
- Satiety, Appetite, Food Intake, Fat Disorder, Obesity & Overweight
- Being tested
- Glucose Reference Food, NatureU Burn Plus Glucose
- Keywords
- NatureU Burn, Irvingia gabonensis seed extract, high-molecular-weight inulin, satiety, prospective food consumption, dietary supplement, NatureU
- Medical subject headings
- Lipid Metabolism Disorders, Obesity, Overweight
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Glucose Reference FoodOther
The reference food consisted of 75 g medical anhydrous glucose dissolved in 250 mL warm purified water.
NatureU Burn Plus GlucoseDietary supplement
Also called NatureU Burn, Irvingia gabonensis seed extract and inulin supplement
The test food consisted of one capsule of NatureU Burn plus 75 g medical anhydrous glucose dissolved in 250 mL warm purified water. NatureU Burn is an oral dietary supplement containing Irvingia gabonensis seed extract and high-molecular-weight inulin.
| Study group | Role | What they receive |
|---|---|---|
| Reference Food Session | Active comparator | Participants consumed 75 g medical anhydrous glucose dissolved in 250 mL warm purified water during the reference food session. Receives: Other: Glucose Reference Food |
| NatureU Burn Plus Glucose Session | Experimental | Participants consumed one capsule of NatureU Burn with 75 g medical anhydrous glucose dissolved in 250 mL warm purified water during the test food session. Receives: Dietary Supplement: NatureU Burn Plus Glucose |
What is being measured
The primary outcome is the main question the study is designed to answer.
Food-Affected Fullness Score After NatureU Burn Plus Glucose Compared With Glucose Alone
Fullness was assessed using the satiety scale. Food-affected fullness was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session. Fullness was assessed using the fullness item of the 100-point Satiety Rating Scale. The scale ranges from 0 to 100, with higher scores indicating greater fullness and a better satiety outcome. Food-affected fullness was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session. A larger positive change from baseline indicates a greater increase in fullness
Measured: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session.
Secondary outcomes (3)
Food-Affected Hunger Score After NatureU Burn Plus Glucose Compared With Glucose Alone
Hunger was assessed using the satiety scale. Food-affected hunger was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session.Hunger was assessed using the hunger item of the 100-point Satiety Rating Scale. The scale ranges from 0 to 100, with higher scores indicating greater hunger and a worse satiety outcome. Food-affected hunger was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session. A larger negative change from baseline indicates a greater reduction in hunger.
Measured: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session
Food-Affected Desire for Food Score After NatureU Burn Plus Glucose Compared With Glucose Alone
Desire for food was assessed using the satiety scale. Food-affected desire for food was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session.Desire for food was assessed using the desire-for-food item of the 100-point Satiety Rating Scale. The scale ranges from 0 to 100, with higher scores indicating greater desire for food and a worse satiety outcome. Food-affected desire for food was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session. A larger negative change from baseline indicates a greater reduction in desire for food
Measured: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session
Food-Affected Prospective Food Consumption Score After NatureU Burn Plus Glucose Compared With Glucose Alone
Prospective food consumption was assessed using the satiety scale. Food-affected prospective food consumption was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session.
Measured: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 May 2026
- Study start22 Apr 2024
- Primary completion26 Apr 2024
- Study completion5 May 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for SatietyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Model description
- Each participant completed two test sessions: one reference food session with glucose alone and one test food session with NatureU Burn plus glucose. The sessions were separated by at least 48 hours. The study used a non-randomized crossover design.
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 14 participants (actual)
Sponsor and investigators
- Lead sponsor
- OmniSolutions Laboratory Holdings Limited
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
- Investigators
- Luke Law, Dr, Study director, OmniSolutions Laboratory Holdings Limited
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07597382
- Sponsor's protocol ID
- NATUREU-BURN-2024-SAT
- Other IDs
- 2024041001
- Acronym
- NUBURN
- Status last verified
- May 2026
- First submitted
- 11 May 2026
- Last updated
- 19 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared due to privacy protection and ethical considerations.
Publications
Luo L, Law L, Yu M, Zhang N, Yang M. Participant Experiences from Chronic Administration of Irvingia Gabonensis Seed Extract and Inulin on the Body's Satiety: An Exploratory Analysis of a Single-Blind Clinical Trial. Current Topics in Nutraceutical Research. 2025;23(1):56-63. doi:10.37290/ctnr2641-452X.22:56-63.
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Single-Center, Single-Blind, Non-Randomized Crossover Exploratory Study of NatureU Burn With Glucose on Postprandial Satiety in Healthy Adults
- ClinicalTrials.gov ID
- NCT07597382
- Acronym / sponsor ID
- NUBURN / NATUREU-BURN-2024-SAT
- Conditions
- Satiety, Appetite, Food Intake, Fat Disorder, Obesity & Overweight
- Keywords
- NatureU Burn, Irvingia gabonensis seed extract, high-molecular-weight inulin, satiety, prospective food consumption, dietary supplement, NatureU
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 14 participants (actual)
- Lead sponsor
- OmniSolutions Laboratory Holdings LimitedIndustry (pharma, biotech, devices)
- Study start
- 22 Apr 2024 (actual)
- Primary completion
- 26 Apr 2024 (actual)
- Study completion
- 5 May 2024 (actual)
- First posted
- 19 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This single-center, single-blind, non-randomized crossover exploratory study evaluated the short-term effects of NatureU Burn on postprandial satiety in healthy adults. NatureU Burn is an oral dietary supplement containing Irvingia gabonensis seed extract and high-molecular-weight inulin. Fourteen healthy adults were enrolled, and 12 participants completed the study and were included in the effectiveness analysis. Each participant completed two test sessions separated by at least 48 hours: a reference food session with 75 g medical anhydrous glucose in 250 mL warm purified water and a test food session with one capsule of NatureU Burn plus 75 g glucose in 250 mL warm purified water. Satiety-related questionnaire scores were assessed at fasting baseline and at 30, 60, 90, 120, 180, and 240 minutes after the first bite in each session. The study assessed fullness, hunger, desire for food, and prospective food consumption, and monitored adverse reactions.
Detailed description
This exploratory clinical study was conducted to assess whether NatureU Burn, when consumed with a glucose reference food, was associated with changes in satiety-related subjective indicators compared with glucose alone. Eligible healthy adults completed screening, signed informed consent, and underwent two independent test sessions. For 2 days before each test, participants were instructed to maintain regular routines and a normal diet. On the day before testing, participants ate dinner between 18:00 and 20:00, avoided high-fiber and high-sugar foods, and fasted after 20:00. On the test morning, participants avoided strenuous exercise, sat quietly for 10 minutes before testing, and completed a fasting satiety scale before taking the assigned food. Participants consumed the assigned food and water within 5 to 10 minutes, and completed the satiety scale at 30, 60, 90, 120, 180, and 240 minutes after the first bite. The four evaluated satiety indicators were fullness, hunger, desire for food, and prospective food consumption. Food-affected changes were calculated relative to fasting baseline and compared between the NatureU Burn plus glucose session and the glucose reference session. Safety monitoring included adverse reactions throughout the testing process.
Study design
- Primary purpose
- Other
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Each participant completed two test sessions: one reference food session with glucose alone and one test food session with NatureU Burn plus glucose. The sessions were separated by at least 48 hours. The study used a non-randomized crossover design.
| Arm | Type | Receives |
|---|---|---|
| Reference Food Session | Active comparator | Other: Glucose Reference FoodParticipants consumed 75 g medical anhydrous glucose dissolved in 250 mL warm purified water during the reference food session. |
| NatureU Burn Plus Glucose Session | Experimental | Dietary Supplement: NatureU Burn Plus GlucoseParticipants consumed one capsule of NatureU Burn with 75 g medical anhydrous glucose dissolved in 250 mL warm purified water during the test food session. |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Healthy adults aged 18 to 50 years.
- Male or female participants.
- Body mass index within the normal range of 18.5 to 23.9 kg/m2.
- Regular habit of eating breakfast.
- Able to fast for at least 10 hours after dinner.
Key exclusion criteria (15 listed)
- Pregnant or breastfeeding women.
- Individuals engaged in heavy physical labor or high-intensity exercise.
- Chronic sleep deprivation during the previous 3 months.
- Self-reported body weight increase or decrease of at least 4 kg during the previous 3 months.
- Current use of weight-loss medications.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Glucose Reference FoodThe reference food consisted of 75 g medical anhydrous glucose dissolved in 250 mL warm purified water. | Other | Reference Food Session |
| NatureU Burn Plus GlucoseAlso: NatureU Burn, Irvingia gabonensis seed extract and inulin supplementThe test food consisted of one capsule of NatureU Burn plus 75 g medical anhydrous glucose dissolved in 250 mL warm purified water. NatureU Burn is an oral dietary supplement containing Irvingia gabonensis seed extract and high-molecular-weight inulin. | Dietary supplement | NatureU Burn Plus Glucose Session |
Primary outcome
Food-Affected Fullness Score After NatureU Burn Plus Glucose Compared With Glucose Alone
Time frame: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session.
Fullness was assessed using the satiety scale. Food-affected fullness was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session. Fullness was assessed using the fullness item of the 100-point Satiety Rating Scale. The scale ranges from 0 to 100, with higher scores indicating greater fullness and a better satiety outcome. Food-affected fullness was calculated as the change from fasting baseline at each postprandial time point and compared between the NatureU Burn plus glucose test session and the glucose reference session. A larger positive change from baseline indicates a greater increase in fullness
3 secondary outcomes
Food-Affected Hunger Score After NatureU Burn Plus Glucose Compared With Glucose Alone
Time frame: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session
Food-Affected Desire for Food Score After NatureU Burn Plus Glucose Compared With Glucose Alone
Time frame: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session
Food-Affected Prospective Food Consumption Score After NatureU Burn Plus Glucose Compared With Glucose Alone
Time frame: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- Results publicationLuo L, Law L, Yu M, Zhang N, Yang M. Participant Experiences from Chronic Administration of Irvingia Gabonensis Seed Extract and Inulin on the Body's Satiety: An Exploratory Analysis of a Single-Blind Clinical Trial. Current Topics in Nutraceutical Research. 2025;23(1):56-63. doi:10.37290/ctnr2641-452X.22:56-63.
- Published article in Current Topics in Nutraceutical ResearchLink provided by the sponsor.
- Individual participant dataSharing planned: No. Individual participant data will not be shared due to privacy protection and ethical considerations.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Luke Law, Dr study director
OmniSolutions Laboratory Holdings Limited
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Glucose Reference Food and NatureU Burn Plus Glucose in people with Satiety and Appetite, run by OmniSolutions Laboratory Holdings Limited at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 15 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Food-Affected Fullness Score After NatureU Burn Plus Glucose Compared With Glucose Alone (time frame: Fasting baseline before food intake and 30, 60, 90, 120, 180, and 240 minutes after the first bite in each test session.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07597382, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.