CancerCEICSNCT07600294
Integrated Cancer Services in Thailand: A Prototype for Excellence
A study testing Health Service Delivery Model in people with Cancer, run by Chulabhorn Cancer Center at 1 site in Thailand.
Trial summary
Cancer is a significant health crisis globally and specifically within Thailand, where it affects more than 122,000 individuals every year and leads to approximately 86,000 deaths. Beyond the physical and emotional toll on patients, the disease creates immense social and economic challenges. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Cancer
- What is being tested?
- Health Service Delivery Model
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 358 participants
- Where
- 1 siteThailand
- Study dates
- 2 Mar 2024to 13 Jul 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Group 1: Service Recipients
- This group included patients and their family members who received services at the prototype center. The criteria for inclusion were the following:
- Age: Must be 20 years or older. Capacity: Must be able to express their opinions regarding the comprehensive cancer services.
- Consent: Must be willing to participate in the research study. Group 2: Service Providers
- This group consisted of 30 healthcare professionals (such as physicians, nurses, and pharmacists) directly involved in delivering care. The criteria for inclusion were:
- ,Age and Sex: Must be at least 20 years old; there were no restrictions regarding sex.
Show all 13Show fewer
- Professional Status: Must be actively providing services at the Comprehensive Cancer Centre of Excellence or its affiliated network facilities.
- Knowledge Base: Must possess specific knowledge of the center's administrative and service systems.
- Consent: Must express a willingness to participate in the study. Group 3: Cancer Care Experts
- This group included 15 experts (administrators, academics, and researchers) who provided qualitative evaluation. The criteria for inclusion were:
- Professional Experience: Must have a minimum of five years of experience in the field of cancer care.
- Expertise: Must have the ability to provide deep insights into comprehensive cancer services.
- Consent: Must be willing to participate in the research. Note: There were no restrictions regarding the sex or age of these experts.
Who cannot join
- Group 1 (Service Recipients): Participants were required to be at least 20 years old, have the ability to express their opinions regarding the center's services, and be willing to participate in the study.
- Group 2 (Service Providers): Eligible healthcare professionals had to be at least 20 years old, be actively providing services at the prototype center or its affiliated facilities, and possess specific knowledge of the center's administrative and service systems.
- Group 3 (Cancer Care Experts): These individuals were required to have a minimum of five years of experience in cancer care and the capacity to provide deep insights into comprehensive cancer services. The sources note there were no restrictions regarding the sex or age of these experts
Trial locations and contacts
1 site in 1 country.
Thailand1 site
Princess Agrarajakumari Faculty of Nursing, Chulabhorn Royal Academy
Bangkok, 10210
About this study
Official title: Development and Implementation of a Prototype Centre of Excellence in Integrated Cancer Services in Thailand: A Feasibility Study
Cancer is a significant health crisis globally and specifically within Thailand, where it affects more than 122,000 individuals every year and leads to approximately 86,000 deaths. Beyond the physical and emotional toll on patients, the disease creates immense social and economic challenges.
In Thailand, cancer treatment costs exceed 26 billion baht (about $800 million USD) annually. Families often face out-of-pocket costs for cancer care that exceed 30% to 40% of their total household income. Furthermore, the aging of Thai society and lifestyle changes-such as "Westernized" diets and sedentary behavior-are expected to drive these numbers even higher. This situation has created an urgent need for new healthcare models that reduce the burden on major hospitals and make care more accessible to the public. The Project Goal: A new model of care to address these challenges: Researchers developed a prototype Center of Excellence in Integrated Cancer Services. The goal was to test whether a specialized cancer unit could be successfully integrated into a local community clinic rather than functioning as a large, separate hospital.
The study used Donabedian's model to evaluate quality, focusing on three specific areas: Structure: The physical setting, equipment, and staff. Process: How the services are actually delivered and Outcomes: The results of the care and the satisfaction of those involved. Phase of Development and Implementation The project was a three-year initiative funded by the National Science, Research, and Innovation Fund of Thailand. Phase 1: Focused on the conceptual design of the center. Phase 2: Involved detailed planning and the development of digital information systems. This is at Phase 3: Focused on the actual implementation and testing of the prototype center in Bangkok
Read the detailed description
Services Provided to the Community The center followed Thailand's national "7-branch" Cancer Service Plan, focusing specifically on the first two foundational branches for this pilot phase :Cancer Prevention and Risk Reduction: Counseling on healthy lifestyle modifications. Programs to reduce tobacco and alcohol use. Education regarding the HPV vaccine. General health literacy promotion to help people understand their risks. Cancer Screening and Early Detection: Clinical breast exams to check for abnormalities. Cervical cancer screening. Colorectal cancer screening. Risk assessments and established protocols to refer patients to major hospitals if abnormalities were found.
The other five branches-diagnosis, treatment, palliative care, informatics, and research-were supported through integrated referral pathways rather than being performed directly at the community unit.
Digital Innovation and Technology: A key feature of the center was the use of health information technology to bridge the gap between patients and providers. These tools included: Mobile Health Applications: Used for tracking symptoms and providing educational outreach. Electronic Health Records (EHRs): Facilitated real-time data sharing among the care team.
Virtual Consultations: Allowed for remote support and counseling. Artificial Intelligence (AI): The center planned for future integration of AI to assist in more accurate and efficient cancer screening
- Conditions
- Cancer
- Being tested
- Health Service Delivery Model
- Keywords
- Feasibility Study, Comprehensive Cancer Centre of Excellence
- Medical subject headings
- Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Health Service Delivery ModelOther
Also called Lak Si is Alert to Fight Cancer
The intervention in this study is the development and implementation of a prototype Centre of Excellence (COE) in Integrated Cancer Services in Bangkok, Thailand. This model is fundamentally distinguished by its integration into a local community setting-specifically established within the Warm Community Nurse Clinic-rather than functioning as a standalone, large-scale hospital. By leveraging the community's existing familiarity with the clinic, the intervention aims to improve accessibility and trust while reducing the financial and logistical burdens typically associated with seeking cancer care at major medical centers.
| Study group | Role | What they receive |
|---|---|---|
| Prototype Centre of Excellence in Integrated Cancer Services | Experimental | The intervention, as a pilot unit, was established within the Warm Community Nurse Clinic to deliver community-based cancer prevention and screening services
. It highlights the model's core purpose as an integrated healthcare hub designed to test the feasibility of scaling such centres nationwide in Thailand Receives: Other: Health Service Delivery Model |
What is being measured
The primary outcome is the main question the study is designed to answer.
Satisfaction Levels with Service Delivery
Satisfaction is measured across three domains: Structure (the physical setting and resources), Process (the delivery of care and communication), and Outcomes (the results and perceived benefits)
Measured: Data was collected over the 12-month implementation period of Phase 3, from October 2023 to September 2024
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 May 2026
- Study start2 Mar 2024
- Primary completion13 Jul 2024
- Study completion13 Jul 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (8)Papers the sponsor has linked to this study.
- Other trials for CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- A research and development (R\&D) project employing an experimental research design.
- Masking
- None (open label)
- Enrolment
- 358 participants (actual)
Sponsor and investigators
- Lead sponsor
- Chulabhorn Cancer Center
- Sponsor type
- University, hospital or other
- Collaborators
- Chulabhorn Royal Academy
- Responsible party
- Principal investigator, Saengrawee Thanthong, Chulabhorn Cancer Center
- Investigators
- Vilaivan Thongcharoen, PhD, Principal investigator, PAFN, CRA
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07600294
- Sponsor's protocol ID
- 50182
- Other IDs
- 180873
- Acronym
- CEICS
- Status last verified
- May 2026
- First submitted
- 14 May 2026
- Last updated
- 20 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: According to the sources, the research was conducted with strict protocols to maintain participant confidentiality and anonymity, including the use of anonymous codes and secure data storage. Crucially, the study's ethical guidelines mandated that all data were to be destroyed one year after the completion of the study. While the manuscript specifies that all data supporting the findings are included within the article and its supplementary materials, the raw individual participant data (IPD) is not available for sharing to ensure the protection of participant privacy and to remain in compliance with the data management plan approved by the Human Research Ethics Committee of Chulabhorn Royal Academy.
Publications
World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013 Nov 27;310(20):2191-4. doi: 10.1001/jama.2013.281053. No abstract available.
PubMed 24141714Elrod JK, Fortenberry JL Jr. Centers of excellence in healthcare institutions: what they are and how to assemble them. BMC Health Serv Res. 2017 Jul 11;17(Suppl 1):425. doi: 10.1186/s12913-017-2340-y.
PubMed 28722562Insamran W, Sangrajrang S. National Cancer Control Program of Thailand. Asian Pac J Cancer Prev. 2020 Mar 1;21(3):577-582. doi: 10.31557/APJCP.2020.21.3.577.
PubMed 32212781Sedgewick JR, Ali A, Badea A, Carr T, Groot G. Service providers' perceptions of support needs for Indigenous cancer patients in Saskatchewan: a needs assessment. BMC Health Serv Res. 2021 Aug 21;21(1):848. doi: 10.1186/s12913-021-06821-6.
PubMed 34419035Adams RN, Mosher CE, Cannady RS, Lucette A, Kim Y. Caregiving experiences predict changes in spiritual well-being among family caregivers of cancer patients. Psychooncology. 2014 Oct;23(10):1178-84. doi: 10.1002/pon.3558. Epub 2014 May 17.
PubMed 24839205ACTION Study Group. Policy and priorities for national cancer control planning in low- and middle-income countries: Lessons from the Association of Southeast Asian Nations (ASEAN) Costs in Oncology prospective cohort study. Eur J Cancer. 2017 Mar;74:26-37. doi: 10.1016/j.ejca.2016.12.014. Epub 2017 Feb 6.
PubMed 28335885Iragorri N, de Oliveira C, Fitzgerald N, Essue B. The Out-of-Pocket Cost Burden of Cancer Care-A Systematic Literature Review. Curr Oncol. 2021 Mar 15;28(2):1216-1248. doi: 10.3390/curroncol28020117.
PubMed 33804288Reungwetwattana T, Oranratnachai S, Puataweepong P, Tangsujaritvijit V, Cherntanomwong P. Lung Cancer in Thailand. J Thorac Oncol. 2020 Nov;15(11):1714-1721. doi: 10.1016/j.jtho.2020.04.024. Epub 2020 Oct 23. No abstract available.
PubMed 33148410
Study at a glance
From the registry record, last updated by the sponsor on 20 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Development and Implementation of a Prototype Centre of Excellence in Integrated Cancer Services in Thailand: A Feasibility Study
- ClinicalTrials.gov ID
- NCT07600294
- Acronym / sponsor ID
- CEICS / 50182
- Conditions
- Cancer
- Keywords
- Feasibility Study, Comprehensive Cancer Centre of Excellence
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 358 participants (actual)
- Lead sponsor
- Chulabhorn Cancer CenterUniversity, hospital or other
- Collaborators
- Chulabhorn Royal Academy
- Study start
- 2 Mar 2024 (actual)
- Primary completion
- 13 Jul 2024 (actual)
- Study completion
- 13 Jul 2024 (actual)
- First posted
- 20 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cancer is a significant health crisis globally and specifically within Thailand, where it affects more than 122,000 individuals every year and leads to approximately 86,000 deaths. Beyond the physical and emotional toll on patients, the disease creates immense social and economic challenges.
In Thailand, cancer treatment costs exceed 26 billion baht (about $800 million USD) annually. Families often face out-of-pocket costs for cancer care that exceed 30% to 40% of their total household income. Furthermore, the aging of Thai society and lifestyle changes-such as "Westernized" diets and sedentary behavior-are expected to drive these numbers even higher. This situation has created an urgent need for new healthcare models that reduce the burden on major hospitals and make care more accessible to the public. The Project Goal: A new model of care to address these challenges: Researchers developed a prototype Center of Excellence in Integrated Cancer Services. The goal was to test whether a specialized cancer unit could be successfully integrated into a local community clinic rather than functioning as a large, separate hospital.
The study used Donabedian's model to evaluate quality, focusing on three specific areas: Structure: The physical setting, equipment, and staff. Process: How the services are actually delivered and Outcomes: The results of the care and the satisfaction of those involved. Phase of Development and Implementation The project was a three-year initiative funded by the National Science, Research, and Innovation Fund of Thailand. Phase 1: Focused on the conceptual design of the center. Phase 2: Involved detailed planning and the development of digital information systems. This is at Phase 3: Focused on the actual implementation and testing of the prototype center in Bangkok
Detailed description
Services Provided to the Community The center followed Thailand's national "7-branch" Cancer Service Plan, focusing specifically on the first two foundational branches for this pilot phase :Cancer Prevention and Risk Reduction: Counseling on healthy lifestyle modifications. Programs to reduce tobacco and alcohol use. Education regarding the HPV vaccine. General health literacy promotion to help people understand their risks. Cancer Screening and Early Detection: Clinical breast exams to check for abnormalities. Cervical cancer screening. Colorectal cancer screening. Risk assessments and established protocols to refer patients to major hospitals if abnormalities were found.
The other five branches-diagnosis, treatment, palliative care, informatics, and research-were supported through integrated referral pathways rather than being performed directly at the community unit.
Digital Innovation and Technology: A key feature of the center was the use of health information technology to bridge the gap between patients and providers. These tools included: Mobile Health Applications: Used for tracking symptoms and providing educational outreach. Electronic Health Records (EHRs): Facilitated real-time data sharing among the care team.
Virtual Consultations: Allowed for remote support and counseling. Artificial Intelligence (AI): The center planned for future integration of AI to assist in more accurate and efficient cancer screening
Study design
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- A research and development (R\&D) project employing an experimental research design.
| Arm | Type | Receives |
|---|---|---|
| Prototype Centre of Excellence in Integrated Cancer Services | Experimental | Other: Health Service Delivery ModelThe intervention, as a pilot unit, was established within the Warm Community Nurse Clinic to deliver community-based cancer prevention and screening services . It highlights the model's core purpose as an integrated healthcare hub designed to test the feasibility of scaling such centres nationwide in Thailand |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (13 listed)
- Group 1: Service Recipients
- This group included patients and their family members who received services at the prototype center. The criteria for inclusion were the following:
- Age: Must be 20 years or older. Capacity: Must be able to express their opinions regarding the comprehensive cancer services.
- Consent: Must be willing to participate in the research study. Group 2: Service Providers
- This group consisted of 30 healthcare professionals (such as physicians, nurses, and pharmacists) directly involved in delivering care. The criteria for inclusion were:
Key exclusion criteria (3 listed)
- Group 1 (Service Recipients): Participants were required to be at least 20 years old, have the ability to express their opinions regarding the center's services, and be willing to participate in the study.
- Group 2 (Service Providers): Eligible healthcare professionals had to be at least 20 years old, be actively providing services at the prototype center or its affiliated facilities, and possess specific knowledge of the center's administrative and service systems.
- Group 3 (Cancer Care Experts): These individuals were required to have a minimum of five years of experience in cancer care and the capacity to provide deep insights into comprehensive cancer services. The sources note there were no restrictions regarding the sex or age of these experts
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Health Service Delivery ModelAlso: Lak Si is Alert to Fight CancerThe intervention in this study is the development and implementation of a prototype Centre of Excellence (COE) in Integrated Cancer Services in Bangkok, Thailand. This model is fundamentally distinguished by its integration into a local community setting-specifically established within the Warm Community Nurse Clinic-rather than functioning as a standalone, large-scale hospital. By leveraging the community's existing familiarity with the clinic, the intervention aims to improve accessibility and trust while reducing the financial and logistical burdens typically associated with seeking cancer care at major medical centers. | Other | Prototype Centre of Excellence in Integrated Cancer Services |
Primary outcome
Satisfaction Levels with Service Delivery
Time frame: Data was collected over the 12-month implementation period of Phase 3, from October 2023 to September 2024
Satisfaction is measured across three domains: Structure (the physical setting and resources), Process (the delivery of care and communication), and Outcomes (the results and perceived benefits)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 May 2026.
- Background: PubMed 24141714World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013 Nov 27;310(20):2191-4. doi: 10.1001/jama.2013.281053. No abstract available.
- Background: PubMed 28722562Elrod JK, Fortenberry JL Jr. Centers of excellence in healthcare institutions: what they are and how to assemble them. BMC Health Serv Res. 2017 Jul 11;17(Suppl 1):425. doi: 10.1186/s12913-017-2340-y.
- Background: PubMed 32212781Insamran W, Sangrajrang S. National Cancer Control Program of Thailand. Asian Pac J Cancer Prev. 2020 Mar 1;21(3):577-582. doi: 10.31557/APJCP.2020.21.3.577.
- Background: PubMed 34419035Sedgewick JR, Ali A, Badea A, Carr T, Groot G. Service providers' perceptions of support needs for Indigenous cancer patients in Saskatchewan: a needs assessment. BMC Health Serv Res. 2021 Aug 21;21(1):848. doi: 10.1186/s12913-021-06821-6.
- Background: PubMed 24839205Adams RN, Mosher CE, Cannady RS, Lucette A, Kim Y. Caregiving experiences predict changes in spiritual well-being among family caregivers of cancer patients. Psychooncology. 2014 Oct;23(10):1178-84. doi: 10.1002/pon.3558. Epub 2014 May 17.
- Background: PubMed 28335885ACTION Study Group. Policy and priorities for national cancer control planning in low- and middle-income countries: Lessons from the Association of Southeast Asian Nations (ASEAN) Costs in Oncology prospective cohort study. Eur J Cancer. 2017 Mar;74:26-37. doi: 10.1016/j.ejca.2016.12.014. Epub 2017 Feb 6.
- Background: PubMed 33804288Iragorri N, de Oliveira C, Fitzgerald N, Essue B. The Out-of-Pocket Cost Burden of Cancer Care-A Systematic Literature Review. Curr Oncol. 2021 Mar 15;28(2):1216-1248. doi: 10.3390/curroncol28020117.
- Background: PubMed 33148410Reungwetwattana T, Oranratnachai S, Puataweepong P, Tangsujaritvijit V, Cherntanomwong P. Lung Cancer in Thailand. J Thorac Oncol. 2020 Nov;15(11):1714-1721. doi: 10.1016/j.jtho.2020.04.024. Epub 2020 Oct 23. No abstract available.
- WHO databaseLink provided by the sponsor.
- The Global observatory databaseLink provided by the sponsor.
- The Importance of Communication in Addressing Cancer as a Public Health Crisis: Office of the National Health Commission; 2020Link provided by the sponsor.
- Individual participant dataSharing planned: No. According to the sources, the research was conducted with strict protocols to maintain participant confidentiality and anonymity, including the use of anonymous codes and secure data storage. Crucially, the study's ethical guidelines mandated that all data were to be destroyed one year after the completion of the study. While the manuscript specifies that all data supporting the findings are included within the article and its supplementary materials, the raw individual participant data (IPD) is not available for sharing to ensure the protection of participant privacy and to remain in compliance with the data management plan approved by the Human Research Ethics Committee of Chulabhorn Royal Academy.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Vilaivan Thongcharoen, PhD principal investigator
PAFN, CRA
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Health Service Delivery Model in people with Cancer, run by Chulabhorn Cancer Center at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 13 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Satisfaction Levels with Service Delivery (time frame: Data was collected over the 12-month implementation period of Phase 3, from October 2023 to September 2024). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07600294, which also lists 8 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 May 2026.