Mental HealthNCT07601477
Assessing the Impact of the Personalized Medicine Clinic on Mental Health Outcomes
An observational study of Mental Health and Depressive Disorder, run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's.
Trial summary
The aim of this study is to investigate if personalized dosing of antidepressant medications using information gathered at the Personalized Medicine Clinic can improve patients' mental health. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Mental Health, Depressive Disorder, Pharmacogenetic Testing
- What is being tested?
- Personalized Medicine Clinic
- How many people
- 200 participants
- Where
- No sites listed yet
- Study dates
- Jul 2026to Jun 2028
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients referred to the Personalized Medicine clinic for genotype-guided drug dosing and selection related to mental health pharmacotherapy as part of clinical care.
Who may be able to join
- Depressive symptoms
Who cannot join
- Patients who do not speak English
- Patients with severe mental illness including hospitalized patients or patients with suicidal ideation
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
The aim of this study is to investigate if personalized dosing of antidepressant medications using information gathered at the Personalized Medicine Clinic can improve patients' mental health. The main question it aims to answer is if the Personalized Medicine Clinic can improve depressive symptoms based on the CES-D survey score.
- Being tested
- Personalized Medicine Clinic
- Medical subject headings
- Psychological Well-Being, Depressive Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Personalized Medicine ClinicOther
Personalized Medicine Clinic services with specific focus on pharmacogenetic recommendations and patient education.
| Study group | Role | What they receive |
|---|---|---|
| Personalized Medicine Cohort | Patients referred to the Personalized Medicine Clinic for guidance on antidepressant therapy. Receives: Other: Personalized Medicine Clinic |
What is being measured
The primary outcome is the main question the study is designed to answer.
CES-D Survey Score
CES-D survey score is a 20-item self-reported questionnaire that was designed to assess depressive symptoms. The score is from 0-60 with higher numbers indicating greater depressive symptoms.
Measured: From enrollment to 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study startJul 2026 (estimated)
- Primary completionJun 2028 (estimated)
- Study completionJun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Mental HealthStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Richard Kim, London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07601477
- Sponsor's protocol ID
- 128940
- Status last verified
- May 2026
- First submitted
- 15 May 2026
- Last updated
- 26 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No