Subacromial Impingement SyndromeNCT07601568
Pectoralis Minor Release in Patients With Subacromial Impingement Syndrome
A study testing conventional physical therapy and Experimental group therapy in people with Subacromial Impingement Syndrome, run by Cairo University at 1 site in Egypt.
Trial summary
To investigate the effect of PMI release on subacromial space, pectoralis minor length, shoulders ROM, shoulder joint pain, and functional ability in patients with SAIS. Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Subacromial Impingement Syndrome
- What is being tested?
- conventional physical therapy and Experimental group therapy
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 11 May 2026to 12 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients with chronic unilateral SAIS.
- Patient age average 40- 60 years old from both sexes (Michael and Gail 2000).
- Decreased AHD less than 10mm by x-ray image (Mean AHD in absence of rotator cuff tear is 10.5mm (Goutallier et al., 2011)).
- Decreased of active shoulder ROM.
- Presence of unilateral shoulder joint pain.
- Reliable patients.
Who cannot join
- All patients who have any of the following will be excluded from the study (Lewis and Valentine 2007)
- Intra articular injection.
- Arthroscopic intervention.
- Previous shoulder fracture.
- Shoulder subluxation.
- Adhesive capsulitis.
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- Shoulder osteoarthritis.
- Any previous operation on cervical and shoulder region.
- Mastectomy on the same side of shoulder impingement.
- Patients with neurological disorder that may contribute performance the procedure instructions.
- Osteoporosis.
- Pregnant and lactating woman.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Efficacy of Pectoralis Minor Release on Subacromial Space in Patients With Subacromial Impingement Syndrome
To investigate the effect of PMI release on subacromial space, pectoralis minor length, shoulders ROM, shoulder joint pain, and functional ability in patients with SAIS.
Read the detailed description
Statement of the problem:
This study will be designed to answer the following question Does PMI release have an effect on subacromial space in patients with SAIS?
The purposes of the study:
- To investigate the effect of PMI release on subacromial space in patients with SAIS.
- To investigate the effect of PMI release on pectoralis minor length in patients with SAIS.
- To investigate the effect of PMI release on shoulders ROM (flexion, abduction, internal and external rotation) in patients with SAIS.
- To investigate the effect of PMI release on shoulder joint pain in patients with SAIS.
- To investigate the effect of PMI release on functional ability in patients with SAIS.
- Conditions
- Subacromial Impingement Syndrome
- Being tested
- conventional physical therapy, Experimental group therapy
- Keywords
- Shoulder Joint, Subacromial Space, Pectoralis Minor
- Medical subject headings
- Shoulder Impingement Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
conventional physical therapyOther
Physiotherapy treatment included passive manual joint mobilization, home-based strengthening exercises and advice on posture, twice a week.
So, we will apply this conventional physical therapy to control group
- Postural correction exercise
- Patient can apply this exercise on prone lie position for against a wall as in figure 10.
- patient will start with chin in exercise, will asked to pull his chine in and push the wall, then hold for 15 seconds and repeat for 3 times.
- Patient will try to touch both shoulders to the wall and hold for 15 seconds.
- Patient will be asked to straight all spine against the wall and hold for 15 seconds.
- Scapular stabilization exercise Patient will lie prone with elbow extended, start to move his arm away from his body (horizontal abduction), with wait or without according to Lafayette muscle test results. Apply 2 cycle and each cycle will have 10 times repetitions
Experimental group therapyOther
Treatment will be conventional treatment with pectoralis minor release and stretch.
- Pectoralis minor stretch The subject lying in a supine position with a towel roll running the length of the thoracic spine. The subject's shoulder at 90° of abduction and external rotation and the elbow at 90° flexion while therapist applying a posterior force to the coracoid process, in this study stretch will be performed for two sequential repetitions, holding the stretches for 30 seconds with 30 second break
- Pectoralis minor release the subject in a supine position with the test arm at his side while the therapist palpated medially into the proximal axilla, followed by proceeding superiorly towards the coracoid process then applied pressure in the anterior direction, similar to attempting to lift the muscle, therapist applying tensile force directly to the pectoralis minor. The opposite therapist hand will stabilize the scapula and humeral head maintain for 30 seconds and repeat 2 times
| Study group | Role | What they receive |
|---|---|---|
| traditional group | Sham comparator | Thirty patients will receive traditional physical therapy treatment (Postural correction exercises and scapular stabilization exercises) at the painful shoulder, Treatment sessions will be two times per week for six weeks Receives: Other: conventional physical therapy |
| Experimental Group | Experimental | Thirty patients will receive traditional treatment plus pectoralis minor stretching and release, Treatment sessions will be two times per week for six weeks. Receives: Other: conventional physical therapy; Other: Experimental group therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Subacromial space will be measured by X-ray image
The radiograph will be done to measure acromio-humeral distance, which is considered the shortest distance between the inferior cortex of acromion and the top of humeral head. In normal shoulders, the sub acromial space was between 9 and 10 mm. The space was significantly greater in men, with a slight reduction with age. In middle age, a sub-acromial space less than 6 mm is pathological
Measured: 6 months
Secondary outcomes (4)
Pectoralis minor length will be measured by tape measurement
Participants will be asked to remain in a relaxed posture with the arms at the side in a neutral position, avoid postural correction, and exhale just before the measurement.
A tape measure was used to measure the linear distance between the origin and insertion of the muscle. The primary investigator of the study performed all measurements. The origin was defined as the inferior aspect of the 4th rib, which was one finger width lateral to the sternum, just lateral to the sternocostal junction. The insertion was defined as the medial-inferior aspect of the coracoid process .
Measured: 6 month
Shoulder joint ROM (flexion, abduction, internal and external rotation) will be measured by inclinometer
Shoulder flexion, abduction, internal and external rotation movements will be measured with the individual seated upright on a non-reclining high-back chair, to limit trunk compensation. The chair was the same for all movements performed by one individual, but different for each individual, to provide support up to the middle of the scapula.
Shoulder movements will be actively and passively evaluated for flexion in supine and seated positions, abduction, external rotation in a neutral position with 0° abduction (ERN), external rotation with the arm at 90° of abduction (ER90), and internal rotation with the arm at 90° of abduction (IR90) using an Acumar digital inclinometer .
Measured: 6 month
Pain intensity will be measured by using VAS ( visual analog scale)
The patients' pain severity will be evaluated using a visual analog scale (VAS). The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between 0 "no pain" and 10 "worst pain
Measured: 6 month
Identification of Functional Ability of the shoulder joint using Q-DASH questionnaire with Arabic version
The disabilities of the arm, shoulder and hand (DASH) questionnaire is a self-administered region-specific outcome instrument developed as a measure of self-rated upper extremity disability and symptoms The use of the DASH questionnaire as an outcomes instrument in patients with upper-extremity complaints. The main part of the Quick-DASH is a 14-item disability/symptom scale concerning the patient's health status during the preceding week. The items ask about the degree of difficulty in performing different physical activities as well as the problem's impact on social activities, work, sleep, and self-image. Each item has five response options. The scores for all items are then used to calculate a scale score ranging from 1 (no difficulty) to 5 ( unable).
Measured: 6 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study start11 May 2026
- Primary completion1 Jan 2027 (estimated)
- Study completion12 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Subacromial Impingement SyndromeStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Walaa Mostafa Abd El-Haleem, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07601568
- Sponsor's protocol ID
- P.T.REC/012/005809
- Status last verified
- May 2026
- First submitted
- 10 May 2026
- Last updated
- 22 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Abu EL Kasem Sh., Alaa F., Abd EL-Raoof N. et al., (2024):" Efficacy of Mulligan thoracic sustained natural apophyseal glides on sub-acromial pain in patients with sub-acromial impingement syndrome: a single-blinded randomized controlled trial "journal of manual & manipulative therapy 10.1080/10669817.2024.2341453 Amado A., Marques A., Maiorino R. et al., (2006):" An Anatomical Study of The Subcoracoid Space" CLINICS 2006;61(5):467-72 Ann Sisto S. and Dyson-Hudson T. (2007):" Dynamometry testing in spinal cord injury" Journal of Rehabilitation Research & Development, Volume 44, Number 1 Anne T., Herrington L., Horlsey I. et al. (2015):" An evidence-based review of current perceptions with regard to the subacromial space in shoulder impingement syndromes: Is it important and what influences it?" Clinical Biomechanics , Volume 30, Issue 7, August 2015, Pages 641-648
Study at a glance
From the registry record, last updated by the sponsor on 22 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficacy of Pectoralis Minor Release on Subacromial Space in Patients With Subacromial Impingement Syndrome
- ClinicalTrials.gov ID
- NCT07601568
- Acronym / sponsor ID
- P.T.REC/012/005809
- Conditions
- Subacromial Impingement Syndrome
- Keywords
- Shoulder Joint, Subacromial Space, Pectoralis Minor
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 11 May 2026 (actual)
- Primary completion
- 1 Jan 2027 (estimated)
- Study completion
- 12 Jan 2027 (estimated)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To investigate the effect of PMI release on subacromial space, pectoralis minor length, shoulders ROM, shoulder joint pain, and functional ability in patients with SAIS.
Detailed description
Statement of the problem:
This study will be designed to answer the following question Does PMI release have an effect on subacromial space in patients with SAIS?
The purposes of the study:
- To investigate the effect of PMI release on subacromial space in patients with SAIS.
- To investigate the effect of PMI release on pectoralis minor length in patients with SAIS.
- To investigate the effect of PMI release on shoulders ROM (flexion, abduction, internal and external rotation) in patients with SAIS.
- To investigate the effect of PMI release on shoulder joint pain in patients with SAIS.
- To investigate the effect of PMI release on functional ability in patients with SAIS.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| traditional group | Sham comparator | Other: conventional physical therapyThirty patients will receive traditional physical therapy treatment (Postural correction exercises and scapular stabilization exercises) at the painful shoulder, Treatment sessions will be two times per week for six weeks |
| Experimental Group | Experimental | Other: conventional physical therapy, Other: Experimental group therapyThirty patients will receive traditional treatment plus pectoralis minor stretching and release, Treatment sessions will be two times per week for six weeks. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Patients with chronic unilateral SAIS.
- Patient age average 40- 60 years old from both sexes (Michael and Gail 2000).
- Decreased AHD less than 10mm by x-ray image (Mean AHD in absence of rotator cuff tear is 10.5mm (Goutallier et al., 2011)).
- Decreased of active shoulder ROM.
- Presence of unilateral shoulder joint pain.
Key exclusion criteria (12 listed)
- All patients who have any of the following will be excluded from the study (Lewis and Valentine 2007)
- Intra articular injection.
- Arthroscopic intervention.
- Previous shoulder fracture.
- Shoulder subluxation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| conventional physical therapyPhysiotherapy treatment included passive manual joint mobilization, home-based strengthening exercises and advice on posture, twice a week. So, we will apply this conventional physical therapy to control group 1. Postural correction exercise * Patient can apply this exercise on prone lie position for against a wall as in figure 10. * patient will start with chin in exercise, will asked to pull his chine in and push the wall, then hold for 15 seconds and repeat for 3 times. * Patient will try to touch both shoulders to the wall and hold for 15 seconds. * Patient will be asked to straight all spine against the wall and hold for 15 seconds. 2. Scapular stabilization exercise Patient will lie prone with elbow extended, start to move his arm away from his body (horizontal abduction), with wait or without according to Lafayette muscle test results. Apply 2 cycle and each cycle will have 10 times repetitions | Other | Experimental Group, traditional group |
| Experimental group therapyTreatment will be conventional treatment with pectoralis minor release and stretch. * Pectoralis minor stretch The subject lying in a supine position with a towel roll running the length of the thoracic spine. The subject's shoulder at 90° of abduction and external rotation and the elbow at 90° flexion while therapist applying a posterior force to the coracoid process, in this study stretch will be performed for two sequential repetitions, holding the stretches for 30 seconds with 30 second break * Pectoralis minor release the subject in a supine position with the test arm at his side while the therapist palpated medially into the proximal axilla, followed by proceeding superiorly towards the coracoid process then applied pressure in the anterior direction, similar to attempting to lift the muscle, therapist applying tensile force directly to the pectoralis minor. The opposite therapist hand will stabilize the scapula and humeral head maintain for 30 seconds and repeat 2 times | Other | Experimental Group |
Primary outcome
Subacromial space will be measured by X-ray image
Time frame: 6 months
The radiograph will be done to measure acromio-humeral distance, which is considered the shortest distance between the inferior cortex of acromion and the top of humeral head. In normal shoulders, the sub acromial space was between 9 and 10 mm. The space was significantly greater in men, with a slight reduction with age. In middle age, a sub-acromial space less than 6 mm is pathological
4 secondary outcomes
Pectoralis minor length will be measured by tape measurement
Time frame: 6 month
Shoulder joint ROM (flexion, abduction, internal and external rotation) will be measured by inclinometer
Time frame: 6 month
Pain intensity will be measured by using VAS ( visual analog scale)
Time frame: 6 month
Identification of Functional Ability of the shoulder joint using Q-DASH questionnaire with Arabic version
Time frame: 6 month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 May 2026.
- BackgroundAbu EL Kasem Sh., Alaa F., Abd EL-Raoof N. et al., (2024):" Efficacy of Mulligan thoracic sustained natural apophyseal glides on sub-acromial pain in patients with sub-acromial impingement syndrome: a single-blinded randomized controlled trial "journal of manual & manipulative therapy 10.1080/10669817.2024.2341453 Amado A., Marques A., Maiorino R. et al., (2006):" An Anatomical Study of The Subcoracoid Space" CLINICS 2006;61(5):467-72 Ann Sisto S. and Dyson-Hudson T. (2007):" Dynamometry testing in spinal cord injury" Journal of Rehabilitation Research & Development, Volume 44, Number 1 Anne T., Herrington L., Horlsey I. et al. (2015):" An evidence-based review of current perceptions with regard to the subacromial space in shoulder impingement syndromes: Is it important and what influences it?" Clinical Biomechanics , Volume 30, Issue 7, August 2015, Pages 641-648
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing conventional physical therapy and Experimental group therapy in people with Subacromial Impingement Syndrome, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 22 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Subacromial space will be measured by X-ray image (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07601568, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 May 2026.