External Oblique Intercostal Fascial Plane BlockPhase 3NCT07601945
External Oblique Intercostal Fascial Plane Block Versus Rectus Sheath Block for Postoperative Analgesia
A Phase 3 study testing External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia in people with External Oblique Intercostal Fascial Plane Block and Rectus Sheath Block, run by Helwan University at 1 site in Egypt.
Trial summary
This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block, Pain
- What is being tested?
- External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 1 May 2023to 30 Jun 2025
- Phase
- Phase 3
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patients aged 18-65 years, classified as American Society of Anesthesiologists (ASA) physical status I or II [16], and scheduled for elective paraumbilical hernioplasty.
Who cannot join
- Patients with a history of prolonged opioid medication, allergy to local anesthetics, pregnancy, infection at the injection site, and/or coagulopathy.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: External Oblique Intercostal Fascial Plane Block Versus Rectus Sheath Block for Postoperative Analgesia After Paraumbilical Hernia Repair Surgery
This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty.
Read the detailed description
Background: Paraumbilical hernia repair is a frequently performed surgical procedure, often associated with significant postoperative pain and delayed recovery, which are major concerns for patients.
Objectives: This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty.
Methods: This prospective, randomized, single-blinded study enrolled 60 patients, divided into two groups (EOIPB and RSB), each comprising 30 participants. Blocks were administered after general anesthesia and prior to surgery. Patient demographics (age, weight), surgical duration, pain scores (measured by Numeric Rating Scale - NRS), total postoperative morphine consumption, intraoperative fentanyl consumption, and hemodynamic parameters (mean arterial pressure - MAP and heart rate - HR) were assessed.
- Being tested
- External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia
- Keywords
- External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block, Pain
- Medical subject headings
- Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
External Oblique Intercostal Fascial Plane Block for Postoperative AnalgesiaProcedure or surgery
After the induction of general anesthesia and approximately 15 minutes before the surgical incision, patients were randomly assigned to receive either the EOIPB (Group A) or the RSB (Group B).
| Study group | Role | What they receive |
|---|---|---|
| external oblique intercostal fascial plane block | Experimental | external oblique intercostal fascial plane block Receives: Procedure: External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia |
| rectus sheath block | Active comparator | rectus sheath block Receives: Procedure: External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia |
What is being measured
The primary outcome is the main question the study is designed to answer.
Total postoperative morphine consumption in milligrams during the first 24 hours after surgery
Total cumulative morphine requirement administered for postoperative analgesia during the first 24 hours following paraumbilical hernia repair surgery, measured in milligrams (mg).
Measured: First 24 hours postoperatively
Number of participants experiencing block-related or postoperative complications within 3 months after surgery
Assessment of postoperative and block-related complications including local anesthetic toxicity, hematoma, infection, nausea/vomiting, respiratory depression, and other adverse events recorded during the follow-up period.
Measured: 3 months after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study start1 May 2023
- Primary completion30 Apr 2025
- Study completion30 Jun 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for External Oblique Intercostal Fascial Plane BlockStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase 3
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This prospective, randomized, single-blinded study enrolled 60 patients, divided into two groups (EOIPB and RSB), each comprising 30 participants
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Helwan University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Abd Elmohsen Bedewy, Helwan University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07601945
- Sponsor's protocol ID
- EOIPB
- Status last verified
- Apr 2026
- First submitted
- 26 Apr 2026
- Last updated
- 22 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 22 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- External Oblique Intercostal Fascial Plane Block Versus Rectus Sheath Block for Postoperative Analgesia After Paraumbilical Hernia Repair Surgery
- ClinicalTrials.gov ID
- NCT07601945
- Acronym / sponsor ID
- EOIPB
- Keywords
- External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block, Pain
- Phase
- Phase 3
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Helwan UniversityUniversity, hospital or other
- Study start
- 1 May 2023 (actual)
- Primary completion
- 30 Apr 2025 (actual)
- Study completion
- 30 Jun 2025 (actual)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty.
Detailed description
Background: Paraumbilical hernia repair is a frequently performed surgical procedure, often associated with significant postoperative pain and delayed recovery, which are major concerns for patients.
Objectives: This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty.
Methods: This prospective, randomized, single-blinded study enrolled 60 patients, divided into two groups (EOIPB and RSB), each comprising 30 participants. Blocks were administered after general anesthesia and prior to surgery. Patient demographics (age, weight), surgical duration, pain scores (measured by Numeric Rating Scale - NRS), total postoperative morphine consumption, intraoperative fentanyl consumption, and hemodynamic parameters (mean arterial pressure - MAP and heart rate - HR) were assessed.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- This prospective, randomized, single-blinded study enrolled 60 patients, divided into two groups (EOIPB and RSB), each comprising 30 participants
| Arm | Type | Receives |
|---|---|---|
| external oblique intercostal fascial plane block | Experimental | Procedure: External Oblique Intercostal Fascial Plane Block for Postoperative Analgesiaexternal oblique intercostal fascial plane block |
| rectus sheath block | Active comparator | Procedure: External Oblique Intercostal Fascial Plane Block for Postoperative Analgesiarectus sheath block |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Patients aged 18-65 years, classified as American Society of Anesthesiologists (ASA) physical status I or II [16], and scheduled for elective paraumbilical hernioplasty.
Key exclusion criteria (1 listed)
- Patients with a history of prolonged opioid medication, allergy to local anesthetics, pregnancy, infection at the injection site, and/or coagulopathy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| External Oblique Intercostal Fascial Plane Block for Postoperative AnalgesiaAfter the induction of general anesthesia and approximately 15 minutes before the surgical incision, patients were randomly assigned to receive either the EOIPB (Group A) or the RSB (Group B). | Procedure or surgery | external oblique intercostal fascial plane block, rectus sheath block |
Primary outcome
Total postoperative morphine consumption in milligrams during the first 24 hours after surgery
Time frame: First 24 hours postoperatively
Total cumulative morphine requirement administered for postoperative analgesia during the first 24 hours following paraumbilical hernia repair surgery, measured in milligrams (mg).
Number of participants experiencing block-related or postoperative complications within 3 months after surgery
Time frame: 3 months after surgery
Assessment of postoperative and block-related complications including local anesthetic toxicity, hematoma, infection, nausea/vomiting, respiratory depression, and other adverse events recorded during the follow-up period.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 May 2026.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A Phase 3 study testing External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia in people with External Oblique Intercostal Fascial Plane Block and Rectus Sheath Block, run by Helwan University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
What does this phase mean?
Phase 3 studies compare the treatment with the current standard treatment or a placebo in a large group, to confirm how well it works and watch for side effects.
Not every study follows the same path, and some studies (observational studies, device studies) have no phase.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Total postoperative morphine consumption in milligrams during the first 24 hours after surgery (time frame: First 24 hours postoperatively). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 May 2026.