Shoulder Pain SyndromeNCT07602478
Eccentric Contraction Exercise For Shoulder Pain Syndrome
A study testing Eccentric Training Protocol and Traditional Physical Therapy Only in people with Shoulder Pain Syndrome and Rotator Cuff Syndrome, run by Rafeef Hassan Asiri at 1 site in Saudi Arabia.
Trial summary
The current study will help to determine the efficacy of a rehabilitation protocol that involves the use of eccentric contraction for patients with shoulder pain syndrome. This approach aims to improve recovery in terms of pain and function based on scientific evidence. Read more about this study
- Who is it for?
- Ages 14 to 70 years
- Conditions the study is for
- Shoulder Pain Syndrome, Rotator Cuff Syndrome, Rotator Cuff Tendonitis
- What is being tested?
- Eccentric Training Protocol and Traditional Physical Therapy Only
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteSaudi Arabia
- Study dates
- 29 Oct 2025to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 70 years
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- 18-70 years old patient, female and male diagnosed with Shoulder pain syndrome and reliable patients who can follow orders.
- Patient diagnosed by rotator cuff tendinitis
Who cannot join
- Patient with VAS more than 8/10
- History of shoulder, cervical, or thoracic surgery, shoulder dislocation, fracture, and labral tear, full thickness rotator cuff tear and adhesive capsulitis, rheumatic disease and / or any medical condition that prevents patient to perform resisted exercises
- Neoplastic disease, and systemic inflammatory disease
- Participants with three positive rotator cuff tear tests were likely to have a full-thickness rotator cuff tear and were excluded from the study.
Trial locations and contacts
1 site in 1 country.
Saudi Arabia1 site
Armed Forces Hospital Southern Region
Khamis Mushait, 'Asir Region, 62413
About this study
Official title: Short-term Effect of Eccentric Contraction Exercises in the Treatment of Patients With Shoulder Pain Syndrome: A Randomized Controlled Trial
The current study will help to determine the efficacy of a rehabilitation protocol that involves the use of eccentric contraction for patients with shoulder pain syndrome. This approach aims to improve recovery in terms of pain and function based on scientific evidence.
- Being tested
- Eccentric Training Protocol, Traditional Physical Therapy Only
- Medical subject headings
- Rotator Cuff Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Eccentric Training ProtocolOther
A 6-week rehabilitation program, conducted for two sessions per week. Patients will receive specialized eccentric contraction exercises for the shoulder muscles, administered in addition to a standard physical therapy protocol.
Traditional Physical Therapy OnlyOther
A 6-week standard rehabilitation program, conducted for two sessions per week. Patients will receive Traditional physical therapy interventions only, which include ultrasound, range of motion (ROM) exercises, postural training and general strengthening routinely prescribed."
| Study group | Role | What they receive |
|---|---|---|
| Eccentric Exercise Group | Experimental | Patients in this group will receive a supervised rehabilitation protocol focusing on eccentric contractions of the shoulder muscles. Receives: Other: Eccentric Training Protocol; Other: Traditional Physical Therapy Only |
| Traditional Physical Therapy Group | Active comparator | Patients in this group will receive traditional physical therapy interventions commonly used for shoulder pain syndrome Receives: Other: Traditional Physical Therapy Only |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change from Baseline in Pain Intensity using the Visual Analog Scale (VAS)
Measured: Baseline and at the end of the 6-week intervention period.
Change from Baseline in Shoulder Pain and Disability using the Shoulder Pain and Disability Index (SPADI)
Measured: Baseline and at the end of the 6-week intervention period.
Secondary outcomes (1)
Change from Baseline in Functional Independence using the Functional Independence Measure (FIM)
Measured: Baseline and at the end of the 6-week intervention period.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study start29 Oct 2025
- Primary completion29 Jan 2026
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Shoulder Pain SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Rafeef Hassan Asiri
- Sponsor type
- Other government
- Responsible party
- Sponsor-investigator, Rafeef Hassan Asiri, Armed Forces Hospitals, Southern Region, Saudi Arabia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07602478
- Sponsor's protocol ID
- H-01-R-096
- Status last verified
- May 2026
- First submitted
- 16 May 2026
- Last updated
- 22 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Alizadehkhaiyat O, Roebuck MM, Makki AT, Frostick SP. POSTURAL ALTERATIONS IN PATIENTS WITH SUBACROMIAL IMPINGEMENT SYNDROME. Int J Sports Phys Ther. 2017 Dec;12(7):1111-1120. doi: 10.26603/ijspt20171111.
PubMed 29234563Gordon F. 'Robert Schumann's mental illnesses. (Genius and madness)', by Mlle Dr Pascal (1908a): Introduction and translation by Felicia Gordon. Hist Psychiatry. 2015 Sep;26(3):359-71. doi: 10.1177/0957154X15589457.
PubMed 26254133Camargo PR, Avila MA, Alburquerque-Sendin F, Asso NA, Hashimoto LH, Salvini TF. Eccentric training for shoulder abductors improves pain, function and isokinetic performance in subjects with shoulder impingement syndrome: a case series. Rev Bras Fisioter. 2012 Jan-Feb;16(1):74-83. doi: 10.1590/s1413-35552012000100013.
PubMed 22441232Kang J, Zhang Z, Wang J, Wang G, Yan Y, Qian H, Zhang X, Xu W, Mao F. hucMSCs Attenuate IBD through Releasing miR148b-5p to Inhibit the Expression of 15-lox-1 in Macrophages. Mediators Inflamm. 2019 May 28;2019:6953963. doi: 10.1155/2019/6953963. eCollection 2019.
PubMed 31275059Shlipak M. Diabetic nephropathy: preventing progression. BMJ Clin Evid. 2010 Jul 8;2010:0606.
PubMed 21418671
Study at a glance
From the registry record, last updated by the sponsor on 22 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Short-term Effect of Eccentric Contraction Exercises in the Treatment of Patients With Shoulder Pain Syndrome: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07602478
- Acronym / sponsor ID
- H-01-R-096
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Rafeef Hassan AsiriOther government
- Study start
- 29 Oct 2025 (actual)
- Primary completion
- 29 Jan 2026 (actual)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The current study will help to determine the efficacy of a rehabilitation protocol that involves the use of eccentric contraction for patients with shoulder pain syndrome. This approach aims to improve recovery in terms of pain and function based on scientific evidence.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Eccentric Exercise Group | Experimental | Other: Eccentric Training Protocol, Other: Traditional Physical Therapy OnlyPatients in this group will receive a supervised rehabilitation protocol focusing on eccentric contractions of the shoulder muscles. |
| Traditional Physical Therapy Group | Active comparator | Other: Traditional Physical Therapy OnlyPatients in this group will receive traditional physical therapy interventions commonly used for shoulder pain syndrome |
Who may qualify
- Ages
- 14 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (2 listed)
- 18-70 years old patient, female and male diagnosed with Shoulder pain syndrome and reliable patients who can follow orders.
- Patient diagnosed by rotator cuff tendinitis
Key exclusion criteria (4 listed)
- Patient with VAS more than 8/10
- History of shoulder, cervical, or thoracic surgery, shoulder dislocation, fracture, and labral tear, full thickness rotator cuff tear and adhesive capsulitis, rheumatic disease and / or any medical condition that prevents patient to perform resisted exercises
- Neoplastic disease, and systemic inflammatory disease
- Participants with three positive rotator cuff tear tests were likely to have a full-thickness rotator cuff tear and were excluded from the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Eccentric Training ProtocolA 6-week rehabilitation program, conducted for two sessions per week. Patients will receive specialized eccentric contraction exercises for the shoulder muscles, administered in addition to a standard physical therapy protocol. | Other | Eccentric Exercise Group |
| Traditional Physical Therapy OnlyA 6-week standard rehabilitation program, conducted for two sessions per week. Patients will receive Traditional physical therapy interventions only, which include ultrasound, range of motion (ROM) exercises, postural training and general strengthening routinely prescribed." | Other | Eccentric Exercise Group, Traditional Physical Therapy Group |
Primary outcome
Change from Baseline in Pain Intensity using the Visual Analog Scale (VAS)
Time frame: Baseline and at the end of the 6-week intervention period.
Change from Baseline in Shoulder Pain and Disability using the Shoulder Pain and Disability Index (SPADI)
Time frame: Baseline and at the end of the 6-week intervention period.
1 secondary outcome
Change from Baseline in Functional Independence using the Functional Independence Measure (FIM)
Time frame: Baseline and at the end of the 6-week intervention period.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 May 2026.
- Background: PubMed 29234563Alizadehkhaiyat O, Roebuck MM, Makki AT, Frostick SP. POSTURAL ALTERATIONS IN PATIENTS WITH SUBACROMIAL IMPINGEMENT SYNDROME. Int J Sports Phys Ther. 2017 Dec;12(7):1111-1120. doi: 10.26603/ijspt20171111.
- Background: PubMed 26254133Gordon F. 'Robert Schumann's mental illnesses. (Genius and madness)', by Mlle Dr Pascal (1908a): Introduction and translation by Felicia Gordon. Hist Psychiatry. 2015 Sep;26(3):359-71. doi: 10.1177/0957154X15589457.
- Background: PubMed 22441232Camargo PR, Avila MA, Alburquerque-Sendin F, Asso NA, Hashimoto LH, Salvini TF. Eccentric training for shoulder abductors improves pain, function and isokinetic performance in subjects with shoulder impingement syndrome: a case series. Rev Bras Fisioter. 2012 Jan-Feb;16(1):74-83. doi: 10.1590/s1413-35552012000100013.
- Background: PubMed 31275059Kang J, Zhang Z, Wang J, Wang G, Yan Y, Qian H, Zhang X, Xu W, Mao F. hucMSCs Attenuate IBD through Releasing miR148b-5p to Inhibit the Expression of 15-lox-1 in Macrophages. Mediators Inflamm. 2019 May 28;2019:6953963. doi: 10.1155/2019/6953963. eCollection 2019.
- Background: PubMed 21418671Shlipak M. Diabetic nephropathy: preventing progression. BMJ Clin Evid. 2010 Jul 8;2010:0606.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Eccentric Training Protocol and Traditional Physical Therapy Only in people with Shoulder Pain Syndrome and Rotator Cuff Syndrome, run by Rafeef Hassan Asiri at 1 site in Saudi Arabia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 22 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Saudi Arabia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change from Baseline in Pain Intensity using the Visual Analog Scale (VAS) (time frame: Baseline and at the end of the 6-week intervention period.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07602478, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 May 2026.