Maxillary SinusNCT07604155
Maxillary Sinus Augmentation Using CAD/CAM Allogenic Bone Blocks Versus Particulate Allogenic Grafts
A study testing sinus lifting using CAD/CAM allogenic block and sinus lifting using particulate allogenic graft in people with Maxillary Sinus and Allograft, run by Tanta University at 1 site in Egypt.
Trial summary
28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups Group I: sinus lifting using CAD/CAM allogenic block through lateral window technique Group II: sinus lifting using particulate allogenic graftthrough lateral window… Read more about this study
- Who is it for?
- Ages 20 years and olderHealthy volunteers can take part
- Conditions the study is for
- Maxillary Sinus, Allograft
- What is being tested?
- sinus lifting using CAD/CAM allogenic block and sinus lifting using particulate allogenic graft
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 28 participants
- Where
- 1 siteEgypt
- Study dates
- 3 Sep 2025to 19 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- above 20 years
- ridge height less than or equal to 5 mm
- healthy clear sinus
Who cannot join
- systemic disease affect bone healing
- heavy smokers
- disease or pathology within the sinus
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Maxillary Sinus Augmentation Using CAD/CAM Customized Allogenic Bone Blocks Versus Particulate Allogenic Grafts for Delayed Implant Placement: A Randomized Clinical Trial
28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups
- Group I: sinus lifting using CAD/CAM allogenic block through lateral window technique
- Group II: sinus lifting using particulate allogenic graftthrough lateral window technique
Read the detailed description
28patients will be included in this study with an atrophic posterior maxillary ridge due to sinus pneumatization, who will be randomly assigned to two groups
- Group I: sinus lifting using CAD/CAM allogenic block through lateral window technique
- Group II: sinus lifting using particulate allogenic graft through the lateral window technique
- Surgical procedure: A full-thickness, wide mucoperiosteal flap was elevated buccally. Alateral bony window of the maxillary sinus will be made then the sinus lining will be elevated carefully. The CAD/CAM allogenic block will be inserted and fixed in its position via a titanium screw to the crest of maxillary ridge (group I). In group II the particulate bone will be packed at the site of augmentation
- The lateral window will be covered with collagen membrane, the flap will reposited in its place and sutured. 6 months later, implants will be inserted
- Conditions
- Maxillary Sinus, Allograft
- Being tested
- sinus lifting using CAD/CAM allogenic block, sinus lifting using particulate allogenic graft
- Keywords
- CAD-CAM allogenic block, particulate allograft, sinus lifting
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
sinus lifting using CAD/CAM allogenic blockProcedure or surgery
A full-thickness, wide mucoperiosteal flap was elevated buccally. A lateral bony window of the maxillary sinus will be made, then the sinus lining will be carefully elevated. The CAD/CAM allogenic block will be inserted and fixed in its position via a titanium screw to the crest of maxillary ridge (group I).
- The lateral window will be covered with collagen membrane, the flap will be repositioned in its place and sutured.
sinus lifting using particulate allogenic graftProcedure or surgery
In group II the particulate bone will packed at the site of augmentation
| Study group | Role | What they receive |
|---|---|---|
| CAD/CAM allogenic block | Experimental | sinus lifting using CAD/CAM allogenic block through lateral window technique Receives: Procedure: sinus lifting using CAD/CAM allogenic block |
| particulate allogenic graft | Experimental | sinus lifting using particulate allogenic graft through lateral window technique Receives: Procedure: sinus lifting using particulate allogenic graft |
What is being measured
The primary outcome is the main question the study is designed to answer.
bone height gain
using CBCT
Measured: 6 months
marginal bone resorption around implants
CBCT
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study start3 Sep 2025
- Primary completion10 Dec 2026 (estimated)
- Study completion19 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Maxillary SinusStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 28 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tanta University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, mona samy sheta, Tanta University
- Investigators
- mohamed h helal, lecturer, Principal investigator, Tanta Universityrehab ghouraba, professor, Principal investigator, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07604155
- Sponsor's protocol ID
- abcd
- Status last verified
- May 2026
- First submitted
- 17 May 2026
- Last updated
- 22 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Maxillary Sinus Augmentation Using CAD/CAM Customized Allogenic Bone Blocks Versus Particulate Allogenic Grafts for Delayed Implant Placement: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07604155
- Acronym / sponsor ID
- abcd
- Conditions
- Maxillary Sinus, Allograft
- Keywords
- CAD-CAM allogenic block, particulate allograft, sinus lifting
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 28 participants (estimated)
- Lead sponsor
- Tanta UniversityUniversity, hospital or other
- Study start
- 3 Sep 2025 (actual)
- Primary completion
- 10 Dec 2026 (estimated)
- Study completion
- 19 Mar 2027 (estimated)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups
- Group I: sinus lifting using CAD/CAM allogenic block through lateral window technique
- Group II: sinus lifting using particulate allogenic graftthrough lateral window technique
Detailed description
28patients will be included in this study with an atrophic posterior maxillary ridge due to sinus pneumatization, who will be randomly assigned to two groups
- Group I: sinus lifting using CAD/CAM allogenic block through lateral window technique
- Group II: sinus lifting using particulate allogenic graft through the lateral window technique
- Surgical procedure: A full-thickness, wide mucoperiosteal flap was elevated buccally. Alateral bony window of the maxillary sinus will be made then the sinus lining will be elevated carefully. The CAD/CAM allogenic block will be inserted and fixed in its position via a titanium screw to the crest of maxillary ridge (group I). In group II the particulate bone will be packed at the site of augmentation
- The lateral window will be covered with collagen membrane, the flap will reposited in its place and sutured. 6 months later, implants will be inserted
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| CAD/CAM allogenic block | Experimental | Procedure: sinus lifting using CAD/CAM allogenic blocksinus lifting using CAD/CAM allogenic block through lateral window technique |
| particulate allogenic graft | Experimental | Procedure: sinus lifting using particulate allogenic graftsinus lifting using particulate allogenic graft through lateral window technique |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- above 20 years
- ridge height less than or equal to 5 mm
- healthy clear sinus
Key exclusion criteria (3 listed)
- systemic disease affect bone healing
- heavy smokers
- disease or pathology within the sinus
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| sinus lifting using CAD/CAM allogenic blockA full-thickness, wide mucoperiosteal flap was elevated buccally. A lateral bony window of the maxillary sinus will be made, then the sinus lining will be carefully elevated. The CAD/CAM allogenic block will be inserted and fixed in its position via a titanium screw to the crest of maxillary ridge (group I). • The lateral window will be covered with collagen membrane, the flap will be repositioned in its place and sutured. | Procedure or surgery | CAD/CAM allogenic block |
| sinus lifting using particulate allogenic graftIn group II the particulate bone will packed at the site of augmentation | Procedure or surgery | particulate allogenic graft |
Primary outcome
bone height gain
Time frame: 6 months
using CBCT
marginal bone resorption around implants
Time frame: 6 months
CBCT
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 May 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
mohamed h helal, lecturer principal investigator
Tanta University
rehab ghouraba, professor principal investigator
Tanta University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing sinus lifting using CAD/CAM allogenic block and sinus lifting using particulate allogenic graft in people with Maxillary Sinus and Allograft, run by Tanta University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 22 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
bone height gain (time frame: 6 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 May 2026.