Periodontal DiseaseNCT07604493
Oral Health and Systemic Diseases: Survey of General Practitioners
An observational study of Periodontal Disease and Diabete Mellitus, run by University of Roma La Sapienza at 1 site in Italy.
Trial summary
This cross-sectional observational study aims to assess the level of knowledge, clinical practices, and professional attitudes of General Practitioners (GPs) regarding oral health and its relationship with major systemic diseases, with particular emphasis on periodontal disease. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Periodontal Disease, Diabete Mellitus
- What is being tested?
- Questionnaire Survey
- Type of treatment
- Pill or oral medicine
- How many people
- 100 participants
- Where
- 1 siteItaly
- Study dates
- 1 Jan 2026to 1 Jan 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The study population will consist of General Practitioners (GPs) currently practicing in Italy. Participants will voluntarily participate after receiving study information and providing informed consent. Eligible participants will complete an anonymous self-administered digital questionnaire designed to assess their knowledge, clinical practices, and professional attitudes regarding oral health and its associations with systemic diseases.
Who may be able to join
- Licensed General Practitioners currently practicing in Italy
- Ability to understand and complete the questionnaire in Italian
- Voluntary agreement to participate after reading study information and providing informed consent
Who cannot join
- Physicians not currently practicing as General Practitioners
- Incomplete questionnaire responses
- Duplicate submissions
- Participants who decline informed consent
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Italy1 site, 1 recruiting
- Recruiting
Sapienza università di Roma
Roma, RM, 00161
Fabrizio Guerra, 3283150627, prof.fabrizio.guerra@gmail.com
About this study
Official title: Oral Health and Systemic Diseases: An Investigative Survey of General Practitioners
This cross-sectional observational study aims to assess the level of knowledge, clinical practices, and professional attitudes of General Practitioners (GPs) regarding oral health and its relationship with major systemic diseases, with particular emphasis on periodontal disease. Data will be collected through an anonymous, self-administered digital questionnaire distributed nationwide to General Practitioners practicing in Italy. The questionnaire will investigate participants' knowledge of oral diseases, awareness of oral-systemic associations, early identification of oral manifestations, educational background, and interdisciplinary collaboration with dental professionals.
Read the detailed description
The aim of this study is to conduct an exploratory survey designed to assess the level of knowledge among General Practitioners (GPs) regarding the main diseases of the oral cavity, particularly dental caries and periodontal diseases, and their associations with systemic conditions, with special attention to autoimmune, dysmetabolic, and cardiovascular diseases.
To achieve this objective, an anonymous questionnaire consisting of 35 questions has been developed, with an estimated completion time of approximately 10-15 minutes. The questionnaire is intended to investigate participants' familiarity with terminology related to periodontal disease, particularly the terms "periodontitis" and "pyorrhea," which are used to describe the same clinical condition, as well as their level of knowledge regarding its manifestations and clinical implications.
The survey will further investigate General Practitioners' ability to recognize oral signs and symptoms potentially associated with local or systemic diseases, as well as the frequency with which these aspects are considered in routine clinical practice and patient assessment. Information will also be collected regarding previous education and training in oral health-related fields and knowledge of major risk factors associated with oral diseases, including smoking, diabetes mellitus, and medications with significant oral health impact.
Analysis of the collected data will provide insight into the extent to which oral health is integrated into general medical practice, highlighting potential educational gaps and challenges in the early recognition of oral alterations. In addition, the study will assess participants' interest in specific educational and continuing professional development initiatives.
The expected findings may contribute to strengthening collaboration between general medicine and dentistry by promoting shared approaches to prevention, screening, and education aimed at achieving a more comprehensive and integrated management of patients, particularly vulnerable populations. Furthermore, the information obtained may provide useful support for the development of preventive strategies and clinical protocols aimed at improving multidisciplinary patient care.
- Conditions
- Periodontal Disease, Diabete Mellitus
- Being tested
- Questionnaire Survey
- Keywords
- smoking, diabetes, periodontitis
- Medical subject headings
- Periodontal Diseases, Diabetes Mellitus, Smoking, Periodontitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Questionnaire SurveyOther
Participants will complete a questionnaire consisting of 35 closed-ended questions designed to assess General Practitioners' knowledge, clinical practices, and attitudes regarding oral health and its relationship with systemic diseases.
| Study group | Role | What they receive |
|---|---|---|
| General Practictioners | General Practictioners currently practicing in Italy Receives: Other: Questionnaire Survey |
What is being measured
The primary outcome is the main question the study is designed to answer.
General Practitioners' level of knowledge regarding oral diseases and oral-systemic associations
Knowledge level will be assessed through a predefined set of questionnaire items investigating participants' understanding of:
- Common oral diseases
- Periodontal disease
- Associations between oral and systemic diseases
- Risk factors and preventive measures The total knowledge score will be calculated by summing the number of correct responses provided by each participant.
Higher total scores will indicate a greater level of knowledge among General Practitioners regarding oral diseases, periodontal disease, oral-systemic associations, risk factors, and oral health-related clinical practices.
Scores may additionally be categorized for descriptive analysis as:
- Low level of knowledge: <50% correct responses
- Moderate level of knowledge: 50-75% correct responses
- High level of knowledge: >75% correct responses
Measured: At questionnaire completion (at baseline)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study start1 Jan 2026
- Primary completion30 Nov 2026 (estimated)
- Study completion1 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Periodontal DiseaseStudies of the same condition, open and under way.
- More trials run by University of Roma La SapienzaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Roma La Sapienza
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fabrizio Guerra, University of Roma La Sapienza
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07604493
- Sponsor's protocol ID
- 3
- Status last verified
- May 2026
- First submitted
- 16 May 2026
- Last updated
- 28 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Oral Health and Systemic Diseases: An Investigative Survey of General Practitioners
- ClinicalTrials.gov ID
- NCT07604493
- Acronym / sponsor ID
- 3
- Conditions
- Periodontal Disease, Diabete Mellitus
- Keywords
- smoking, diabetes, periodontitis
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- University of Roma La SapienzaUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 30 Nov 2026 (estimated)
- Study completion
- 1 Jan 2027 (estimated)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This cross-sectional observational study aims to assess the level of knowledge, clinical practices, and professional attitudes of General Practitioners (GPs) regarding oral health and its relationship with major systemic diseases, with particular emphasis on periodontal disease. Data will be collected through an anonymous, self-administered digital questionnaire distributed nationwide to General Practitioners practicing in Italy. The questionnaire will investigate participants' knowledge of oral diseases, awareness of oral-systemic associations, early identification of oral manifestations, educational background, and interdisciplinary collaboration with dental professionals.
Detailed description
The aim of this study is to conduct an exploratory survey designed to assess the level of knowledge among General Practitioners (GPs) regarding the main diseases of the oral cavity, particularly dental caries and periodontal diseases, and their associations with systemic conditions, with special attention to autoimmune, dysmetabolic, and cardiovascular diseases.
To achieve this objective, an anonymous questionnaire consisting of 35 questions has been developed, with an estimated completion time of approximately 10-15 minutes. The questionnaire is intended to investigate participants' familiarity with terminology related to periodontal disease, particularly the terms "periodontitis" and "pyorrhea," which are used to describe the same clinical condition, as well as their level of knowledge regarding its manifestations and clinical implications.
The survey will further investigate General Practitioners' ability to recognize oral signs and symptoms potentially associated with local or systemic diseases, as well as the frequency with which these aspects are considered in routine clinical practice and patient assessment. Information will also be collected regarding previous education and training in oral health-related fields and knowledge of major risk factors associated with oral diseases, including smoking, diabetes mellitus, and medications with significant oral health impact.
Analysis of the collected data will provide insight into the extent to which oral health is integrated into general medical practice, highlighting potential educational gaps and challenges in the early recognition of oral alterations. In addition, the study will assess participants' interest in specific educational and continuing professional development initiatives.
The expected findings may contribute to strengthening collaboration between general medicine and dentistry by promoting shared approaches to prevention, screening, and education aimed at achieving a more comprehensive and integrated management of patients, particularly vulnerable populations. Furthermore, the information obtained may provide useful support for the development of preventive strategies and clinical protocols aimed at improving multidisciplinary patient care.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| General Practictioners | – | Other: Questionnaire SurveyGeneral Practictioners currently practicing in Italy |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The study population will consist of General Practitioners (GPs) currently practicing in Italy. Participants will voluntarily participate after receiving study information and providing informed consent. Eligible participants will complete an anonymous self-administered digital questionnaire designed to assess their knowledge, clinical practices, and professional attitudes regarding oral health and its associations with systemic diseases.
Key inclusion criteria (3 listed)
- Licensed General Practitioners currently practicing in Italy
- Ability to understand and complete the questionnaire in Italian
- Voluntary agreement to participate after reading study information and providing informed consent
Key exclusion criteria (4 listed)
- Physicians not currently practicing as General Practitioners
- Incomplete questionnaire responses
- Duplicate submissions
- Participants who decline informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Questionnaire SurveyParticipants will complete a questionnaire consisting of 35 closed-ended questions designed to assess General Practitioners' knowledge, clinical practices, and attitudes regarding oral health and its relationship with systemic diseases. | Other | General Practictioners |
Primary outcome
General Practitioners' level of knowledge regarding oral diseases and oral-systemic associations
Time frame: At questionnaire completion (at baseline)
Knowledge level will be assessed through a predefined set of questionnaire items investigating participants' understanding of: * Common oral diseases * Periodontal disease * Associations between oral and systemic diseases * Risk factors and preventive measures The total knowledge score will be calculated by summing the number of correct responses provided by each participant. Higher total scores will indicate a greater level of knowledge among General Practitioners regarding oral diseases, periodontal disease, oral-systemic associations, risk factors, and oral health-related clinical practices. Scores may additionally be categorized for descriptive analysis as: * Low level of knowledge: <50% correct responses * Moderate level of knowledge: 50-75% correct responses * High level of knowledge: >75% correct responses
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 May 2026.
- Individual participant dataSharing planned: No
Related trials for Periodontal Disease
Not yet recruitingObservational study
Periodontal Status and Biomarkers in MASLD
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Recruiting
Thermosensitive Hyaluronic Gel With Octenidine as an Adjunctive to Subgingival Instrumentation
Periodontal Disease
Active, not recruitingObservational study
A Retrospective Comparative Evaluation of Omega-3 and Resveratrol Supplementation in Patients With Periodontitis
Periodontitis
Recruiting
Effects of Different Activation Techniques on Antimicrobial Photodynamic Therapy in Apical Periodontitis
Apical Periodontitis, Endodontic Retreatment
Recruiting
Ozone Gel Versus Chlorohexidine Gel as an Adjunct to Non-Surgical Treatment of Stage II Periodontitis Grade B Among Smokers Patients
Ozone Gel, Chlorohexidine Gel
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Periodontal Disease and Diabete Mellitus, run by University of Roma La Sapienza at 1 site in Italy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Fabrizio Guerra (3283150627, fabrizio.guerra@uniroma1.it), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
General Practitioners' level of knowledge regarding oral diseases and oral-systemic associations (time frame: At questionnaire completion (at baseline)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 May 2026.