Synechia After DCRNCT07605026
Endoscopic DCR With and Without Internal Nasal Splint
A study testing Endoscopic DCR with putting internal nasal splint and Endoscopic DCR without putting internal nasal splint in people with Synechia After DCR, run by Kafrelsheikh University at 1 site in Egypt.
Trial summary
This study aims to compare the outcomes of endoscopic DCR performed with versus without internal nasal splints, by assessing functional outcomes, complication rates, and overall success rates. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Synechia After DCR
- What is being tested?
- Endoscopic DCR with putting internal nasal splint and Endoscopic DCR without putting internal nasal splint
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 150 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Jan 2024to 3 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age >18 years. Symptomatic NLDO (epiphora, recurrent dacryocystitis). Fit for general anesthesia
Who cannot join
- Congenital dacryocystitis. Canalicular or punctal obstruction. Previous lacrimal surgery. Post-traumatic or post-radiation epiphora. Coexisting nasal pathology (tumors, granulomatous disease, atrophic rhinitis). Immunocompromised or uncontrolled systemic disease. Patients unwilling to undergo endoscopic surgery.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Endonasal Endoscopic Dacryocystorhinostomy With and Without Internal Nasal Splint-A Comparative Study
This study aims to compare the outcomes of endoscopic DCR performed with versus without internal nasal splints, by assessing functional outcomes, complication rates, and overall success rates.
- Conditions
- Synechia After DCR
- Being tested
- Endoscopic DCR with putting internal nasal splint, Endoscopic DCR without putting internal nasal splint
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Endoscopic DCR with putting internal nasal splintProcedure or surgery
Patients will undergo Endoscopic DCR with putting internal nasal splint between middle turbinate and middle meatus
Endoscopic DCR without putting internal nasal splintProcedure or surgery
Patients will undergo Endoscopic DCR without putting internal nasal splint between middle turbinate and middle meatus
| Study group | Role | What they receive |
|---|---|---|
| Endoscopic DCR with internal nasal splint | Active comparator | Patients will undergo Endoscopic DCR with putting internal nasal splint between middle turbinate and middle meatus Receives: Procedure: Endoscopic DCR with putting internal nasal splint |
| Endoscopic DCR without internal nasal splint. | Active comparator | Patients will undergo Endoscopic DCR without putting internal nasal splint between middle turbinate and middle meatus Receives: Procedure: Endoscopic DCR without putting internal nasal splint |
What is being measured
The primary outcome is the main question the study is designed to answer.
Success rates as Stomal patency , absence of formation of synechia and cessation of epiphora.
Measured: Evaluation will be done by nasal endoscopic examination of the middle meatus after 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study start15 Jan 2024
- Primary completion5 Jun 2025
- Study completion3 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Synechia After DCRStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 150 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kafrelsheikh University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Magdi Noaman Othman Orabi, Kafrelsheikh University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07605026
- Sponsor's protocol ID
- KFSIRB200-799
- Status last verified
- May 2026
- First submitted
- 17 May 2026
- Last updated
- 22 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 22 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Endonasal Endoscopic Dacryocystorhinostomy With and Without Internal Nasal Splint-A Comparative Study
- ClinicalTrials.gov ID
- NCT07605026
- Acronym / sponsor ID
- KFSIRB200-799
- Conditions
- Synechia After DCR
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 150 participants (actual)
- Lead sponsor
- Kafrelsheikh UniversityUniversity, hospital or other
- Study start
- 15 Jan 2024 (actual)
- Primary completion
- 5 Jun 2025 (actual)
- Study completion
- 3 Jul 2025 (actual)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the outcomes of endoscopic DCR performed with versus without internal nasal splints, by assessing functional outcomes, complication rates, and overall success rates.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Endoscopic DCR with internal nasal splint | Active comparator | Procedure: Endoscopic DCR with putting internal nasal splintPatients will undergo Endoscopic DCR with putting internal nasal splint between middle turbinate and middle meatus |
| Endoscopic DCR without internal nasal splint. | Active comparator | Procedure: Endoscopic DCR without putting internal nasal splintPatients will undergo Endoscopic DCR without putting internal nasal splint between middle turbinate and middle meatus |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Age >18 years. Symptomatic NLDO (epiphora, recurrent dacryocystitis). Fit for general anesthesia
Key exclusion criteria (1 listed)
- Congenital dacryocystitis. Canalicular or punctal obstruction. Previous lacrimal surgery. Post-traumatic or post-radiation epiphora. Coexisting nasal pathology (tumors, granulomatous disease, atrophic rhinitis). Immunocompromised or uncontrolled systemic disease. Patients unwilling to undergo endoscopic surgery.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Endoscopic DCR with putting internal nasal splintPatients will undergo Endoscopic DCR with putting internal nasal splint between middle turbinate and middle meatus | Procedure or surgery | Endoscopic DCR with internal nasal splint |
| Endoscopic DCR without putting internal nasal splintPatients will undergo Endoscopic DCR without putting internal nasal splint between middle turbinate and middle meatus | Procedure or surgery | Endoscopic DCR without internal nasal splint. |
Primary outcome
Success rates as Stomal patency , absence of formation of synechia and cessation of epiphora.
Time frame: Evaluation will be done by nasal endoscopic examination of the middle meatus after 1 month
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 May 2026.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Endoscopic DCR with putting internal nasal splint and Endoscopic DCR without putting internal nasal splint in people with Synechia After DCR, run by Kafrelsheikh University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Success rates as Stomal patency , absence of formation of synechia and cessation of epiphora. (time frame: Evaluation will be done by nasal endoscopic examination of the middle meatus after 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 May 2026.