Renal CalculiNCT07610252
Comparison of Extracorporeal Shock Wave Lithotripsy (ESWL) and Ultra-mini Percutaneous Nephrolithotomy (PCNI), in Renal Stones <20 mm.
A study testing Ultra-mini PCNL and Extracorporeal shock wave lithotripsy in people with Renal Calculi, run by Muhammad Aamir Latif at 1 site in Pakistan.
Trial summary
There is a dearth of information comparing ultra-mini PNCL with ESWI in Pakistan for kidney stones smaller than 20 mm. Hence the current study was planned with the objective of comparing the outcome of ESWL and ultra-mini PCNL in renal stones less than 20 mm. Read more about this study
- Who is it for?
- Ages 20 to 60 years
- Conditions the study is for
- Renal Calculi
- What is being tested?
- Ultra-mini PCNL and Extracorporeal shock wave lithotripsy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 138 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Jul 2025to 31 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients of any gender
- Aged 20-60 years
- With a single kidney stone in renal pelvis smaller than 20 mm
Who cannot join
- Pregnancy
- Hemorrhage problems
- Sepsis and pyonephrosis
- With pelvic kidneys
- Obstruction of the pelvi-ureteric junction
- Chronic illness (chronic liver disease, chronic renal failure, chronic drug use)
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Bahawal Victoria Hospital/Quaid-e-Azam Medical College
Bahawalpur, Punjab Province, 63100
About this study
Official title: Comparison of the Outcome of Extracorporeal Shock Wave Lithotripsy (ESWL) and Ultra-mini Percutaneous Nephrolithotomy (PCNL), in Renal Stones <20 mm.
There is a dearth of information comparing ultra-mini PNCL with ESWI in Pakistan for kidney stones smaller than 20 mm. Hence the current study was planned with the objective of comparing the outcome of ESWL and ultra-mini PCNL in renal stones less than 20 mm.
Read the detailed description
Even though small PCNL and ESWL are tried-and-true techniques for kidney calculus, their usage poses unique challenges since they need precision to guarantee effective stone removal while minimizing invasiveness. Despite these advantages, selecting the optimum course of action is challenging due to risks of both modalities. The results of this investigation would therefore help to improve the treatment of the patients with renal proximal stones that are smaller than 20 mm.
- Conditions
- Renal Calculi
- Being tested
- Ultra-mini PCNL, Extracorporeal shock wave lithotripsy
- Medical subject headings
- Kidney Calculi
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultra-mini PCNLProcedure or surgery
Patients were treated with ultra-mini PCNL with DJ stent implantation.
Extracorporeal shock wave lithotripsyProcedure or surgery
Extracorporeal shock wave lithotripsy (ESWL) with DJ stent implantation was performed in patients. Typically, the therapy began with a lower power of 1 kV and was progressively increased to 20 kV. Each session included no more than 2000 shocks.
| Study group | Role | What they receive |
|---|---|---|
| Group-A | Experimental | Patients were treated with ultra-mini PCNL with double J stent implantation. Receives: Procedure: Ultra-mini PCNL |
| Group-B | Experimental | Extracorporeal shock wave lithotripsy (ESWL) with double J stent implantation was performed in patients. Typically, the therapy began with a lower power of 1 kilovolt (kV) and was progressively increased to 20 kV. Each session included no more than 2000 shocks. Receives: Procedure: Extracorporeal shock wave lithotripsy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Stone clearance
The frequency of the patients with full stone clearance was noted and cmpared between the groups.
Measured: 4 weeks
Urinary tract infection
The frequency of patients reported with urinary tract infection was noted and compared between the groups.
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 May 2026
- Study start1 Jul 2025
- Primary completion31 Dec 2025
- Study completion31 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Renal CalculiStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 138 participants (actual)
Sponsor and investigators
- Lead sponsor
- Muhammad Aamir Latif
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Muhammad Aamir Latif, RESnTEC, Institute of Research
- Investigators
- Muhammad Saleem, Principal investigator, Bahawal Victoria Hospital/Quid-e-Azam Medical College, BahawalpurMumtaz Rasool, FCPS, Study director, Bahawal Victoria Hospital/Quaid-e-Azam Medical College, Bahawalpur
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07610252
- Sponsor's protocol ID
- Dr-Saleem-BVH
- Status last verified
- May 2026
- First submitted
- 20 May 2026
- Last updated
- 27 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Data can be shared on a reasonable request.
Study at a glance
From the registry record, last updated by the sponsor on 27 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Outcome of Extracorporeal Shock Wave Lithotripsy (ESWL) and Ultra-mini Percutaneous Nephrolithotomy (PCNL), in Renal Stones <20 mm.
- ClinicalTrials.gov ID
- NCT07610252
- Acronym / sponsor ID
- Dr-Saleem-BVH
- Conditions
- Renal Calculi
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 138 participants (actual)
- Lead sponsor
- Muhammad Aamir LatifUniversity, hospital or other
- Study start
- 1 Jul 2025 (actual)
- Primary completion
- 31 Dec 2025 (actual)
- Study completion
- 31 Dec 2025 (actual)
- First posted
- 27 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
There is a dearth of information comparing ultra-mini PNCL with ESWI in Pakistan for kidney stones smaller than 20 mm. Hence the current study was planned with the objective of comparing the outcome of ESWL and ultra-mini PCNL in renal stones less than 20 mm.
Detailed description
Even though small PCNL and ESWL are tried-and-true techniques for kidney calculus, their usage poses unique challenges since they need precision to guarantee effective stone removal while minimizing invasiveness. Despite these advantages, selecting the optimum course of action is challenging due to risks of both modalities. The results of this investigation would therefore help to improve the treatment of the patients with renal proximal stones that are smaller than 20 mm.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group-A | Experimental | Procedure: Ultra-mini PCNLPatients were treated with ultra-mini PCNL with double J stent implantation. |
| Group-B | Experimental | Procedure: Extracorporeal shock wave lithotripsyExtracorporeal shock wave lithotripsy (ESWL) with double J stent implantation was performed in patients. Typically, the therapy began with a lower power of 1 kilovolt (kV) and was progressively increased to 20 kV. Each session included no more than 2000 shocks. |
Who may qualify
- Ages
- 20 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Patients of any gender
- Aged 20-60 years
- With a single kidney stone in renal pelvis smaller than 20 mm
Key exclusion criteria (6 listed)
- Pregnancy
- Hemorrhage problems
- Sepsis and pyonephrosis
- With pelvic kidneys
- Obstruction of the pelvi-ureteric junction
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultra-mini PCNLPatients were treated with ultra-mini PCNL with DJ stent implantation. | Procedure or surgery | Group-A |
| Extracorporeal shock wave lithotripsyExtracorporeal shock wave lithotripsy (ESWL) with DJ stent implantation was performed in patients. Typically, the therapy began with a lower power of 1 kV and was progressively increased to 20 kV. Each session included no more than 2000 shocks. | Procedure or surgery | Group-B |
Primary outcome
Stone clearance
Time frame: 4 weeks
The frequency of the patients with full stone clearance was noted and cmpared between the groups.
Urinary tract infection
Time frame: 4 weeks
The frequency of patients reported with urinary tract infection was noted and compared between the groups.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 May 2026.
- Individual participant dataSharing planned: No. Data can be shared on a reasonable request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Muhammad Saleem principal investigator
Bahawal Victoria Hospital/Quid-e-Azam Medical College, Bahawalpur
Mumtaz Rasool, FCPS study director
Bahawal Victoria Hospital/Quaid-e-Azam Medical College, Bahawalpur
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultra-mini PCNL and Extracorporeal shock wave lithotripsy in people with Renal Calculi, run by Muhammad Aamir Latif at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Stone clearance (time frame: 4 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 May 2026.