StrokeNCT07612397
Effects of Jaw Clenching on Gait and Mobility in Stroke
A study testing Voluntary Jaw Clenching in people with Stroke, run by Bitlis Eren University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to investigate the immediate effects of jaw clenching on gait and functional mobility in patients with chronic stroke. Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Stroke
- What is being tested?
- Voluntary Jaw Clenching
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 30 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- Dec 2026to Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Stroke occurred at least 6 months prior to enrollment.
- No cognitive or communication impairments that would interfere with participation.
- Ability to stand independently for 20 seconds or more.
- Ability to walk 10 meters independently, with or without walking aids or orthoses as needed.
- Age between 18 and 75 years.
- Lower extremity Brunnstrom stage of 4 or higher.
Who cannot join
- Presence of severe osteoarthritis in the lower extremities.
- Diagnosis of cancer or diabetic neuropathy.
- Presence of vestibular disorders.
- Lower extremity ulceration or amputation.
- History of vertigo.
- Alcohol consumption within the past 24 hours.
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- Hemodynamic instability.
- Stroke affecting the basilar artery or cerebellum (posterior circulation stroke).
- Presence of neurological disorders such as multiple sclerosis or Parkinson's disease.
- Acute lower extremity injury within the past 6 weeks.
- History of lower extremity surgery.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Bolu İzzet Baysal Fizik Tedavi ve Rehabilitasyon Eğitim ve Araştırma Hastanesi
Bolu, Merkez, 14280
Ahmet Mavuş, M.Sc., 5388178351 ext. +90, a.burakmavus@gmail.com
About this study
Official title: Immediate Effects of Jaw Clenching on Gait and Functional Mobility in Patients With Chronic Stroke
The aim of this study is to investigate the immediate effects of jaw clenching on gait and functional mobility in patients with chronic stroke.
Read the detailed description
This randomized sham-controlled crossover study aims to investigate the immediate effects of jaw clenching on gait and functional mobility in patients with chronic stroke. A minimum of 30 eligible patients will be included. Each participant will complete both the intervention and sham conditions in a randomized sequence.
- Conditions
- Stroke
- Being tested
- Voluntary Jaw Clenching, Sham Cotton Roll Placement Without Clenching
- Keywords
- Jaw clenching, Gait
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Voluntary Jaw ClenchingOther
In this group, 1-cm-thick cotton rolls will be placed bilaterally on the occlusal surfaces, and patients will be instructed to perform maximal voluntary tooth clenching.
Sham Cotton Roll Placement Without ClenchingOther
In this group, 1-cm-thick cotton rolls will be placed bilaterally on the occlusal surfaces without any clenching instruction, and participants will be instructed to keep their jaw relaxed.
| Study group | Role | What they receive |
|---|---|---|
| Voluntary Jaw Clenching | Experimental | Participants will perform maximal voluntary jaw clenching with bilateral dental cotton rolls placed on the occlusal surfaces. Receives: Other: Voluntary Jaw Clenching |
| Sham Cotton Roll Placement Without Clenching | Sham comparator | Participants will receive the same bilateral dental cotton roll positioning on the occlusal surfaces without performing jaw clenching. Receives: Other: Sham Cotton Roll Placement Without Clenching |
What is being measured
The primary outcome is the main question the study is designed to answer.
Timed Up and Go (TUG) Test
Functional mobility will be assessed using the Timed Up and Go (TUG) Test. Participants will be timed while rising from a chair, walking 3 meters, turning, walking back, and sitting down. Lower scores indicate better functional mobility.
Measured: Baseline and immediately post-intervention for both experimental and sham conditions
10-Meter Walk Test (10MWT)
Gait speed will be assessed using the 10-Meter Walk Test. Participants will be instructed to walk a 10-meter distance at a comfortable walking speed, and time will be recorded to calculate walking velocity.
Measured: Baseline and immediately post-intervention for both experimental and sham conditions
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 May 2026
- Study startDec 2026 (estimated)
- Primary completionJan 2027 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Bitlis Eren University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Merve Tunçdemir, Bitlis Eren University
- Investigators
- Merve Tunçdemir, Principal investigator, Bitlis Eren UniversityÖmer Dursun, Principal investigator, Bitlis Eren UniversityAhmet Burak Mavuş, M.Sc., Principal investigator, Bolu Abant İzzet Baysal Physiotherapy and Rehabilitation Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07612397
- Sponsor's protocol ID
- Beuftr_3
- Status last verified
- Oct 2026
- First submitted
- 19 Apr 2026
- Last updated
- 3 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Immediate Effects of Jaw Clenching on Gait and Functional Mobility in Patients With Chronic Stroke
- ClinicalTrials.gov ID
- NCT07612397
- Acronym / sponsor ID
- Beuftr_3
- Conditions
- Stroke
- Keywords
- Jaw clenching, Gait
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Bitlis Eren UniversityUniversity, hospital or other
- Study start
- Dec 2026 (estimated)
- Primary completion
- Jan 2027 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 28 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the immediate effects of jaw clenching on gait and functional mobility in patients with chronic stroke.
Detailed description
This randomized sham-controlled crossover study aims to investigate the immediate effects of jaw clenching on gait and functional mobility in patients with chronic stroke. A minimum of 30 eligible patients will be included. Each participant will complete both the intervention and sham conditions in a randomized sequence.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Voluntary Jaw Clenching | Experimental | Other: Voluntary Jaw ClenchingParticipants will perform maximal voluntary jaw clenching with bilateral dental cotton rolls placed on the occlusal surfaces. |
| Sham Cotton Roll Placement Without Clenching | Sham comparator | Other: Sham Cotton Roll Placement Without ClenchingParticipants will receive the same bilateral dental cotton roll positioning on the occlusal surfaces without performing jaw clenching. |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Stroke occurred at least 6 months prior to enrollment.
- No cognitive or communication impairments that would interfere with participation.
- Ability to stand independently for 20 seconds or more.
- Ability to walk 10 meters independently, with or without walking aids or orthoses as needed.
- Age between 18 and 75 years.
Key exclusion criteria (11 listed)
- Presence of severe osteoarthritis in the lower extremities.
- Diagnosis of cancer or diabetic neuropathy.
- Presence of vestibular disorders.
- Lower extremity ulceration or amputation.
- History of vertigo.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Voluntary Jaw ClenchingIn this group, 1-cm-thick cotton rolls will be placed bilaterally on the occlusal surfaces, and patients will be instructed to perform maximal voluntary tooth clenching. | Other | Voluntary Jaw Clenching |
| Sham Cotton Roll Placement Without ClenchingIn this group, 1-cm-thick cotton rolls will be placed bilaterally on the occlusal surfaces without any clenching instruction, and participants will be instructed to keep their jaw relaxed. | Other | Sham Cotton Roll Placement Without Clenching |
Primary outcome
Timed Up and Go (TUG) Test
Time frame: Baseline and immediately post-intervention for both experimental and sham conditions
Functional mobility will be assessed using the Timed Up and Go (TUG) Test. Participants will be timed while rising from a chair, walking 3 meters, turning, walking back, and sitting down. Lower scores indicate better functional mobility.
10-Meter Walk Test (10MWT)
Time frame: Baseline and immediately post-intervention for both experimental and sham conditions
Gait speed will be assessed using the 10-Meter Walk Test. Participants will be instructed to walk a 10-meter distance at a comfortable walking speed, and time will be recorded to calculate walking velocity.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2026.
Related trials for Stroke
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Temporal Interference Stimulation for Upper-Limb Motor Recovery in Early Subacute Stroke
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Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
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Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Subarachnoid Aneurysm Hemorrhage
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Selective Intra-Arterial Hypothermia After Endovascular Treatment for Acute Basilar Artery Occlusion
Acute Ischemic Stroke, Basilar Artery Occlusion
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Merve Tunçdemir principal investigator
Bitlis Eren University
Ömer Dursun principal investigator
Bitlis Eren University
Ahmet Burak Mavuş, M.Sc. principal investigator
Bolu Abant İzzet Baysal Physiotherapy and Rehabilitation Training and Research Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Voluntary Jaw Clenching in people with Stroke, run by Bitlis Eren University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 3 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Merve Tunçdemir, Asst. Prof. (5069452008 ext. +90, merve.kd@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Timed Up and Go (TUG) Test (time frame: Baseline and immediately post-intervention for both experimental and sham conditions). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2026.