Hip FractureMETA-SIFINCT07612761
Comparison of Meta-PENG and Suprainguinal Fascia Iliaca Plane Block in Hip Fractures
An observational study of Hip Fracture and Postoperative Pain, run by Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
This prospective observational single-center study will compare the effects of ultrasound-guided meta-PENG block and suprainguinal fascia iliaca plane block in patients undergoing hip fracture surgery under spinal anesthesia. Hip fracture surgery can cause significant pain before, during, and after the operation. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hip Fracture, Postoperative Pain, Regional Anesthesia
- What is being tested?
- Ultrasound-Guided Meta-PENG Block and Ultrasound-Guided Suprainguinal Fascia Iliaca Plane Block
- Type of treatment
- Surgery or procedure
- How many people
- 80 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 14 May 2026to 31 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients scheduled to undergo hip fracture surgery under spinal anesthesia at Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital will be included. Eligible patients will be ASA physical status I-III and will receive either ultrasound-guided meta-PENG block or ultrasound-guided suprainguinal fascia iliaca plane block as part of routine perioperative analgesia management.
Who may be able to join
- Age greater than 18 years
- ASA physical status I-III
- Scheduled to undergo hip fracture surgery under spinal anesthesia
- Written informed consent obtained from the patient or the patient's legal representative
Who cannot join
- Refusal to participate in the study
- ASA physical status IV-V
- Presence of central or autonomic nervous system disease
- Known allergy to the drugs used in the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Şule Altuncu, MD contact
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital
Istanbul, Istanbul, 34000
Sule Altuncu, MD, +90 216 606 33 00, sule.621@hotmail.com
About this study
Official title: Comparison of the Effects of Ultrasound-Guided Meta-PENG Block and Suprainguinal Fascia Iliaca Plane Block in Patients Undergoing Hip Fracture Surgery Under Spinal Anesthesia
This prospective observational single-center study will compare the effects of ultrasound-guided meta-PENG block and suprainguinal fascia iliaca plane block in patients undergoing hip fracture surgery under spinal anesthesia.
Hip fracture surgery can cause significant pain before, during, and after the operation. Regional anesthesia techniques may help reduce pain, improve positioning for spinal anesthesia, decrease the need for additional analgesics, and support earlier mobilization.
Read more
Patients included in the study will be adults scheduled for hip fracture surgery under spinal anesthesia. According to routine clinical practice and the anesthesiologist's decision, patients will receive either ultrasound-guided meta-PENG block or ultrasound-guided suprainguinal fascia iliaca plane block. The study will not assign patients to a treatment group by randomization.
The main outcome will be pain during positioning for spinal anesthesia, measured using the Numeric Rating Scale. Additional outcomes will include postoperative pain at rest and during activity, additional analgesic consumption, patient satisfaction, mobilization time, and length of hospital stay.
Read the detailed description
Hip fractures are common, especially in older adults, and are associated with significant perioperative pain, delayed mobilization, increased analgesic requirements, and prolonged hospitalization. Effective perioperative pain control is important in this patient population because inadequate analgesia may impair positioning for spinal anesthesia, increase postoperative discomfort, and delay recovery.
Regional anesthesia techniques are frequently used as part of multimodal analgesia in patients undergoing hip fracture surgery. The suprainguinal fascia iliaca plane block is a regional block technique that may provide analgesia by affecting nerves related to the lumbar plexus, including the femoral nerve, lateral femoral cutaneous nerve, and obturator nerve. The pericapsular nerve group block and modified techniques, including meta-PENG block, aim to provide analgesia by targeting articular branches involved in hip joint innervation.
This study is designed as a prospective observational single-center study. Adult patients with ASA physical status I-III who are scheduled to undergo hip fracture surgery under spinal anesthesia will be evaluated for eligibility. Patients who provide written informed consent, or whose legal representative provides consent when applicable, will be included.
The regional block technique will be determined according to routine clinical practice and the responsible anesthesiologist's preference. Patients will not be randomized by the study protocol. Patients will be observed in two groups: those receiving ultrasound-guided meta-PENG block and those receiving ultrasound-guided suprainguinal fascia iliaca plane block.
The primary outcome of the study is pain during positioning for spinal anesthesia. Pain will be assessed using the Numeric Rating Scale, where 0 indicates no pain and 10 indicates the worst imaginable pain.
Secondary outcomes will include postoperative Numeric Rating Scale scores at rest and during activity, including back raising and hip flexion; additional analgesic consumption; patient satisfaction assessed using the OR-15 questionnaire; time to mobilization; and length of hospital stay.
Intraoperative data, spinal anesthesia medication dose, regional block and anesthesia methods, postoperative pain scores, additional analgesic requirements, mobilization time, patient satisfaction, and hospitalization duration will be recorded from the hospital information system and anesthesia records.
The study will be conducted at Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital. The study has been reviewed and approved by the institutional scientific research ethics committee.
- Conditions
- Hip Fracture, Postoperative Pain, Regional Anesthesia
- Being tested
- Ultrasound-Guided Meta-PENG Block, Ultrasound-Guided Suprainguinal Fascia Iliaca Plane Block
- Keywords
- Hip fracture, Meta-PENG block, Suprainguinal fascia iliaca plane block, Postoperative analgesia, Regional anesthesia
- Medical subject headings
- Hip Fractures, Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound-Guided Meta-PENG BlockProcedure or surgery
Ultrasound-guided meta-PENG block performed as part of routine perioperative regional analgesia management in patients undergoing hip fracture surgery under spinal anesthesia.
Ultrasound-Guided Suprainguinal Fascia Iliaca Plane BlockProcedure or surgery
Ultrasound-guided suprainguinal fascia iliaca plane block performed as part of routine perioperative regional analgesia management in patients undergoing hip fracture surgery under spinal anesthesia.
| Study group | Role | What they receive |
|---|---|---|
| Meta-PENG Block Group | Patients undergoing hip fracture surgery under spinal anesthesia who receive ultrasound-guided meta-PENG block as part of routine perioperative analgesia management. Receives: Procedure: Ultrasound-Guided Meta-PENG Block | |
| Suprainguinal Fascia Iliaca Plane Block Group | Patients undergoing hip fracture surgery under spinal anesthesia who receive ultrasound-guided suprainguinal fascia iliaca plane block as part of routine perioperative analgesia management. Receives: Procedure: Ultrasound-Guided Suprainguinal Fascia Iliaca Plane Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain During Positioning for Spinal Anesthesia
Pain intensity during positioning for spinal anesthesia will be assessed using the Numeric Rating Scale. The Numeric Rating Scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain.
Measured: During the positioning for spinal anesthesia, immediately before spinal needle insertion(Periprocedural)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 May 2026
- Study start14 May 2026
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Hip FractureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Sule Altuncu, MD, Principal investigator, Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07612761
- Sponsor's protocol ID
- 2026-273
- Acronym
- META-SIFI
- Status last verified
- May 2026
- First submitted
- 19 May 2026
- Last updated
- 29 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared because the study includes patient clinical data and no data sharing plan was specified in the approved study protocol.
Publications
Pai P, Amor D, Lai YH, Echevarria GC. Use and Clinical Relevancy of Pericapsular Nerve Block (PENG) in Total Hip Arthroplasty: A Systematic Review and Meta-analysis. Clin J Pain. 2024 May 1;40(5):320-332. doi: 10.1097/AJP.0000000000001196.
PubMed 38268183Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847.
PubMed 30063657
Study at a glance
From the registry record, last updated by the sponsor on 29 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effects of Ultrasound-Guided Meta-PENG Block and Suprainguinal Fascia Iliaca Plane Block in Patients Undergoing Hip Fracture Surgery Under Spinal Anesthesia
- ClinicalTrials.gov ID
- NCT07612761
- Acronym / sponsor ID
- META-SIFI / 2026-273
- Conditions
- Hip Fracture, Postoperative Pain, Regional Anesthesia
- Keywords
- Hip fracture, Meta-PENG block, Suprainguinal fascia iliaca plane block, Postoperative analgesia, Regional anesthesia
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research HospitalUniversity, hospital or other
- Study start
- 14 May 2026 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 29 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective observational single-center study will compare the effects of ultrasound-guided meta-PENG block and suprainguinal fascia iliaca plane block in patients undergoing hip fracture surgery under spinal anesthesia.
Hip fracture surgery can cause significant pain before, during, and after the operation. Regional anesthesia techniques may help reduce pain, improve positioning for spinal anesthesia, decrease the need for additional analgesics, and support earlier mobilization.
Patients included in the study will be adults scheduled for hip fracture surgery under spinal anesthesia. According to routine clinical practice and the anesthesiologist's decision, patients will receive either ultrasound-guided meta-PENG block or ultrasound-guided suprainguinal fascia iliaca plane block. The study will not assign patients to a treatment group by randomization.
The main outcome will be pain during positioning for spinal anesthesia, measured using the Numeric Rating Scale. Additional outcomes will include postoperative pain at rest and during activity, additional analgesic consumption, patient satisfaction, mobilization time, and length of hospital stay.
Detailed description
Hip fractures are common, especially in older adults, and are associated with significant perioperative pain, delayed mobilization, increased analgesic requirements, and prolonged hospitalization. Effective perioperative pain control is important in this patient population because inadequate analgesia may impair positioning for spinal anesthesia, increase postoperative discomfort, and delay recovery.
Regional anesthesia techniques are frequently used as part of multimodal analgesia in patients undergoing hip fracture surgery. The suprainguinal fascia iliaca plane block is a regional block technique that may provide analgesia by affecting nerves related to the lumbar plexus, including the femoral nerve, lateral femoral cutaneous nerve, and obturator nerve. The pericapsular nerve group block and modified techniques, including meta-PENG block, aim to provide analgesia by targeting articular branches involved in hip joint innervation.
This study is designed as a prospective observational single-center study. Adult patients with ASA physical status I-III who are scheduled to undergo hip fracture surgery under spinal anesthesia will be evaluated for eligibility. Patients who provide written informed consent, or whose legal representative provides consent when applicable, will be included.
The regional block technique will be determined according to routine clinical practice and the responsible anesthesiologist's preference. Patients will not be randomized by the study protocol. Patients will be observed in two groups: those receiving ultrasound-guided meta-PENG block and those receiving ultrasound-guided suprainguinal fascia iliaca plane block.
The primary outcome of the study is pain during positioning for spinal anesthesia. Pain will be assessed using the Numeric Rating Scale, where 0 indicates no pain and 10 indicates the worst imaginable pain.
Secondary outcomes will include postoperative Numeric Rating Scale scores at rest and during activity, including back raising and hip flexion; additional analgesic consumption; patient satisfaction assessed using the OR-15 questionnaire; time to mobilization; and length of hospital stay.
Intraoperative data, spinal anesthesia medication dose, regional block and anesthesia methods, postoperative pain scores, additional analgesic requirements, mobilization time, patient satisfaction, and hospitalization duration will be recorded from the hospital information system and anesthesia records.
The study will be conducted at Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital. The study has been reviewed and approved by the institutional scientific research ethics committee.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Meta-PENG Block Group | – | Procedure: Ultrasound-Guided Meta-PENG BlockPatients undergoing hip fracture surgery under spinal anesthesia who receive ultrasound-guided meta-PENG block as part of routine perioperative analgesia management. |
| Suprainguinal Fascia Iliaca Plane Block Group | – | Procedure: Ultrasound-Guided Suprainguinal Fascia Iliaca Plane BlockPatients undergoing hip fracture surgery under spinal anesthesia who receive ultrasound-guided suprainguinal fascia iliaca plane block as part of routine perioperative analgesia management. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adult patients scheduled to undergo hip fracture surgery under spinal anesthesia at Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital will be included. Eligible patients will be ASA physical status I-III and will receive either ultrasound-guided meta-PENG block or ultrasound-guided suprainguinal fascia iliaca plane block as part of routine perioperative analgesia management.
Key inclusion criteria (4 listed)
- Age greater than 18 years
- ASA physical status I-III
- Scheduled to undergo hip fracture surgery under spinal anesthesia
- Written informed consent obtained from the patient or the patient's legal representative
Key exclusion criteria (4 listed)
- Refusal to participate in the study
- ASA physical status IV-V
- Presence of central or autonomic nervous system disease
- Known allergy to the drugs used in the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound-Guided Meta-PENG BlockUltrasound-guided meta-PENG block performed as part of routine perioperative regional analgesia management in patients undergoing hip fracture surgery under spinal anesthesia. | Procedure or surgery | Meta-PENG Block Group |
| Ultrasound-Guided Suprainguinal Fascia Iliaca Plane BlockUltrasound-guided suprainguinal fascia iliaca plane block performed as part of routine perioperative regional analgesia management in patients undergoing hip fracture surgery under spinal anesthesia. | Procedure or surgery | Suprainguinal Fascia Iliaca Plane Block Group |
Primary outcome
Pain During Positioning for Spinal Anesthesia
Time frame: During the positioning for spinal anesthesia, immediately before spinal needle insertion(Periprocedural)
Pain intensity during positioning for spinal anesthesia will be assessed using the Numeric Rating Scale. The Numeric Rating Scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 May 2026.
- Results publication: PubMed 38268183Pai P, Amor D, Lai YH, Echevarria GC. Use and Clinical Relevancy of Pericapsular Nerve Block (PENG) in Total Hip Arthroplasty: A Systematic Review and Meta-analysis. Clin J Pain. 2024 May 1;40(5):320-332. doi: 10.1097/AJP.0000000000001196.
- Results publication: PubMed 30063657Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847.
- Individual participant dataSharing planned: No. Individual participant data will not be shared because the study includes patient clinical data and no data sharing plan was specified in the approved study protocol.
Related trials for Hip Fracture
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Şule Altuncu, MD contact
Sule Altuncu, MD principal investigator
Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Hip Fracture and Postoperative Pain, run by Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 29 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sule Altuncu, MD (+90 216 606 33 00, sule.621@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain During Positioning for Spinal Anesthesia (time frame: During the positioning for spinal anesthesia, immediately before spinal needle insertion(Periprocedural)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07612761, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 May 2026.