Dental EtchingAE SBE BF BBNCT07617480
Comparison of Orthodontic Bracket Bond Failure Using Acid Etching With or Without Sandblasting
A study testing Sandblasting with acid etching vs Acid etching alone and Acid Etching only in people with Dental Etching and Dental Bonding, run by Tanzila Rafique at 1 site in Bangladesh.
Trial summary
The goal of this clinical trial is to assess if sandblasting before acid etching reduce orthodontic bracket bond failure in fixed orthodontic treatment. The main question it aims to answer is: What are the differences in bracket bond failure rate between acid etching with or without sandblasting method for the… Read more about this study
- Who is it for?
- Ages 18 to 64 yearsHealthy volunteers can take part
- Conditions the study is for
- Dental Etching, Dental Bonding, Acid Etching
- What is being tested?
- Sandblasting with acid etching vs Acid etching alone and Acid Etching only
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 15 participants
- Where
- 1 siteBangladesh
- Study dates
- 1 Mar 2026to 1 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 64 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Participants with good general health condition and oral hygiene status.
- Age range of the patients will be 18 years and above.
- Sex of the participants will be both male and female.
- Patients with full permanent dentition present (excluding 3rd molar).
- Patients with enamel integrity, absence of traumatic or carious lesion.
- Participants who had no enamel pretreatment procedure performed with chemical agents.
- Participants with no crossbite, scissor bite or occlusal interference (to prevent any potential early bond failure).
Who cannot join
- Patients who have congenital enamel defects,
- Patients who are in need of orthognathic surgery.
- Patients with craniofacial syndromes.
- Patients who present with partially erupted teeth with hypoplasia.
- Patients for whom a rapid expander or a fixed functional appliance will be planned.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Comparison of Orthodontic Bracket Bond Failure Using Acid Etching With or Without Sandblasting Method for the Preparation of Enamel
The goal of this clinical trial is to assess if sandblasting before acid etching reduce orthodontic bracket bond failure in fixed orthodontic treatment. The main question it aims to answer is:
- What are the differences in bracket bond failure rate between acid etching with or without sandblasting method for the preparation of enamel? Researchers will compare acid etching with sandblasting method to acid etching without sandblasting method for enamel preparation to see if sandblasting prior to acid etching reduce bracket bond failure rate.
Read more
Participants will:
- Receive sandblasting of enamel before acid etching on one side of the mouth and only acid etching on the contralateral side for enamel preparation.
- Participants would visit at the the OPD of Hospital at 3 weeks interval for follow up and for a total duration of 4 months to assess the changes. The number of bracket bond dislodgements at each session will be recorded .
- Being tested
- Sandblasting with acid etching vs Acid etching alone, Acid Etching only
- Keywords
- Acid etching, Sandblasting, Orthodontic bracket, Enamel preparation, Bond failure
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sandblasting with acid etching vs Acid etching aloneProcedure or surgery
Sandblasting will be applied onto the vestibular surfaces of the teeth before applying the etchant;
Acid Etching onlyProcedure or surgery
Acid etching will be applied onto the vestibular surfaces of the teeth for enamel preparation.
| Study group | Role | What they receive |
|---|---|---|
| Sandblasting | Active comparator | Sandblasting will be applied onto the vestibular surfaces of the teeth before applying the etchant Receives: Procedure: Sandblasting with acid etching vs Acid etching alone |
| Acid Etching Alone | Active comparator | Only acid etching will be applied onto the vestibular surfaces of the teeth for enamel preparation. Receives: Procedure: Acid Etching only |
What is being measured
The primary outcome is the main question the study is designed to answer.
To compare the bracket bond failure rate using acid etching with or without sandblasting method for the preparation of enamel.
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jun 2026
- Study start1 Mar 2026
- Primary completion1 Jul 2026
- Study completion1 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dental EtchingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Split mouth design.
- Masking
- None (open label)
- Enrolment
- 15 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tanzila Rafique
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Tanzila Rafique, Bangladesh Medical University
- Investigators
- Mahmood Sajedeen, BDS, FCPS, Study director, Bangladesh Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07617480
- Sponsor's protocol ID
- BMU/2026/1641
- Other IDs
- BMU/2026/1641
- Acronym
- AE SBE BF BB
- Status last verified
- Sep 2026
- First submitted
- 18 May 2026
- Last updated
- 9 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Confidentiality and privacy will be preserved by utilizing unique identifying codes instead of personal identifiers
Study at a glance
From the registry record, last updated by the sponsor on 9 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Orthodontic Bracket Bond Failure Using Acid Etching With or Without Sandblasting Method for the Preparation of Enamel
- ClinicalTrials.gov ID
- NCT07617480
- Acronym / sponsor ID
- AE SBE BF BB / BMU/2026/1641
- Keywords
- Acid etching, Sandblasting, Orthodontic bracket, Enamel preparation, Bond failure
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 15 participants (estimated)
- Lead sponsor
- Tanzila RafiqueUniversity, hospital or other
- Study start
- 1 Mar 2026 (actual)
- Primary completion
- 1 Jul 2026 (actual)
- Study completion
- 1 Sep 2026 (estimated)
- First posted
- 1 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to assess if sandblasting before acid etching reduce orthodontic bracket bond failure in fixed orthodontic treatment. The main question it aims to answer is:
- What are the differences in bracket bond failure rate between acid etching with or without sandblasting method for the preparation of enamel? Researchers will compare acid etching with sandblasting method to acid etching without sandblasting method for enamel preparation to see if sandblasting prior to acid etching reduce bracket bond failure rate.
Participants will:
- Receive sandblasting of enamel before acid etching on one side of the mouth and only acid etching on the contralateral side for enamel preparation.
- Participants would visit at the the OPD of Hospital at 3 weeks interval for follow up and for a total duration of 4 months to assess the changes. The number of bracket bond dislodgements at each session will be recorded .
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Split mouth design.
| Arm | Type | Receives |
|---|---|---|
| Sandblasting | Active comparator | Procedure: Sandblasting with acid etching vs Acid etching aloneSandblasting will be applied onto the vestibular surfaces of the teeth before applying the etchant |
| Acid Etching Alone | Active comparator | Procedure: Acid Etching onlyOnly acid etching will be applied onto the vestibular surfaces of the teeth for enamel preparation. |
Who may qualify
- Ages
- 18 to 64 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Participants with good general health condition and oral hygiene status.
- Age range of the patients will be 18 years and above.
- Sex of the participants will be both male and female.
- Patients with full permanent dentition present (excluding 3rd molar).
- Patients with enamel integrity, absence of traumatic or carious lesion.
Key exclusion criteria (5 listed)
- Patients who have congenital enamel defects,
- Patients who are in need of orthognathic surgery.
- Patients with craniofacial syndromes.
- Patients who present with partially erupted teeth with hypoplasia.
- Patients for whom a rapid expander or a fixed functional appliance will be planned.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Sandblasting with acid etching vs Acid etching aloneSandblasting will be applied onto the vestibular surfaces of the teeth before applying the etchant; | Procedure or surgery | Sandblasting |
| Acid Etching onlyAcid etching will be applied onto the vestibular surfaces of the teeth for enamel preparation. | Procedure or surgery | Acid Etching Alone |
Primary outcome
To compare the bracket bond failure rate using acid etching with or without sandblasting method for the preparation of enamel.
Time frame: 6 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Sep 2026.
- Individual participant dataSharing planned: No. Confidentiality and privacy will be preserved by utilizing unique identifying codes instead of personal identifiers
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mahmood Sajedeen, BDS, FCPS study director
Bangladesh Medical University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Sandblasting with acid etching vs Acid etching alone and Acid Etching only in people with Dental Etching and Dental Bonding, run by Tanzila Rafique at 1 site in Bangladesh.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 9 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Bangladesh. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To compare the bracket bond failure rate using acid etching with or without sandblasting method for the preparation of enamel. (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Sep 2026.