ObesityHBCTNCT07619612
Home-Based Circuit Training in Adults With Obesity
A study testing Home-Based Circuit Training in people with Obesity, run by Chulalongkorn University at 1 site in Thailand.
Trial summary
Obesity is associated with impaired vascular function, metabolic dysfunction, and reduced physical fitness, which increase cardiovascular disease risk. This randomized controlled trial aims to investigate the effects of a 12-week home-based circuit training program using light-to-moderate resistance on vascular… Read more about this study
- Who is it for?
- Ages 19 to 45 years
- Conditions the study is for
- Obesity
- What is being tested?
- Home-Based Circuit Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 29 participants
- Where
- 1 siteThailand
- Study dates
- 18 Jun 2025to 25 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adults with obesity according to the Asia-Pacific criteria (body mass index [BMI] ≥ 27.5 kg/m²).
- Able to participate in a home-based exercise program.
- Willing to provide written informed consent.
Who cannot join
- History of uncontrolled diabetes (HbA1c ≥ 10% or blood glucose ≥ 200 mg/dL).
- Uncontrolled hypertension (≥ 140/90 mmHg).
- Cardiovascular disease.
- Chronic obstructive pulmonary disease.
- Orthopedic conditions limiting exercise participation.
- Participation in regular exercise programs or sports activities within the previous 3 months
Trial locations and contacts
1 site in 1 country.
Thailand1 site
Faculty of Sports Science, Chulalongkorn University
Bangkok, ฺBangkok, 10330
About this study
Official title: Effects of Home-Based Circuit Training on Vascular and Metabolic Health in Adults With Obesity: A Randomized Controlled Trial
Obesity is associated with impaired vascular function, metabolic dysfunction, and reduced physical fitness, which increase cardiovascular disease risk. This randomized controlled trial aims to investigate the effects of a 12-week home-based circuit training program using light-to-moderate resistance on vascular health, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity. Participants will be randomly assigned to either a home-based circuit training group or a control group maintaining usual daily activities. The findings may support the use of home-based exercise as a practical and time-efficient strategy for obesity management and cardiovascular risk reduction.
Read the detailed description
Obesity is a major public health concern associated with endothelial dysfunction, arterial stiffness, metabolic impairment, and reduced physical fitness. Although exercise training is recommended for obesity management, adherence to supervised exercise programs may be limited by time constraints and accessibility. Home-based circuit training may provide a feasible alternative that combines aerobic and resistance exercise within a time-efficient format.
This randomized controlled trial investigates the effects of a 12-week home-based circuit training intervention on vascular function, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity.
Participants with obesity (BMI ≥ 27.5 kg/m²) will be randomly assigned to either a circuit training group or a control group. The intervention group will perform home-based circuit training using light-to-moderate resistance three times weekly for 12 weeks, while the control group will maintain usual activities.
Primary vascular outcomes include flow-mediated dilation, carotid intima-media thickness, brachial-ankle pulse wave velocity, and post-occlusive reactive hyperemia. Secondary outcomes include body composition, fasting plasma glucose, resting metabolic rate, substrate oxidation, physical activity, muscular strength, flexibility, and cardiorespiratory fitness.
The study aims to determine whether home-based circuit training can improve vascular and metabolic health and serve as a practical strategy for reducing cardiovascular risk in adults with obesity.
- Conditions
- Obesity
- Being tested
- Home-Based Circuit Training
- Keywords
- : circuit training, vascular function, cardiometabolic, physical fitness, obesity
- Medical subject headings
- Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Home-Based Circuit TrainingBehavioural
Participants will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit-based exercises targeting major muscle groups, and cool-down activities. The intervention is designed to improve vascular and metabolic health in adults with obesity.
The training program consisted of two phases: phase 1 (weeks 1-6) and phase 2 (weeks 7-12).
During phase 1, participants performed resistance exercises at an intensity of 65-70% of one-repetition maximum (1RM). Each exercise consisted of 12 repetitions, with a 1-minute rest between exercises. The lifting tempo was maintained at 2:2 (concentric: eccentric). Participants completed 8 exercises per circuit for a total of 3 circuits, with a 2-minute rest between circuits.
During phase 2, the intensity was increased to 70-75% of 1RM, while maintaining 12 repetitions per exercise. The rest interval between exercises was reduced to 30 seconds, with the same lifting tempo (2:2). Participants complete
| Study group | Role | What they receive |
|---|---|---|
| Home-Based Circuit Training | Experimental | Participants in this group will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit exercise, and cool-down components designed to improve vascular and metabolic health. Receives: Behavioral: Home-Based Circuit Training |
| Control Group | No intervention | participants in the control group will maintain their usual daily activities without participating in the exercise intervention during the study period. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Vascular Function
Change in flow-mediated dilation from baseline to 12 weeks.
Measured: Baseline and 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Jun 2026
- Study start18 Jun 2025
- Primary completion31 Aug 2025
- Study completion25 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ObesityStudies of the same condition, open and under way.
- More trials run by Chulalongkorn UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to either a home-based circuit training group or a control group in a parallel-group design.
- Masking
- None (open label)
- Enrolment
- 29 participants (actual)
Sponsor and investigators
- Lead sponsor
- Chulalongkorn University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Daroonwan Suksom, PhD, Study director, Faculty of Sports Science, Chulalongkorn University, Bangkok, ThailandTunyakarn Worasettawat, PhD, Principal investigator, Faculty of Sports Science, Chulalongkorn University, Bangkok, ThailandHirofumi Tanaka, PhD, Study chair, Department of Kinesiology and Health Education, The University of Texas at Austin, USA
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07619612
- Sponsor's protocol ID
- HBCT-OB-2026
- Other IDs
- Ratchadapisek Postdoctoral
- Acronym
- HBCT
- Status last verified
- May 2026
- First submitted
- 26 May 2026
- Last updated
- 2 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) may be shared upon reasonable request after publication of the study results and approval by the principal investigator.
Study at a glance
From the registry record, last updated by the sponsor on 2 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Home-Based Circuit Training on Vascular and Metabolic Health in Adults With Obesity: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07619612
- Acronym / sponsor ID
- HBCT / HBCT-OB-2026
- Conditions
- Obesity
- Keywords
- : circuit training, vascular function, cardiometabolic, physical fitness, obesity
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 29 participants (actual)
- Lead sponsor
- Chulalongkorn UniversityUniversity, hospital or other
- Study start
- 18 Jun 2025 (actual)
- Primary completion
- 31 Aug 2025 (actual)
- Study completion
- 25 Dec 2025 (actual)
- First posted
- 2 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Obesity is associated with impaired vascular function, metabolic dysfunction, and reduced physical fitness, which increase cardiovascular disease risk. This randomized controlled trial aims to investigate the effects of a 12-week home-based circuit training program using light-to-moderate resistance on vascular health, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity. Participants will be randomly assigned to either a home-based circuit training group or a control group maintaining usual daily activities. The findings may support the use of home-based exercise as a practical and time-efficient strategy for obesity management and cardiovascular risk reduction.
Detailed description
Obesity is a major public health concern associated with endothelial dysfunction, arterial stiffness, metabolic impairment, and reduced physical fitness. Although exercise training is recommended for obesity management, adherence to supervised exercise programs may be limited by time constraints and accessibility. Home-based circuit training may provide a feasible alternative that combines aerobic and resistance exercise within a time-efficient format.
This randomized controlled trial investigates the effects of a 12-week home-based circuit training intervention on vascular function, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity.
Participants with obesity (BMI ≥ 27.5 kg/m²) will be randomly assigned to either a circuit training group or a control group. The intervention group will perform home-based circuit training using light-to-moderate resistance three times weekly for 12 weeks, while the control group will maintain usual activities.
Primary vascular outcomes include flow-mediated dilation, carotid intima-media thickness, brachial-ankle pulse wave velocity, and post-occlusive reactive hyperemia. Secondary outcomes include body composition, fasting plasma glucose, resting metabolic rate, substrate oxidation, physical activity, muscular strength, flexibility, and cardiorespiratory fitness.
The study aims to determine whether home-based circuit training can improve vascular and metabolic health and serve as a practical strategy for reducing cardiovascular risk in adults with obesity.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to either a home-based circuit training group or a control group in a parallel-group design.
| Arm | Type | Receives |
|---|---|---|
| Home-Based Circuit Training | Experimental | Behavioral: Home-Based Circuit TrainingParticipants in this group will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit exercise, and cool-down components designed to improve vascular and metabolic health. |
| Control Group | No intervention | –participants in the control group will maintain their usual daily activities without participating in the exercise intervention during the study period. |
Who may qualify
- Ages
- 19 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Adults with obesity according to the Asia-Pacific criteria (body mass index [BMI] ≥ 27.5 kg/m²).
- Able to participate in a home-based exercise program.
- Willing to provide written informed consent.
Key exclusion criteria (6 listed)
- History of uncontrolled diabetes (HbA1c ≥ 10% or blood glucose ≥ 200 mg/dL).
- Uncontrolled hypertension (≥ 140/90 mmHg).
- Cardiovascular disease.
- Chronic obstructive pulmonary disease.
- Orthopedic conditions limiting exercise participation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Home-Based Circuit TrainingParticipants will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit-based exercises targeting major muscle groups, and cool-down activities. The intervention is designed to improve vascular and metabolic health in adults with obesity. The training program consisted of two phases: phase 1 (weeks 1-6) and phase 2 (weeks 7-12). During phase 1, participants performed resistance exercises at an intensity of 65-70% of one-repetition maximum (1RM). Each exercise consisted of 12 repetitions, with a 1-minute rest between exercises. The lifting tempo was maintained at 2:2 (concentric: eccentric). Participants completed 8 exercises per circuit for a total of 3 circuits, with a 2-minute rest between circuits. During phase 2, the intensity was increased to 70-75% of 1RM, while maintaining 12 repetitions per exercise. The rest interval between exercises was reduced to 30 seconds, with the same lifting tempo (2:2). Participants complete | Behavioural | Home-Based Circuit Training |
Primary outcome
Vascular Function
Time frame: Baseline and 12 weeks
Change in flow-mediated dilation from baseline to 12 weeks.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Jun 2026.
- Individual participant dataSharing planned: No. Individual participant data (IPD) may be shared upon reasonable request after publication of the study results and approval by the principal investigator.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Daroonwan Suksom, PhD study director
Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand
Tunyakarn Worasettawat, PhD principal investigator
Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand
Hirofumi Tanaka, PhD study chair
Department of Kinesiology and Health Education, The University of Texas at Austin, USA
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Home-Based Circuit Training in people with Obesity, run by Chulalongkorn University at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Vascular Function (time frame: Baseline and 12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jun 2026.