RetentionNCT07622277
Comparative 3-dimensional Superimposition Analysis of Dentition in Horizontal and Vertical Grower During the Retention Phase -A Prospective Clinical Trial''
A study testing 3 planes of space in people with Retention and Relapse, run by Postgraduate Institute of Dental Sciences Rohtak at 1 site in India.
Trial summary
This study aims to investigate the relationship between facial type and relapse of dentition post-orthodontically during the retention phase. According to the retention theorem "teeth which have been moved through orthodontic treatment tend to naturally return to their original position. Read more about this study
- Who is it for?
- Ages 18 to 45 yearsHealthy volunteers can take part
- What is being tested?
- 3 planes of space
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 44 participants
- Where
- 1 siteIndia
- Study dates
- 4 Feb 2025to Jul 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Fixed orthodontic cases with FMA of 26 0 or more for hyperdivergent cases and FMA Of 24 o or less for hypodivergent cases.
- Optimal functional occlusion at end of treatment (PAR score >70%).
- Littles irregularity index (Pre-treatment <6mm in both upper and lower arch).
- Nonsurgical and non-orthopedic patients and non syndromic patients.
- Optimal periodontal condition and Good oral hygiene (probing depth <3mm, gingival index score <1
- Good compliance regarding retainer wear
Who cannot join
- Subjects with incomplete orthodontic treatment.
- TMJ disorder patients.
- Any systemic disease affecting bone and general growth.
- Patients with incomplete records
- Patient who fail to follow up or undergo complete treatment.
- Patient with learning difficulties
- Patients having antibiotic therapy within previous 3 months and used anti inflammatory drugs in the month before the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
India1 site, 1 recruiting
- Recruiting
Dr.Manisha
Rohtak, Haryana, 124001
Manpreet Kaur, BDS, 07901751776, manpreetkaur18u@gmail.com
About this study
This study aims to investigate the relationship between facial type and relapse of dentition post-orthodontically during the retention phase. According to the retention theorem "teeth which have been moved through orthodontic treatment tend to naturally return to their original position. It is hypothesized that significant differences will exist in tooth movement patterns between horizontal and vertical growers, with horizontal growers exhibiting more pronounced tooth movement in the vertical plane particularly in the overbite as compared to the vertical growers . Furthermore, it is expected that facial type will influence the stability of orthodontic treatment outcomes, with long-faced individuals showing more relapse of mandibular incisor alignment and crowding. By exploring this relationship, this study aims to provide valuable insights into the factors influencing orthodontic treatment outcomes and stability. With long-faced individuals exhibiting more mandibular backward rotation and short-faced individuals showing forward rotation, which increases the risk of deep bite . Additionally, understanding these factors is crucial for orthodontists to predict and prevent potential relapse, ensuring optimal treatment results and long-term stability. Hence, the present trial will be undertaken to assess the changes and compare If there is any difference in tooth movement in 3-Dimensional superimposition in the dentition in horizontal and vertical growers post orthodontically over a period of retention phase.
Read the detailed description
Orthodontic treatment is involved with the correction of irregular dental positions and skeletal structures. It is a specialized dental discipline that involves the application of biomechanical principles to correct dentofacial anomalies, thereby enhancing the morphological and functional harmony of the stomatognathic system. However, achieving stable results at the end of active treatment remains a significant challenge, as teeth and their supporting structures tend to revert to their original malocclusion following orthodontic and orthopedic changes. Such changes are attributed to either the tissue's " physiologic rebound " or normal development. The growth changes that take place after treatment can result in relapse of the occlusion and of the tooth alignment. Late growth changes in the jaws have been implicated as a factor contributing to post-treatment relapse, with some suggesting that disharmonious growth after treatment may compromise occlusal stability.
The cause of postorthodontic dental changes remains uncertain, although it appears to involve a combination of dental relapse and continued growth. Despite this uncertainty, research has shown that several variables studied remained stable after treatment. However, for those variables that did exhibit change, the majority seemed to be related primarily to growth alone or to a combination of growth and dental relapse. Furthermore, alterations attributed to growth consisted of variables that were directly or indirectly affected by continued craniofacial maturation, highlighting the significant role that growth plays in postorthodontic dental changes.
Natural growth and development continue throughout life, influencing the position and alignment of teeth. Understanding the interplay between orthodontic treatment, relapse, and natural growth is crucial for optimizing treatment outcomes and retention protocols.
Individuals can be broadly classified into two categories based on their growth patterns: horizontal growers and vertical growers.
Horizontal growers exhibit a more pronounced increase in mandibular length, whereas vertical growers display a greater increase in mandibular height. These distinct growth patterns can significantly influence orthodontic treatment outcomes and relapse tendencies.
Research suggests that growth and relapse contribute to post-treatment changes, with facial morphology and mandibular rotation influencing occlusal stability.
The study (2020) sheds light on the changes that occur in the lower incisors after orthodontic treatment, tooth movement by using a TDI (Tooth Displacement Index) where each single tooth is registered at the different follow-up. The study found that approximately 25% of the tooth movements observed at 6 years (T2) and 12 years (T3) after treatment were not present before treatment (T0). This suggests that these changes were due to natural growth rather than relapse from orthodontic treatment.
Several studies have demonstrated that facial morphology influences post-treatment changes. These changes in vertical parameters of growing individuals can be influenced by mandibular rotation accompanying growth and orthodontic treatment. Research suggests that different facial types with long-faced individuals demonstrate more mandibular backward rotation compared to those with shorter faces.
Researcher noted that forward rotation of the mandible, characteristic of short facial types, influences tooth eruption patterns and can increase the risk of deep bite and mandibular incisor crowding in extreme cases and individual variations in the direction of condylar growth during adolescence can be quite significant, ranging up to 45 degrees. This variability underscores the complex interplay between facial growth patterns and anterior occlusion, resulting in significant individual differences in the development of the mandibular dentoalveolar structure. This variability is aptly demonstrated by study (1963) on mandibular growth. Subjects with an upward and forward growing condyle (Figure A), exhibit pronounced mesial migration of the lower dentition, accompanied by limited forward movement of the incisors. In contrast, the second subject (Figure B) displays a more average vertical eruption pattern of the posterior teeth, with some degree of mesial migration and limited forward movement of the anterior teeth. The third subject, with a posterior condylar growth direction (Figure C), demonstrates vertical eruption of the posterior teeth with no mesial movement, and the incisors erupt vertically and posteriorly. Notably, the occlusal characteristics of these subjects differ significantly. The patient in Figure A presents with a deep bite, whereas the patient in Figure C exhibits a severe anterior open bite.
Bishara and Little also shed light on the long-term stability of orthodontic treatment. Bishara's study revealed that overbite relapse occurs more frequently than overjet relapse, and that the maxillary intercanine width is more stable than its mandibular counterpart. Little's investigation of 65 patients found significant individual variation in long-term treatment outcomes. Notably, all patients experienced a decrease in arch width and length over time, with two-thirds developing lower arch crowding after retention. These findings suggest that maintaining lower arch alignment is challenging, with success rates below 30%.
Research by Roberta A. Gardner's longitudinal study . The research reveals that the mandibular arch, particularly the lower incisors, undergo significant changes over time. Notably, relapse of mandibular incisor alignment and crowding is a common phenomenon, while inter-canine width tends to decrease. Additionally, some patients experience an increase in overbite. The study highlights that patients with initial severe crowding or irregularities are more prone to these changes.
A three-dimensional superimposition study conducted to assess these post-treatment tooth movement in the dentition. Utilizing advanced 3D superimposition techniques, researchers evaluated tooth movement patterns after orthodontic treatment. The results revealed significant displacements in the transverse and vertical dimensions, highlighting the complexity of tooth movement. By employing 3D superimposition, the study provided detailed insights into tooth movement patterns, underscoring the importance of precise retention strategies to maintain optimal treatment outcomes.
Hence, the present trial will be undertaken to assess the changes and compare If there is any difference in tooth movement in 3-Dimensional superimposition in the dentition in horizontal and vertical growers post orthodontically over a period of retention phase.
- Being tested
- 3 planes of space
- Medical subject headings
- Recurrence
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
3 planes of spaceOther
To evaluate and compare the changes in dentition in 3 planes of space • Antero-posterior plane (Y-axis) • Vertical plane (Z-axis) • Transverse plane (X-axis)
| Study group | Role | What they receive |
|---|---|---|
| vertical grower | Other | Patients belonging to group 1 will be patient with vertical growth pattern who have undergone fixed orthodontic cases and are ready for debonding with FMA of 26 0 or more. Begg's Retainer will be formed by conventional method and delivered within 24 hours of debonding.
To compare 3 dimensional dentitional changes post orthodontically treated patients with vertical growth pattern over a 12 month retention period. Receives: Other: 3 planes of space |
| Horizontal grower | Other | Patients belonging to group 2 will be patient with horizontal growth pattern who have undergone Fixed orthodontic cases and are ready for debonding with with FMA Of 24 o or less. Begg's Retainer will be formed by conventional method and delivered within 24 hours of debonding.
To compare 3 dimensional dentitional changes post orthodontically treated patients with horizontal growth pattern over a 12 month retention period. Receives: Other: 3 planes of space |
What is being measured
The primary outcome is the main question the study is designed to answer.
To compare 3 dimensional dentitional changes in dentition in 3 planes of space
To compare 3 dimensional dentitional changes in dentition in 3 planes of space using superimposition software • Antero-posterior plane (Y-axis) • Vertical plane (Z-axis) • Transverse plane (X-axis) at, T0(at the time of retainer delivery), T1(1 month of retainer delivery), T2(3 months of retainer delivery) and T3 (6 months of retainer delivery) ,T4 (12 months of retainer delivery) time interval.
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jun 2026
- Study start4 Feb 2025
- Primary completionDec 2026 (estimated)
- Study completionJul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for RetentionStudies of the same condition, open and under way.
- More trials run by Postgraduate Institute of Dental Sciences RohtakThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 44 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Postgraduate Institute of Dental Sciences Rohtak
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Dr manisha Kamal kukreja, MDS, Study director, PGIDS Rohtak
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07622277
- Sponsor's protocol ID
- Dr. Manpreet Kaur
- Status last verified
- May 2026
- First submitted
- 1 Jan 2026
- Last updated
- 3 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative 3-dimensional Superimposition Analysis of Dentition in Horizontal and Vertical Grower During the Retention Phase -A Prospective Clinical Trial''
- ClinicalTrials.gov ID
- NCT07622277
- Acronym / sponsor ID
- Dr. Manpreet Kaur
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 44 participants (estimated)
- Lead sponsor
- Postgraduate Institute of Dental Sciences RohtakUniversity, hospital or other
- Study start
- 4 Feb 2025 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Jul 2027 (estimated)
- First posted
- 3 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to investigate the relationship between facial type and relapse of dentition post-orthodontically during the retention phase. According to the retention theorem "teeth which have been moved through orthodontic treatment tend to naturally return to their original position. It is hypothesized that significant differences will exist in tooth movement patterns between horizontal and vertical growers, with horizontal growers exhibiting more pronounced tooth movement in the vertical plane particularly in the overbite as compared to the vertical growers . Furthermore, it is expected that facial type will influence the stability of orthodontic treatment outcomes, with long-faced individuals showing more relapse of mandibular incisor alignment and crowding. By exploring this relationship, this study aims to provide valuable insights into the factors influencing orthodontic treatment outcomes and stability. With long-faced individuals exhibiting more mandibular backward rotation and short-faced individuals showing forward rotation, which increases the risk of deep bite . Additionally, understanding these factors is crucial for orthodontists to predict and prevent potential relapse, ensuring optimal treatment results and long-term stability. Hence, the present trial will be undertaken to assess the changes and compare If there is any difference in tooth movement in 3-Dimensional superimposition in the dentition in horizontal and vertical growers post orthodontically over a period of retention phase.
Detailed description
Orthodontic treatment is involved with the correction of irregular dental positions and skeletal structures. It is a specialized dental discipline that involves the application of biomechanical principles to correct dentofacial anomalies, thereby enhancing the morphological and functional harmony of the stomatognathic system. However, achieving stable results at the end of active treatment remains a significant challenge, as teeth and their supporting structures tend to revert to their original malocclusion following orthodontic and orthopedic changes. Such changes are attributed to either the tissue's " physiologic rebound " or normal development. The growth changes that take place after treatment can result in relapse of the occlusion and of the tooth alignment. Late growth changes in the jaws have been implicated as a factor contributing to post-treatment relapse, with some suggesting that disharmonious growth after treatment may compromise occlusal stability.
The cause of postorthodontic dental changes remains uncertain, although it appears to involve a combination of dental relapse and continued growth. Despite this uncertainty, research has shown that several variables studied remained stable after treatment. However, for those variables that did exhibit change, the majority seemed to be related primarily to growth alone or to a combination of growth and dental relapse. Furthermore, alterations attributed to growth consisted of variables that were directly or indirectly affected by continued craniofacial maturation, highlighting the significant role that growth plays in postorthodontic dental changes.
Natural growth and development continue throughout life, influencing the position and alignment of teeth. Understanding the interplay between orthodontic treatment, relapse, and natural growth is crucial for optimizing treatment outcomes and retention protocols.
Individuals can be broadly classified into two categories based on their growth patterns: horizontal growers and vertical growers.
Horizontal growers exhibit a more pronounced increase in mandibular length, whereas vertical growers display a greater increase in mandibular height. These distinct growth patterns can significantly influence orthodontic treatment outcomes and relapse tendencies.
Research suggests that growth and relapse contribute to post-treatment changes, with facial morphology and mandibular rotation influencing occlusal stability.
The study (2020) sheds light on the changes that occur in the lower incisors after orthodontic treatment, tooth movement by using a TDI (Tooth Displacement Index) where each single tooth is registered at the different follow-up. The study found that approximately 25% of the tooth movements observed at 6 years (T2) and 12 years (T3) after treatment were not present before treatment (T0). This suggests that these changes were due to natural growth rather than relapse from orthodontic treatment.
Several studies have demonstrated that facial morphology influences post-treatment changes. These changes in vertical parameters of growing individuals can be influenced by mandibular rotation accompanying growth and orthodontic treatment. Research suggests that different facial types with long-faced individuals demonstrate more mandibular backward rotation compared to those with shorter faces.
Researcher noted that forward rotation of the mandible, characteristic of short facial types, influences tooth eruption patterns and can increase the risk of deep bite and mandibular incisor crowding in extreme cases and individual variations in the direction of condylar growth during adolescence can be quite significant, ranging up to 45 degrees. This variability underscores the complex interplay between facial growth patterns and anterior occlusion, resulting in significant individual differences in the development of the mandibular dentoalveolar structure. This variability is aptly demonstrated by study (1963) on mandibular growth. Subjects with an upward and forward growing condyle (Figure A), exhibit pronounced mesial migration of the lower dentition, accompanied by limited forward movement of the incisors. In contrast, the second subject (Figure B) displays a more average vertical eruption pattern of the posterior teeth, with some degree of mesial migration and limited forward movement of the anterior teeth. The third subject, with a posterior condylar growth direction (Figure C), demonstrates vertical eruption of the posterior teeth with no mesial movement, and the incisors erupt vertically and posteriorly. Notably, the occlusal characteristics of these subjects differ significantly. The patient in Figure A presents with a deep bite, whereas the patient in Figure C exhibits a severe anterior open bite.
Bishara and Little also shed light on the long-term stability of orthodontic treatment. Bishara's study revealed that overbite relapse occurs more frequently than overjet relapse, and that the maxillary intercanine width is more stable than its mandibular counterpart. Little's investigation of 65 patients found significant individual variation in long-term treatment outcomes. Notably, all patients experienced a decrease in arch width and length over time, with two-thirds developing lower arch crowding after retention. These findings suggest that maintaining lower arch alignment is challenging, with success rates below 30%.
Research by Roberta A. Gardner's longitudinal study . The research reveals that the mandibular arch, particularly the lower incisors, undergo significant changes over time. Notably, relapse of mandibular incisor alignment and crowding is a common phenomenon, while inter-canine width tends to decrease. Additionally, some patients experience an increase in overbite. The study highlights that patients with initial severe crowding or irregularities are more prone to these changes.
A three-dimensional superimposition study conducted to assess these post-treatment tooth movement in the dentition. Utilizing advanced 3D superimposition techniques, researchers evaluated tooth movement patterns after orthodontic treatment. The results revealed significant displacements in the transverse and vertical dimensions, highlighting the complexity of tooth movement. By employing 3D superimposition, the study provided detailed insights into tooth movement patterns, underscoring the importance of precise retention strategies to maintain optimal treatment outcomes.
Hence, the present trial will be undertaken to assess the changes and compare If there is any difference in tooth movement in 3-Dimensional superimposition in the dentition in horizontal and vertical growers post orthodontically over a period of retention phase.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| vertical grower | Other | Other: 3 planes of spacePatients belonging to group 1 will be patient with vertical growth pattern who have undergone fixed orthodontic cases and are ready for debonding with FMA of 26 0 or more. Begg's Retainer will be formed by conventional method and delivered within 24 hours of debonding. To compare 3 dimensional dentitional changes post orthodontically treated patients with vertical growth pattern over a 12 month retention period. |
| Horizontal grower | Other | Other: 3 planes of spacePatients belonging to group 2 will be patient with horizontal growth pattern who have undergone Fixed orthodontic cases and are ready for debonding with with FMA Of 24 o or less. Begg's Retainer will be formed by conventional method and delivered within 24 hours of debonding. To compare 3 dimensional dentitional changes post orthodontically treated patients with horizontal growth pattern over a 12 month retention period. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Fixed orthodontic cases with FMA of 26 0 or more for hyperdivergent cases and FMA Of 24 o or less for hypodivergent cases.
- Optimal functional occlusion at end of treatment (PAR score >70%).
- Littles irregularity index (Pre-treatment <6mm in both upper and lower arch).
- Nonsurgical and non-orthopedic patients and non syndromic patients.
- Optimal periodontal condition and Good oral hygiene (probing depth <3mm, gingival index score <1
Key exclusion criteria (7 listed)
- Subjects with incomplete orthodontic treatment.
- TMJ disorder patients.
- Any systemic disease affecting bone and general growth.
- Patients with incomplete records
- Patient who fail to follow up or undergo complete treatment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 3 planes of spaceTo evaluate and compare the changes in dentition in 3 planes of space • Antero-posterior plane (Y-axis) • Vertical plane (Z-axis) • Transverse plane (X-axis) | Other | Horizontal grower, vertical grower |
Primary outcome
To compare 3 dimensional dentitional changes in dentition in 3 planes of space
Time frame: 12 months
To compare 3 dimensional dentitional changes in dentition in 3 planes of space using superimposition software • Antero-posterior plane (Y-axis) • Vertical plane (Z-axis) • Transverse plane (X-axis) at, T0(at the time of retainer delivery), T1(1 month of retainer delivery), T2(3 months of retainer delivery) and T3 (6 months of retainer delivery) ,T4 (12 months of retainer delivery) time interval.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Dr manisha Kamal kukreja, MDS study director
PGIDS Rohtak
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing 3 planes of space in people with Retention and Relapse, run by Postgraduate Institute of Dental Sciences Rohtak at 1 site in India.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 3 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in India. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Dr Manisha kamal kukreja, MDS (9215650617, mk3pgids@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To compare 3 dimensional dentitional changes in dentition in 3 planes of space (time frame: 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Jun 2026.