Elite Male Sailing AthletesNCT07625696
Study on the Effect of Hyperbaric Oxygen Intervention on Relieving Sports Fatigue of Sailors
A study testing Mild Hyperbaric Oxygen Therapy in people with Elite Male Sailing Athletes, run by Shanghai Research Institute of Sports Science.
Trial summary
1. Research Purpose Intensive training often causes autonomic nerve imbalance, poor microcirculation and slow fatigue recovery in elite sailing athletes. This study adopted 1.3 ATA mild hyperbaric oxygen with 28% oxygen concentration for a 6-week intervention. Read more about this study
- Who is it for?
- Ages 18 to 35 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Elite Male Sailing Athletes
- What is being tested?
- Mild Hyperbaric Oxygen Therapy
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 16 participants
- Where
- No sites listed yet
- Study dates
- 30 Jun 2026to 29 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Male elite sailing athletes aged 18-35 years
- Holding a national first-class athlete certificate or above
- With at least 5 years of professional sailing training experience
- Engaging in regular sailing training ≥ 5 times per week
- Voluntarily sign the informed consent form
Who cannot join
- - Presence of cardiovascular, respiratory, or neurological diseases
- Absolute contraindications to hyperbaric oxygen therapy
- Current injury or illness requiring medical treatment or training suspension
- Use of any medications or supplements that may affect fatigue recovery or autonomic function
- Participation in other concurrent recovery interventions during the study
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
- Research Purpose Intensive training often causes autonomic nerve imbalance, poor microcirculation and slow fatigue recovery in elite sailing athletes. This study adopted 1.3 ATA mild hyperbaric oxygen with 28% oxygen concentration for a 6-week intervention. It aimed to explore whether mild hyperbaric oxygen can improve athletes' autonomic nerve function, microcirculation and fatigue-related biochemical indicators. Meanwhile, it intended to estimate the effect size, provide basis for future large-scale formal trials, and optimize fatigue recovery strategies for sailing athletes and other endurance athletes.
- Study Population A total of 16 elite male sailing athletes were enrolled and randomly divided into two groups with 8 participants in each group. Inclusion criteria: aged over 18 years; holding national first-class athlete certificate or above; participating in systematic sailing training at least 5 times a week with more than 5 years of professional training experience. Those with cardiovascular diseases, absolute contraindications to hyperbaric oxygen, training suspension due to injury and other ineligible conditions were excluded.
- Primary Outcome Measures Autonomic nerve function: Heart rate variability (HRV) indicators were tested to observe whether hyperbaric oxygen balances sympathetic and parasympathetic nerves and relieves training-induced autonomic disorder.
Microcirculation function: Measured muscle microcirculation blood flow velocity, capillary perfusion and thermal stimulation microvascular reserve capacity to evaluate the improvement of peripheral blood circulation.
Read more
Fatigue and biochemical biomarkers:
Routine blood indexes: red blood cell, hemoglobin, white blood cell; Exercise injury and metabolic indexes: creatine kinase (CK), blood urea nitrogen (BUN), testosterone and cortisol; Oxidative stress indexes: malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), to assess the body's oxidation-antioxidant status, inflammation level and fatigue recovery degree.
- Conditions
- Elite Male Sailing Athletes
- Being tested
- Mild Hyperbaric Oxygen Therapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mild Hyperbaric Oxygen TherapyDevice
Participants receive mild hyperbaric oxygen therapy (mHBOT) in a hyperbaric chamber at 1.3 atmospheres absolute (ATA) with 28% oxygen concentration, for 60 minutes per session, 5 sessions per week over 6 weeks. All participants continue their standard sailing training regimen throughout the study.
| Study group | Role | What they receive |
|---|---|---|
| Mild Hyperbaric Oxygen Intervention Group | Experimental | Not described Receives: Device: Mild Hyperbaric Oxygen Therapy |
| Control Group (No Hyperbaric Oxygen) | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Heart Rate Variability (HRV)
Measured: Baseline (Week 0), Post-intervention (Week 6)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Jun 2026
- Study start30 Jun 2026 (estimated)
- Primary completion30 Sep 2026 (estimated)
- Study completion29 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Elite Male Sailing AthletesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 16 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Shanghai Research Institute of Sports Science
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07625696
- Sponsor's protocol ID
- LLSC20250004
- Status last verified
- Jul 2026
- First submitted
- 29 May 2026
- Last updated
- 30 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared publicly. The study subjects are competitive athletes. Disclosure of individual-level data involves athletes' personal privacy and confidential training information, which cannot be released externally.
Study at a glance
From the registry record, last updated by the sponsor on 30 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Study on the Effect of Hyperbaric Oxygen Intervention on Relieving Sports Fatigue of Sailors
- ClinicalTrials.gov ID
- NCT07625696
- Acronym / sponsor ID
- LLSC20250004
- Conditions
- Elite Male Sailing Athletes
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 16 participants (estimated)
- Lead sponsor
- Shanghai Research Institute of Sports ScienceUniversity, hospital or other
- Study start
- 30 Jun 2026 (estimated)
- Primary completion
- 30 Sep 2026 (estimated)
- Study completion
- 29 Oct 2026 (estimated)
- First posted
- 4 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
- Research Purpose Intensive training often causes autonomic nerve imbalance, poor microcirculation and slow fatigue recovery in elite sailing athletes. This study adopted 1.3 ATA mild hyperbaric oxygen with 28% oxygen concentration for a 6-week intervention. It aimed to explore whether mild hyperbaric oxygen can improve athletes' autonomic nerve function, microcirculation and fatigue-related biochemical indicators. Meanwhile, it intended to estimate the effect size, provide basis for future large-scale formal trials, and optimize fatigue recovery strategies for sailing athletes and other endurance athletes.
- Study Population A total of 16 elite male sailing athletes were enrolled and randomly divided into two groups with 8 participants in each group. Inclusion criteria: aged over 18 years; holding national first-class athlete certificate or above; participating in systematic sailing training at least 5 times a week with more than 5 years of professional training experience. Those with cardiovascular diseases, absolute contraindications to hyperbaric oxygen, training suspension due to injury and other ineligible conditions were excluded.
- Primary Outcome Measures Autonomic nerve function: Heart rate variability (HRV) indicators were tested to observe whether hyperbaric oxygen balances sympathetic and parasympathetic nerves and relieves training-induced autonomic disorder.
Microcirculation function: Measured muscle microcirculation blood flow velocity, capillary perfusion and thermal stimulation microvascular reserve capacity to evaluate the improvement of peripheral blood circulation.
Fatigue and biochemical biomarkers:
Routine blood indexes: red blood cell, hemoglobin, white blood cell; Exercise injury and metabolic indexes: creatine kinase (CK), blood urea nitrogen (BUN), testosterone and cortisol; Oxidative stress indexes: malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), to assess the body's oxidation-antioxidant status, inflammation level and fatigue recovery degree.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Mild Hyperbaric Oxygen Intervention Group | Experimental | Device: Mild Hyperbaric Oxygen Therapy |
| Control Group (No Hyperbaric Oxygen) | No intervention | – |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Male elite sailing athletes aged 18-35 years
- Holding a national first-class athlete certificate or above
- With at least 5 years of professional sailing training experience
- Engaging in regular sailing training ≥ 5 times per week
- Voluntarily sign the informed consent form
Key exclusion criteria (5 listed)
- - Presence of cardiovascular, respiratory, or neurological diseases
- Absolute contraindications to hyperbaric oxygen therapy
- Current injury or illness requiring medical treatment or training suspension
- Use of any medications or supplements that may affect fatigue recovery or autonomic function
- Participation in other concurrent recovery interventions during the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mild Hyperbaric Oxygen TherapyParticipants receive mild hyperbaric oxygen therapy (mHBOT) in a hyperbaric chamber at 1.3 atmospheres absolute (ATA) with 28% oxygen concentration, for 60 minutes per session, 5 sessions per week over 6 weeks. All participants continue their standard sailing training regimen throughout the study. | Device | Mild Hyperbaric Oxygen Intervention Group |
Primary outcome
Change in Heart Rate Variability (HRV)
Time frame: Baseline (Week 0), Post-intervention (Week 6)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Jul 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared publicly. The study subjects are competitive athletes. Disclosure of individual-level data involves athletes' personal privacy and confidential training information, which cannot be released externally.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Mild Hyperbaric Oxygen Therapy in people with Elite Male Sailing Athletes, run by Shanghai Research Institute of Sports Science.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 30 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact jin yu (+86 18101732823, 759559257@qq.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Heart Rate Variability (HRV) (time frame: Baseline (Week 0), Post-intervention (Week 6)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Jul 2026.