Chronic Kidney DiseasesinterventionNCT07628621
Exercise On Bone Metabolism Markers In Chronic Kidney Disease
A study testing resisted exercise training on some resistance machines and treadmill exercise training in people with Chronic Kidney Diseases, run by Badr University at 1 site in Egypt.
Trial summary
Sixty chronic kidney disease patients, Measurement of bone turnover markers done prior to the study and at the end of the study after 6 months. Read more about this study
- Who is it for?
- Ages 30 to 50 years
- Conditions the study is for
- Chronic Kidney Diseases
- What is being tested?
- resisted exercise training on some resistance machines and treadmill exercise training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Dec 2025to 30 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Non-smokers,
- no alcohol consumption
- no intake of hormone replacement therapy
- mass index ranged from 20-24 kg/m2.
Who cannot join
- diabetes disorders
- hypertension disorders
- cardiac disorders
- musculoskeletal disorders
- endocrine disorders
- intake of medications that may affect bone metabolism.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Aerobic Versus Resistance Exercise On Bone Metabolism Markers In Chronic Kidney Disease
Sixty chronic kidney disease patients, Measurement of bone turnover markers done prior to the study and at the end of the study after 6 months.
Read the detailed description
Sixty chronic kidney disease patients, Measurement of bone turnover markers done prior to the study and at the end of the study after 6 months. Participants included in two groups. Group (A) received resisted exercise training on some resistance machines where; group (B) received treadmill exercise training.
- Conditions
- Chronic Kidney Diseases
- Being tested
- resisted exercise training on some resistance machines, treadmill exercise training
- Medical subject headings
- Renal Insufficiency, Chronic
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
resisted exercise training on some resistance machinesOther
resistance exercises on some resistance machines, 3 sessions of exercise training /week
treadmill exercise trainingOther
treadmill aerobic exercise (intensity equal 60-80 % of each individual maximum heart rate)
| Study group | Role | What they receive |
|---|---|---|
| Group (A) | Experimental | Participants received resisted exercise training on some resistance machines Receives: Other: resisted exercise training on some resistance machines |
| group (B) | Experimental | Participants received treadmill exercise training Receives: Other: treadmill exercise training |
What is being measured
The primary outcome is the main question the study is designed to answer.
serum osteoprotegerin (OPG)
An overnight fasting venous blood sample was drained, centrifuged and stored at -70 °C
Measured: at baseline and after six month
receptor activator of nuclear factor kappa B ligand
An overnight fasting venous blood sample was drained, centrifuged and stored at -70 °C
Measured: at baseline and after six month
Secondary outcomes (1)
Bone mineral density (BMD)
BMD of lumbar spine (L1-L4), proximal femur and distal radius was measured with dual-energy X-ray absorptiometry (DEXA).
Measured: at baseline and after six month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Jun 2026
- Study start1 Dec 2025
- Primary completion30 May 2026
- Study completion30 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Kidney DiseasesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants included in two groups. Group (A) received resisted exercise training on some resistance machines where; group (B) received treadmill exercise training
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Badr University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mona Mohamed Abdelkhalek, Badr University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07628621
- Sponsor's protocol ID
- SU.REC.2025(45H)
- Acronym
- intervention
- Status last verified
- Jun 2026
- First submitted
- 1 Jun 2026
- Last updated
- 5 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Aerobic Versus Resistance Exercise On Bone Metabolism Markers In Chronic Kidney Disease
- ClinicalTrials.gov ID
- NCT07628621
- Acronym / sponsor ID
- intervention / SU.REC.2025(45H)
- Conditions
- Chronic Kidney Diseases
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Badr UniversityUniversity, hospital or other
- Study start
- 1 Dec 2025 (actual)
- Primary completion
- 30 May 2026 (actual)
- Study completion
- 30 May 2026 (actual)
- First posted
- 5 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Sixty chronic kidney disease patients, Measurement of bone turnover markers done prior to the study and at the end of the study after 6 months.
Detailed description
Sixty chronic kidney disease patients, Measurement of bone turnover markers done prior to the study and at the end of the study after 6 months. Participants included in two groups. Group (A) received resisted exercise training on some resistance machines where; group (B) received treadmill exercise training.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
- Model description
- Participants included in two groups. Group (A) received resisted exercise training on some resistance machines where; group (B) received treadmill exercise training
| Arm | Type | Receives |
|---|---|---|
| Group (A) | Experimental | Other: resisted exercise training on some resistance machinesParticipants received resisted exercise training on some resistance machines |
| group (B) | Experimental | Other: treadmill exercise trainingParticipants received treadmill exercise training |
Who may qualify
- Ages
- 30 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Non-smokers,
- no alcohol consumption
- no intake of hormone replacement therapy
- mass index ranged from 20-24 kg/m2.
Key exclusion criteria (6 listed)
- diabetes disorders
- hypertension disorders
- cardiac disorders
- musculoskeletal disorders
- endocrine disorders
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| resisted exercise training on some resistance machinesresistance exercises on some resistance machines, 3 sessions of exercise training /week | Other | Group (A) |
| treadmill exercise trainingtreadmill aerobic exercise (intensity equal 60-80 % of each individual maximum heart rate) | Other | group (B) |
Primary outcome
serum osteoprotegerin (OPG)
Time frame: at baseline and after six month
An overnight fasting venous blood sample was drained, centrifuged and stored at -70 °C
receptor activator of nuclear factor kappa B ligand
Time frame: at baseline and after six month
An overnight fasting venous blood sample was drained, centrifuged and stored at -70 °C
1 secondary outcome
Bone mineral density (BMD)
Time frame: at baseline and after six month
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing resisted exercise training on some resistance machines and treadmill exercise training in people with Chronic Kidney Diseases, run by Badr University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
serum osteoprotegerin (OPG) (time frame: at baseline and after six month). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Jun 2026.