Stroke (CVA) or TIANCT07629882
Functional Electrical Stimulation Versus Whole-Body Vibration in Post-Stroke Rehabilitation
A study testing Functional Electrical Stimulation and Whole Body Vibration Training in people with Stroke (CVA) or TIA, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study will compare the effects of Functional Electrical Stimulation (FES) and Whole Body Vibration Training (WBVT) on lower limb motor control, balance, and physical performance in post-stroke patients. Read more about this study
- Who is it for?
- Ages 35 to 70 years
- Conditions the study is for
- Stroke (CVA) or TIA
- What is being tested?
- Functional Electrical Stimulation and Whole Body Vibration Training
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 sitePakistan
- Study dates
- 5 Jun 2025to 6 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- the patient is between the ages of 35 and 70.
- Both male and female participants will be included.
- Chronic post-stroke patients from 6 months to 1 year.
- Stroke patients who have a neurological impairment.
- Individuals who experienced a single stroke in either the left or right hemisphere of the brain.
- Lower limb motor impairment with Fugl-Meyer Lower Extremity Score ≤ 28.
- Barthel Index Score ≥ 60.
- Berg Balance Scale Score ≥ 21.
Who cannot join
- patients suffering from unstable cardiac condition, severe hypertension, congestive heart failure, aphasia, or cognitive impairments for which exercises are contraindicated.
- Patients with recurrent stroke.
- Patients undergoing other form of lower limb stimulation therapy concurrently.
- Severe orthopedic conditions or joint deformities affecting lower limb.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparative Effects of Functional Electrical Stimulation and Whole Body Vibration Training on Lower Limb Motor Control, Balance and Physical Performance in Post-Stroke Patients
This study will compare the effects of Functional Electrical Stimulation (FES) and Whole Body Vibration Training (WBVT) on lower limb motor control, balance, and physical performance in post-stroke patients. It will be a single-blinded randomized clinical trial including 34 participants, who will be allocated into two groups. Both groups will receive their respective interventions 4 days per week for 8 weeks. Outcomes will be assessed at baseline and after 8 weeks using the Fugl-Meyer Assessment for lower extremity motor control, Berg Balance Scale for balance, and Barthel Index for physical performance.
Read the detailed description
Stroke is an acute focal injury of the central nervous system caused by a vascular source, which results in neurological deficits and can cause disability or death. Stroke can lead to motor weakness, sensory deficiency and loss of motor control. Patients who have had a stroke frequently experience issues with their balance, gait and physical performance. Whole-Body Vibration Training (WBVT) is a non-pharmacological intervention that transmits vibration stimulation throughout the body and has demonstrated promise in improving balance, mobility, and physical function in stroke rehabilitation. Functional Electrical Stimulation (FES) is a rehabilitation technique that helps stroke survivors regain motor skills by stimulating certain nerves with electrical impulses applied via the skin's surface, which causes paretic muscles to move. FES can be utilized to improve physical performance, muscle strength, and balance in stroke patients. Strokes frequently lead to poor physical performance, diminished balance, and impaired lower limb motor control, all of which have an adverse effect on daily functioning and quality of life. This study aims to compare the effects of Functional Electrical Stimulation and Whole Body Vibration Training on lower limb motor control, balance, and physical performance in post-stroke patients.
- Conditions
- Stroke (CVA) or TIA
- Being tested
- Functional Electrical Stimulation, Whole Body Vibration Training
- Keywords
- Functional Electrical Stimulation (FES), Stroke Rehabilitation, Physical Performance, Balance, Lower Limb Motor Control, Whole Body Vibration Training (WBVT)
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Functional Electrical StimulationDevice
Also called FES, Neuromuscular Electrical Stimulation, Electrical Stimulation Therapy
Functional Electrical Stimulation will be delivered transcutaneously to selected lower limb muscles for 8 weeks. Stimulation will target tibialis anterior, quadriceps, hamstrings, peroneal muscles, and other lower limb muscles according to patient need and tolerance. The intervention will use biphasic symmetrical pulsed current with progressive intensity, duration, and functional movement integration. Treatment will be supervised by a physiotherapist, and outcomes will be assessed at baseline and after 8 weeks.
Whole Body Vibration TrainingDevice
Also called Whole Body Vibration, WBV Training
Whole Body Vibration Training will be delivered using a vibration platform for 8 weeks. Participants will perform progressive lower limb activities including standing, semi-squat, heel raises, dynamic squatting, side-to-side weight shifting, and one-leg stance exercises. Frequency, duration, and difficulty will be progressed according to patient tolerance under physiotherapist supervision.
| Study group | Role | What they receive |
|---|---|---|
| Functional Electrical Stimulation Group | Experimental | Participants in this arm will receive transcutaneous Functional Electrical Stimulation for lower limb rehabilitation for 8 weeks. Stimulation will be applied to selected lower limb muscles including tibialis anterior, quadriceps, hamstrings, and peroneal muscles. Treatment parameters will progress according to tolerance, including intensity, session duration, and functional movement integration. Outcomes will be assessed at baseline and after 8 weeks. Receives: Device: Functional Electrical Stimulation |
| Whole Body Vibration Training Group | Active comparator | Participants in this arm will receive Whole Body Vibration Training using a vibration platform for 8 weeks. Training will include progressive activities such as standing, semi-squat, heel raises, dynamic squatting, side-to-side weight shifting, and one-leg stance. Vibration frequency, duration, and exercise difficulty will be gradually progressed according to tolerance. Outcomes will be assessed at baseline and after 8 weeks.
After this, go to Interventions and add Functional Electrical Stimulation and Whole Body Vibration Training, then assign each intervention to its matching arm. Receives: Device: Whole Body Vibration Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
lower Limb Motor Control
Assessed using the Fugl-Meyer Assessment for Lower Extremity.
Measured: Baseline and 8 weeks post-intervention
Secondary outcomes (2)
Balance
Assessed using the Berg Balance Scale.
Measured: Baseline and 8 weeks post-intervention
Physical Performance
Assessed using the Barthel Index Scale.
Measured: Baseline and 8 weeks post-intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Jun 2026
- Study start5 Jun 2025
- Primary completion6 Jul 2026 (estimated)
- Study completion6 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Stroke (CVA) or TIAStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly allocated into two equal groups: Functional Electrical Stimulation group and Whole Body Vibration Training group.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 34 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Ambreen Iqbal IQBAL, Study chair, Riphah International University Role
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07629882
- Sponsor's protocol ID
- NOOR NAZISH
- Status last verified
- Jun 2026
- First submitted
- 1 Jun 2026
- Last updated
- 5 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: The individual participant data sharing plan has not yet been finalized.
Study at a glance
From the registry record, last updated by the sponsor on 5 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Functional Electrical Stimulation and Whole Body Vibration Training on Lower Limb Motor Control, Balance and Physical Performance in Post-Stroke Patients
- ClinicalTrials.gov ID
- NCT07629882
- Acronym / sponsor ID
- NOOR NAZISH
- Conditions
- Stroke (CVA) or TIA
- Keywords
- Functional Electrical Stimulation (FES), Stroke Rehabilitation, Physical Performance, Balance, Lower Limb Motor Control, Whole Body Vibration Training (WBVT)
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 34 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 5 Jun 2025 (actual)
- Primary completion
- 6 Jul 2026 (estimated)
- Study completion
- 6 Aug 2026 (estimated)
- First posted
- 5 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will compare the effects of Functional Electrical Stimulation (FES) and Whole Body Vibration Training (WBVT) on lower limb motor control, balance, and physical performance in post-stroke patients. It will be a single-blinded randomized clinical trial including 34 participants, who will be allocated into two groups. Both groups will receive their respective interventions 4 days per week for 8 weeks. Outcomes will be assessed at baseline and after 8 weeks using the Fugl-Meyer Assessment for lower extremity motor control, Berg Balance Scale for balance, and Barthel Index for physical performance.
Detailed description
Stroke is an acute focal injury of the central nervous system caused by a vascular source, which results in neurological deficits and can cause disability or death. Stroke can lead to motor weakness, sensory deficiency and loss of motor control. Patients who have had a stroke frequently experience issues with their balance, gait and physical performance. Whole-Body Vibration Training (WBVT) is a non-pharmacological intervention that transmits vibration stimulation throughout the body and has demonstrated promise in improving balance, mobility, and physical function in stroke rehabilitation. Functional Electrical Stimulation (FES) is a rehabilitation technique that helps stroke survivors regain motor skills by stimulating certain nerves with electrical impulses applied via the skin's surface, which causes paretic muscles to move. FES can be utilized to improve physical performance, muscle strength, and balance in stroke patients. Strokes frequently lead to poor physical performance, diminished balance, and impaired lower limb motor control, all of which have an adverse effect on daily functioning and quality of life. This study aims to compare the effects of Functional Electrical Stimulation and Whole Body Vibration Training on lower limb motor control, balance, and physical performance in post-stroke patients.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Participants will be randomly allocated into two equal groups: Functional Electrical Stimulation group and Whole Body Vibration Training group.
| Arm | Type | Receives |
|---|---|---|
| Functional Electrical Stimulation Group | Experimental | Device: Functional Electrical StimulationParticipants in this arm will receive transcutaneous Functional Electrical Stimulation for lower limb rehabilitation for 8 weeks. Stimulation will be applied to selected lower limb muscles including tibialis anterior, quadriceps, hamstrings, and peroneal muscles. Treatment parameters will progress according to tolerance, including intensity, session duration, and functional movement integration. Outcomes will be assessed at baseline and after 8 weeks. |
| Whole Body Vibration Training Group | Active comparator | Device: Whole Body Vibration TrainingParticipants in this arm will receive Whole Body Vibration Training using a vibration platform for 8 weeks. Training will include progressive activities such as standing, semi-squat, heel raises, dynamic squatting, side-to-side weight shifting, and one-leg stance. Vibration frequency, duration, and exercise difficulty will be gradually progressed according to tolerance. Outcomes will be assessed at baseline and after 8 weeks. After this, go to Interventions and add Functional Electrical Stimulation and Whole Body Vibration Training, then assign each intervention to its matching arm. |
Who may qualify
- Ages
- 35 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- the patient is between the ages of 35 and 70.
- Both male and female participants will be included.
- Chronic post-stroke patients from 6 months to 1 year.
- Stroke patients who have a neurological impairment.
- Individuals who experienced a single stroke in either the left or right hemisphere of the brain.
Key exclusion criteria (4 listed)
- patients suffering from unstable cardiac condition, severe hypertension, congestive heart failure, aphasia, or cognitive impairments for which exercises are contraindicated.
- Patients with recurrent stroke.
- Patients undergoing other form of lower limb stimulation therapy concurrently.
- Severe orthopedic conditions or joint deformities affecting lower limb.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Functional Electrical StimulationAlso: FES, Neuromuscular Electrical Stimulation, Electrical Stimulation TherapyFunctional Electrical Stimulation will be delivered transcutaneously to selected lower limb muscles for 8 weeks. Stimulation will target tibialis anterior, quadriceps, hamstrings, peroneal muscles, and other lower limb muscles according to patient need and tolerance. The intervention will use biphasic symmetrical pulsed current with progressive intensity, duration, and functional movement integration. Treatment will be supervised by a physiotherapist, and outcomes will be assessed at baseline and after 8 weeks. | Device | Functional Electrical Stimulation Group |
| Whole Body Vibration TrainingAlso: Whole Body Vibration, WBV TrainingWhole Body Vibration Training will be delivered using a vibration platform for 8 weeks. Participants will perform progressive lower limb activities including standing, semi-squat, heel raises, dynamic squatting, side-to-side weight shifting, and one-leg stance exercises. Frequency, duration, and difficulty will be progressed according to patient tolerance under physiotherapist supervision. | Device | Whole Body Vibration Training Group |
Primary outcome
lower Limb Motor Control
Time frame: Baseline and 8 weeks post-intervention
Assessed using the Fugl-Meyer Assessment for Lower Extremity.
2 secondary outcomes
Balance
Time frame: Baseline and 8 weeks post-intervention
Physical Performance
Time frame: Baseline and 8 weeks post-intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Jun 2026.
- Individual participant dataSharing planned: No. The individual participant data sharing plan has not yet been finalized.
Related trials for Stroke (CVA) or TIA
Not yet recruitingPhase 3
Cilostazol for Prevention of Recurrent Stroke Trial
Stroke Recurrence, Myocardial Infarction
RecruitingObservational study
Natural History of Stroke: Cause and Development
Brain Disease, Ischemic Attack, Transient
Recruiting
Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke
Stroke, Stroke (CVA) or Transient Ischemic Attack
Recruiting
Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)
Stroke, Acute, Stroke
Recruiting
Optimized Recruitment to Drive Equitable Research in Stroke, Empowering Decision-making (ORDERed)
Stroke, Stroke (CVA) or Transient Ischemic Attack
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ambreen Iqbal IQBAL study chair
Riphah International University Role
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Functional Electrical Stimulation and Whole Body Vibration Training in people with Stroke (CVA) or TIA, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 5 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
lower Limb Motor Control (time frame: Baseline and 8 weeks post-intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Jun 2026.