Patellofemoral Pain SyndromeNCT07633782
High-Intensity Focused Electromagnetic Therapy on Patients With Patellofemoral Pain Syndrome
A study testing True High-Intensity Focused Electromagnetic Therapy and Traditional Physiotherapy in people with Patellofemoral Pain Syndrome, run by Middle East University.
Trial summary
Evaluate the effect of High-Intensity Focused Electromagnetic Therapy on pain, quadriceps strength, and quality of life in patients with patellofemoral pain syndrome Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- Patellofemoral Pain Syndrome
- What is being tested?
- True High-Intensity Focused Electromagnetic Therapy and Traditional Physiotherapy
- Type of treatment
- Medical device
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 60 participants
- Where
- No sites listed yet
- Study dates
- 12 Jun 2026to 8 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Clinical diagnosis of patellofemoral pain syndrome (anterior or peripatellar knee pain aggravated by at least two activities such as stair climbing, prolonged sitting, squatting, or running).
- Symptoms persisting for at least 3 months.
Who cannot join
- History of previous knee surgery or trauma (e.g., ligamentous laxity, meniscal tear, or patellar fracture).
- Concomitant knee pathology (e.g., tibiofemoral osteoarthritis, patellar tendinopathy, or plica syndrome).
- Presence of metallic implants, pacemakers, or electrical medical devices in the body .
- Recent corticosteroid or hyaluronic acid injection into the affected knee within the last 3 months.
- Pregnancy.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Effect of High-Intensity Focused Electromagnetic Therapy on Pain and Quality of Life in Patients With Patellofemoral Pain Syndrome: A Randomized Controlled Trial
Evaluate the effect of High-Intensity Focused Electromagnetic Therapy on pain, quadriceps strength, and quality of life in patients with patellofemoral pain syndrome
Read the detailed description
Patients diagnosed with patellofemoral pain syndrome will be recruited from outpatient physical therapy clinics. Following a comprehensive clinical screening, eligible participants will be randomly assigned into two parallel groups:
The Study Group: Will receive true High-Intensity Focused Electromagnetic Therapy sessions plus a traditional physiotherapy program for 8 weeks.
The Control Group: Will receive sham High-Intensity Focused Electromagnetic Therapy sessions plus the same traditional physiotherapy program for 8 weeks.
- Conditions
- Patellofemoral Pain Syndrome
- Being tested
- True High-Intensity Focused Electromagnetic Therapy, Sham High-Intensity Focused Electromagnetic Therapy, Traditional Physiotherapy
- Medical subject headings
- Patellofemoral Pain Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
True High-Intensity Focused Electromagnetic TherapyDevice
20-30 minute sessions, 2-3 times per week for 8 weeks at a clinically effective, tolerable intensity level designed to elicit supramaximal contractions for the quadriceps muscle.
Sham High-Intensity Focused Electromagnetic TherapyDevice
The device protocol, application time, and acoustic feedback will the same as the experimental arm, but with the device in the off state and no muscular contractions in the quadriceps muscle .
Traditional PhysiotherapyOther
Standard rehabilitation program including patellar mobilization with quadriceps and hip abductor strengthening.
| Study group | Role | What they receive |
|---|---|---|
| Study group | Active comparator | Not described Receives: Device: True High-Intensity Focused Electromagnetic Therapy; Other: Traditional Physiotherapy |
| Control group | Sham comparator | Not described Receives: Device: Sham High-Intensity Focused Electromagnetic Therapy; Other: Traditional Physiotherapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain level
Visual Analog Scale will be used to assess pain
Measured: Baseline and after 8 weeks
Secondary outcomes (2)
Quadriceps muscle strength
Isokinetic dynamometry will be used for assessing quadriceps muscle strength
Measured: Baseline and after 8 weeks
Health-related quality of life
Short Form-12 Health Survey (SF-12) will be used to assess QoL
Measured: Baseline and after 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jun 2026
- Study start12 Jun 2026 (estimated)
- Primary completion1 Oct 2026 (estimated)
- Study completion8 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Patellofemoral Pain SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Middle East University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Saher Lotfy El Gayar, Middle East University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07633782
- Sponsor's protocol ID
- Electromagnetic Treatment
- Status last verified
- Jun 2026
- First submitted
- 2 Jun 2026
- Last updated
- 8 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of High-Intensity Focused Electromagnetic Therapy on Pain and Quality of Life in Patients With Patellofemoral Pain Syndrome: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07633782
- Acronym / sponsor ID
- Electromagnetic Treatment
- Conditions
- Patellofemoral Pain Syndrome
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Middle East UniversityUniversity, hospital or other
- Study start
- 12 Jun 2026 (estimated)
- Primary completion
- 1 Oct 2026 (estimated)
- Study completion
- 8 Oct 2026 (estimated)
- First posted
- 8 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Evaluate the effect of High-Intensity Focused Electromagnetic Therapy on pain, quadriceps strength, and quality of life in patients with patellofemoral pain syndrome
Detailed description
Patients diagnosed with patellofemoral pain syndrome will be recruited from outpatient physical therapy clinics. Following a comprehensive clinical screening, eligible participants will be randomly assigned into two parallel groups:
The Study Group: Will receive true High-Intensity Focused Electromagnetic Therapy sessions plus a traditional physiotherapy program for 8 weeks.
The Control Group: Will receive sham High-Intensity Focused Electromagnetic Therapy sessions plus the same traditional physiotherapy program for 8 weeks.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Study group | Active comparator | Device: True High-Intensity Focused Electromagnetic Therapy, Other: Traditional Physiotherapy |
| Control group | Sham comparator | Device: Sham High-Intensity Focused Electromagnetic Therapy, Other: Traditional Physiotherapy |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Clinical diagnosis of patellofemoral pain syndrome (anterior or peripatellar knee pain aggravated by at least two activities such as stair climbing, prolonged sitting, squatting, or running).
- Symptoms persisting for at least 3 months.
Key exclusion criteria (5 listed)
- History of previous knee surgery or trauma (e.g., ligamentous laxity, meniscal tear, or patellar fracture).
- Concomitant knee pathology (e.g., tibiofemoral osteoarthritis, patellar tendinopathy, or plica syndrome).
- Presence of metallic implants, pacemakers, or electrical medical devices in the body .
- Recent corticosteroid or hyaluronic acid injection into the affected knee within the last 3 months.
- Pregnancy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| True High-Intensity Focused Electromagnetic Therapy20-30 minute sessions, 2-3 times per week for 8 weeks at a clinically effective, tolerable intensity level designed to elicit supramaximal contractions for the quadriceps muscle. | Device | Study group |
| Sham High-Intensity Focused Electromagnetic TherapyThe device protocol, application time, and acoustic feedback will the same as the experimental arm, but with the device in the off state and no muscular contractions in the quadriceps muscle . | Device | Control group |
| Traditional PhysiotherapyStandard rehabilitation program including patellar mobilization with quadriceps and hip abductor strengthening. | Other | Control group, Study group |
Primary outcome
Pain level
Time frame: Baseline and after 8 weeks
Visual Analog Scale will be used to assess pain
2 secondary outcomes
Quadriceps muscle strength
Time frame: Baseline and after 8 weeks
Health-related quality of life
Time frame: Baseline and after 8 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jun 2026.
- Individual participant dataSharing planned: No
Related trials for Patellofemoral Pain Syndrome
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Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal Disorders
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing True High-Intensity Focused Electromagnetic Therapy and Traditional Physiotherapy in people with Patellofemoral Pain Syndrome, run by Middle East University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Saher Lotfy Elgayar, Ph.D (+201020429911, saherlotfy020@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain level (time frame: Baseline and after 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jun 2026.