Compare Two Surgical Approaches Used in Total Hip ArthroplastyNCT07633925
Short-term Results of SuperPATH Versus Direct Lateral Approach In Primary Total Hip Arthroplasty: A Randomized Controlled Study.
A study testing Surgical approaches: direct lateral approach for the hip and SuperPATH approach in people with Compare Two Surgical Approaches Used in Total Hip Arthroplasty, run by Assiut University at 1 site in Egypt.
Trial summary
Total hip arthroplasty (THA) has shown great success in relieving joint pain and disability and has been a procedure of choice for the treatment of end-stage degenerative joint diseases and trauma. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Compare Two Surgical Approaches Used in Total Hip Arthroplasty
- What is being tested?
- Surgical approaches: direct lateral approach for the hip and SuperPATH approach
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jul 2026to Jul 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Primary total hip arthroplasty.
- Age > 18 years.
- Body mass index < 40 kg/m2.
- Able to ambulate preoperative.
Who cannot join
- Hip deformity (acetabular or femoral).
- Ankylosed hips.
- Severe osteoporosis.
- Neuromuscular disorders.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Mohamed Mostafa Alaa eldin and el aziz, Assistant professor contact
About this study
Total hip arthroplasty (THA) has shown great success in relieving joint pain and disability and has been a procedure of choice for the treatment of end-stage degenerative joint diseases and trauma.
There are multiple surgical approaches for THA, including the traditional posterior approach, anterior approach, lateral approach, anterolateral approach and posterolateral approach; each has its advantages and complications.
Read more
Modified direct lateral approach is considered as standard, most commonly used and familiar in Assiut university Arthroplasty centre. Yet it may cause abductor weakness, post operative pain, prolonged rehabilitation time and more blood loss.
In the past two decades, the group of micro-posterior approaches was introduced. In 2004 Stephen Murphy developed the Supecapsular (SuperCap) approach, preparing the hip insitu to reduce soft tissue traumatization caused by the dislocation manoeuvre used in the conventional posterior approach. , In 2008 Brad Penenberg developed the percutaneously-assisted total hip (PATH) app, a tissue-sparing approach leading through the interval between gluteus medius and the conjoined tendon of the external rotators.
In2011, James Chow described the supercapsular percutaneously-assisted total hip (SuperPATH) approach, the most Important features of SuperPATH are the following: (a) muscle sparing between gluteus medius and piriformis without detaching external rotator tendons or disrupting the hip capsule, (b) femur preparation first without dislocation (c) percutaneous acetabular preparation.
SuperPATH approach is designed to reduce soft tissue trauma and so blood loss, post operative pain, improve joint stability and allow earlier mobilization of patients.
Despite the theoretical advantages of the SuperPATH approach, its adoption remains limited compared with conventional surgical approaches. Furthermore, there is ongoing debate regarding its clinical superiority in terms of functional outcomes, complication rates and implant position.
Aim of our study is to evaluate the clinical and functional outcomes of total hip arthroplasty performed using SuperPATH compared to modified direct lateral approach.
- Being tested
- Surgical approaches: direct lateral approach for the hip and SuperPATH approach
- Keywords
- SuperPATH, total hip arthroplasty
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Surgical approaches: direct lateral approach for the hip and SuperPATH approachProcedure or surgery
Direct lateral approach is approach through the intra muscular septum of gluteus medial muscle SuperPATH approach is minimally invasive posterolateral approach for the hip
| Study group | Role | What they receive |
|---|---|---|
| Direct lateral approach | Experimental | total hip arthroplasty via direct lateral approach Receives: Procedure: Surgical approaches: direct lateral approach for the hip and SuperPATH approach |
| SuperPATH | Experimental | This arm will include patients who will undergo total hip arthroplasty via SuperPATH approach Receives: Procedure: Surgical approaches: direct lateral approach for the hip and SuperPATH approach |
What is being measured
The primary outcome is the main question the study is designed to answer.
Harris hip score
Measured: Immediately post operative 3 months 6 months One year Two years
Secondary outcomes (3)
Oxford hip score
Measured: Immediately post operative 3 months 6 months One year Two years
Visual analogue score
Measured: Immediately post operative 3 months 6 months One year Two years
Operative time in minutes
Measured: Duration of the operation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jun 2026
- Study start1 Jul 2026 (estimated)
- Primary completionJul 2028 (estimated)
- Study completionJul 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Compare Two Surgical Approaches Used in Total Hip ArthroplastyStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- We will divide population into two groups One group for direct lateral approach and the other for SuperPATH approach
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Islam Mohamed Abd El Hameed, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07633925
- Sponsor's protocol ID
- ORTHO-2026-015
- Status last verified
- Jun 2026
- First submitted
- 30 May 2026
- Last updated
- 8 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 8 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Short-term Results of SuperPATH Versus Direct Lateral Approach In Primary Total Hip Arthroplasty: A Randomized Controlled Study.
- ClinicalTrials.gov ID
- NCT07633925
- Acronym / sponsor ID
- ORTHO-2026-015
- Keywords
- SuperPATH, total hip arthroplasty
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 1 Jul 2026 (estimated)
- Primary completion
- Jul 2028 (estimated)
- Study completion
- Jul 2029 (estimated)
- First posted
- 8 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Total hip arthroplasty (THA) has shown great success in relieving joint pain and disability and has been a procedure of choice for the treatment of end-stage degenerative joint diseases and trauma.
There are multiple surgical approaches for THA, including the traditional posterior approach, anterior approach, lateral approach, anterolateral approach and posterolateral approach; each has its advantages and complications.
Modified direct lateral approach is considered as standard, most commonly used and familiar in Assiut university Arthroplasty centre. Yet it may cause abductor weakness, post operative pain, prolonged rehabilitation time and more blood loss.
In the past two decades, the group of micro-posterior approaches was introduced. In 2004 Stephen Murphy developed the Supecapsular (SuperCap) approach, preparing the hip insitu to reduce soft tissue traumatization caused by the dislocation manoeuvre used in the conventional posterior approach. , In 2008 Brad Penenberg developed the percutaneously-assisted total hip (PATH) app, a tissue-sparing approach leading through the interval between gluteus medius and the conjoined tendon of the external rotators.
In2011, James Chow described the supercapsular percutaneously-assisted total hip (SuperPATH) approach, the most Important features of SuperPATH are the following: (a) muscle sparing between gluteus medius and piriformis without detaching external rotator tendons or disrupting the hip capsule, (b) femur preparation first without dislocation (c) percutaneous acetabular preparation.
SuperPATH approach is designed to reduce soft tissue trauma and so blood loss, post operative pain, improve joint stability and allow earlier mobilization of patients.
Despite the theoretical advantages of the SuperPATH approach, its adoption remains limited compared with conventional surgical approaches. Furthermore, there is ongoing debate regarding its clinical superiority in terms of functional outcomes, complication rates and implant position.
Aim of our study is to evaluate the clinical and functional outcomes of total hip arthroplasty performed using SuperPATH compared to modified direct lateral approach.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- We will divide population into two groups One group for direct lateral approach and the other for SuperPATH approach
| Arm | Type | Receives |
|---|---|---|
| Direct lateral approach | Experimental | Procedure: Surgical approaches: direct lateral approach for the hip and SuperPATH approachtotal hip arthroplasty via direct lateral approach |
| SuperPATH | Experimental | Procedure: Surgical approaches: direct lateral approach for the hip and SuperPATH approachThis arm will include patients who will undergo total hip arthroplasty via SuperPATH approach |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Primary total hip arthroplasty.
- Age > 18 years.
- Body mass index < 40 kg/m2.
- Able to ambulate preoperative.
Key exclusion criteria (4 listed)
- Hip deformity (acetabular or femoral).
- Ankylosed hips.
- Severe osteoporosis.
- Neuromuscular disorders.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Surgical approaches: direct lateral approach for the hip and SuperPATH approachDirect lateral approach is approach through the intra muscular septum of gluteus medial muscle SuperPATH approach is minimally invasive posterolateral approach for the hip | Procedure or surgery | Direct lateral approach, SuperPATH |
Primary outcome
Harris hip score
Time frame: Immediately post operative 3 months 6 months One year Two years
3 secondary outcomes
Oxford hip score
Time frame: Immediately post operative 3 months 6 months One year Two years
Visual analogue score
Time frame: Immediately post operative 3 months 6 months One year Two years
Operative time in minutes
Time frame: Duration of the operation
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jun 2026.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mohamed Mostafa Alaa eldin and el aziz, Assistant professor contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Surgical approaches: direct lateral approach for the hip and SuperPATH approach in people with Compare Two Surgical Approaches Used in Total Hip Arthroplasty, run by Assiut University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Islam Mohamed Abd el hameed, Assistant lecturer (0201016329653, islammohamed846@yahoo.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Harris hip score (time frame: Immediately post operative 3 months 6 months One year Two years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jun 2026.