Stroke SequelaeCESTONCT07635069
Cognitive Effectiveness of Somatotherapy and Occupational Therapy in Post-Stroke Patients.
An observational study of Stroke Sequelae and Cognitive Impairment, run by Iqra National University at 1 site in Pakistan.
Trial summary
The objective of this study was to evaluate the cognitive effectiveness of somatotherapy and occupational therapy in post-stroke patients by measuring their cognitive potential outcomes using the Montreal Cognitive Assessment (MoCA) test. Read more about this study
- Who is it for?
- Ages 30 years and older
- Conditions the study is for
- Stroke Sequelae, Cognitive Impairment
- What is being tested?
- Somatotherapy and Occupational Therapy
- How many people
- 50 participants
- Where
- 1 sitePakistan
- Study dates
- 3 Jan 2023to 25 Dec 2025
- How long will I take part?
- 50 Months
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: 50 post-stroke patients (30 males and 20 females) who were referred to the Department of Physical Therapy at King Hospital, Swat, Pakistan between 2018 and 2019 for cognitive rehabilitation. Participants were adult stroke patients (approximate mean age around 60 years) with either ischemic or hemorrhagic stroke who received 4 weeks of inpatient combined somatotherapy and occupational therapy.
Who may be able to join
- Adults aged 30 years and above
- Diagnosed with ischemic or hemorrhagic stroke (first-ever or recurrent)
- Referred to physical therapy department for cognitive rehabilitation
- Received somatotherapy and occupational therapy during hospitalization
- Able to undergo MoCA (Montreal Cognitive Assessment) testing
Who cannot join
- Severe speech impairment (aphasia) that prevents reliable cognitive testing
- Significant visual impairment that interferes with MoCA testing
- Significant hearing impairment that interferes with MoCA testing
- Inability to participate in therapy sessions.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Cognitive Effectiveness of Somatotherapy & Occupational Therapy in Post-Stroke Patients
The objective of this study was to evaluate the cognitive effectiveness of somatotherapy and occupational therapy in post-stroke patients by measuring their cognitive potential outcomes using the Montreal Cognitive Assessment (MoCA) test.
Read the detailed description
Stroke is a leading cause of death and long-term disability worldwide. Cognitive impairment is a common and disabling consequence of stroke that significantly affects patients' functional independence and quality of life.
Somatotherapy (targeted physical and sensorimotor therapy) and occupational therapy (focused on activities of daily living) are frequently used rehabilitation approaches, but their combined effect on cognitive recovery in post-stroke patients requires further evaluation.
This was a single-center, retrospective observational study conducted at the department of physical therapy, King Hospital, Swat, Pakistan. Medical records of 50 post-stroke patients (30 males, 20 females; age range 30-60 years) who received inpatient rehabilitation between 2018 and 2019 were analyzed.
Participants
- Conditions
- Stroke Sequelae, Cognitive Impairment
- Being tested
- Somatotherapy and Occupational Therapy
- Keywords
- stroke, stroke sequelae, Cognitive Impairement
- Medical subject headings
- Cognitive Dysfunction, Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Somatotherapy and Occupational TherapyOther
Combined somatotherapy and occupational therapy delivered during inpatient hospitalization.
Somatotherapy consisted of structured sensorimotor and physical therapy targeting body awareness, movement, balance, and coordination. Occupational therapy focused on patient-specific, task-oriented training in activities of daily living (ADLs) such as self-care, functional mobility, and cognitive integration during daily tasks.
Patients received 35-minute sessions, 5 days per week for 4 consecutive weeks. Therapy was customized according to individual patient needs and used equipment including adjustable tables, chairs, wheelchairs, and assistive aids (splints, glasses, etc.).
What is being measured
The primary outcome is the main question the study is designed to answer.
Montreal Cognitive Assessment
To detect mild cognitive impairment and assess for early stages of dementia. This scale utilizes a minimum value of 0 and a maximum value of 30, where higher scores mean a better outcome (a score of 26 or above is considered normal, while a score of 22 suggests mild cognitive impairment.
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jun 2026
- Study start3 Jan 2023
- Primary completion25 Dec 2025
- Study completion25 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Stroke SequelaeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Other
- Enrolment
- 50 participants (actual)
- Target duration
- 50 Months
Sponsor and investigators
- Lead sponsor
- Iqra National University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Muslim khan, Iqra National University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07635069
- Sponsor's protocol ID
- IQRA-00023
- Other IDs
- Iqra-023
- Acronym
- CESTO
- Status last verified
- Jun 2026
- First submitted
- 8 May 2026
- Last updated
- 9 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: ndividual participant data will not be shared publicly. The study is a small retrospective analysis based on hospital medical records. Sharing IPD is not planned due to: Ethical and privacy concerns (patient confidentiality and data protection regulations). The retrospective nature of the study with no prior consent obtained from participants for data sharing. Local institutional policies at King Hospital regarding data sharing.
Study at a glance
From the registry record, last updated by the sponsor on 9 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Cognitive Effectiveness of Somatotherapy & Occupational Therapy in Post-Stroke Patients
- ClinicalTrials.gov ID
- NCT07635069
- Acronym / sponsor ID
- CESTO / IQRA-00023
- Conditions
- Stroke Sequelae, Cognitive Impairment
- Keywords
- stroke, stroke sequelae, Cognitive Impairement
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Iqra National UniversityUniversity, hospital or other
- Study start
- 3 Jan 2023 (actual)
- Primary completion
- 25 Dec 2025 (actual)
- Study completion
- 25 Dec 2025 (actual)
- First posted
- 9 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective of this study was to evaluate the cognitive effectiveness of somatotherapy and occupational therapy in post-stroke patients by measuring their cognitive potential outcomes using the Montreal Cognitive Assessment (MoCA) test.
Detailed description
Stroke is a leading cause of death and long-term disability worldwide. Cognitive impairment is a common and disabling consequence of stroke that significantly affects patients' functional independence and quality of life.
Somatotherapy (targeted physical and sensorimotor therapy) and occupational therapy (focused on activities of daily living) are frequently used rehabilitation approaches, but their combined effect on cognitive recovery in post-stroke patients requires further evaluation.
This was a single-center, retrospective observational study conducted at the department of physical therapy, King Hospital, Swat, Pakistan. Medical records of 50 post-stroke patients (30 males, 20 females; age range 30-60 years) who received inpatient rehabilitation between 2018 and 2019 were analyzed.
Participants
Study design
- Observational model
- Cohort
- Time perspective
- Other
- Target follow-up
- 50 Months
Who may qualify
- Ages
- 30 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- 50 post-stroke patients (30 males and 20 females) who were referred to the Department of Physical Therapy at King Hospital, Swat, Pakistan between 2018 and 2019 for cognitive rehabilitation. Participants were adult stroke patients (approximate mean age around 60 years) with either ischemic or hemorrhagic stroke who received 4 weeks of inpatient combined somatotherapy and occupational therapy.
Key inclusion criteria (5 listed)
- Adults aged 30 years and above
- Diagnosed with ischemic or hemorrhagic stroke (first-ever or recurrent)
- Referred to physical therapy department for cognitive rehabilitation
- Received somatotherapy and occupational therapy during hospitalization
- Able to undergo MoCA (Montreal Cognitive Assessment) testing
Key exclusion criteria (4 listed)
- Severe speech impairment (aphasia) that prevents reliable cognitive testing
- Significant visual impairment that interferes with MoCA testing
- Significant hearing impairment that interferes with MoCA testing
- Inability to participate in therapy sessions.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Somatotherapy and Occupational TherapyCombined somatotherapy and occupational therapy delivered during inpatient hospitalization. Somatotherapy consisted of structured sensorimotor and physical therapy targeting body awareness, movement, balance, and coordination. Occupational therapy focused on patient-specific, task-oriented training in activities of daily living (ADLs) such as self-care, functional mobility, and cognitive integration during daily tasks. Patients received 35-minute sessions, 5 days per week for 4 consecutive weeks. Therapy was customized according to individual patient needs and used equipment including adjustable tables, chairs, wheelchairs, and assistive aids (splints, glasses, etc.). | Other | – |
Primary outcome
Montreal Cognitive Assessment
Time frame: 4 weeks
To detect mild cognitive impairment and assess for early stages of dementia. This scale utilizes a minimum value of 0 and a maximum value of 30, where higher scores mean a better outcome (a score of 26 or above is considered normal, while a score of 22 suggests mild cognitive impairment.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Jun 2026.
- Individual participant dataSharing planned: No. ndividual participant data will not be shared publicly. The study is a small retrospective analysis based on hospital medical records. Sharing IPD is not planned due to: Ethical and privacy concerns (patient confidentiality and data protection regulations). The retrospective nature of the study with no prior consent obtained from participants for data sharing. Local institutional policies at King Hospital regarding data sharing.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Stroke Sequelae and Cognitive Impairment, run by Iqra National University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Montreal Cognitive Assessment (time frame: 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jun 2026.