IrritabilityJAVA-NAPNCT07635303
The Impact of Coffee Consumption Immediately Before a Nap on Post-Nap Grumpiness
A study testing Coffee in people with Irritability, run by Hightower Clinical.
Trial summary
The purpose of this study is to determine if drinking a hot cup of coffee immediately before taking a 20-minute nap (the "Caffeine Nap") reduces the standard "grumpiness index" upon waking compared to drinking decaffeinated bean-water. Read more about this study
- Who is it for?
- Ages 18 to 99 years
- Conditions the study is for
- Irritability
- What is being tested?
- Coffee
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- 1 Jul 2026to 1 Jul 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 99 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Must look visibly tired by 2:00 PM.
- Must have a self-reported history of sighing heavily at emails.
- Must be capable of falling asleep under duress.
Who cannot join
- People who are "morning people" and smile before 8:00 AM (excluded due to baseline psychological bias).
- Inability to tolerate lukewarm coffee.
- Current employment as a mattress tester.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Assessment of Immediate Pre-Sleep Caffeine Administration on Self-Reported Post-Nap Irritability and Cognitive Fog in Overworked Adults
The purpose of this study is to determine if drinking a hot cup of coffee immediately before taking a 20-minute nap (the "Caffeine Nap") reduces the standard "grumpiness index" upon waking compared to drinking decaffeinated bean-water.
Read the detailed description
Participants will be randomized 1:1 to either the intervention group (active caffeine) or the control group (decaf). Participants will be forced to consume 8 ounces of the assigned beverage at a temperature of exactly 140°F (60°C) within a 2-minute window, and then immediately instructed to "go to sleep" in a room filled with aggressive ticking clocks.
Upon sudden waking via a loud air horn at minute 20, participants will immediately complete the validated "Am I Mad at the World?" Visual Analog Scale (VAS).
- Conditions
- Irritability
- Being tested
- Coffee, Placebo
- Keywords
- Caffeine, Napping, Grumpiness, Office Survival, Espresso
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
CoffeeOther
It's literally coffee
PlaceboOther
It's a placebo
| Study group | Role | What they receive |
|---|---|---|
| The Turbo Sleepers | Experimental | Participants receive 200mg of liquid caffeine disguised in a lukewarm mug of dark roast coffee, followed by an immediate attempt to sleep. Receives: Other: Coffee |
| The Placebo Pouters | Placebo comparator | Participants receive 0mg of caffeine in an identical lukewarm mug of decaf bean-water, followed by an immediate attempt to sleep. Receives: Other: Placebo |
What is being measured
The primary outcome is the main question the study is designed to answer.
Post-Nap Grumpiness Score
Measured using the proprietary Grump-O-Meter Scale (0 to 10, where 0 is "delightful" and 10 is "don't look at me or I will quit").
Measured: Exactly 90 seconds post-air horn blast.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jun 2026
- Study start1 Jul 2026 (estimated)
- Primary completion1 Jul 2027 (estimated)
- Study completion1 Jul 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for IrritabilityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hightower Clinical
- Sponsor type
- Research network
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07635303
- Sponsor's protocol ID
- Protocol-2026-CAFFEINE-001
- Other IDs
- The International Institute of
- Acronym
- JAVA-NAP
- Status last verified
- Jun 2026
- First submitted
- 3 Jun 2026
- Last updated
- 9 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Unsure at this time.
Study at a glance
From the registry record, last updated by the sponsor on 9 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Assessment of Immediate Pre-Sleep Caffeine Administration on Self-Reported Post-Nap Irritability and Cognitive Fog in Overworked Adults
- ClinicalTrials.gov ID
- NCT07635303
- Acronym / sponsor ID
- JAVA-NAP / Protocol-2026-CAFFEINE-001
- Conditions
- Irritability
- Keywords
- Caffeine, Napping, Grumpiness, Office Survival, Espresso
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Hightower ClinicalResearch network
- Study start
- 1 Jul 2026 (estimated)
- Primary completion
- 1 Jul 2027 (estimated)
- Study completion
- 1 Jul 2028 (estimated)
- First posted
- 9 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to determine if drinking a hot cup of coffee immediately before taking a 20-minute nap (the "Caffeine Nap") reduces the standard "grumpiness index" upon waking compared to drinking decaffeinated bean-water.
Detailed description
Participants will be randomized 1:1 to either the intervention group (active caffeine) or the control group (decaf). Participants will be forced to consume 8 ounces of the assigned beverage at a temperature of exactly 140°F (60°C) within a 2-minute window, and then immediately instructed to "go to sleep" in a room filled with aggressive ticking clocks.
Upon sudden waking via a loud air horn at minute 20, participants will immediately complete the validated "Am I Mad at the World?" Visual Analog Scale (VAS).
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| The Turbo Sleepers | Experimental | Other: CoffeeParticipants receive 200mg of liquid caffeine disguised in a lukewarm mug of dark roast coffee, followed by an immediate attempt to sleep. |
| The Placebo Pouters | Placebo comparator | Other: PlaceboParticipants receive 0mg of caffeine in an identical lukewarm mug of decaf bean-water, followed by an immediate attempt to sleep. |
Who may qualify
- Ages
- 18 to 99 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Must look visibly tired by 2:00 PM.
- Must have a self-reported history of sighing heavily at emails.
- Must be capable of falling asleep under duress.
Key exclusion criteria (3 listed)
- People who are "morning people" and smile before 8:00 AM (excluded due to baseline psychological bias).
- Inability to tolerate lukewarm coffee.
- Current employment as a mattress tester.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| CoffeeIt's literally coffee | Other | The Turbo Sleepers |
| PlaceboIt's a placebo | Other | The Placebo Pouters |
Primary outcome
Post-Nap Grumpiness Score
Time frame: Exactly 90 seconds post-air horn blast.
Measured using the proprietary Grump-O-Meter Scale (0 to 10, where 0 is "delightful" and 10 is "don't look at me or I will quit").
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Jun 2026.
- Individual participant dataSharing planned: Undecided. Unsure at this time.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Coffee in people with Irritability, run by Hightower Clinical.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 9 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Brad P Guy in Charge (405-555-5555, brad@hightowerclinical.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Post-Nap Grumpiness Score (time frame: Exactly 90 seconds post-air horn blast.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jun 2026.