Emergency Department PatientsNCT07641400
Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea
An observational study of Emergency Department Patients and Pulmonary Hypertension, run by Antalya Health Sciences University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Emergency Department Patients, Pulmonary Hypertension, Pulmonary Embolism
- What is being tested?
- Pulmonary embolism (+) and pulmonary embolism (-)
- How many people
- 80 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jun 2026to 1 Oct 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients aged 18 and over who present to the emergency department with dyspnea between the specified study dates, are diagnosed with pulmonary embolism, have had their pulmonary artery pressure measured, have a previous pulmonary artery pressure measurement in their patient records, and have complete clinical, laboratory, imaging, and echocardiography data will be included in the study.
Who may be able to join
- Presenting to the emergency department with dyspnea between the specified dates,
- Being 18 years of age or older,
- Being evaluated in the emergency department with a preliminary diagnosis of pulmonary embolism,
- Having a recorded pulmonary artery pressure measurement at the time of hospital admission,
- Having a previous pulmonary artery pressure measurement in the patient's records,
- Having sufficient and complete clinical, laboratory, imaging, and echocardiography data available for the study.
Who cannot join
- Patients under 18 years of age,
- Lack of pulmonary artery pressure data from the time of emergency admission or from the previous period,
- Lack of necessary clinical, laboratory, or imaging data for pulmonary embolism evaluation,
- In cases of repeated admissions for the same patient, only the first suitable admission will be considered; other admissions will be excluded from the study,
- Patients whose data is unavailable in the record system or whose data is insufficient to be analyzed for research purposes.Inclusion Criteria for the Study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
University of Health Sciences, Antalya Training and Research Hospital
Antalya
About this study
Official title: The Diagnostic Value of The Difference Between Prior and Immediate Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea
The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.
Read the detailed description
Pulmonary embolism (PE) is a significant clinical condition requiring rapid diagnosis, with high mortality and morbidity, in patients presenting to the emergency department with shortness of breath. The chronic presence of dyspnea, particularly in individuals with chronic obstructive pulmonary disease (COPD), chronic heart failure, pulmonary hypertension, and similar cardiopulmonary diseases, makes it difficult to differentiate PE in the acute phase. In this patient group, pulmonary artery pressure (PAP) values measured by echocardiography can provide important clinical information in the diagnostic process. The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.
- Being tested
- Pulmonary embolism (+), pulmonary embolism (-)
- Keywords
- emergency deparment patients, pulmonary hypertension, pulmonary embolism, dispnea, chest pain
- Medical subject headings
- Hypertension, Pulmonary, Pulmonary Embolism, Chest Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pulmonary embolism (+)Other
patients diagnosed with pulmonary embolism who have previously had their pulmonary artery pressure measured
pulmonary embolism (-)Other
control group
| Study group | Role | What they receive |
|---|---|---|
| Pulmonary embolism (+) | Not described Receives: Other: Pulmonary embolism (+) | |
| Pulmonary embolism (-) | Not described Receives: Other: pulmonary embolism (-) |
What is being measured
The primary outcome is the main question the study is designed to answer.
pulmonary artery pressure
The difference between the pulmonary artery pressure measured in the previous echocardiogram and the pulmonary artery pressure at the time of admission to the emergency department.
Measured: 3 hours
Secondary outcomes (1)
the relationship between pulmonary embolism and comorbidity
The relationship between the degree of increase in pulmonary artery pressure and pulmonary embolism in patients with COPD and heart failure.
Measured: 3 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2026
- Study start1 Jun 2026 (estimated)
- Primary completion1 Sep 2026 (estimated)
- Study completion1 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Emergency Department PatientsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Antalya Health Sciences University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- MURAT DUYAN, ASSOCIATE PROFESSOR, Principal investigator, University of Health Sciences, Antalya Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07641400
- Sponsor's protocol ID
- 9/28
- Status last verified
- Jun 2026
- First submitted
- 1 Jun 2026
- Last updated
- 11 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Cao YQ, Dong LX, Cao J. Pulmonary Embolism in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Chin Med J (Engl). 2018 Jul 20;131(14):1732-1737. doi: 10.4103/0366-6999.235865.
PubMed 29998894
Study at a glance
From the registry record, last updated by the sponsor on 11 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Diagnostic Value of The Difference Between Prior and Immediate Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea
- ClinicalTrials.gov ID
- NCT07641400
- Acronym / sponsor ID
- 9/28
- Keywords
- emergency deparment patients, pulmonary hypertension, pulmonary embolism, dispnea, chest pain
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Antalya Health Sciences UniversityUniversity, hospital or other
- Study start
- 1 Jun 2026 (estimated)
- Primary completion
- 1 Sep 2026 (estimated)
- Study completion
- 1 Oct 2026 (estimated)
- First posted
- 11 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.
Detailed description
Pulmonary embolism (PE) is a significant clinical condition requiring rapid diagnosis, with high mortality and morbidity, in patients presenting to the emergency department with shortness of breath. The chronic presence of dyspnea, particularly in individuals with chronic obstructive pulmonary disease (COPD), chronic heart failure, pulmonary hypertension, and similar cardiopulmonary diseases, makes it difficult to differentiate PE in the acute phase. In this patient group, pulmonary artery pressure (PAP) values measured by echocardiography can provide important clinical information in the diagnostic process. The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Pulmonary embolism (+) | – | Other: Pulmonary embolism (+) |
| Pulmonary embolism (-) | – | Other: pulmonary embolism (-) |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients aged 18 and over who present to the emergency department with dyspnea between the specified study dates, are diagnosed with pulmonary embolism, have had their pulmonary artery pressure measured, have a previous pulmonary artery pressure measurement in their patient records, and have complete clinical, laboratory, imaging, and echocardiography data will be included in the study.
Key inclusion criteria (6 listed)
- Presenting to the emergency department with dyspnea between the specified dates,
- Being 18 years of age or older,
- Being evaluated in the emergency department with a preliminary diagnosis of pulmonary embolism,
- Having a recorded pulmonary artery pressure measurement at the time of hospital admission,
- Having a previous pulmonary artery pressure measurement in the patient's records,
Key exclusion criteria (5 listed)
- Patients under 18 years of age,
- Lack of pulmonary artery pressure data from the time of emergency admission or from the previous period,
- Lack of necessary clinical, laboratory, or imaging data for pulmonary embolism evaluation,
- In cases of repeated admissions for the same patient, only the first suitable admission will be considered; other admissions will be excluded from the study,
- Patients whose data is unavailable in the record system or whose data is insufficient to be analyzed for research purposes.Inclusion Criteria for the Study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pulmonary embolism (+)patients diagnosed with pulmonary embolism who have previously had their pulmonary artery pressure measured | Other | Pulmonary embolism (+) |
| pulmonary embolism (-)control group | Other | Pulmonary embolism (-) |
Primary outcome
pulmonary artery pressure
Time frame: 3 hours
The difference between the pulmonary artery pressure measured in the previous echocardiogram and the pulmonary artery pressure at the time of admission to the emergency department.
1 secondary outcome
the relationship between pulmonary embolism and comorbidity
Time frame: 3 hours
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Jun 2026.
- Results publication: PubMed 29998894Cao YQ, Dong LX, Cao J. Pulmonary Embolism in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Chin Med J (Engl). 2018 Jul 20;131(14):1732-1737. doi: 10.4103/0366-6999.235865.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
MURAT DUYAN, ASSOCIATE PROFESSOR principal investigator
University of Health Sciences, Antalya Training and Research Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Emergency Department Patients and Pulmonary Hypertension, run by Antalya Health Sciences University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 11 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact MURAT DUYAN, ASSOCIATE PROFESSOR (+905404120735, drmuratduyan@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
pulmonary artery pressure (time frame: 3 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07641400, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Jun 2026.