Comparison of Two Different Dual-Task Training Methods in Patients With Parkinson's Disease

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

• Ages 40 years and older
• All sexes
• No healthy volunteers
• Adult, Older adult

Trial locations and contacts

1 site in 1 country.

About this study

Official title: Comparison of Motor-Motor and Cognitive-Motor Dual-Task Training in Patients With Parkinson's Disease

Conditions

Parkinson's Disease (PD)

Being tested

Single Task Exercise Training, Motor-Motor Dual Task Exercise Training, Cognitive-Motor Dual Task Exercise Training

Keywords

Parkinson's Disease, Dual Task Training, Motor-Motor, Cognitive-Motor

Medical subject headings

Parkinson Disease

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

• Single Task Exercise TrainingOther

  Single task balance and walking exercises. 5-minute warm-up period, followed by 15 minutes of balance exercises and 15 minutes of walking exercises with a 5-minute rest in between, and then a 5-minute cool-down period.

• Motor-Motor Dual Task Exercise TrainingOther

  Motor-motor dual task balance and walking exercises. Motor-motor dual task balance and walking exercises. 5-minute warm-up period, followed by 15 minutes of balance exercises and 15 minutes of walking exercises concurrently performed with upper extremity motor tasks with a 5-minute rest in between, and then a 5-minute cool-down period.

• Cognitive-Motor Dual Task Exercise TrainingOther

  Cognitive-motor dual task balance and walking exercises. Cognitive-motor dual task balance and walking exercises. 5-minute warm-up period, followed by 15 minutes of balance exercises and 15 minutes of walking exercises concurrently performed with cognitive tasks with a 5-minute rest in between, and then a 5-minute cool-down period.

What is being measured

The primary outcome is the main question the study is designed to answer.

1. Unified Parkinson's Disease Rating Scale (UPDRS) - PART 3

   UPDRS is a reliable and valid scale that assesses cognitive skills, mood, daily living activities, motor skills, motor fluctuations, dyskinesias and autonomic dysfunction and is widely used in clinical studies and research in Parkinson's disease. The motor symptoms section, which is the third section of this scale, will be used.

   Measured: From enrollment to the end of training at 6 weeks

2. Hoehn & Yahr Scale

   It is a staging system that provides information quickly in determining the severity and symptoms of Parkinson's disease.

   Measured: From enrollment to the end of treatment at 6 weeks

3. Single-Leg Stance Test

   This is a test method used to assess static balance. The patient's preferred foot is raised without touching the supporting leg, and initially, the eyes are open. The eyes are fixed towards the head, and the patient is expected to maintain their balance for 60 seconds. The time the participant maintains their balance is recorded.

   Measured: From enrollment to the end of treatment at 6 weeks

4. Functional Reach Test

   This test is designed to assess dynamic balance. In the test, the participant is positioned sideways next to a wall, with their torso upright, the shoulder on the wall flexed to 90°, and the elbow fully extended. The participant is then asked to make a fist with the same arm, and the position of the third metacarpal head is marked on the wall. The participant reaches forward with their knees fully extended; the position of the third metacarpal head is marked again, and the participant returns to the starting position. The difference between the two marks is measured with a tape measure.

   Measured: From enrollment to the end of treatment at 6 weeks

5. 10 Meter Walking Test

   Participants are asked to walk at normal walking speed for a distance of 10 meters and the time is recorded.

   Measured: From enrollment to the end of treatment at 6 weeks

6. Motor-Motor Dual Task Cost of Walking

   To assess the motor-motor dual-task cost of walking, patients will perform the 10-meter walk test once as a single task and once while holding an empty plate on a tray in their hands. The dual-task cost will be calculated as a percentage using the following formula:

   [(Dual-task performance - Single-task performance)/ (Single-task performance) x 100]

   Measured: From enrollment to the end of treatment at 6 weeks

7. Cognitive-Motor Dual Task Cost of Walking

   To assess cognitive-motor dual-task cost of walking, patients will perform the 10-Meter Walk Test once as a single task and once as a dual-task test, counting backwards in increments of 7 from a three-digit number greater than 300. Dual-task cost will be calculated as a percentage using the following formula:

   [(Dual-task performance - Single-task performance)/ (Single-task performance) x 100]

   Measured: From enrollment to the end of treatment at 6 weeks

8. Timed Up and Go Test

   This test is used to assess functional mobility levels. The test involves using a standard chair with the individual's knees flexed at 90° and their backrest against it. The individual is asked to stand up from the chair, walk 3 meters, turn around, and then walk back to the chair and sit down. The test begins with the command "walk," and the test duration is measured with a stopwatch and recorded in seconds.

   Measured: From enrollment to the end of treatment at 6 weeks

9. Unified Parkinson's Disease Rating Scale (UPDRS) - PART 2

   It consists of thirteen items. The assessment is based on anamnesis information regarding how the patient functions in various activities. The presence of sensory complaints that may be related to tremor and parkinsonism is also included in this section as they can affect daily living activities. Each item is evaluated using a scoring system between '0' and '4'.

   Measured: From enrollment to the end of treatment at 6 weeks

10. Dual Task Questionnaire

    This test is used to assess the challenges encountered in daily tasks involving dual work. It consists of 10 questions and is administered via face-to-face interview. Each question is scored between 0 and 4. A score of "4" indicates frequent challenges, while a score of "0" indicates no challenges.

    Measured: From enrollment to the end of treatment at 6 weeks

11. Trail Making Test

    It is used to assess executive functions and attention. The test consists of two parts, A and B. In part A, the individual is asked to combine numbers from 1 to 25, and the completion time is recorded. In part B, the individual completes a sequence where each number corresponds to a letter, and the completion time is recorded.

    Measured: From enrollment to the end of treatment at 6 weeks

12. Activity-Specific Balance Confidence Scale

    This is a commonly used scale for assessing balance confidence. The scale evaluates whether individuals believe they can perform daily living activities without losing their balance or becoming unsteady. It consists of sixteen items. Each item is scored between a minimum of "0" (unconfident) and a maximum of "100" (completely confident). The base score is calculated by dividing the total score by 16. Higher values indicate that the person feels good about their balance, while lower values are associated with an increased risk of falls.

    Measured: From enrollment to the end of treatment at 6 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1. First posted11 Jun 2026
2. Study start15 Jun 2026
3. Primary completion16 Oct 2026
4. Study completion16 Oct 2026

Resources

• Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
• Other trials for Parkinson's Disease (PD)Studies of the same condition, open and under way.
• What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.