Apical Termination PointNCT07642349
Effect of Different Apical Termination Point Guided by Electronic Apex Locator on Post Endodontic Pain , A Randomized Control Trial.
A study testing apical constriction and length determintion in people with Apical Termination Point, run by Prof Nazeer Khan at 1 site in Pakistan.
Trial summary
This randomized control trial compares the different apical termination point by using electronic apex locator J morita root ZX on post endodontic pain patient with single rooted teeth will be randomly assigned in to three groups according to sample size and reading of electronic apex locator having two experimental… Read more about this study
- Who is it for?
- Ages 20 to 50 daysHealthy volunteers can take part
- Conditions the study is for
- Apical Termination Point
- What is being tested?
- apical constriction and length determintion
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 125 participants
- Where
- 1 sitePakistan
- Study dates
- 4 Apr 2026to 21 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 50 days
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- Mature Permanent teeth with closed apex
- Single rooted teeth
- Symptomatic irreversible pulpitis with normal apex
- Systemic healthy patient ASA I and ASA II
- Gender male and female
- Age: 20 to 50 years
Show all 10Show fewer
- 5. Exclusion Criteria:
- Bizarre morphology
- Teeth with open apices
- Pathological root resorption
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country.
About this study
This randomized control trial compares the different apical termination point by using electronic apex locator J morita root ZX on post endodontic pain patient with single rooted teeth will be randomly assigned in to three groups according to sample size and reading of electronic apex locator having two experimental group and one control group included radiographic method following inclusion criteria .
after following the clinical steps in two visit root canal treatment, pain was asses on VAS from day 1 to day 3 before obturation and percussion test was also asses either positive or negative.
- Conditions
- Apical Termination Point
- Being tested
- apical constriction and length determintion
- Keywords
- apical termination point root canal trteatment
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
apical constriction and length determintionDevice
This randomized control trial compares the different apical termination point by using electronic apex locator J morita root ZX on post endodontic pain patient with single rooted teeth will be randomly assigned in to three groups according to sample size and reading of electronic apex locator having two experimental group and one control group included radiographic method following inclusion criteria .
after following the clinical steps in two visit root canal treatment, pain was asses on VAS from day 1 to day 3 before obturation and percussion test was also asses either positive or negative.
| Study group | Role | What they receive |
|---|---|---|
| effect of different apical termination point guided by electronic apex locator on post endodontic pa | Experimental | Not described Receives: Device: apical constriction and length determintion |
What is being measured
The primary outcome is the main question the study is designed to answer.
post endodontic pain in VAS
This randomized control trial compares the different apical termination point by using electronic apex locator J morita root ZX on post endodontic pain patient with single rooted teeth will be randomly assigned in to three groups according to sample size and reading of electronic apex locator having two experimental group and one control group included radiographic method following inclusion criteria .
after following the clinical steps in two visit root canal treatment, pain was asses on VAS from day 1 to day 3 before obturation and percussion test was also asses either positive or negative.
Measured: 3 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2026
- Study start4 Apr 2026
- Primary completion14 May 2026
- Study completion21 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Apical Termination PointStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 125 participants (actual)
Sponsor and investigators
- Lead sponsor
- Prof Nazeer Khan
- Sponsor type
- University, hospital or other
- Collaborators
- Baqai Medical University
- Responsible party
- Sponsor-investigator, Prof Nazeer Khan, Baqai Medical University
- Investigators
- misbah muhammad saleem, MDS, Principal investigator, Baqai Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07642349
- Sponsor's protocol ID
- MDS- MISBAH MUHAMMAD SALEEM
- Status last verified
- Jun 2025
- First submitted
- 8 Jun 2026
- Last updated
- 11 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Different Apical Termination Point Guided by Electronic Apex Locator on Post Endodontic Pain , A Randomized Control Trial.
- ClinicalTrials.gov ID
- NCT07642349
- Acronym / sponsor ID
- MDS- MISBAH MUHAMMAD SALEEM
- Conditions
- Apical Termination Point
- Keywords
- apical termination point root canal trteatment
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 125 participants (actual)
- Lead sponsor
- Prof Nazeer KhanUniversity, hospital or other
- Collaborators
- Baqai Medical University
- Study start
- 4 Apr 2026 (actual)
- Primary completion
- 14 May 2026 (actual)
- Study completion
- 21 May 2026 (actual)
- First posted
- 11 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized control trial compares the different apical termination point by using electronic apex locator J morita root ZX on post endodontic pain patient with single rooted teeth will be randomly assigned in to three groups according to sample size and reading of electronic apex locator having two experimental group and one control group included radiographic method following inclusion criteria .
after following the clinical steps in two visit root canal treatment, pain was asses on VAS from day 1 to day 3 before obturation and percussion test was also asses either positive or negative.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| effect of different apical termination point guided by electronic apex locator on post endodontic pa | Experimental | Device: apical constriction and length determintion |
Who may qualify
- Ages
- 20 to 50 days
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (10 listed)
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| apical constriction and length determintionThis randomized control trial compares the different apical termination point by using electronic apex locator J morita root ZX on post endodontic pain patient with single rooted teeth will be randomly assigned in to three groups according to sample size and reading of electronic apex locator having two experimental group and one control group included radiographic method following inclusion criteria . after following the clinical steps in two visit root canal treatment, pain was asses on VAS from day 1 to day 3 before obturation and percussion test was also asses either positive or negative. | Device | effect of different apical termination point guided by electronic apex locator on post endodontic pa |
Primary outcome
post endodontic pain in VAS
Time frame: 3 days
This randomized control trial compares the different apical termination point by using electronic apex locator J morita root ZX on post endodontic pain patient with single rooted teeth will be randomly assigned in to three groups according to sample size and reading of electronic apex locator having two experimental group and one control group included radiographic method following inclusion criteria . after following the clinical steps in two visit root canal treatment, pain was asses on VAS from day 1 to day 3 before obturation and percussion test was also asses either positive or negative.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Jun 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
misbah muhammad saleem, MDS principal investigator
Baqai Medical University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing apical constriction and length determintion in people with Apical Termination Point, run by Prof Nazeer Khan at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 10 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
post endodontic pain in VAS (time frame: 3 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Jun 2026.