Burn InjuryMito BurnNCT07643545
Mitochondrial Energy Metabolism in Burns
An observational study of Burn Injury, run by Arkansas Children's Hospital Research Institute at 1 site in United States.
Trial summary
The goal of this observational study is to assess the impact of burn injury on cellular energetics in patients that have been admitted to the burn center at Arkansas Children's Hospital for burn care and require one or more procedures to clean, debride, and repair burn wounds will be eligible to participate in this… Read more about this study
- Who is it for?
- Ages 2 to 80 years
- Conditions the study is for
- Burn Injury
- How many people
- 125 participants
- Where
- 1 siteUnited States
- Study dates
- 20 Apr 2023to Jun 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 2 to 80 years
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Up to 125 patients (2 years to 80 years old) will be enrolled in this study. We will recruit both males and females requiring hospital admission to the ACH burn unit for burn care.
Who may be able to join
- Male or Female
- Ages 2 years to 80 years
- Requiring hospital admission for burn care
- All races
- All ethnicities
Who cannot join
- Age < 2 years
- Under 10 kg in body mass
- Age > 80 years
- Active pregnancy
- Unable to provide informed consent and no legal authorized representative present
- Patient is considered moribund at the time of admission by the treating physician.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Arkansas Children's Hospital
Little Rock, Arkansas, 72202
Craig Porter, PhD
Esther Teo, MD
About this study
Official title: The Role of the Mitochondrian in the Metabolic Stress Response to Burn Trauma
The goal of this observational study is to assess the impact of burn injury on cellular energetics in patients that have been admitted to the burn center at Arkansas Children's Hospital for burn care and require one or more procedures to clean, debride, and repair burn wounds will be eligible to participate in this study.
During the study, we will collect the following information:
- General background information such as date of birth, height, weight, and other basic information.
- Medical information, such as: basic medical information, details of burn injury, vital signs on the day of surgery, medicines you take during your stay, and some clinical tests.
- Blood, urine, and tissue during surgeries you have during your stay.
- Conditions
- Burn Injury
- Medical subject headings
- Burns
What is being measured
The primary outcome is the main question the study is designed to answer.
Blood Bioenergetics
Peripheral Blood Mononuclear Cell (PBMC) respiration
Measured: Through study completion, an average of 1 year
Secondary outcomes (1)
Blood metabolics signatures
Peripheral Blood Mononuclear Cell (PBMC) respiration
Measured: Through study completion, an average of 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2026
- Study start20 Apr 2023
- Primary completionJun 2026 (estimated)
- Study completionJun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Burn InjuryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 125 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Arkansas Children's Hospital Research Institute
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute of General Medical Sciences (NIGMS)
- Responsible party
- Sponsor
- Investigators
- Craig Porter, PhD, Principal investigator, Arkansas Children's Research Institute
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07643545
- Sponsor's protocol ID
- 263136
- Acronym
- Mito Burn
- Status last verified
- Jun 2026
- First submitted
- 10 Aug 2023
- Last updated
- 11 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Role of the Mitochondrian in the Metabolic Stress Response to Burn Trauma
- ClinicalTrials.gov ID
- NCT07643545
- Acronym / sponsor ID
- Mito Burn / 263136
- Conditions
- Burn Injury
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 125 participants (estimated)
- Lead sponsor
- Arkansas Children's Hospital Research InstituteUniversity, hospital or other
- Collaborators
- National Institute of General Medical Sciences (NIGMS)
- Study start
- 20 Apr 2023 (actual)
- Primary completion
- Jun 2026 (estimated)
- Study completion
- Jun 2026 (estimated)
- First posted
- 11 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to assess the impact of burn injury on cellular energetics in patients that have been admitted to the burn center at Arkansas Children's Hospital for burn care and require one or more procedures to clean, debride, and repair burn wounds will be eligible to participate in this study.
During the study, we will collect the following information:
- General background information such as date of birth, height, weight, and other basic information.
- Medical information, such as: basic medical information, details of burn injury, vital signs on the day of surgery, medicines you take during your stay, and some clinical tests.
- Blood, urine, and tissue during surgeries you have during your stay.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 2 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Up to 125 patients (2 years to 80 years old) will be enrolled in this study. We will recruit both males and females requiring hospital admission to the ACH burn unit for burn care.
Key inclusion criteria (5 listed)
- Male or Female
- Ages 2 years to 80 years
- Requiring hospital admission for burn care
- All races
- All ethnicities
Key exclusion criteria (6 listed)
- Age < 2 years
- Under 10 kg in body mass
- Age > 80 years
- Active pregnancy
- Unable to provide informed consent and no legal authorized representative present
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Blood Bioenergetics
Time frame: Through study completion, an average of 1 year
Peripheral Blood Mononuclear Cell (PBMC) respiration
1 secondary outcome
Blood metabolics signatures
Time frame: Through study completion, an average of 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Craig Porter, PhD principal investigator
Arkansas Children's Research Institute
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Burn Injury, run by Arkansas Children's Hospital Research Institute at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 11 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Craig Porter, PhD (5013643340, cporter@uams.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Blood Bioenergetics (time frame: Through study completion, an average of 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Jun 2026.