Intellectual Disability, Mild to ModerateAMRLENCT07647926
Adaptive Mixed Reality for Students With Intellectual Disabilities
A study testing Adaptive Mixed Reality Learning Environment (AMRLE) in people with Intellectual Disability, Mild to Moderate, run by King Salman Center for Disability Research at 1 site in Egypt.
Trial summary
This study design investigates the empirical efficacy of an Adaptive Mixed Reality Learning Environment (AMRLE) tailored for educable adolescents and young adults (aged 10-20) diagnosed with mild-to-moderate intellectual disabilities in Jeddah, Saudi Arabia. Read more about this study
- Who is it for?
- Ages 10 to 20 years
- Conditions the study is for
- Intellectual Disability, Mild to Moderate
- What is being tested?
- Adaptive Mixed Reality Learning Environment (AMRLE)
- Type of treatment
- Pill or oral medicine, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 44 participants
- Where
- 1 siteEgypt
- Study dates
- 11 Jan 2026to 12 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 20 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- Enrolled in certified special education centers or inclusive schools in Jeddah, Saudi Arabia.
- Chronological age between 10.0 and 20.0 years.
- Official clinical diagnosis of mild-to-moderate intellectual disability based on DSM-5 criteria.
- IQ score ranging between 50 and 69, measured via standardized Arabic versions of Stanford-Binet or WISC-V scales calibrated for the Saudi population.
- Classified under the Saudi educational framework as "Educable Intellectual Disability," displaying basic functional communication and the ability to follow two-step verbal commands.
- Normal or corrected-to-normal vision and hearing, with manual dexterity to interact with objects.
Who cannot join
- Co-occurring severe neurodevelopmental conditions (e.g., profound Autism Spectrum Disorder with severe self-injurious or aggressive behavioral manifestations).
- Documented medical history of photosensitive epilepsy or severe vestibulo-ocular reflex disorders triggered by digital or stereoscopic displays.
- Total absence of functional verbal comprehension in Arabic.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Mixed Reality Adaptive Learning Environments for Improving the Digital Quality of Life of Students With Intellectual Disabilities
This study design investigates the empirical efficacy of an Adaptive Mixed Reality Learning Environment (AMRLE) tailored for educable adolescents and young adults (aged 10-20) diagnosed with mild-to-moderate intellectual disabilities in Jeddah, Saudi Arabia. Standard digital user interfaces often impose heavy cognitive taxes on neurodivergent learners, generating a operational digital divide that limits their independence. To address this issue, an intelligent application was developed to track behavioral metrics, including response latency and error frequency, dynamically delivery sensory scaffolding, visual pruning, and localized Arabic auditory guidance. The primary purpose is to systematically evaluate the clinical-pedagogical impact of this dynamic spat…
- Being tested
- Adaptive Mixed Reality Learning Environment (AMRLE)
- Keywords
- Mixed Reality, Digital Quality of Life, Adaptive Learning, Spatial Computing
- Medical subject headings
- Intellectual Disability
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Adaptive Mixed Reality Learning Environment (AMRLE)Behavioural
An interactive 3D spatial computing application configured with an adaptivity engine. It continuously processes response latency and error frequencies to deliver visual pruning, multi-sensory concrete-to-abstract micro-scaffolding, and Arabic audio prompts tailored for learning digital autonomy and safety.
| Study group | Role | What they receive |
|---|---|---|
| Experimental: Adaptive Mixed Reality | Experimental | Participants interact with an Adaptive Mixed Reality Learning Environment (AMRLE) via standalone headsets. The system tracks dynamic telemetry (response latency and error frequency) to deliver automated micro-scaffolding, visual pruning, and Arabic auditory cues to enhance digital quality of life. Receives: Behavioral: Adaptive Mixed Reality Learning Environment (AMRLE) |
| Active Control: Conventional Interface | Active comparator | Participants target identical learning domains and modules using a conventional, non-adaptive touch-screen tablet interface within the same resource room environmental settings. Receives: Behavioral: Adaptive Mixed Reality Learning Environment (AMRLE) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Digital Quality of Life Observation Scale (DQoLOS)
A 16-item standardized behavioral observation instrument designed to evaluate the multidimensional constructs of digital quality of life across four primary subscales: digital autonomy, digital safety, digital well-being, and social inclusion. Each item is scored on a 3-point Likert configuration (3 = Consistently/Autonomous, 2 = Intermittently/Assisted, 1 = Rarely/Dependent). Total scores range from a minimum of 16 to a maximum of 48, with higher values representing superior digital adaptation and independent technological quality of life.
Measured: Change from baseline (pre-intervention) at Week 0 to post-intervention outcomes at Week 8.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jun 2026
- Study start11 Jan 2026
- Primary completion25 Apr 2026
- Study completion12 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Intellectual Disability, Mild to ModerateStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 44 participants (actual)
Sponsor and investigators
- Lead sponsor
- King Salman Center for Disability Research
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Abdellah Ibrahim Mohammed Elfeky, King Salman Center for Disability Research
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07647926
- Sponsor's protocol ID
- KSRG-2026-053
- Acronym
- AMRLE
- Status last verified
- Jun 2026
- First submitted
- 2 Jun 2026
- Last updated
- 15 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Mixed Reality Adaptive Learning Environments for Improving the Digital Quality of Life of Students With Intellectual Disabilities
- ClinicalTrials.gov ID
- NCT07647926
- Acronym / sponsor ID
- AMRLE / KSRG-2026-053
- Keywords
- Mixed Reality, Digital Quality of Life, Adaptive Learning, Spatial Computing
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 44 participants (actual)
- Lead sponsor
- King Salman Center for Disability ResearchUniversity, hospital or other
- Study start
- 11 Jan 2026 (actual)
- Primary completion
- 25 Apr 2026 (actual)
- Study completion
- 12 May 2026 (actual)
- First posted
- 15 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study design investigates the empirical efficacy of an Adaptive Mixed Reality Learning Environment (AMRLE) tailored for educable adolescents and young adults (aged 10-20) diagnosed with mild-to-moderate intellectual disabilities in Jeddah, Saudi Arabia. Standard digital user interfaces often impose heavy cognitive taxes on neurodivergent learners, generating a operational digital divide that limits their independence. To address this issue, an intelligent application was developed to track behavioral metrics, including response latency and error frequency, dynamically delivery sensory scaffolding, visual pruning, and localized Arabic auditory guidance. The primary purpose is to systematically evaluate the clinical-pedagogical impact of this dynamic spat…
Study design
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimental: Adaptive Mixed Reality | Experimental | Behavioral: Adaptive Mixed Reality Learning Environment (AMRLE)Participants interact with an Adaptive Mixed Reality Learning Environment (AMRLE) via standalone headsets. The system tracks dynamic telemetry (response latency and error frequency) to deliver automated micro-scaffolding, visual pruning, and Arabic auditory cues to enhance digital quality of life. |
| Active Control: Conventional Interface | Active comparator | Behavioral: Adaptive Mixed Reality Learning Environment (AMRLE)Participants target identical learning domains and modules using a conventional, non-adaptive touch-screen tablet interface within the same resource room environmental settings. |
Who may qualify
- Ages
- 10 to 20 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (6 listed)
- Enrolled in certified special education centers or inclusive schools in Jeddah, Saudi Arabia.
- Chronological age between 10.0 and 20.0 years.
- Official clinical diagnosis of mild-to-moderate intellectual disability based on DSM-5 criteria.
- IQ score ranging between 50 and 69, measured via standardized Arabic versions of Stanford-Binet or WISC-V scales calibrated for the Saudi population.
- Classified under the Saudi educational framework as "Educable Intellectual Disability," displaying basic functional communication and the ability to follow two-step verbal commands.
Key exclusion criteria (3 listed)
- Co-occurring severe neurodevelopmental conditions (e.g., profound Autism Spectrum Disorder with severe self-injurious or aggressive behavioral manifestations).
- Documented medical history of photosensitive epilepsy or severe vestibulo-ocular reflex disorders triggered by digital or stereoscopic displays.
- Total absence of functional verbal comprehension in Arabic.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Adaptive Mixed Reality Learning Environment (AMRLE)An interactive 3D spatial computing application configured with an adaptivity engine. It continuously processes response latency and error frequencies to deliver visual pruning, multi-sensory concrete-to-abstract micro-scaffolding, and Arabic audio prompts tailored for learning digital autonomy and safety. | Behavioural | Active Control: Conventional Interface, Experimental: Adaptive Mixed Reality |
Primary outcome
Digital Quality of Life Observation Scale (DQoLOS)
Time frame: Change from baseline (pre-intervention) at Week 0 to post-intervention outcomes at Week 8.
A 16-item standardized behavioral observation instrument designed to evaluate the multidimensional constructs of digital quality of life across four primary subscales: digital autonomy, digital safety, digital well-being, and social inclusion. Each item is scored on a 3-point Likert configuration (3 = Consistently/Autonomous, 2 = Intermittently/Assisted, 1 = Rarely/Dependent). Total scores range from a minimum of 16 to a maximum of 48, with higher values representing superior digital adaptation and independent technological quality of life.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Adaptive Mixed Reality Learning Environment (AMRLE) in people with Intellectual Disability, Mild to Moderate, run by King Salman Center for Disability Research at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Digital Quality of Life Observation Scale (DQoLOS) (time frame: Change from baseline (pre-intervention) at Week 0 to post-intervention outcomes at Week 8.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jun 2026.