Altered Passive Eruption of TeethNCT07649226
Laser-Assisted Minimally Invasive Esthetic Crown Lengthening Using Flapless vs. Tunneled Flap Approach
A study testing laser assissted crown lengthening, surgical esthetic crown lengthening and Laser-assisted tunneled flap approach in people with Altered Passive Eruption of Teeth, run by Alexandria University at 1 site in Egypt.
Trial summary
Crown lengthening surgery is one of the most commonly performed periodontal procedures. Multiple techniques have been used throughout the years to overcome the postoperative pain and adverse outcomes that may be associated with surgical crown lengthening. Read more about this study
- Who is it for?
- Ages 21 years and older
- Conditions the study is for
- Altered Passive Eruption of Teeth
- What is being tested?
- laser assissted crown lengthening, surgical esthetic crown lengthening and Laser-assisted tunneled flap approach
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteEgypt
- Study dates
- 30 Mar 2026to Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients with an excessive gingival display of at least 3 mm
- Age >21 years
- At least six anterior maxillary teeth requiring ECL
- Healthy periodontal status, indicated by a full-mouth plaque index and bleeding on probing index scores of <15%.
- Patients with thick gingival phenotype
Who cannot join
- Treatment sites with probing depths more than 3 mm
- Patients with a history of smoking
- Patients with a history of mucogingival surgery in the intended treatment area
- Systemic conditions that could hinder tissue healing (e.g., uncontrolled diabetes and autoimmune diseases)
- Patients undergoing active orthodontic treatment
- Presence of any cause of excessive gingival display other than altered passive eruption
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Laser-Assisted Minimally Invasive Esthetic Crown Lengthening Using Flapless vs. Tunneled Flap Approach (Randomized Controlled Clinical Trial)
Crown lengthening surgery is one of the most commonly performed periodontal procedures. Multiple techniques have been used throughout the years to overcome the postoperative pain and adverse outcomes that may be associated with surgical crown lengthening. One of the most popular choices among clinicians is using different types of lasers in different techniques to overcome those adverse effects. Treatment effectiveness can be monitored non-invasively through salivary levels of Leukocyte Esterase enzyme and the stability clinical outcomes.
- Conditions
- Altered Passive Eruption of Teeth
- Being tested
- laser assissted crown lengthening, surgical esthetic crown lengthening, Laser-assisted tunneled flap approach
- Keywords
- altered passive eruption, periodontology, leukocyte esterase, esthetic crown lengthening
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
laser assissted crown lengtheningProcedure or surgery
laser-assissted flapless crown lengthening and laser-assissted tunneled flap approach
surgical esthetic crown lengtheningProcedure or surgery
surgical crown lengthening using scalpels and rotary instruments.
Laser-assisted tunneled flap approachProcedure or surgery
In this approach, the gingival margin will be tunneled to provide visibility for the operator during bone removal using laser.
| Study group | Role | What they receive |
|---|---|---|
| conventional surgical crown lenhthening | Active comparator | gold standard of treatment Receives: Procedure: surgical esthetic crown lengthening |
| Laser assissted flapless approach | Active comparator | Not described Receives: Procedure: laser assissted crown lengthening |
| Tunneled flap approach | Active comparator | Not described Receives: Procedure: Laser-assisted tunneled flap approach |
What is being measured
The primary outcome is the main question the study is designed to answer.
leukocyte esterase enzyme assessment using Periomonitor
Periomonitor strips will be used to detect the amount of leukocyte esterase enzyme in saliva
Measured: 1 month
Clinical outcome stability
Clinical outcome stability will be assessed by measuring the length of the crown and interdental papillae immediately postoperatively, 1 week postoperatively, 1 month postoperatively, 3 months postoperatively and 6 months postoperatively.
Measured: 6 months
PROM
Binary questionnaire (Yes/No) questions will be asked.
Measured: 1 week
Secondary outcomes (1)
Marginal bone loss evaluated using CBCT
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jun 2026
- Study start30 Mar 2026
- Primary completionJun 2026 (estimated)
- Study completionSep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Altered Passive Eruption of TeethStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Alexandria University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07649226
- Sponsor's protocol ID
- 9296348
- Status last verified
- Mar 2026
- First submitted
- 4 Jun 2026
- Last updated
- 16 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Laser-Assisted Minimally Invasive Esthetic Crown Lengthening Using Flapless vs. Tunneled Flap Approach (Randomized Controlled Clinical Trial)
- ClinicalTrials.gov ID
- NCT07649226
- Acronym / sponsor ID
- 9296348
- Conditions
- Altered Passive Eruption of Teeth
- Keywords
- altered passive eruption, periodontology, leukocyte esterase, esthetic crown lengthening
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 45 participants (estimated)
- Lead sponsor
- Alexandria UniversityUniversity, hospital or other
- Study start
- 30 Mar 2026 (actual)
- Primary completion
- Jun 2026 (estimated)
- Study completion
- Sep 2026 (estimated)
- First posted
- 16 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Crown lengthening surgery is one of the most commonly performed periodontal procedures. Multiple techniques have been used throughout the years to overcome the postoperative pain and adverse outcomes that may be associated with surgical crown lengthening. One of the most popular choices among clinicians is using different types of lasers in different techniques to overcome those adverse effects. Treatment effectiveness can be monitored non-invasively through salivary levels of Leukocyte Esterase enzyme and the stability clinical outcomes.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| conventional surgical crown lenhthening | Active comparator | Procedure: surgical esthetic crown lengtheninggold standard of treatment |
| Laser assissted flapless approach | Active comparator | Procedure: laser assissted crown lengthening |
| Tunneled flap approach | Active comparator | Procedure: Laser-assisted tunneled flap approach |
Who may qualify
- Ages
- 21 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Patients with an excessive gingival display of at least 3 mm
- Age >21 years
- At least six anterior maxillary teeth requiring ECL
- Healthy periodontal status, indicated by a full-mouth plaque index and bleeding on probing index scores of <15%.
- Patients with thick gingival phenotype
Key exclusion criteria (6 listed)
- Treatment sites with probing depths more than 3 mm
- Patients with a history of smoking
- Patients with a history of mucogingival surgery in the intended treatment area
- Systemic conditions that could hinder tissue healing (e.g., uncontrolled diabetes and autoimmune diseases)
- Patients undergoing active orthodontic treatment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| laser assissted crown lengtheninglaser-assissted flapless crown lengthening and laser-assissted tunneled flap approach | Procedure or surgery | Laser assissted flapless approach |
| surgical esthetic crown lengtheningsurgical crown lengthening using scalpels and rotary instruments. | Procedure or surgery | conventional surgical crown lenhthening |
| Laser-assisted tunneled flap approachIn this approach, the gingival margin will be tunneled to provide visibility for the operator during bone removal using laser. | Procedure or surgery | Tunneled flap approach |
Primary outcome
leukocyte esterase enzyme assessment using Periomonitor
Time frame: 1 month
Periomonitor strips will be used to detect the amount of leukocyte esterase enzyme in saliva
Clinical outcome stability
Time frame: 6 months
Clinical outcome stability will be assessed by measuring the length of the crown and interdental papillae immediately postoperatively, 1 week postoperatively, 1 month postoperatively, 3 months postoperatively and 6 months postoperatively.
PROM
Time frame: 1 week
Binary questionnaire (Yes/No) questions will be asked.
1 secondary outcome
Marginal bone loss evaluated using CBCT
Time frame: 6 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jun 2026.
- Individual participant dataSharing planned: No
Related trials for Altered Passive Eruption of Teeth
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Altered Passive Eruption of Teeth
Active, not recruiting
Clinical Evaluation of Gingivalstat Approach Compared to Conventional Esthetic Crown Lengthening on the Stability of The Gingival Margin in Patients With Altered Passive Eruption.
Gummy Smile, Altered Passive Eruption of Teeth
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing laser assissted crown lengthening, surgical esthetic crown lengthening and Laser-assisted tunneled flap approach in people with Altered Passive Eruption of Teeth, run by Alexandria University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 16 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
leukocyte esterase enzyme assessment using Periomonitor (time frame: 1 month). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jun 2026.