HealthyNCT07649785
Static Stretching Reshapes Post-RT Recovery
A study testing Resistance Training and Resistance training + Static Stretching in people with Healthy and Healthy Subjects (HS), run by University of Palermo at 1 site in Italy.
Trial summary
This experimental study investigates the acute cardiovascular and local recovery to a single session of resistance training, with and without additional static stretching, compared with a resting control condition. Read more about this study
- Who is it for?
- Ages 18 to 55 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Healthy, Healthy Subjects (HS), Cardiovascular Adaption
- What is being tested?
- Resistance Training and Resistance training + Static Stretching
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 28 participants
- Where
- 1 siteItaly
- Study dates
- 12 Jan 2026to 10 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- healthy male participants ≥ 18 years old
Who cannot join
- orthopedic disorders
- neurological disorders
- metabolic disorders
- cardovascular disorders
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Hemodynamic Load and Local Recovery Patterns After Resistance Training With and Without Static Stretching
This experimental study investigates the acute cardiovascular and local recovery to a single session of resistance training, with and without additional static stretching, compared with a resting control condition. Participants are allocated to one of three groups (control, resistance training, resistance training plus static stretching) and assessed at baseline, immediately after the session, and 30 minutes post-exercise. Primary outcomes include rate-pressure product and local muscle oxygen saturation, while secondary outcomes include heart rate, blood pressure, brachial artery diameter, tissue hardness, and pressure pain threshold. These measures are used to characterize the short-term effects of the different experimental conditions on systemic hemodynamic load, vascular response, local muscle oxygenation, mechanical tissue status, and pressure pain sensitivity during early recovery.
- Being tested
- Resistance Training, Resistance training + Static Stretching
- Keywords
- stretching, static stretching, recovery, resistance training, oxygenation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Resistance TrainingOther
Participants assigned to this group will complete a single supervised upper body resistance training session. The protocol includes bench presses and bicep curls performed at 100% of the individual's 8-rep max, for 4 sets of 8 reps, with standardized rest intervals between sets of 2 minutes. The total duration of the session is approximately 20-25 minutes and does not include any additional static stretching beyond the standardized warm-up.
Resistance training + Static StretchingOther
Participants assigned to this group will complete a single supervised upper body resistance training session. The protocol includes bench presses and bicep curls performed at 100% of the individual's 8-rep max, for 4 sets of 8 reps, with standardized rest intervals between sets of 2 minutes. The total duration of the session is approximately 20-25 minutes .Immediately after the resistance exercises, they will complete a structured static stretching protocol targeting the trained muscle groups (pectoralis and elbow flexor), with each stretch held for about 30 seconds and repeated for several sets. The additional stretching lasts 12 minutes, for a total session duration of about 30-35 minutes.
| Study group | Role | What they receive |
|---|---|---|
| RT | Experimental | Resistance Training Receives: Other: Resistance Training |
| RT+SS | Experimental | Resistance Training + Static Stretching Receives: Other: Resistance training + Static Stretching |
| Control Condition(CC) | No intervention | participants sat silently on a chair without performing any train |
What is being measured
The primary outcome is the main question the study is designed to answer.
Rate-Pressure Product (RPP)
Rate-pressure product (RPP) will be used as an index of myocardial workload and hemodynamic load during early post-exercise recovery. RPP will be calculated as heart rate multiplied by systolic blood pressure (Omron MX3 Plus). Heart rate and systolic blood pressure will be measured under standardized resting conditions at each time point.
Measured: 3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)
Local Muscle Oxygen Saturation (SmO₂)
Local muscle oxygen saturation (SmO₂) will be assessed using near-infrared spectroscopy (Moxy Monitor). The sensor will be positioned over the target muscle region and secured to minimize movement artifacts. SmO₂ will be recorded as a local index of the balance between oxygen delivery and oxygen utilization within the sampled muscle region.
Measured: Time Frame: 3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)
Secondary outcomes (3)
Brachial Artery diameter
Brachial artery diameter will be assessed using high-resolution B-mode ultrasound (Esaote MyLab X1 GO, linear-array transducer). The brachial artery will be imaged under standardized conditions, and arterial diameter will be measured at each time point to assess acute changes in conduit artery size during early post-exercise recovery.
Measured: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
Tissue Hardness (TH)
Tissue hardness (TH) will be assessed using a tissue hardness meter/force gauge (Neutone) at selected muscle sites involved in the exercise protocol, including the pectoral and biceps regions. Measurements will be performed under standardized participant positioning and probe placement conditions. TH will be used as a local mechanical marker of the post-exercise tissue response.
Measured: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
Pain pressure Threshold(PPT)
Pressure pain threshold (PPT) will be assessed using a pressure algometer(WAGNER, FPX) at selected muscle sites involved in the exercise protocol. The algometer will be applied perpendicular to the skin surface with gradually increasing pressure until the participant reports the first sensation of pain. PPT will be used as a sensory marker of local pressure pain sensitivity during early recovery.
Measured: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jun 2026
- Study start12 Jan 2026
- Primary completion10 Mar 2026
- Study completion10 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 28 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Palermo
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ewan Thomas, University of Palermo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07649785
- Sponsor's protocol ID
- 353/2025 SS
- Status last verified
- Jun 2026
- First submitted
- 10 Jun 2026
- Last updated
- 16 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Hemodynamic Load and Local Recovery Patterns After Resistance Training With and Without Static Stretching
- ClinicalTrials.gov ID
- NCT07649785
- Acronym / sponsor ID
- 353/2025 SS
- Keywords
- stretching, static stretching, recovery, resistance training, oxygenation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 28 participants (actual)
- Lead sponsor
- University of PalermoUniversity, hospital or other
- Study start
- 12 Jan 2026 (actual)
- Primary completion
- 10 Mar 2026 (actual)
- Study completion
- 10 Mar 2026 (actual)
- First posted
- 16 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This experimental study investigates the acute cardiovascular and local recovery to a single session of resistance training, with and without additional static stretching, compared with a resting control condition. Participants are allocated to one of three groups (control, resistance training, resistance training plus static stretching) and assessed at baseline, immediately after the session, and 30 minutes post-exercise. Primary outcomes include rate-pressure product and local muscle oxygen saturation, while secondary outcomes include heart rate, blood pressure, brachial artery diameter, tissue hardness, and pressure pain threshold. These measures are used to characterize the short-term effects of the different experimental conditions on systemic hemodynamic load, vascular response, local muscle oxygenation, mechanical tissue status, and pressure pain sensitivity during early recovery.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| RT | Experimental | Other: Resistance TrainingResistance Training |
| RT+SS | Experimental | Other: Resistance training + Static StretchingResistance Training + Static Stretching |
| Control Condition(CC) | No intervention | –participants sat silently on a chair without performing any train |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- healthy male participants ≥ 18 years old
Key exclusion criteria (4 listed)
- orthopedic disorders
- neurological disorders
- metabolic disorders
- cardovascular disorders
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Resistance TrainingParticipants assigned to this group will complete a single supervised upper body resistance training session. The protocol includes bench presses and bicep curls performed at 100% of the individual's 8-rep max, for 4 sets of 8 reps, with standardized rest intervals between sets of 2 minutes. The total duration of the session is approximately 20-25 minutes and does not include any additional static stretching beyond the standardized warm-up. | Other | RT |
| Resistance training + Static StretchingParticipants assigned to this group will complete a single supervised upper body resistance training session. The protocol includes bench presses and bicep curls performed at 100% of the individual's 8-rep max, for 4 sets of 8 reps, with standardized rest intervals between sets of 2 minutes. The total duration of the session is approximately 20-25 minutes .Immediately after the resistance exercises, they will complete a structured static stretching protocol targeting the trained muscle groups (pectoralis and elbow flexor), with each stretch held for about 30 seconds and repeated for several sets. The additional stretching lasts 12 minutes, for a total session duration of about 30-35 minutes. | Other | RT+SS |
Primary outcome
Rate-Pressure Product (RPP)
Time frame: 3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)
Rate-pressure product (RPP) will be used as an index of myocardial workload and hemodynamic load during early post-exercise recovery. RPP will be calculated as heart rate multiplied by systolic blood pressure (Omron MX3 Plus). Heart rate and systolic blood pressure will be measured under standardized resting conditions at each time point.
Local Muscle Oxygen Saturation (SmO₂)
Time frame: Time Frame: 3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)
Local muscle oxygen saturation (SmO₂) will be assessed using near-infrared spectroscopy (Moxy Monitor). The sensor will be positioned over the target muscle region and secured to minimize movement artifacts. SmO₂ will be recorded as a local index of the balance between oxygen delivery and oxygen utilization within the sampled muscle region.
3 secondary outcomes
Brachial Artery diameter
Time frame: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
Tissue Hardness (TH)
Time frame: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
Pain pressure Threshold(PPT)
Time frame: Time Frame: 3 times (Baseline, immediately after intervention, and 30 minutes after intervention) for each condition (CC, RT, RT+SS)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Resistance Training and Resistance training + Static Stretching in people with Healthy and Healthy Subjects (HS), run by University of Palermo at 1 site in Italy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Rate-Pressure Product (RPP) (time frame: 3 times (Baseline, immediately after intervantion and 30 minutes after intervention) for each condition (CC, RT, RT+ST)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jun 2026.